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Tej K. Pandita
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Journal Articles

Abstract 335: Ubiquitin Specific Peptidase 37promotes Osteosarcoma oncogenesis by interacting with PCNA and impacting constitutive replication fork movement.

Free
Ravi Chauhan, Lakshay Malhotra, Ashna Gupta, Ajaz Bhat, Gunjan Dagar, Tariq Masoodi, Muzafar A. Macha, Ethayathulla Abdul Samath, Atul Batra, Mehar Chand Sharma, Mohammad Haris, Ammira Al-Shabeeb Akil, Tej K. Pandita, Shahab Uddin, Mayank Singh
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 335.
https://doi.org/10.1158/1538-7445.AM2023-335
Published: 04 April 2023
View articletitled, Abstract 335: Ubiquitin Specific Peptidase 37promotes Osteosarcoma oncogenesis by interacting with PCNA and impacting constitutive replication fork movement.
Journal Articles

Epigenetic–Metabolic Interplay in the DNA Damage Response and Therapeutic Resistance of Breast Cancer

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Chandrima Das, Swagata Adhikari, Apoorva Bhattacharya, Sanjukta Chakraborty, Payel Mondal, Shalini S. Yadav, Santanu Adhikary, Clayton R. Hunt, Kamlesh K. Yadav, Shruti Pandita, Siddhartha Roy, John A. Tainer, Zamal Ahmed, Tej K. Pandita
Journal: Cancer Research
Cancer Res (2023) 83 (5): 657–666.
https://doi.org/10.1158/0008-5472.CAN-22-3015
Published: 02 March 2023
View articletitled, Epigenetic–Metabolic Interplay in the DNA Damage Response and Therapeutic Resistance of Breast Cancer
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Journal Articles

CDKN2A/p16 Deletion in Head and Neck Cancer Cells Is Associated with CDK2 Activation, Replication Stress, and Vulnerability to CHK1 Inhibition

Free
Mayur A. Gadhikar, Jiexin Zhang, Li Shen, Xiayu Rao, Jing Wang, Mei Zhao, Nene N. Kalu, Faye M. Johnson, Lauren A. Byers, John Heymach, Walter N. Hittelman, Durga Udayakumar, Raj K. Pandita, Tej K. Pandita, Curtis R. Pickering, Abena B. Redwood, Helen Piwnica-Worms, Katharina Schlacher, Mitchell J. Frederick, Jeffrey N. Myers
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (3): 781–797.
https://doi.org/10.1158/0008-5472.CAN-17-2802
Published: 31 January 2018
View articletitled, CDKN2A/p16 Deletion in Head and Neck Cancer Cells Is Associated with CDK2 Activation, Replication Stress, and Vulnerability to CHK1 Inhibition
Open the PDF for CDKN2A/p16 Deletion in Head and Neck Cancer Cells Is Associated with CDK2 Activation, Replication Stress, and Vulnerability to CHK1 Inhibition in another window
Includes: Supplementary data
Journal Articles

Abstract 2335: Targeting the DNA repair as well as survival functions of MCL-1 enhances cancer cell killing

Free
Abid Mattoo, J Milburn Milburn Jessup, Tej K. Pandita
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2335.
https://doi.org/10.1158/1538-7445.AM2017-2335
Published: 01 July 2017
View articletitled, Abstract 2335: Targeting the DNA repair as well as survival functions of MCL-1 enhances cancer cell killing
Journal Articles

Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis

Free
Daria G. Valerio, Haiming Xu, Chun-Wei Chen, Takayuki Hoshii, Meghan E. Eisold, Christopher Delaney, Monica Cusan, Aniruddha J. Deshpande, Chun-Hao Huang, Amaia Lujambio, YuJun George Zheng, Johannes Zuber, Tej K. Pandita, Scott W. Lowe, Scott A. Armstrong
Journal: Cancer Research
Cancer Res (2017) 77 (7): 1753–1762.
https://doi.org/10.1158/0008-5472.CAN-16-2374
Published: 02 April 2017
View articletitled, Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis
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Includes: Supplementary data
Journal Articles

HOXC10 Expression Supports the Development of Chemotherapy Resistance by Fine Tuning DNA Repair in Breast Cancer Cells

Free
Helen Sadik, Preethi Korangath, Nguyen K. Nguyen, Balazs Gyorffy, Rakesh Kumar, Mohammad Hedayati, Wei Wen Teo, Sunju Park, Hardik Panday, Teresa Gonzalez Munoz, Otilia Menyhart, Nilay Shah, Raj K. Pandita, Jenny C. Chang, Theodore DeWeese, Howard Y. Chang, Tej K. Pandita, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2016) 76 (15): 4443–4456.
https://doi.org/10.1158/0008-5472.CAN-16-0774
Published: 31 July 2016
View articletitled, HOXC10 Expression Supports the Development of Chemotherapy Resistance by Fine Tuning DNA Repair in Breast Cancer Cells
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Includes: Supplementary data
Journal Articles

Abstract 2756: SMARCAD1 depletion enhances hyperthermia-mediated radiosensitization by decreasing resection and enhancing stalled replication forks

Free
Sharmistha Chakraborty, Clayton R. Hunt, Shashank Hambarde, Kalpana Mujoo, Nobuo Horikoshi, Raj K. Pandita, Abid Mattoo, Bin Teh, Tej K. Pandita
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2756.
https://doi.org/10.1158/1538-7445.AM2016-2756
Published: 15 July 2016
View articletitled, Abstract 2756: SMARCAD1 depletion enhances hyperthermia-mediated radiosensitization by decreasing resection and enhancing stalled replication forks
Journal Articles

Abstract 3530: Hsp90-Tom70 interaction facilitates ATM localization to mitochondria and induces mitochondrial autophagy

Free
Aloke K. Sarkar, Tej K. Pandita, Varsha Gandhi
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3530.
https://doi.org/10.1158/1538-7445.AM2016-3530
Published: 15 July 2016
View articletitled, Abstract 3530: Hsp90-Tom70 interaction facilitates ATM localization to mitochondria and induces mitochondrial autophagy
Journal Articles

Abstract 3594: The TGF-β effector β2SP depletion abrogates DNA damage repair

Free
Jian Chen, Vivek Shukla, Jiun-Sheng Chen, Raj K. Panditab, Yun Seong Jeong, Lior H Katz, Ji-Hyun Shin, YoungJin Gi, Lawrence N. Kwongc, Clayton R. Huntb, Patrizia Farci, Xiaoping Su, Jon White, Bibhuti Mishra, Asif Rashid, Milind Javle, Lei Li, Junjie Chen, John R Stroehlein, Marta Davila, Rehan Akbani, Keigo Machidao, Hidekazu Tsukamoto, Tej K. Pandita, Lopa Mishra
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3594.
https://doi.org/10.1158/1538-7445.AM2016-3594
Published: 15 July 2016
View articletitled, Abstract 3594: The TGF-β effector β2SP depletion abrogates DNA damage repair
Journal Articles

Abstract 2694: Histone acetyltransferase activity of MOF is required for MLL-AF9 leukemogenesis

Free
Daria G. Valerio, Haiming Xu, Chun-Wei Chen, Takayuki Hoshii, Meghan Eisold, Christopher Delaney, Monica Cusan, Aniruddha J. Deshpande, Chun-Hao Huang, Amaia Lujambio, George Zheng, Tej K. Pandita, Scott W. Lowe, Scott A. Armstrong
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2694.
https://doi.org/10.1158/1538-7445.AM2016-2694
Published: 15 July 2016
View articletitled, Abstract 2694: Histone acetyltransferase activity of MOF is required for MLL-AF9 leukemogenesis
Journal Articles

Abstract 518: Ionizing radiation-induced DNA damage response decreases during induced pluripotent and embryonic stem cell differentiation

Free
Kalpana Mujoo, Raj K. Pandita, Anjana Tiwari, Vijay Charaka, Walter N. Hittelman, Murlidhar Hegde, Haibo Wang, Clayton R. Hunt, Bhuvanesh Dave, Jenny Chang, E Brian Butler, Tej K. Pandita
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 518.
https://doi.org/10.1158/1538-7445.AM2016-518
Published: 15 July 2016
View articletitled, Abstract 518: Ionizing radiation-induced DNA damage response decreases during induced pluripotent and embryonic stem cell differentiation
Journal Articles

Abstract 2852: Torin2 suppresses ionizing radiation induced DNA damage repair

Free
Durga Udayakumar, Raj K. Pandita, Nobuo Horikoshi, Clayton R. Hunt, Qingsong Liu, Kwok-Kin Wong, Nathanael S. Gray, Tej K. Pandita, Kenneth D. Westover
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2852.
https://doi.org/10.1158/1538-7445.AM2015-2852
Published: 01 August 2015
View articletitled, Abstract 2852: Torin2 suppresses ionizing radiation induced DNA damage repair
Journal Articles

Abstract 3900: Genomic landscape of human cancer reveals dysregulated TGF-β signaling with prognostic significance

Free
Jian Chen, Jiun-Sheng Chen, Jianping Zhang, Liem Phan, Nina M. Muñoz, Lior H Katz, YoungJin Gi, Vipin Kumar Menon, Ji-Hyun Shin, Yun Seong Jeong, Wilma Jogunoori, Patrizia Farci, Kirti Shetty, Xiaoping Su, Tej K Pandita, Jon White, Bibhuti Mishra, Fausto Zamboni, Xifeng Wu, Asif Rashid, Shulin Li, Milind Javle, Mien-Chie Hung, Franklin Herlong, Marta Davila, John Stroehlein, Kenna R Shaw, Xuemei Wang, Jeffrey S Morris, Rehan Akbani, Lopa Mishra
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3900.
https://doi.org/10.1158/1538-7445.AM2015-3900
Published: 01 August 2015
View articletitled, Abstract 3900: Genomic landscape of human cancer reveals dysregulated TGF-β signaling with prognostic significance
Journal Articles

Single-Strand DNA-Binding Protein SSB1 Facilitates TERT Recruitment to Telomeres and Maintains Telomere G-Overhangs

Free
Raj K. Pandita, Tracy T. Chow, Durga Udayakumar, Amanda L. Bain, Liza Cubeddu, Clayton R. Hunt, Wei Shi, Nobuo Horikoshi, Yong Zhao, Woodring E. Wright, Kum Kum Khanna, Jerry W. Shay, Tej K. Pandita
Journal: Cancer Research
Cancer Res (2015) 75 (5): 858–869.
https://doi.org/10.1158/0008-5472.CAN-14-2289
Published: 01 March 2015
View articletitled, Single-Strand DNA-Binding Protein SSB1 Facilitates TERT Recruitment to Telomeres and Maintains Telomere G-Overhangs
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Includes: Supplementary data
Journal Articles

Abstract 2250: Role of single strand binding protein 1 in TERT recruitment to telomeres and in maintaining telomere G-overhangs

Free
Tej K. Pandita, Raj Pandita
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2250.
https://doi.org/10.1158/1538-7445.AM2014-2250
Published: 01 October 2014
View articletitled, Abstract 2250: Role of single strand binding protein 1 in TERT recruitment to telomeres and in maintaining telomere G-overhangs
Journal Articles

Abstract 5139: MOF cooperates with DNA polymerase eta to repair intrastrand break induced by crosslinking agents

Free
Mayank Singh, Arun Gupta, Komal Komal, Tej K. Pandita
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5139.
https://doi.org/10.1158/1538-7445.AM2014-5139
Published: 01 October 2014
View articletitled, Abstract 5139: MOF cooperates with DNA polymerase eta to repair intrastrand break induced by crosslinking agents
Journal Articles

Epigenetic Inactivation of the Potential Tumor Suppressor Gene FOXF1 in Breast Cancer

Free
Pang-Kuo Lo, Ji Shin Lee, Xiaohui Liang, Liangfeng Han, Tsuyoshi Mori, Mary Jo Fackler, Helen Sadik, Pedram Argani, Tej K. Pandita, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2010) 70 (14): 6047–6058.
https://doi.org/10.1158/0008-5472.CAN-10-1576
Published: 14 July 2010
View articletitled, Epigenetic Inactivation of the Potential Tumor Suppressor Gene FOXF1 in Breast Cancer
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Includes: Supplementary data
Journal Articles

Negative Regulation of AKT Activation by BRCA1

Free
Tao Xiang, Amiko Ohashi, Yuping Huang, Tej K. Pandita, Thomas Ludwig, Simon N. Powell, Qin Yang
Journal: Cancer Research
Cancer Res (2008) 68 (24): 10040–10044.
https://doi.org/10.1158/0008-5472.CAN-08-3009
Published: 15 December 2008
View articletitled, Negative Regulation of AKT Activation by BRCA1
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Includes: Supplementary data
Journal Articles

Inhibition of Telomerase Activity Enhances Hyperthermia-Mediated Radiosensitization

Free
Manjula Agarwal, Shruti Pandita, Clayton R. Hunt, Arun Gupta, Xuan Yue, Saira Khan, Raj K. Pandita, David Pratt, Jerry W. Shay, John-Stephen A. Taylor, Tej K. Pandita
Journal: Cancer Research
Cancer Res (2008) 68 (9): 3370–3378.
https://doi.org/10.1158/0008-5472.CAN-07-5831
Published: 01 May 2008
View articletitled, Inhibition of Telomerase Activity Enhances Hyperthermia-Mediated Radiosensitization
Open the PDF for Inhibition of Telomerase Activity Enhances Hyperthermia-Mediated Radiosensitization in another window
Includes: Supplementary data
Journal Articles

Hyperthermia Activates a Subset of Ataxia-Telangiectasia Mutated Effectors Independent of DNA Strand Breaks and Heat Shock Protein 70 Status

Free
Clayton R. Hunt, Raj K. Pandita, Andrei Laszlo, Ryuji Higashikubo, Manjula Agarwal, Tetsuya Kitamura, Arun Gupta, Nicole Rief, Nobuo Horikoshi, Rajeskaran Baskaran, Ji-Hoon Lee, Markus Löbrich, Tanya T. Paull, Joseph L. Roti Roti, Tej K. Pandita
Journal: Cancer Research
Cancer Res (2007) 67 (7): 3010–3017.
https://doi.org/10.1158/0008-5472.CAN-06-4328
Published: 04 April 2007
View articletitled, Hyperthermia Activates a Subset of Ataxia-Telangiectasia Mutated Effectors Independent of DNA Strand Breaks and Heat Shock Protein 70 Status
Open the PDF for Hyperthermia Activates a Subset of Ataxia-Telangiectasia Mutated Effectors Independent of DNA Strand Breaks and Heat Shock Protein 70 Status in another window