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Journal Articles

Targeting BCL6 in gastrointestinal stromal tumor promotes p53-mediated apoptosis to enhance the antitumor activity of imatinib

Xiangyu Zeng, Fei Zhao, Jie Jia, Xianxiong Ma, Qi Jiang, Ruizhi Zhang, Chengguo Li, Tao Wang, Weizhen Liu, Yalan Hao, Kaixiong Tao, Zhenkun Lou, Peng Zhang
Journal: Cancer Research
Cancer Res CAN-23-0082.
https://doi.org/10.1158/0008-5472.CAN-23-0082
Published: 09 August 2023
View article titled, Targeting BCL6 in gastrointestinal stromal tumor promotes p53-mediated apoptosis to enhance the antitumor activity of imatinib
Open the PDF for Targeting BCL6 in gastrointestinal stromal tumor promotes p53-mediated apoptosis to enhance the antitumor activity of imatinib in another window
Includes: Supplementary data
Journal Articles

Abstract 5067: Inhibition of CD47-SIRPα axis to enhance immunity against different molecular subtypes of breast cancer

Xingru Ma, Zachary Hartman, Li-Chung Tsao, Tao Wang, Cong-Xiao Liu, Xiao Yang, Gangjun Lei, Junping Wei
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5067.
https://doi.org/10.1158/1538-7445.AM2023-5067
Published: 04 April 2023
View article titled, Abstract 5067: Inhibition of CD47-SIRPα axis to enhance immunity against different molecular subtypes of breast cancer
Journal Articles

Abstract 93: An endogenous molecular brake preventing APOBEC-driven tumor mutational burden, heterogeneity and therapy resistance

Ping Mu, Xiaoling Li, Yunguan Wang, Tao Wang, Su Deng
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 93.
https://doi.org/10.1158/1538-7445.AM2023-93
Published: 04 April 2023
View article titled, Abstract 93: An endogenous molecular brake preventing APOBEC-driven tumor mutational burden, heterogeneity and therapy resistance
Journal Articles

Abstract 696: Sensitizing breast cancers to immune checkpoint inhibitors through CD27 agonism and vaccination against tumor-associated antigen

Bin-Jin Hwang, Erika Crosby, Timothy Trotter, Li-Chung Tsao, Tao Wang, Xiao Yang, Herbert Kim Lyerly, Zachary Hartman
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 696.
https://doi.org/10.1158/1538-7445.AM2023-696
Published: 04 April 2023
View article titled, Abstract 696: Sensitizing breast cancers to immune checkpoint inhibitors through CD27 agonism and vaccination against tumor-associated antigen
Journal Articles

Abstract 683: Vaccination against androgen receptor splice variant induces anti-tumor adaptive immune responses

Robert D. Marek, Junping Wei, Tao Wang, Xiao-Yi Yang, Gangjun Lei, Zachary C. Hartman
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 683.
https://doi.org/10.1158/1538-7445.AM2023-683
Published: 04 April 2023
View article titled, Abstract 683: Vaccination against androgen receptor splice variant induces anti-tumor adaptive immune responses
Journal Articles

Abstract P2-23-01: Patient-derived xenografts allow deconvolution of single agent and combination chemotherapy responses in triple-negative breast cancer

Jonathan T. Lei, Chen Huang, Ramakrishnan R. Srinivasan, Suhas Vasaikar, Lacey E. Dobrolecki, Alaina N. Lewis, Na Zhao, Jin Cao, Susan G. Hilsenbeck, C. Kent Osborne, Mothaffar Rimawi, Matthew J. Ellis, Varduhi Petrosyan, Alexander B. Saltzman, Anna Malovannaya, John D. Landua, Bo Wen, Antrix Jain, Gerburg M. Wulf, Shunqiang Li, Daniel C. Kraushaar, Tao Wang, Xi Chen, Gloria V. Echeverria, Meenakshi Anurag, Bing Zhang, Michael T. Lewis
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P2-23-01.
https://doi.org/10.1158/1538-7445.SABCS22-P2-23-01
Published: 01 March 2023
View article titled, Abstract P2-23-01: Patient-derived xenografts allow deconvolution of single agent and combination chemotherapy responses in triple-negative breast cancer
Journal Articles

Abstract P5-02-12: Prognostic relevance of PD-L1 expression on circulating tumor cells in metastatic breast cancer patients treated with anti-PD-1 immunotherapy

Ying Zhou, Jinmei Zhou, Haoyuan Shi, Zhiyuan Hu, Yanlian Yang, Zefei Jiang, Tao Wang
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P5-02-12.
https://doi.org/10.1158/1538-7445.SABCS22-P5-02-12
Published: 01 March 2023
View article titled, Abstract P5-02-12: Prognostic relevance of PD-L1 expression on circulating tumor cells in metastatic breast cancer patients treated with anti-PD-1 immunotherapy
Journal Articles

Abstract P3-06-04: Treatment of Metastatic Breast Cancer with Multipotent Oncolytic/Helper Adenovirus CAdVEC

Natalie Chen, Daniel Wang, Caroline E. Porter, Amanda Rosewell Shaw, Catherine R. Robertson, Mae L. Woods, Ya Xu, Greyson Biegert, Alphi Kuriakose, Tao Wang, Bambi J. Grilley, Helen Heslop, Malcolm K. Brenner, Masataka Suzuki, Bora Lim
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P3-06-04.
https://doi.org/10.1158/1538-7445.SABCS22-P3-06-04
Published: 01 March 2023
View article titled, Abstract P3-06-04: Treatment of Metastatic Breast Cancer with Multipotent Oncolytic/Helper Adenovirus CAdVEC
Journal Articles

Abstract P6-11-14: Mitochondrial structure and function adaptation in residual triple negative breast cancer cells surviving chemotherapy treatment

Lily Baek, Junegoo Lee, Katherine E. Pendleton, Mariah J. Berner, Emily Goff, Lin Tan, Sara Martinez, Iqbal Mahmud, Argenis Arriojas, Alexander Zhurkevich, Tao Wang, Matthew Meyer, Bora Lim, James P. Barrish, Weston Porter, Kourosh Zarringhalam, Philip L. Lorenzi, Gloria V. Echeverria
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P6-11-14.
https://doi.org/10.1158/1538-7445.SABCS22-P6-11-14
Published: 01 March 2023
View article titled, Abstract P6-11-14: Mitochondrial structure and function adaptation in residual triple negative breast cancer cells surviving chemotherapy treatment
Journal Articles

Abstract PR015: Dormant mammary tumors persist long-term despite adaptive immunity by establishing a Treg-dominated niche via DKK3

Timothy N. Trotter, Delila Serra, Carina Dagotto, Tao Wang, Xiao Yang, Junping Wei, Gangjun Lei, H. Kim Lyerly, Zachary C. Hartman
Journal: Cancer Research
Cancer Res (2023) 83 (2_Supplement_2): PR015.
https://doi.org/10.1158/1538-7445.METASTASIS22-PR015
Published: 15 January 2023
View article titled, Abstract PR015: Dormant mammary tumors persist long-term despite adaptive immunity by establishing a Treg-dominated niche via DKK3
Journal Articles

Abstract 1208: Denoising spatial expression profiling data based on in situ position and image information

Yunguan Wang, Bing Song, Shidan Wang, Mengyi Chen, Yang Xie, Guanghua Xiao, Li Wang, Tao Wang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1208.
https://doi.org/10.1158/1538-7445.AM2022-1208
Published: 15 June 2022
View article titled, Abstract 1208: Denoising spatial expression profiling data based on in situ position and image information
Journal Articles

Abstract 2451: Dormant mammary tumors resist antigen-specific killing and regulate systemic immunity in association with PTN and DKK3

Timothy N. Trotter, Delila Serra, Carina Dagotto, Tao Wang, Xiao Yang, Junping Wei, Gangjun Lei, H. Kim Lyerly, Zachary C. Hartman
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2451.
https://doi.org/10.1158/1538-7445.AM2022-2451
Published: 15 June 2022
View article titled, Abstract 2451: Dormant mammary tumors resist antigen-specific killing and regulate systemic immunity in association with PTN and DKK3
Journal Articles

Abstract 3930: AI-driven discovery and profiling of GTAEXS-617, a selective and highly potent inhibitor of CDK7

Jérémy Besnard, James Joseph, Haiyun Bai, Ross A. Paveley, Tao Wang, Olivier R. Barbeau, Xiao-Hui Gu, Andrew S. Bell, Mate Somlyay, Christina Taubert, Christophe Boudesco, Gregory Vladimer, Fred Aswad
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3930.
https://doi.org/10.1158/1538-7445.AM2022-3930
Published: 15 June 2022
View article titled, Abstract 3930: AI-driven discovery and profiling of GTAEXS-617, a selective and highly potent inhibitor of CDK7
Journal Articles

Abstract 3531: Sensitizing immune unresponsive colorectal cancers to immune checkpoint inhibitors through MAVS overexpression

Bin-Jin Hwang, Li-Chung Tsao, Chaitanya Acharya, Timothy Trotter, Pankaj Agarwal, Tao Wang, Junping Wei, Xiao-Yi Yang, Gang-jun Lei, Takuya Osada, Herbert Kim Lyerly, Michael A. Morse, Zachary Hartman
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3531.
https://doi.org/10.1158/1538-7445.AM2022-3531
Published: 15 June 2022
View article titled, Abstract 3531: Sensitizing immune unresponsive colorectal cancers to immune checkpoint inhibitors through MAVS overexpression
Journal Articles

Abstract 3564: Vaccination using different platforms encoding HER2-LAMP with heterologous boosting enhances adaptive HER2-specific immunity to enable potent anti-tumor responses

Robert D. Marek, Alan Chen, Renhuan Xu, Junping Wei, Tao Wang, Xiao Yang, Gangjun Lei, Teri Heiland, Zachary C. Hartman
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3564.
https://doi.org/10.1158/1538-7445.AM2022-3564
Published: 15 June 2022
View article titled, Abstract 3564: Vaccination using different platforms encoding HER2-LAMP with heterologous boosting enhances adaptive HER2-specific immunity to enable potent anti-tumor responses
Journal Articles

Abstract PD8-05: Overall survival (OS) results from the phase III PHENIX trial of HER2+ metastatic breast cancer treated with pyrotinib plus capecitabine

Zefei Jiang, Min Yan, Li Bian, Tao Wang, Xichun Hu, Qingyuan Zhang, Quchang Ouyang, Jifeng Feng, Yongmei Yin, Tao Sun, Zhongsheng Tong, Xiaojia Wang, Herui Yao, Shuping Jiang, Xiaoyu Zhu, Jianjun Zou
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): PD8-05.
https://doi.org/10.1158/1538-7445.SABCS21-PD8-05
Published: 15 February 2022
View article titled, Abstract PD8-05: Overall survival (OS) results from the phase III PHENIX trial of HER2+ metastatic breast cancer treated with pyrotinib plus capecitabine
Journal Articles

Abstract P1-21-04: The real word study on clinical features and prognostic factors of Chinese breast cancer patients with brain metastasis

Tao Wang, Huiqiang Zhang, Feng Li, Xia Wu, Jinmei Zhou, Shao hua Zhang, Li Bian, Ze fei Jiang
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-21-04.
https://doi.org/10.1158/1538-7445.SABCS21-P1-21-04
Published: 15 February 2022
View article titled, Abstract P1-21-04: The real word study on clinical features and prognostic factors of Chinese breast cancer patients with brain metastasis
Journal Articles

Abstract P5-07-01: Proteogenomic analysis of differential chemotherapy responses in patient-derived xenografts of triple-negative breast cancer

Jonathan T Lei, Chen Huang, Ramakrishnan R Srinivasan, Suhas Vasaikar, Lacey E Dobrolecki, Alaina N Lewis, Christina Sallas, Susan G Hilsenbeck, C. Kent Osborne, Mothaffar F Rimawi, Matthew J Ellis, Varduhi Petrosyan, Alexander B Saltzman, Anna Malovannaya, Gerburg Wulf, Daniel C Kraushaar, Tao Wang, Xi Chen, Gloria V Echeverria, Meenakshi Anurag, Bing Zhang, Michael T Lewis
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P5-07-01.
https://doi.org/10.1158/1538-7445.SABCS21-P5-07-01
Published: 15 February 2022
View article titled, Abstract P5-07-01: Proteogenomic analysis of differential chemotherapy responses in patient-derived xenografts of triple-negative breast cancer
Journal Articles

Abstract PD2-01: A platform of CDK4/6 inhibitor-resistant patient-derived breast cancer organoids illuminates mechanisms of resistance and therapeutic vulnerabilities

Ariella B. Hanker, Sumanta Chatterjee, Yunguan Wang, Dan Ye, Dhivya R. Sudhan, Brian M. Larsen, Lauren C. Smith, Yilin Zhang, Vishal Kandagatla, Kuntal Majmudar, Ezequiel Renzulli, Saurabh Mendiratta, Kimberly Blackwell, Alana L. Welm, Sunati Sahoo, Nisha Unni, Cheryl M. Lewis, Tao Wang, Ameen A. Salahudeen, Carlos L. Arteaga
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): PD2-01.
https://doi.org/10.1158/1538-7445.SABCS21-PD2-01
Published: 15 February 2022
View article titled, Abstract PD2-01: A platform of CDK4/6 inhibitor-resistant patient-derived breast cancer organoids illuminates mechanisms of resistance and therapeutic vulnerabilities
Journal Articles

A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis

Fei Yue, Weiyu Jiang, Amy T. Ku, Adelaide I.J. Young, Weijie Zhang, Eric P. Souto, Yankun Gao, Zihan Yu, Yi Wang, Chad J. Creighton, Chandandeep Nagi, Tao Wang, Susan G. Hilsenbeck, Xin-Hua Feng, Shixia Huang, Cristian Coarfa, Xiang H.-F. Zhang, Qingyun Liu, Xia Lin, Yi Li
Journal: Cancer Research
Cancer Res (2021) 81 (17): 4441–4454.
https://doi.org/10.1158/0008-5472.CAN-21-1112
Published: 01 September 2021
View article titled, A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis
Open the PDF for A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis in another window
Includes: Supplementary data