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Journal Articles

Abstract LB004: Deciphering oncogenic dedifferentiation: A proteomic approach to quantifying stemness scores and unveiling druggable targets

Free
Iga Kołodziejczak-Guglas, Renan Simões, Elizabeth G. Demicco, Rossana L. Segura, Alexander J. Lazar, Weiping Ma, Erik Storrs, Francesca Petralia, Antonio Colaprico, Felipe da Leprevost, Pietro Pugliese, Michele Ceccarelli, Alexey I. Nesvizhski, Bożena Kamińska, Bing Zhang, Henry Rodriguez, Mehdi Mesri, Ana I. Robles, Clinical Proteomic Tumor Analysis Consortium, Li Ding, Tathiane M. Malta, Maciej Wiznerowicz
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB004.
https://doi.org/10.1158/1538-7445.AM2024-LB004
Published: 05 April 2024
View articletitled, Abstract LB004: Deciphering oncogenic dedifferentiation: A proteomic approach to quantifying stemness scores and unveiling druggable targets
Journal Articles

The Epigenetic Evolution of Glioma Is Determined by the IDH1 Mutation Status and Treatment Regimen

Open Access
Tathiane M. Malta, Thais S. Sabedot, Natalia S. Morosini, Indrani Datta, Luciano Garofano, Wies Vallentgoed, Frederick S. Varn, Kenneth Aldape, Fulvio D'Angelo, Spyridon Bakas, Jill S. Barnholtz-Sloan, Hui K. Gan, Mohammad Hasanain, Ann-Christin Hau, Kevin C. Johnson, Simona Cazacu, Ana C. deCarvalho, Mustafa Khasraw, Emre Kocakavuk, Mathilde C.M. Kouwenhoven, Simona Migliozzi, Simone P. Niclou, Johanna M. Niers, D. Ryan Ormond, Sun Ha Paek, Guido Reifenberger, Peter A. Sillevis Smitt, Marion Smits, Lucy F. Stead, Martin J. van den Bent, Erwin G. Van Meir, Annemiek Walenkamp, Tobias Weiss, Michael Weller, Bart A. Westerman, Bauke Ylstra, Pieter Wesseling, Anna Lasorella, Pim J. French, Laila M. Poisson, Consortium The GLASS, Adelheid Woehrer, Allison K Lowman, Ana C deCarvalho, Ana Valeria Castro, Andrea Transou, Andrew R Brodbelt, Ann-Christin Hau, Anna Lasorella, Anna Golebiewska, Annemiek Walenkamp, Annette M Molinaro, Antonio Iavarone, Azzam Ismail, Bart A Westerman, Bauke Ylstra, Christoph Bock, D. Ryan Ormond, Daniel J Brat, Emre Kocakavuk, Erwin G Van Meir, Floris P Barthel, Frederick S Varn, Fulvio D'Angelo, Gaetano Finocchiaro, Ganesh Rao, Gelareh Zadeh, Guido Reifenberger, Ho Keu ngNg, Hoon Kim, Houtan Noushmehr, Hrvoje Miletic, Hui K Gan, Indrani Datta, Jack Rock, James M Snyder, Jason T Huse, Jennifer M Connelly, Jill S Barnholtz-Sloan, Johanna M Niers, John F deGroot, Kadir C Akdemir, Kasthuri S Kannan, Keith L Ligon, Kenneth Aldape, Ketan R Bulsara, Kevin C Johnson, Kristin D Alfaro, Laila M Poisson, Luciano Garofano, Lucy F Stead, MacLean P Nasrallah, Marion Smits, Martin J van den Bent, Mathilde CM Kouwenhoven, Michael Weller, Mohammad Hasanain, Mustafa Khasraw, Peter V Gould, Peter A Sillevis Smitt, Peter S LaViolette, Philip D Tatman, Pieter Wesseling, Pim J French, Rameen Beroukhim, Roel G.W. Verhaak, Simona Migliozzi, Simone P Niclou, Spyridon Bakas, Steven Kalkanis, Sun Ha Paek, Susan C Short, Tabatabai Ghazaleh, Tathiane M Malta, Thais S Sabedot, Tobias Weiss, Tobias Walbert, Ujjwal Baid, Wies Vallentgoed, W. K. Alfred Yung, Roel G.W. Verhaak, Antonio Iavarone, Houtan Noushmehr
Journal: Cancer Research
Cancer Res (2024) 84 (5): 741–756.
https://doi.org/10.1158/0008-5472.CAN-23-2093
Published: 04 March 2024
View articletitled, The Epigenetic Evolution of Glioma Is Determined by the IDH1 Mutation Status and Treatment Regimen
Open the PDF for The Epigenetic Evolution of Glioma Is Determined by the IDH1 Mutation Status and Treatment Regimen in another window
Includes: Supplementary data
Journal Articles

Abstract LB061: Proteomic-based stemness score measure oncogenic dedifferentiation and enable the identification of druggable targets

Free
Tathiane M. Malta, Iga Kołodziejczak, Renan Simões, Antonio Colaprico, Erik Storrs, Francesca Petralia, Felipe da v Leprevost, Rossana L. Segura, Elizabeth Demicco, Alexander J. Lazar, Weiping Ma, Pietro Pugliese, Michele Ceccarelli, Bozena Kamińska, Alexey I. Nesvizhski, Bing Zhang, Henry Rodriguez, Mehdi Mesri, Ana I. Robles, Clinical Proteomic Tumor Analysis Consortium, Li Ding, Maciej Wiznerowicz
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): LB061.
https://doi.org/10.1158/1538-7445.AM2023-LB061
Published: 14 April 2023
View articletitled, Abstract LB061: Proteomic-based stemness score measure oncogenic dedifferentiation and enable the identification of druggable targets
Journal Articles

Abstract 6563: Glioma stem cell index recapitulates grade, IDH mutation status and correlates with survival of glioma patients

Free
Renan L. Simões, Maycon Marção, Tathiane M. Malta
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6563.
https://doi.org/10.1158/1538-7445.AM2023-6563
Published: 04 April 2023
View articletitled, Abstract 6563: Glioma stem cell index recapitulates grade, IDH mutation status and correlates with survival of glioma patients
Journal Articles

Abstract 2168: Longitudinal analysis of diffuse glioma reveals cell state dynamics at recurrence associated with changes in genetics and the microenvironment

Free
Frederick S. Varn, Kevin C. Johnson, Jan Martinek, Jason T. Huse, MacLean P. Nasrallah, Pieter Wesseling, Lee A. Cooper, Tathiane M. Malta, Taylor E. Wade, Thais S. Sabedot, Daniel J. Brat, Peter V. Gould, Adelheid Wöehrer, Kenneth Aldape, Azzam Ismail, Floris P. Barthel, Hoon Kim, Emre Kocakavuk, Nazia Ahmed, Kieron White, Santhosh Sivajothi, Indrani Datta, Jill S. Barnholtz-Sloan, Spyridon Bakas, Fulvio D'Angelo, Hui K. Gan, Luciano Garofano, Mustafa Khasraw, Simona Migliozzi, D. Ryan Ormond, Sun Ha Paek, Erwin G. Van Meir, Annemiek M. Walenkamp, Colin Watts, Michael Weller, Tobias Weiss, Karolina Palucka, Lucy F. Stead, Laila M. Poisson, Houtan Noushmehr, Antonio Iavarone, Roel G. Verhaak, The GLASS Consortium
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2168.
https://doi.org/10.1158/1538-7445.AM2022-2168
Published: 15 June 2022
View articletitled, Abstract 2168: Longitudinal analysis of diffuse glioma reveals cell state dynamics at recurrence associated with changes in genetics and the microenvironment
Journal Articles

Abstract 781: Methylation-based liquid biopsy of meningioma primary and recurrent samples

Free
Thais S. Sabedot, Tathiane M. Malta, Ruicong She, James Snyder, Tobias Walbert, Ian Lee, Steven Kalkanis, James Ewing, AnaValeria Castro, Houtan Noushmehr
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 781.
https://doi.org/10.1158/1538-7445.AM2020-781
Published: 15 August 2020
View articletitled, Abstract 781: Methylation-based liquid biopsy of meningioma primary and recurrent samples
Journal Articles

Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGFβ Signaling

Free
Jian Chen, Abhisek Mitra, Shulin Li, Shumei Song, Bao-Ngoc Nguyen, Jiun-Sheng Chen, Ji-Hyun Shin, Nancy R. Gough, Paul Lin, Vincent Obias, Aiwu Ruth He, Zhixing Yao, Tathiane M. Malta, Houtan Noushmehr, Patricia S. Latham, Xiaoping Su, Asif Rashid, Bibhuti Mishra, Ray-Chang Wu, Lopa Mishra
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (9): 1819–1832.
https://doi.org/10.1158/0008-5472.CAN-19-3116
Published: 04 May 2020
View articletitled, Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGFβ Signaling
Open the PDF for Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGFβ Signaling in another window
Includes: Supplementary data
Journal Articles

Abstract 841: Meningioma subgroups associated with functional genomic elements defined by DNA methylation

Free
Tathiane M. Malta, James Snyder, Michael Wells, Ana deCarvalho, Laila Poisson, Camila Souza, Gelareh Zadeh, Kenneth Aldape, Daniela Tirapelli, Carlos Carlotti, Yan Lee, Steven Kalkanis, Tobias Walbert, Houtan Noushmehr
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 841.
https://doi.org/10.1158/1538-7445.AM2019-841
Published: 01 July 2019
View articletitled, Abstract 841: Meningioma subgroups associated with functional genomic elements defined by DNA methylation
Journal Articles

Abstract LB-234: Pre-surgical identification of diagnostic, prognostic and predictive DNA methylation-based markers in serum (liquid biopsy) of patients harboring gliomas

Free
Houtan Noushmehr, Thais S. Sabedot, Tathiane M. Malta, Kevin K. Nelson, James Snyder, Michael Wells, Maritza S. Mosella, Ana C. deCarvalho, Karam Asmaro, Lisa Scarpace, Adam M. Robin, Mark L. Rosenblum, Tom Mikkelsen, Jack Rock, Tobias Walbert, Ian Lee, Laila M. Poisson, Steven N. Kalkanis, Ana V. Castro
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-234.
https://doi.org/10.1158/1538-7445.AM2019-LB-234
Published: 01 July 2019
View articletitled, Abstract LB-234: Pre-surgical identification of diagnostic, prognostic and predictive DNA methylation-based markers in serum (liquid biopsy) of patients harboring gliomas
Journal Articles

Abstract LB-373: Comprehensive analysis of cancer stemness

Free
Tathiane M. Malta, Artem Sokolov, Andrew J. Gentles, Tomasz Burzykowski, Laila Poisson, John Weinstein, Bożena Kamińska, Joerg Huelsken, Larsson Omberg, Olivier Gevaert, Antonio Colaprico, Patrycja Czerwińska, Sylwia Mazurek, Lopa Mishra, Holger Heyn, Alex Krasnitz, Andrew K. Godwin, Alexander J. Lazar, The Cancer Genome Atlas Research Network, Joshua M. Stuart, Katherine Hoadley, Peter W. Laird, Houtan Noushmehr, Maciej Wiznerowicz
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-373.
https://doi.org/10.1158/1538-7445.AM2018-LB-373
Published: 01 July 2018
View articletitled, Abstract LB-373: Comprehensive analysis of cancer stemness