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Journal Articles

Abstract 1223: KDM6A orchestrates NK cell response via CD38/48 regulation in multiple myeloma

Jiye Liu, Lijie Xing, Jiang Li, Kenneth Wen, Ning Liu, Yuntong Liu, Annamaria Gulla, Nikhil Munshi, Teru Hideshima, Kenneth Carl Anderson
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1223.
https://doi.org/10.1158/1538-7445.AM2024-1223
Published: 22 March 2024
View article titled, Abstract 1223: KDM6A orchestrates NK cell response <em>via</em> CD38/48 regulation in multiple myeloma
Journal Articles

Retraction: Cytokines Modulate Telomerase Activity in a Human Multiple Myeloma Cell Line

Masaharu Akiyama, Teru Hideshima, Toshiaki Hayashi, Yu-Tzu Tai, Constantine S. Mitsiades, Nicholas Mitsiades, Dharminder Chauhan, Paul Richardson, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2024) 84 (6): 940.
https://doi.org/10.1158/0008-5472.CAN-24-0516
Published: 15 March 2024
View article titled, Retraction: Cytokines Modulate Telomerase Activity in a Human Multiple Myeloma Cell Line
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Journal Articles

Retraction: Nuclear Factor-κB p65 Mediates Tumor Necrosis Factor α-induced Nuclear Translocation of Telomerase Reverse Transcriptase Protein

Masaharu Akiyama, Teru Hideshima, Toshiaki Hayashi, Yu-Tzu Tai, Constantine S. Mitsiades, Nicholas Mitsiades, Dharminder Chauhan, Paul Richardson, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2024) 84 (6): 939.
https://doi.org/10.1158/0008-5472.CAN-24-0517
Published: 15 March 2024
View article titled, Retraction: Nuclear Factor-κB p65 Mediates Tumor Necrosis Factor α-induced Nuclear Translocation of Telomerase Reverse Transcriptase Protein
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Journal Articles

Retraction: Effects of Oligonucleotide N3′→P5′ Thio-phosphoramidate (GRN163) Targeting Telomerase RNA in Human Multiple Myeloma Cells

Masaharu Akiyama, Teru Hideshima, Masood A. Shammas, Toshiaki Hayashi, Makoto Hamasaki, Yu-Tzu Tai, Paul Richardson, Sergei Gryaznov, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2024) 84 (6): 937.
https://doi.org/10.1158/0008-5472.CAN-24-0518
Published: 15 March 2024
View article titled, Retraction: Effects of Oligonucleotide N3′→P5′ Thio-phosphoramidate (GRN163) Targeting Telomerase RNA in Human Multiple Myeloma Cells
Open the PDF for Retraction: Effects of Oligonucleotide N3′→P5′ Thio-phosphoramidate (GRN163) Targeting Telomerase RNA in Human Multiple Myeloma Cells in another window
Journal Articles

Retraction: Insulin-like Growth Factor-1 Induces Adhesion and Migration in Human Multiple Myeloma Cells via Activation of β1-Integrin and Phosphatidylinositol 3′-Kinase/AKT Signaling

Yu-Tzu Tai, Klaus Podar, Laurence Catley, Yu-Hua Tseng, Masaharu Akiyama, Reshma Shringarpure, Renate Burger, Teru Hideshima, Dharminder Chauhan, Nicholas Mitsiades, Paul Richardson, Nikhil C. Munshi, C. Ronald Kahn, Constantine Mitsiades, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2024) 84 (6): 938.
https://doi.org/10.1158/0008-5472.CAN-24-0519
Published: 15 March 2024
View article titled, Retraction: Insulin-like Growth Factor-1 Induces Adhesion and Migration in Human Multiple Myeloma Cells via Activation of β1-Integrin and Phosphatidylinositol 3′-Kinase/AKT Signaling
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Journal Articles

Retraction: Mechanisms by which SGN-40, a Humanized Anti-CD40 Antibody, Induces Cytotoxicity in Human Multiple Myeloma Cells: Clinical Implications

Yu-Tzu Tai, Laurence P. Catley, Constantine S. Mitsiades, Renate Burger, Klaus Podar, Reshma Shringpaure, Teru Hideshima, Dharminder Chauhan, Makoto Hamasaki, Kenji Ishitsuka, Paul Richardson, Steven P. Treon, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2024) 84 (6): 936.
https://doi.org/10.1158/0008-5472.CAN-24-0520
Published: 15 March 2024
View article titled, Retraction: Mechanisms by which SGN-40, a Humanized Anti-CD40 Antibody, Induces Cytotoxicity in Human Multiple Myeloma Cells: Clinical Implications
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Journal Articles

Abstract 5352: Genome-wide CRISPR-cas9 screening identifies KDM6A as a modulator of CD38 expression in multiple myeloma: Therapeutic implications

Jiye Liu, Lijie Xing, Teru Hideshima, Kenneth Carl Anderson
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5352.
https://doi.org/10.1158/1538-7445.AM2022-5352
Published: 15 June 2022
View article titled, Abstract 5352: Genome-wide CRISPR-cas9 screening identifies KDM6A as a modulator of CD38 expression in multiple myeloma: Therapeutic implications
Journal Articles

Abstract LB193: Lysine demethylase 5A is required for MYC driven transcription in multiple myeloma

Jun Qi, hiroto Ohguchi, Paul MC Park, tingjian wang, Kenneth C. Anderson, Teru Hideshima, Catrine Johansson, Udo Oppermann, Adam D. Durbin, Berkley Gryder, Javed Khan, xiaofeng zhang
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB193.
https://doi.org/10.1158/1538-7445.AM2021-LB193
Published: 01 July 2021
View article titled, Abstract LB193: Lysine demethylase 5A is required for MYC driven transcription in multiple myeloma
Journal Articles

Abstract 642: TRAF2 mediates sensitivity to immunomodulatory drugs via NF-κB and ERK signaling in myeloma cells

Jiye Liu, Teru Hideshima, Lijie Xing, Su Wang, Wenrong Zhou, Daisuke Ogiya, Kenneth Wen, Yu-Tzu Tai, Yong Cang, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 642.
https://doi.org/10.1158/1538-7445.AM2020-642
Published: 15 August 2020
View article titled, Abstract 642: TRAF2 mediates sensitivity to immunomodulatory drugs via NF-κB and ERK signaling in myeloma cells
Journal Articles

Abstract 2004: Phenotypic and molecular characterization of inter- and intraclonal heterogeneity in multiple myeloma and Waldenstrom macroglobulinemia

Jana Jakubikova, Danka Cholujova, Teru Hideshima, Jacob Laubach, Nikhil C. Munshi, Steven P. Treon, Paul G. Richardson, Efstathios Kastritis, David M. Dorfman, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2004.
https://doi.org/10.1158/1538-7445.AM2015-2004
Published: 01 August 2015
View article titled, Abstract 2004: Phenotypic and molecular characterization of inter- and intraclonal heterogeneity in multiple myeloma and Waldenstrom macroglobulinemia
Journal Articles

Selective and Potent Akt Inhibition Triggers Anti-Myeloma Activities and Enhances Fatal Endoplasmic Reticulum Stress Induced by Proteasome Inhibition

Naoya Mimura, Teru Hideshima, Toshiyasu Shimomura, Rikio Suzuki, Hiroto Ohguchi, Ola Rizq, Shohei Kikuchi, Yasuhiro Yoshida, Francesca Cottini, Jana Jakubikova, Diana Cirstea, Gullu Gorgun, Jiro Minami, Yu-Tzu Tai, Paul G. Richardson, Teruhiro Utsugi, Atsushi Iwama, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2014) 74 (16): 4458–4469.
https://doi.org/10.1158/0008-5472.CAN-13-3652
Published: 13 August 2014
View article titled, Selective and Potent Akt Inhibition Triggers Anti-Myeloma Activities and Enhances Fatal Endoplasmic Reticulum Stress Induced by Proteasome Inhibition
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Includes: Supplementary data
Journal Articles

miR-30-5p Functions as a Tumor Suppressor and Novel Therapeutic Tool by Targeting the Oncogenic Wnt/β-Catenin/BCL9 Pathway

Jian-Jun Zhao, Jianhong Lin, Di Zhu, Xujun Wang, Daniel Brooks, Ming Chen, Zhang-Bo Chu, Kohichi Takada, Bryan Ciccarelli, Samir Admin, Jianguo Tao, Yu-Tzu Tai, Steven Treon, Geraldine Pinkus, Winston Patrick Kuo, Teru Hideshima, Mary Bouxsein, Nikhil Munshi, Kenneth Anderson, Ruben Carrasco
Journal: Cancer Research
Cancer Res (2014) 74 (6): 1801–1813.
https://doi.org/10.1158/0008-5472.CAN-13-3311-T
Published: 13 March 2014
View article titled, miR-30-5p Functions as a Tumor Suppressor and Novel Therapeutic Tool by Targeting the Oncogenic Wnt/β-Catenin/BCL9 Pathway
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Includes: Supplementary data
Journal Articles

Abstract 2530: Antimyeloma activity of a small molecule multi-targeted kinase inhibitor, AT9283, via potent aurora kinase and STAT3 inhibition

Loredana Santo, Teru Hideshima, Diana Cirstea, Erik A. Nelson, Madhavi L. Bandi, Gullu Gorgun, Sonia Vallet, Samantha Pozzi, Kishan Patel, Hiroshi Ikeda, Giulia Perrone, Yiguo Hu, Dharminder Chauhan, Matthew Squires, Nikhil C. Munshi, Kenneth C. Anderson, Noopur Raje
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2530.
https://doi.org/10.1158/1538-7445.AM10-2530
Published: 15 April 2010
View article titled, Abstract 2530: Antimyeloma activity of a small molecule multi-targeted kinase inhibitor, AT9283, via potent aurora kinase and STAT3 inhibition
Journal Articles

Targeting Angiogenesis via a c-Myc/Hypoxia-Inducible Factor-1α–Dependent Pathway in Multiple Myeloma

Jing Zhang, Martin Sattler, Giovanni Tonon, Clemens Grabher, Samir Lababidi, Alexander Zimmerhackl, Marc S. Raab, Sonia Vallet, Yiming Zhou, Marie-Astrid Cartron, Teru Hideshima, Yu-Tzu Tai, Dharminder Chauhan, Kenneth C. Anderson, Klaus Podar
Journal: Cancer Research
Cancer Res (2009) 69 (12): 5082–5090.
https://doi.org/10.1158/0008-5472.CAN-08-4603
Published: 15 June 2009
View article titled, Targeting Angiogenesis via a c-Myc/Hypoxia-Inducible Factor-1α–Dependent Pathway in Multiple Myeloma
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Includes: Supplementary data
Journal Articles

Abstract #325: CS1 promotes multiple myeloma cell adhesion, clonogenic growth, and tumorigenicity via c-maf-mediated interactions with bone marrow stromal cells

Yu-Tzu Tai, Ender Soydan, Mariateresa Fulciniti, Weihua Song, Kihyun Kim, Fangxin Hong, Xian-Feng Li, Peter Burger, Mathew J Rumizen Mathew J Rumizen, Sabikun Nahar, Klaus Podar Klaus Podar, Dharminder Chauhan, Teru Hideshima, Nikhil Munshi, Giovanni Tonon Giovanni Tonon, Ruben Carrasco, Kenneth Anderson
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 325.
Published: 01 May 2009
View article titled, Abstract #325: CS1 promotes multiple myeloma cell adhesion, clonogenic growth, and tumorigenicity via c-maf-mediated interactions with bone marrow stromal cells
Journal Articles

Abstract #3695: Targeting MEK1/2 signaling cascade by AS703026, a novel selective MEK1/2 inhibitor, induces pleiotropic anti-myeloma activity in vitro and in vivo

Yu-Tzu Tai, Kihyun Kim, Mariateresa Fulciniti, Ender Soydan, Weihua Song, Xian-Feng Li, Matthew Rumizen, Sabikun Nahar, Peter Burger, Teru Hideshima, Paul Richardson, Nikhil Munshi, Ann Clark, Andreas Goutopoulos, Luca Rastelli, Kenneth Kenneth
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3695.
Published: 01 May 2009
View article titled, Abstract #3695: Targeting MEK1/2 signaling cascade by AS703026, a novel selective MEK1/2 inhibitor, induces pleiotropic anti-myeloma activity in vitro and in vivo
Journal Articles

Abstract #2236: Potential therapeutic role of the selective adhesion molecule inhibitor natalizumab (Tysabri) in Multiple Myeloma

Klaus Podar, Alexander Zimmerhackl, Dian Olson, Yu-Tzu Tai, Teru Hideshima, Dharminder Chauhan, Kenneth Anderson
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2236.
Published: 01 May 2009
View article titled, Abstract #2236: Potential therapeutic role of the selective adhesion molecule inhibitor natalizumab (Tysabri) in Multiple Myeloma
Journal Articles

Abstract #318: The CCR1 inhibitor, MLN3897, enhances Velcade inhibition of multiple myeloma (MM)-bone cells interactions

Sonia Vallet, Nileshwari Vaghela, MariaTeresa Fulciniti, Petter Veiby, Kishan Patel, Teru Hideshima, Samantha Pozzi, Loredana Santo, Siddhartha Mukherjee, Diana Cirstea, David Scadden, Kenneth Anderson, Raje Noopur
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 318.
Published: 01 May 2009
View article titled, Abstract #318: The CCR1 inhibitor, MLN3897, enhances Velcade inhibition of multiple myeloma (MM)-bone cells interactions
Journal Articles

Abstract #1994: A novel multi-targeted small molecule inhibitor RGB 286638 triggers apoptosis and necrosis in multiple myeloma via dual cell death pathways

Diana Cirstea, Teru Hideshima, Loredana Santo, Sonia Vallet, Samantha Pozzi, Nileshwari Vaghela, Hiroshi Ikeda, Kishan Patel, Hannes Loferer, Gullu Gorgun, Giulia Perrone, Elisabetta Calabrese, Nikhil Munshi, Kenneth Anderson, Noopur Raje
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1994.
Published: 01 May 2009
View article titled, Abstract #1994: A novel multi-targeted small molecule inhibitor RGB 286638 triggers apoptosis and necrosis in multiple myeloma via dual cell death pathways
Journal Articles

Aplidin, a Marine Organism–Derived Compound with Potent Antimyeloma Activity In vitro and In vivo

Constantine S. Mitsiades, Enrique M. Ocio, Atanasio Pandiella, Patricia Maiso, Consuelo Gajate, Mercedes Garayoa, David Vilanova, Juan Carlos Montero, Nicholas Mitsiades, Ciaran J. McMullan, Nikhil C. Munshi, Teru Hideshima, Dharminder Chauhan, Pablo Aviles, Gabriel Otero, Glynn Faircloth, M. Victoria Mateos, Paul G. Richardson, Faustino Mollinedo, Jesus F. San-Miguel, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2008) 68 (13): 5216–5225.
https://doi.org/10.1158/0008-5472.CAN-07-5725
Published: 01 July 2008
View article titled, Aplidin, a Marine Organism–Derived Compound with Potent Antimyeloma Activity <em>In vitro</em> and <em>In vivo</em>
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Includes: Supplementary data