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Journal Articles

Abstract 2232: Association between sleep characteristics and cancer survival: Findings from the UK Biobank study

Jiajing Che, Jiali Lv, Keyu Pan, Tiantian Sun, Chao Cao, Shengxu Li, Tao Zhang, Fuzhong Xue, Lin Yang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2232.
https://doi.org/10.1158/1538-7445.AM2024-2232
Published: 22 March 2024
View article titled, Abstract 2232: Association between sleep characteristics and cancer survival: Findings from the UK Biobank study
Journal Articles

Abstract 7461: Obesity promotes breast cancer progression via complement 1q

Tao Zhang, Shimeng Liu, Myles Brown
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7461.
https://doi.org/10.1158/1538-7445.AM2024-7461
Published: 22 March 2024
View article titled, Abstract 7461: Obesity promotes breast cancer progression via complement 1q
Journal Articles

Abstract 3827: Optimizing the treatment schedule of radiotherapy combined with VEGFR-TKIs and PD-(L) 1 inhibitors in metastatic colorectal cancer

Zhenyu Lin, Menglan Zhai, Tao Zhang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3827.
https://doi.org/10.1158/1538-7445.AM2024-3827
Published: 22 March 2024
View article titled, Abstract 3827: Optimizing the treatment schedule of radiotherapy combined with VEGFR-TKIs and PD-(L) 1 inhibitors in metastatic colorectal cancer
Journal Articles

Osimertinib Covalently Binds to CD34 and Eliminates Myeloid Leukemia Stem/Progenitor Cells

Li Xia, Jie-Yang Liu, Meng-Ying Yang, Xue-Hong Zhang, Yue Jiang, Qian-Qian Yin, Chen-Hui Luo, Hong-Chen Liu, Zhi-Jie Kang, Cheng-Tao Zhang, Bei-Bei Gao, Ai-Wu Zhou, Hai-Yan Cai, Edmund K. Waller, Jin-Song Yan, Ying Lu
Journal: Cancer Research
Cancer Res (2024) 84 (3): 479–492.
https://doi.org/10.1158/0008-5472.CAN-23-1632
Published: 01 February 2024
View article titled, Osimertinib Covalently Binds to CD34 and Eliminates Myeloid Leukemia Stem/Progenitor Cells
Open the PDF for Osimertinib Covalently Binds to CD34 and Eliminates Myeloid Leukemia Stem/Progenitor Cells in another window
Includes: Supplementary data
Journal Articles

Abstract LB302: Radiotherapy exposure and baseline gut microbiota predict clinical outcomes of fruquintinib plus sintilimab in microsatellite-stable metastatic colorectal cancer

Min Jin, Mingxia Cheng, Shengli Yang, Lei Zhao, Dandan Yu, Zhenyu Lin, Pindong Li, Jing Wang, Jun Xue, Hong Ma, Jianli Hu, Tao Zhang, Hongli Liu
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): LB302.
https://doi.org/10.1158/1538-7445.AM2023-LB302
Published: 14 April 2023
View article titled, Abstract LB302: Radiotherapy exposure and baseline gut microbiota predict clinical outcomes of fruquintinib plus sintilimab in microsatellite-stable metastatic colorectal cancer
Journal Articles

Abstract LB202: Obesity-trained C1q+ macrophages compromiseT cell anti-tumor immunity

Tao Zhang, Shimeng Liu, Myles Brown
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): LB202.
https://doi.org/10.1158/1538-7445.AM2023-LB202
Published: 14 April 2023
View article titled, Abstract LB202: Obesity-trained C1q<sup>+</sup> macrophages compromiseT cell anti-tumor immunity
Journal Articles

Abstract 5400: Predicting disease progression in inoperable localized NSCLC patients using cfDNA fragmentomics assay

Yin Yang, Tao Zhang, Jingbo Wang, Jianyang Wang, Wanxiangfu Tang, Hua Bao, Haimeng Tang, Xue Wu, Yang Shao, Xin Wang, Yuqi Wu, Linfang Wu, Xin Xu, Kunpeng Xu, Jingjing Zhao, Luhua Wang, Nan Bi
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5400.
https://doi.org/10.1158/1538-7445.AM2023-5400
Published: 04 April 2023
View article titled, Abstract 5400: Predicting disease progression in inoperable localized NSCLC patients using cfDNA fragmentomics assay
Journal Articles

Abstract PD8-08: Pyrotinib in combination with trastuzumab and docetaxel as neoadjuvant treatment for HER2-positive early or locally advanced breast cancer (PHEDRA): A randomized, double-blind, multicenter, phase 3 study

Jiong Wu, Zhenzhen Liu, Hongjian Yang, Jinhai Tang, Kun Wang, Yunjiang Liu, Haibo Wang, Peifen Fu, Shuqun Zhang, Qiang Liu, Zefei Jiang, Shusen Wang, Jian Huang, Chuan Wang, Shu Wang, Yongsheng Wang, Linlin Zhen, Xiaoyu Zhu, Fei Wu, Tao Zhang, Jianjun Zou
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): PD8-08.
https://doi.org/10.1158/1538-7445.SABCS21-PD8-08
Published: 15 February 2022
View article titled, Abstract PD8-08: Pyrotinib in combination with trastuzumab and docetaxel as neoadjuvant treatment for HER2-positive early or locally advanced breast cancer (PHEDRA): A randomized, double-blind, multicenter, phase 3 study
Journal Articles

Cell-Cycle–Dependent Phosphorylation of PRPS1 Fuels Nucleotide Synthesis and Promotes Tumorigenesis

Xiaoqian Jing, Xiong-jun Wang, Tao Zhang, Wencheng Zhu, Yi Fang, Haoxuan Wu, Xinyu Liu, Ding Ma, Xiaopin Ji, Yimei Jiang, Kun Liu, Xianze Chen, Yi Shi, Yaqi Zhang, Minmin Shi, Weihua Qiu, Ren Zhao
Journal: Cancer Research
Cancer Res (2019) 79 (18): 4650–4664.
https://doi.org/10.1158/0008-5472.CAN-18-2486
Published: 13 September 2019
View article titled, Cell-Cycle–Dependent Phosphorylation of PRPS1 Fuels Nucleotide Synthesis and Promotes Tumorigenesis
Open the PDF for Cell-Cycle–Dependent Phosphorylation of PRPS1 Fuels Nucleotide Synthesis and Promotes Tumorigenesis in another window
Includes: Supplementary data
Journal Articles

Abstract 2210: Discovery of a novel third generation EGFR TKI and identification of its potential mechanism of resistance

Tao Zhang, Rong Qu, Chengbin Chen, Linjiang Tong, Fang Feng, Yi Chen, Meiyu Geng, Ke Ding, Hua Xie, Jian Ding
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2210.
https://doi.org/10.1158/1538-7445.AM2019-2210
Published: 01 July 2019
View article titled, Abstract 2210: Discovery of a novel third generation EGFR TKI and identification of its potential mechanism of resistance
Journal Articles

Abstract 4981: HER2-targeted antibody drug conjugates (ADCs) induce host immunity against cancer stem cells and are enhanced by anti-PD-L1

Leiming Xia, Lu Wen, Gang Wu, Tao Zhang, Frank Comer, Mary Jane Masson Hinrichs, Michael Oberst, Steven R. Coats, Alfred E. Chang, Yuanyuan Liu, Yangyi Bao, Max Wicha, Qiao Li
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4981.
https://doi.org/10.1158/1538-7445.AM2019-4981
Published: 01 July 2019
View article titled, Abstract 4981: HER2-targeted antibody drug conjugates (ADCs) induce host immunity against cancer stem cells and are enhanced by anti-PD-L1
Journal Articles

Abstract 1136: Decrease in maturation of stem cells along the neuroendocrine lineage contributes to stem cell overpopulation that drives human CRC development

Bruce M. Boman, Tao Zhang, Shirin Modarai, Lynn Opdenacker, Fields Jeremy
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1136.
https://doi.org/10.1158/1538-7445.AM2018-1136
Published: 01 July 2018
View article titled, Abstract 1136: Decrease in maturation of stem cells along the neuroendocrine lineage contributes to stem cell overpopulation that drives human CRC development
Journal Articles

Abstract 4857: Discovery of PF-06855800, a SAM competitive PRMT5 inhibitor with potent antitumor activity

Indrawan J. Mcalpine, John Tatlock, Joseph Billitti, John Braganza, Alexei Brooun, Deng Ya-Li, Brad Hirakawa, Kristen Jensen-Pergakes, Robert Kumpf, Wei Liu, Karen Maegley, Michele McTigue, Ryan Patman, Eugene Rui, Stephanie Scales, Noah Spiegel, Michelle Tran-Dubé, Fen Wang, Zhenxiong Wang, Shinji Yamazaki, Tao Zhang, Martin Wythes
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4857.
https://doi.org/10.1158/1538-7445.AM2018-4857
Published: 01 July 2018
View article titled, Abstract 4857: Discovery of PF-06855800, a SAM competitive PRMT5 inhibitor with potent antitumor activity
Journal Articles

An miRNA Expression Signature for the Human Colonic Stem Cell Niche Distinguishes Malignant from Normal Epithelia

Vignesh Viswanathan, Shirish Damle, Tao Zhang, Lynn Opdenaker, Shirin Modarai, Monica Accerbi, Skye Schmidt, Pamela Green, Deni Galileo, Juan Palazzo, Jeremy Fields, Sepehr Haghighat, Isidore Rigoutsos, Greg Gonye, Bruce M. Boman
Journal: Cancer Research
Cancer Res (2017) 77 (14): 3778–3790.
https://doi.org/10.1158/0008-5472.CAN-16-2388
Published: 13 July 2017
View article titled, An miRNA Expression Signature for the Human Colonic Stem Cell Niche Distinguishes Malignant from Normal Epithelia
Open the PDF for An miRNA Expression Signature for the Human Colonic Stem Cell Niche Distinguishes Malignant from Normal Epithelia in another window
Includes: Supplementary data
Journal Articles

miRNA-128 Suppresses Prostate Cancer by Inhibiting BMI-1 to Inhibit Tumor-Initiating Cells

Min Jin, Tao Zhang, Can Liu, Mark A. Badeaux, Bigang Liu, Ruifang Liu, Collene Jeter, Xin Chen, Alexander V. Vlassov, Dean G. Tang
Journal: Cancer Research
Series: Author Choice
Cancer Res (2014) 74 (15): 4183–4195.
https://doi.org/10.1158/0008-5472.CAN-14-0404
Published: 31 July 2014
View article titled, miRNA-128 Suppresses Prostate Cancer by Inhibiting BMI-1 to Inhibit Tumor-Initiating Cells
Open the PDF for miRNA-128 Suppresses Prostate Cancer by Inhibiting BMI-1 to Inhibit Tumor-Initiating Cells in another window
Includes: Supplementary data
Journal Articles

FGFR4 Promotes Stroma-Induced Epithelial-to-Mesenchymal Transition in Colorectal Cancer

Rui Liu, Jingyi Li, Ke Xie, Tao Zhang, Yunlong Lei, Yi Chen, Lu Zhang, Kai Huang, Kui Wang, Hong Wu, Min Wu, Edouard C. Nice, Canhua Huang, Yuquan Wei
Journal: Cancer Research
Cancer Res (2013) 73 (19): 5926–5935.
https://doi.org/10.1158/0008-5472.CAN-12-4718
Published: 01 October 2013
View article titled, FGFR4 Promotes Stroma-Induced Epithelial-to-Mesenchymal Transition in Colorectal Cancer
Open the PDF for FGFR4 Promotes Stroma-Induced Epithelial-to-Mesenchymal Transition in Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 2353: Novel inhibitors of PIM-1, PIM-2, and PIM-3 protein kinases: medicinal chemistry leading to AZD1208.

Michelle L. Lamb, Les A. Dakin, Michael H. Block, Huawei Chen, Erin Code, James E. Dowling, Xiaomei Feng, Andrew D. Ferguson, Isabelle Green, Alexander W. Hird, Tina Howard, Dennis Huszar, Erika K. Keeton, Paul D. Lyne, Hannah Pollard, Michael Rooney, Jon Read, Allan J. Wu, Tao Zhang, Xiaolan Zheng
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2353.
https://doi.org/10.1158/1538-7445.AM2013-2353
Published: 15 April 2013
View article titled, Abstract 2353: Novel inhibitors of PIM-1, PIM-2, and PIM-3 protein kinases: medicinal chemistry leading to AZD1208.
Journal Articles

Abstract 4924: Dysregulated transcriptional mechanisms that control crypt cell maturation: A mechanism that contributes to stem cell overpopulation during colon cancer development

Jayasree Padmanabhan, Greg Gonye, Tao Zhang, Bruce M. Boman
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4924.
https://doi.org/10.1158/1538-7445.AM2012-4924
Published: 15 April 2012
View article titled, Abstract 4924: Dysregulated transcriptional mechanisms that control crypt cell maturation: A mechanism that contributes to stem cell overpopulation during colon cancer development
Journal Articles

Abstract 5195: Progressive overpopulation of colonic stem cells during tumorigenesis is linked to delayed licensing of cells for DNA synthesis in the process of crypt cell maturation

Bruce M. Boman, Tao Zhang, Zenobia Cofer, Juan Palazzo, Jeremy Z. Fields
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5195.
https://doi.org/10.1158/1538-7445.AM2011-5195
Published: 15 April 2011
View article titled, Abstract 5195: Progressive overpopulation of colonic stem cells during tumorigenesis is linked to delayed licensing of cells for DNA synthesis in the process of crypt cell maturation
Journal Articles

Abstract 2672: Characterization of Hsp90/Cdc37 interaction and their critical residues using luciferase fragment complementation imaging

Yiqun Jiang, Denzil Bernard, Yanke Yu, Tao Zhang, Yanyan LI, Xueqi Fu, Shaomeng Wang, Duxin Sun
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2672.
https://doi.org/10.1158/1538-7445.AM10-2672
Published: 15 April 2010
View article titled, Abstract 2672: Characterization of Hsp90/Cdc37 interaction and their critical residues using luciferase fragment complementation imaging