1-20 of 28
Tanja D. de Gruijl
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract 2488: The penile cancer tumor microenvironment and immunotherapy response: Results from the PERICLES trial

Tynisha S. Rafael, Alberto Gil-Jimenez, Hielke M. de Vries, Iris M. Seignette, Elise Bekers, Marta Lopez-Yurda, Dennis Peters, Erik Hooijberg, Annegien Broeks, Oscar R. Brouwer, Eva Schaake, Daniel J. Vis, Tanja D. de Gruijl, Lodewyk F.A. Wessels, Michiel S. van der Heijden
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2488.
https://doi.org/10.1158/1538-7445.AM2024-2488
Published: 22 March 2024
View article titled, Abstract 2488: The penile cancer tumor microenvironment and immunotherapy response: Results from the PERICLES trial
Journal Articles

Abstract 1855: Potent anti-tumor activity against patient CLL, MM and AML by LAVA-051, a bispecific Vγ9Vδ2-T and type 1 NKT cell engager targeting CD1d

Roeland Lameris, Jurjen M. Ruben, Iris de Weerdt, Rob C. Roovers, Arnon P. Kater, Thilo A. Riedl, Victoria Iglesias, Ton Adang, Tanja D. de Gruijl, Paul W.H.I Parren, Hans J. van der Vliet
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1855.
https://doi.org/10.1158/1538-7445.AM2021-1855
Published: 01 July 2021
View article titled, Abstract 1855: Potent anti-tumor activity against patient CLL, MM and AML by LAVA-051, a bispecific Vγ9Vδ2-T and type 1 NKT cell engager targeting CD1d
Journal Articles

Abstract 1136: Tumor uptake and biodistribution of 89Zirconium-labeled ipilimumab in patients with metastatic melanoma during ipilimumab treatment

Iris H. Miedema, Gerben J. Zwezerijnen, Guus A. van Dongen, Daniëlle J. Vugts, Marc C. Huisman, Otto S. Hoekstra, Tanja D. de Gruijl, Hendrik M. Verheul, Catharina W. Menke, Alfons J. van den Eertwegh
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1136.
https://doi.org/10.1158/1538-7445.AM2019-1136
Published: 01 July 2019
View article titled, Abstract 1136: Tumor uptake and biodistribution of <sup>89</sup>Zirconium-labeled ipilimumab in patients with metastatic melanoma during ipilimumab treatment
Journal Articles

Abstract 4133: The in vitro melanoma tumor microenvironment conditions macrophages to an immunosuppressive M2-like phenotype, which is reversible by oncolytic virus ORCA-010 with immune modulators

Ioanna E. Milenova, Rieneke van de Ven, Wenliang Dong, Victor W. van Beusechem, Tanja D. de Gruijl
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4133.
https://doi.org/10.1158/1538-7445.AM2019-4133
Published: 01 July 2019
View article titled, Abstract 4133: The <em>in vitro</em> melanoma tumor microenvironment conditions macrophages to an immunosuppressive M2-like phenotype, which is reversible by oncolytic virus ORCA-010 with immune modulators
Journal Articles

Evaluation of Explant Responses to STING Ligands: Personalized Immunosurgical Therapy for Head and Neck Squamous Cell Carcinoma

Jason R. Baird, R. Bryan Bell, Victoria Troesch, David Friedman, Shelly Bambina, Gwen Kramer, Tiffany C. Blair, Terry Medler, Yaping Wu, Zhaoyu Sun, Tanja D. de Gruijl, Rieneke van de Ven, Rom S. Leidner, Marka R. Crittenden, Michael J. Gough
Journal: Cancer Research
Cancer Res (2018) 78 (21): 6308–6319.
https://doi.org/10.1158/0008-5472.CAN-18-1652
Published: 01 November 2018
View article titled, Evaluation of Explant Responses to STING Ligands: Personalized Immunosurgical Therapy for Head and Neck Squamous Cell Carcinoma
Open the PDF for Evaluation of Explant Responses to STING Ligands: Personalized Immunosurgical Therapy for Head and Neck Squamous Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 3877: MPL-5821, a macrophage targeted ESMTM p38 MAPK inhibitor, inhibits the production of TLR agonist induced IL-10 whilst sparing T-cell functionality

David Moffat, Martin Perry, A. Marijne Heeren, Tanja D. de Gruijl, Justyna Rzepecka, Lucia Janicova, Anastasia Nika, Darryl Turner, Clare Doris, Claire Tebbutt, Kathryn Chapman, Gary Newton, Stephen Anderton
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3877.
https://doi.org/10.1158/1538-7445.AM2018-3877
Published: 01 July 2018
View article titled, Abstract 3877: MPL-5821, a macrophage targeted ESM<sup>TM</sup> p38 MAPK inhibitor, inhibits the production of TLR agonist induced IL-10 whilst sparing T-cell functionality
Journal Articles

Abstract 4584: High PD-1 expression on regulatory and effector T cells in lung cancer draining lymph nodes

Rieneke Van De Ven, Anna-Larissa N. Niemeijer, Anita G. Stam, Sayed M. Hashemi, Christian G. Slockers, Johannes M. Daniels, Erik Thunnissen, Egbert F. Smit, Tanja D. de Gruijl, Adrianus J. de Langen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4584.
https://doi.org/10.1158/1538-7445.AM2017-4584
Published: 01 July 2017
View article titled, Abstract 4584: High PD-1 expression on regulatory and effector T cells in lung cancer draining lymph nodes
Journal Articles

Abstract 4692: Local adjuvant treatment of clinical stage I-II melanoma with low dose CpG-B and/or GM-CSF: Long-term follow-up of three randomized controlled phase II trials

Bas D. Koster, Mari F. van den Hout, Berbel J. Sluijter, Barbara G. Molenkamp, Ronald J. Vuylsteke, Arnold Baars, Paul A. van Leeuwen, Rik J. Scheper, Monique P. van den Tol, Alfons J. van den Eertwegh, Tanja D. de Gruijl
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4692.
https://doi.org/10.1158/1538-7445.AM2017-4692
Published: 01 July 2017
View article titled, Abstract 4692: Local adjuvant treatment of clinical stage I-II melanoma with low dose CpG-B and/or GM-CSF: Long-term follow-up of three randomized controlled phase II trials
Journal Articles

Abstract 2496: Preclinical testing of a novel anti-angiogenic vaccine targeting human VEGF

Madelon Q. Wentink, Peter Timmerman, Hans J. van der Vliet, Tanja D. de Gruijl, Henk M.W. Verheul, Arjan W. Griffioen
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2496.
https://doi.org/10.1158/1538-7445.AM2015-2496
Published: 01 August 2015
View article titled, Abstract 2496: Preclinical testing of a novel anti-angiogenic vaccine targeting human VEGF
Journal Articles

Abstract P5-04-01: Breast cancer related immune suppression in the sentinel lymph node can be effectively countered by combined CpG-B administration and JAK2/STAT3 inhibition

Kim M van Pul, Ronald JCLM Vuylsteke, Sinéad M Lougheed, Lisette EA te Velde, Petrousjka van den Tol, Emiel J Th Rutgers, Hein BAC Stockmann, Tanja D de Gruijl
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P5-04-01.
https://doi.org/10.1158/1538-7445.SABCS14-P5-04-01
Published: 01 May 2015
View article titled, Abstract P5-04-01: Breast cancer related immune suppression in the sentinel lymph node can be effectively countered by combined CpG-B administration and JAK2/STAT3 inhibition
Journal Articles

Abstract 908: Development of a cell proliferation assay to be used as a read-out system for determining the in vivo potency of bevacizumab in neutralizing the biological activity of VEGF in cancer patients

Madelon Q. Wentink, Henk J. Broxterman, Tanja D. de Gruijl, Roberto Pili, Hans J. van der Vliet, Arjan W. Griffioen, Henk M.W. Verheul
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 908.
https://doi.org/10.1158/1538-7445.AM2014-908
Published: 01 October 2014
View article titled, Abstract 908: Development of a cell proliferation assay to be used as a read-out system for determining the <em>in vivo</em> potency of bevacizumab in neutralizing the biological activity of VEGF in cancer patients
Journal Articles

Abstract 4720: mTOR inhibition is required for conversion of invariant NKT cells into immunosuppressive regulatory cells.

Charlotte M. Huijts, Famke L. Schneiders, Henk M. Verheul, Tanja D. de Gruijl, Hans J. van der Vliet
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4720.
https://doi.org/10.1158/1538-7445.AM2013-4720
Published: 15 April 2013
View article titled, Abstract 4720: mTOR inhibition is required for conversion of invariant NKT cells into immunosuppressive regulatory cells.
Journal Articles

Abstract 496: Inflammatory responses with infiltrating DC and functional cytotoxic T lymphocytes in the dermal vaccination sites of GVAX/ipilimumab treated prostate cancer patients.

Saskia J. Santegoets, Leonieke JJ van Mens, Jeroen AM Beliën, Anita GM Stam, Sinead M. Lougheed, Rik J. Scheper, Shabnam Samiei, Helen Gall, Karin Jooss, Jean-Marie Cuillerot, Natalie Sacks, Kirsten Hege, Winald R. Gerritsen, Alfons JM van den Eertwegh, Tanja D. de Gruijl
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 496.
https://doi.org/10.1158/1538-7445.AM2013-496
Published: 15 April 2013
View article titled, Abstract 496: Inflammatory responses with infiltrating DC and functional cytotoxic T lymphocytes in the dermal vaccination sites of GVAX/ipilimumab treated prostate cancer patients.
Journal Articles

Abstract 1229: Pre-existing NY-ESO-1-specific T cell reactivity is associated with improved clinical outcome in castration resistant prostate cancer patients treated with Prostate GVAX and ipilimumab.

Anita GM Stam, Saskia JAM Santegoets, Alfons JM van den Eertwegh, Rik J. Scheper, Sinéad M. Lougheed, Helen Gall, Karin Jooss, Natalie Sacks, Thomas Harding, Kristen Hege, Israel Lowy, Sacha Gnjatic, Jedd D. Wolchok, Winald R. Gerritsen, Tanja D. de Gruijl
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1229.
https://doi.org/10.1158/1538-7445.AM2013-1229
Published: 15 April 2013
View article titled, Abstract 1229: Pre-existing NY-ESO-1-specific T cell reactivity is associated with improved clinical outcome in castration resistant prostate cancer patients treated with Prostate GVAX and ipilimumab.
Journal Articles

Abstract 3533: Acquisition of antigen presenting cell functions by Vγ9Vα2-T cells requires trogocytosis

Famke L. Schneiders, Saskia J.A.M. Santegoets, Rik J. Scheper, Henk M.W. Verheul, Marc Bonneville, Emmanuel Scotet, Tanja D. de Gruijl, Hans J. van der Vliet
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3533.
https://doi.org/10.1158/1538-7445.AM2012-3533
Published: 15 April 2012
View article titled, Abstract 3533: Acquisition of antigen presenting cell functions by Vγ9Vα2-T cells requires trogocytosis
Journal Articles

Potent Antitumor Immunity Generated by a CD40-Targeted Adenoviral Vaccine

Basav N. Hangalapura, Dinja Oosterhoff, Jan de Groot, Louis Boon, Thomas Tüting, Alfons J. van den Eertwegh, Winald R. Gerritsen, Victor W. van Beusechem, Alexander Pereboev, David T. Curiel, Rik J. Scheper, Tanja D. de Gruijl
Journal: Cancer Research
Cancer Res (2011) 71 (17): 5827–5837.
https://doi.org/10.1158/0008-5472.CAN-11-0804
Published: 30 August 2011
View article titled, Potent Antitumor Immunity Generated by a CD40-Targeted Adenoviral Vaccine
Open the PDF for Potent Antitumor Immunity Generated by a CD40-Targeted Adenoviral Vaccine in another window
Includes: Supplementary data
Journal Articles

Abstract 5512: Immune correlates of clinical response and survival in castration-resistant prostate cancer patients treated with prostate GVAX and anti-CTLA4 immunotherapy

Saskia J.A.M. Santegoets, Alfons J.M. van den Eertwegh, Anita G.M. Stam, Rik J. Scheper, Sinéad M. Lougheed, Petra E.T. Scholten, Mary B.M.E. von Blomberg, Helen Gall, Karin Jooss, Minh C. Nguyen, Tom Harding, Natalie Sacks, Kristen Hege, Israel Lowy, Kevin Chin, Winald R. Gerritsen, Tanja D. de Gruijl
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5512.
https://doi.org/10.1158/1538-7445.AM2011-5512
Published: 15 April 2011
View article titled, Abstract 5512: Immune correlates of clinical response and survival in castration-resistant prostate cancer patients treated with prostate GVAX and anti-CTLA4 immunotherapy
Journal Articles

Abstract 2934: Increased type-2 T cell rates and coincidence of Th17 spikes with autoimmune events and PSA declines upon combined prostate GVAX and anti-CTLA4 immunotherapy

Anita GM Stam, Saskia JAM Santegoets, Rik J. Scheper, Sinead M. Lougheed, Helen Gall, Karin Jooss, Natalie Sacks, Kristen Hege, Israel Lowy, Winald R. Gerritsen, Alfons JM van den Eertwegh, Tanja D. de Gruijl
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2934.
https://doi.org/10.1158/1538-7445.AM10-2934
Published: 15 April 2010
View article titled, Abstract 2934: Increased type-2 T cell rates and coincidence of Th17 spikes with autoimmune events and PSA declines upon combined prostate GVAX and anti-CTLA4 immunotherapy
Journal Articles

Abstract 5588: T cell activation in relation to clinical responsiveness in patients with metastatic hormone-refractory prostate cancer receiving combined Prostate GVAX and anti-CTLA4 immunotherapy

Saskia J. Santegoets, Anita G. Stam, Rik J. Scheper, Petra E. Scholten, B M. von Blomberg, Helen Gall, Karin Jooss, Nathalie Sacks, Tom Harding, Kristen Hege, Israel Lowy, Alfons J. van den Eertwegh, Winald R. Gerritsen, Tanja D. de Gruijl
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5588.
https://doi.org/10.1158/1538-7445.AM10-5588
Published: 15 April 2010
View article titled, Abstract 5588: T cell activation in relation to clinical responsiveness in patients with metastatic hormone-refractory prostate cancer receiving combined Prostate GVAX and anti-CTLA4 immunotherapy
Journal Articles

Abstract 5618: Arming the melanoma sentinel lymph node against tumor spread: The effects of local administration of combined low-dose CpG-B PF-3512676 and GM-CSF

Mari F.c.m. van den Hout, Berbel J.r. Sluijter, Saskia J.a.m. Santegoets, Alfons J.m. van den Eertwegh, Sybren Meijer, Petrousjka van den Tol, Paul A.m. van Leeuwen, Rik J. Scheper, Tanja D. de Gruijl
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5618.
https://doi.org/10.1158/1538-7445.AM10-5618
Published: 15 April 2010
View article titled, Abstract 5618: Arming the melanoma sentinel lymph node against tumor spread: The effects of local administration of combined low-dose CpG-B PF-3512676 and GM-CSF