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Journal Articles

Abstract 2785: Beyond the role of transcobalamin 1 (TCN1) as a vitamin B12-binding protein in hepatocellular carcinoma

Gregory Kenneth Muliawan, Carmen Oi Ning Leung, Terence Kin Wah Lee

Cancer Res (2024) 84 (6_Supplement): 2785.

https://doi.org/10.1158/1538-7445.AM2024-2785

Published: 22 March 2024

View article titled, Abstract 2785: Beyond the role of transcobalamin 1 (TCN1) as a vitamin B12-binding protein in hepatocellular carcinoma

Journal Articles

Abstract 3288: Identification of Annexin A1 as a novel driver of lenvatinib resistance in hepatocellular carcinoma

Catherine Yujia GU, Carmen Oi Ning LEUNG, Terence Kin Wah LEE

Cancer Res (2024) 84 (6_Supplement): 3288.

https://doi.org/10.1158/1538-7445.AM2024-3288

Published: 22 March 2024

View article titled, Abstract 3288: Identification of Annexin A1 as a novel driver of lenvatinib resistance in hepatocellular carcinoma

Journal Articles

Abstract 5431: Identification of serine/threonine kinase 39 (STK39) as a driver for multidrug resistance in hepatocellular carcinoma

Carmen Oi Ning Leung, Terence Kin-Wah Lee

Cancer Res (2024) 84 (6_Supplement): 5431.

https://doi.org/10.1158/1538-7445.AM2024-5431

Published: 22 March 2024

View article titled, Abstract 5431: Identification of serine/threonine kinase 39 (STK39) as a driver for multidrug resistance in hepatocellular carcinoma

Journal Articles

Abstract 7597: Therapeutic potential of ketogenic diet as an adjuvant to lenvatinib treatment in hepatocellular carcinoma

Minghe Zhang, Terence Kin-Wah Lee, Stephanie Ma, Man Tong

Cancer Res (2024) 84 (6_Supplement): 7597.

https://doi.org/10.1158/1538-7445.AM2024-7597

Published: 22 March 2024

View article titled, Abstract 7597: Therapeutic potential of ketogenic diet as an adjuvant to lenvatinib treatment in hepatocellular carcinoma

Journal Articles

Abstract 574: Adipocyte-derived FABP4 promotes non-alcoholic fatty liver disease (NAFLD)-induced hepatocellular carcinoma by driving ITGB1-mediated β-catenin activation

Carmen Oi Ning Leung, Shilpa Gurung, Katherine Po Sin Chung, Sze Man Chan, Terence Kin Wah Lee

Cancer Res (2024) 84 (6_Supplement): 574.

https://doi.org/10.1158/1538-7445.AM2024-574

Published: 22 March 2024

View article titled, Abstract 574: Adipocyte-derived FABP4 promotes non-alcoholic fatty liver disease (NAFLD)-induced hepatocellular carcinoma by driving ITGB1-mediated β-catenin activation

Journal Articles

Abstract 1988: Mass spectrometry profiling identifies ENO2 as a driver of lenvatinib resistance in hepatocellular carcinoma

Sukbum Kim, Jia-Jian Loh, Huajian Yu, Ki-Fong Man, Kai-Yu Ng, Terence Kin-Wah Lee, Clive Yik-Sham Chung, Stephanie Ma

Cancer Res (2024) 84 (6_Supplement): 1988.

https://doi.org/10.1158/1538-7445.AM2024-1988

Published: 22 March 2024

View article titled, Abstract 1988: Mass spectrometry profiling identifies ENO2 as a driver of lenvatinib resistance in hepatocellular carcinoma

Journal Articles

Abstract 2799: Intestinal Akkermansia muciniphila complements the therapeutic efficacy of PD1 therapy by reshaping the immunosuppressive microenvironment in nonalcoholic fatty liver disease (NAFLD)-induced hepatocellular carcinoma

Xueqian Wu, Fan Ying, Katherine Po Sin Chung, Carmen Oi Ning Leung, Terence Kin Wah Lee

Cancer Res (2024) 84 (6_Supplement): 2799.

https://doi.org/10.1158/1538-7445.AM2024-2799

Published: 22 March 2024

View article titled, Abstract 2799: Intestinal <em>Akkermansia muciniphila</em> complements the therapeutic efficacy of PD1 therapy by reshaping the immunosuppressive microenvironment in nonalcoholic fatty liver disease (NAFLD)-induced hepatocellular carcinoma

Journal Articles

Abstract 5546: CRISPR-based kinome screen identifies Ikbkb as a regulator of phagocytic evasion in hepatocellular carcinoma

Sze Man Chan, Terence Kin Wah Lee

Cancer Res (2024) 84 (6_Supplement): 5546.

https://doi.org/10.1158/1538-7445.AM2024-5546

Published: 22 March 2024

View article titled, Abstract 5546: CRISPR-based kinome screen identifies <em>Ikbkb</em> as a regulator of phagocytic evasion in hepatocellular carcinoma

Journal Articles

Abstract 5356: Wild type Kirsten rat sarcoma (Kras) activation drives evasion of interferon-mediated immunity in hepatocellular carcinoma

Mang Leng Lei, Terence Kin Wah Lee

Cancer Res (2024) 84 (6_Supplement): 5356.

https://doi.org/10.1158/1538-7445.AM2024-5356

Published: 22 March 2024

View article titled, Abstract 5356: Wild type Kirsten rat sarcoma (Kras) activation drives evasion of interferon-mediated immunity in hepatocellular carcinoma

Journal Articles

Abstract 2449: p38β promotes cancer stemness and chemoresistance in hepatocellular carcinoma

Ianto Bosheng Huang, Yunong Xie, Tin Lok Wong, Terence Kin Wah Lee, Jing-Ping Yun, Stephanie Kwai Yee Ma, Man Tong

Cancer Res (2023) 83 (7_Supplement): 2449.

https://doi.org/10.1158/1538-7445.AM2023-2449

Published: 04 April 2023

View article titled, Abstract 2449: p38β promotes cancer stemness and chemoresistance in hepatocellular carcinoma

Journal Articles

Abstract 2443: Serine/threonine kinase 39 (STK39) regulates cancer stemness through regulating PARP-mediated SOX2/OCT4 expression in hepatocellular carcinoma

Carmen Oi Ning Leung, Terence Kin-Wah Lee

Cancer Res (2023) 83 (7_Supplement): 2443.

https://doi.org/10.1158/1538-7445.AM2023-2443

Published: 04 April 2023

View article titled, Abstract 2443: Serine/threonine kinase 39 (STK39) regulates cancer stemness through regulating PARP-mediated SOX2/OCT4 expression in hepatocellular carcinoma

Journal Articles

Caspase-3–Induced Activation of SREBP2 Drives Drug Resistance via Promotion of Cholesterol Biosynthesis in Hepatocellular Carcinoma

Cancer Res (2022) 82 (17): 3102–3115.

https://doi.org/10.1158/0008-5472.CAN-21-2934

Published: 02 September 2022

View article titled, Caspase-3–Induced Activation of SREBP2 Drives Drug Resistance via Promotion of Cholesterol Biosynthesis in Hepatocellular Carcinoma

Includes: Supplementary data

Journal Articles

Abstract 1996: Nuclear factor (erythroid-derived 2)-like 2 promotes tumor-initiating cell lineage and drug resistance in hepatocellular carcinoma

Hoi Wing Leung, Terence Kin Wah Lee

Cancer Res (2018) 78 (13_Supplement): 1996.

https://doi.org/10.1158/1538-7445.AM2018-1996

Published: 01 July 2018

View article titled, Abstract 1996: Nuclear factor (erythroid-derived 2)-like 2 promotes tumor-initiating cell lineage and drug resistance in hepatocellular carcinoma

Journal Articles

Abstract 4496: Myofibroblast-secreted follistatin-like 1 promotes hepatocellular carcinoma formation and metastasis

Natalie Tsz Wai Li, Man Tong, Lei Zhou, Wen Ning, Chung-Mau Lo, Kwan Man, Terence Kin-Wah Lee, Stephanie Kwai-Yee Ma

Cancer Res (2018) 78 (13_Supplement): 4496.

https://doi.org/10.1158/1538-7445.AM2018-4496

Published: 01 July 2018

View article titled, Abstract 4496: Myofibroblast-secreted follistatin-like 1 promotes hepatocellular carcinoma formation and metastasis

Journal Articles

Abstract 1432: Deranged tyrosine metabolism drives tumorigenesis in liver cancer

Man Tong, Tin Lok Wong, Steve Tin-Chi Luk, Noelia Che, Xin Yuan Guan, Yun Fei Yuan, Terence Kin-Wah Lee, Stephanie Ma

Cancer Res (2018) 78 (13_Supplement): 1432.

https://doi.org/10.1158/1538-7445.AM2018-1432

Published: 01 July 2018

View article titled, Abstract 1432: Deranged tyrosine metabolism drives tumorigenesis in liver cancer

Journal Articles

Abstract 1988: The pivotal roles of adipocytes on regulation of cancer stemness and drug resistance in hepatocellular carcinoma

Shilpa Gurung, Terence Kin-Wah Lee

Cancer Res (2018) 78 (13_Supplement): 1988.

https://doi.org/10.1158/1538-7445.AM2018-1988

Published: 01 July 2018

View article titled, Abstract 1988: The pivotal roles of adipocytes on regulation of cancer stemness and drug resistance in hepatocellular carcinoma

Journal Articles

Abstract 1003: Targeting liver-tumor initiating cells via hampering the lipogenesis pathways through stearoyl - CoA desaturase

Kin Fai Ma, Jessica Lo, Eunice Yuen-Ting Lau, John A. Copland, Irene Oi-Lin Ng, Terence Kin-Wah Lee

Cancer Res (2016) 76 (14_Supplement): 1003.

https://doi.org/10.1158/1538-7445.AM2016-1003

Published: 15 July 2016

View article titled, Abstract 1003: Targeting liver-tumor initiating cells via hampering the lipogenesis pathways through stearoyl - CoA desaturase

Journal Articles

Abstract 2317: Cancer-associated fibroblast-derived HGF regulates cancer stem cell-like properties in hepatocellular carcinoma through c-Met/FRA1/HEY1 signaling pathway

Yuen Ting Lau, Jessica Lo, Irene Oi Lin Ng, Terence Kin Wah Lee

Cancer Res (2015) 75 (15_Supplement): 2317.

https://doi.org/10.1158/1538-7445.AM2015-2317

Published: 01 August 2015

View article titled, Abstract 2317: Cancer-associated fibroblast-derived HGF regulates cancer stem cell-like properties in hepatocellular carcinoma through c-Met/FRA1/HEY1 signaling pathway

Journal Articles

Abstract LB-53: Regulatory role of miR-142-3p on the functional hepatic cancer stem cell marker CD133

Kai Y. Ng, Stella Chai, Man Tong, Pak Shing Kwan, Yuen Piu Chan, Terence Kin Wah Lee, Nathalie Wong, Xin-Yuan Guan, Stephanie Ma

Cancer Res (2014) 74 (19_Supplement): LB-53.

https://doi.org/10.1158/1538-7445.AM2014-LB-53

Published: 01 October 2014

View article titled, Abstract LB-53: Regulatory role of miR-142-3p on the functional hepatic cancer stem cell marker CD133

Journal Articles

Abstract 1911: NF-κB mediated CD47 upregulation promotes sorafenib resistance and its blockade synergizes the effect of sorafenib in hepatocellular carcinoma

Jessica Lo, Eunice Yuen Ting Lau, Irene Oi Lin Ng, Terence Kin Wah Lee

Cancer Res (2014) 74 (19_Supplement): 1911.

https://doi.org/10.1158/1538-7445.AM2014-1911

Published: 01 October 2014

View article titled, Abstract 1911: NF-κB mediated CD47 upregulation promotes sorafenib resistance and its blockade synergizes the effect of sorafenib in hepatocellular carcinoma

NARROW

Abstract 2785: Beyond the role of transcobalamin 1 (TCN1) as a vitamin B12-binding protein in hepatocellular carcinoma

Abstract 3288: Identification of Annexin A1 as a novel driver of lenvatinib resistance in hepatocellular carcinoma

Abstract 5431: Identification of serine/threonine kinase 39 (STK39) as a driver for multidrug resistance in hepatocellular carcinoma

Abstract 7597: Therapeutic potential of ketogenic diet as an adjuvant to lenvatinib treatment in hepatocellular carcinoma

Abstract 574: Adipocyte-derived FABP4 promotes non-alcoholic fatty liver disease (NAFLD)-induced hepatocellular carcinoma by driving ITGB1-mediated β-catenin activation

Abstract 1988: Mass spectrometry profiling identifies ENO2 as a driver of lenvatinib resistance in hepatocellular carcinoma

Abstract 2799: Intestinal Akkermansia muciniphila complements the therapeutic efficacy of PD1 therapy by reshaping the immunosuppressive microenvironment in nonalcoholic fatty liver disease (NAFLD)-induced hepatocellular carcinoma

Abstract 5546: CRISPR-based kinome screen identifies Ikbkb as a regulator of phagocytic evasion in hepatocellular carcinoma

Abstract 5356: Wild type Kirsten rat sarcoma (Kras) activation drives evasion of interferon-mediated immunity in hepatocellular carcinoma

Abstract 2449: p38β promotes cancer stemness and chemoresistance in hepatocellular carcinoma

Abstract 2443: Serine/threonine kinase 39 (STK39) regulates cancer stemness through regulating PARP-mediated SOX2/OCT4 expression in hepatocellular carcinoma

Caspase-3–Induced Activation of SREBP2 Drives Drug Resistance via Promotion of Cholesterol Biosynthesis in Hepatocellular Carcinoma

Abstract 1996: Nuclear factor (erythroid-derived 2)-like 2 promotes tumor-initiating cell lineage and drug resistance in hepatocellular carcinoma

Abstract 4496: Myofibroblast-secreted follistatin-like 1 promotes hepatocellular carcinoma formation and metastasis

Abstract 1432: Deranged tyrosine metabolism drives tumorigenesis in liver cancer

Abstract 1988: The pivotal roles of adipocytes on regulation of cancer stemness and drug resistance in hepatocellular carcinoma

Abstract 1003: Targeting liver-tumor initiating cells via hampering the lipogenesis pathways through stearoyl - CoA desaturase

Abstract 2317: Cancer-associated fibroblast-derived HGF regulates cancer stem cell-like properties in hepatocellular carcinoma through c-Met/FRA1/HEY1 signaling pathway

Abstract LB-53: Regulatory role of miR-142-3p on the functional hepatic cancer stem cell marker CD133

Abstract 1911: NF-κB mediated CD47 upregulation promotes sorafenib resistance and its blockade synergizes the effect of sorafenib in hepatocellular carcinoma

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