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Takashi Kojima
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Journal Articles

Abstract CT193: Final results from a phase I study to evaluate the safety and efficacy of a telomerase-specific oncolytic adenovirus (OBP-301) with pembrolizumab in patients with advanced solid tumors (EPOC1505)

Takashi Kojima, Toshiyoshi Fujiwara, Shunsuke Tanabe, Tomoyuki Kadota, Hiromi Ono, Kazuko Tsukamoto, Takashi Ikeno, Masashi Wakabayashi, Akihiro Sato, Masanori Kondo, Shogo Kumagai, Shohei Koyama, Hiroyoshi Nishikawa, Toshihiko Doi
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT193.
https://doi.org/10.1158/1538-7445.AM2023-CT193
Published: 14 April 2023
View article titled, Abstract CT193: Final results from a phase I study to evaluate the safety and efficacy of a telomerase-specific oncolytic adenovirus (OBP-301) with pembrolizumab in patients with advanced solid tumors (EPOC1505)
Journal Articles

Abstract CT024: Early safety from an open label Phase I study to evaluate the safety and efficacy of a telomerase-specific oncolytic adenovirus (OBP-301) with pembrolizumab in patients with advanced solid tumors. (EPOC1505)

Takashi Kojima, Toshiyoshi Fujiwara, Yasuhiro Shirakawa, Keisuke Hori, Hiromi Ono, Masako Nakamoto, Nami Hirano, Masashi Wakabayashi, Shogo Nomura, Yosuke Togashi, Hiroyoshi Nishikawa, Akihiro Sato, Atushi Ohtsu, Toshihiko Doi
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT024.
https://doi.org/10.1158/1538-7445.AM2019-CT024
Published: 01 July 2019
View article titled, Abstract CT024: Early safety from an open label Phase I study to evaluate the safety and efficacy of a telomerase-specific oncolytic adenovirus (OBP-301) with pembrolizumab in patients with advanced solid tumors. (EPOC1505)
Journal Articles

Abstract 2813: Clinical impact of immune microenvironment according to intratumoral locations of esophageal squamous cell carcinoma

Ken Hatogai, Satoshi Fujii, Takashi Kojima, Shigehisa Kitano, Hiroyuki Daiko, Takayuki Yoshino, Atsushi Ohtsu, Toshihiko Doi, Atsushi Ochicai
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2813.
https://doi.org/10.1158/1538-7445.AM2019-2813
Published: 01 July 2019
View article titled, Abstract 2813: Clinical impact of immune microenvironment according to intratumoral locations of esophageal squamous cell carcinoma
Journal Articles

Abstract 220: U3-1402, a novel HER3-targeting ADC, inhibits the tumor growth of colorectal cancer xenografts

Shigehiro Koganemaru, Yasutoshi Kuboki, Yoshikatsu Koga, Takashi Kojima, Mayumi Yamauchi, Naoyuki Maeda, Takashi Kagari, Kenji Hirotani, Masahiro Yasunaga, Yasuhiro Matsumura, Toshihiko Doi
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 220.
https://doi.org/10.1158/1538-7445.AM2019-220
Published: 01 July 2019
View article titled, Abstract 220: U3-1402, a novel HER3-targeting ADC, inhibits the tumor growth of colorectal cancer xenografts
Journal Articles

Abstract 2935: Preclinical efficacy of the p70S6K/AKT dual inhibitor M2698 in combination with trastuzumab in models of gastric cancer

Shota Fukuoka, Takashi Kojima, Yoshikatsu Koga, Mayumi Yamauchi, Masahiro Yasunaga, Yasuhiro Matsumura, Kohei Shitara, Toshihiko Doi, Takayuki Yoshino, Toshio Kuronita, Anderson Clark, Brian Elenbaas, Hong Zhang, Atsushi Ohtsu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2935.
https://doi.org/10.1158/1538-7445.AM2018-2935
Published: 01 July 2018
View article titled, Abstract 2935: Preclinical efficacy of the p70S6K/AKT dual inhibitor M2698 in combination with trastuzumab in models of gastric cancer
Journal Articles

Abstract 139: M2698, a novel dual inhibitor of p70S6K and Akt: preclinical efficacy in gastric cancer

Shota Fukuoka, Takashi Kojima, Yoshikatsu Koga, Mayumi Yamauchi, Masahiro Yasunaga, Yasuhiro Matsumura, Toshihiko Doi, Takayuki Yoshino, Toshio Kuronita, Anderson Clark, Brian Elenbaas, Atsuhi Ohtsu
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 139.
https://doi.org/10.1158/1538-7445.AM2017-139
Published: 01 July 2017
View article titled, Abstract 139: M2698, a novel dual inhibitor of p70S6K and Akt: preclinical efficacy in gastric cancer
Journal Articles

Abstract 1669: Preclinical efficacy of Sym004, novel anti-EGFR antibody, in esophageal squamous cell carcinoma cell lines

Shota Fukuoka, Takashi Kojima, Yoshikatsu Koga, Mayumi Yamauchi, Rie Komatsuzaki, Kazuhiko Aoyagi, Hiroki Sasaki, Masahiro Yasunaga, Yasuhiro Matsumura, Toshio Kuronita, Toshihiko Doi, Atsushi Ohtsu
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1669.
https://doi.org/10.1158/1538-7445.AM2015-1669
Published: 01 August 2015
View article titled, Abstract 1669: Preclinical efficacy of Sym004, novel anti-EGFR antibody, in esophageal squamous cell carcinoma cell lines
Journal Articles

Abstract 29: Phase I study of intravenous PI3K inhibitor BAY 80-6946 in Japanese subjects.

Toshihiko Doi, Nozomu Fuse, Takayuki Yoshino, Takashi Kojima, Hideaki Bando, Hideaki Miyamoto, Masato Kaneko, Motonobu Osada, Atsushi Ohtsu
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 29.
https://doi.org/10.1158/1538-7445.AM2013-29
Published: 15 April 2013
View article titled, Abstract 29: Phase I study of intravenous PI3K inhibitor BAY 80-6946 in Japanese subjects.
Journal Articles

Epigenetic Silencing of Occludin Promotes Tumorigenic and Metastatic Properties of Cancer Cells via Modulations of Unique Sets of Apoptosis-Associated Genes

Makoto Osanai, Masaki Murata, Nami Nishikiori, Hideki Chiba, Takashi Kojima, Norimasa Sawada
Journal: Cancer Research
Cancer Res (2006) 66 (18): 9125–9133.
https://doi.org/10.1158/0008-5472.CAN-06-1864
Published: 18 September 2006
View article titled, Epigenetic Silencing of Occludin Promotes Tumorigenic and Metastatic Properties of Cancer Cells via Modulations of Unique Sets of Apoptosis-Associated Genes
Open the PDF for Epigenetic Silencing of Occludin Promotes Tumorigenic and Metastatic Properties of Cancer Cells via Modulations of Unique Sets of Apoptosis-Associated Genes in another window
Journal Articles

Epigenetic Inactivation of CHFR and Sensitivity to Microtubule Inhibitors in Gastric Cancer

Ayumi Satoh, Minoru Toyota, Fumio Itoh, Yasushi Sasaki, Hiromu Suzuki, Kazuhiro Ogi, Takefumi Kikuchi, Hiroaki Mita, Toshiharu Yamashita, Takashi Kojima, Masanobu Kusano, Masahiro Fujita, Masao Hosokawa, Takao Endo, Takashi Tokino, Kohzoh Imai
Journal: Cancer Research
Cancer Res (2003) 63 (24): 8606–8613.
Published: 24 December 2003
View article titled, Epigenetic Inactivation of CHFR and Sensitivity to Microtubule Inhibitors in Gastric Cancer
Open the PDF for Epigenetic Inactivation of CHFR and Sensitivity to Microtubule Inhibitors in Gastric Cancer in another window