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Journal Articles

Abstract 5355: Whole genome landscape of small cell lung carcinoma and large cell neuroendocrine carcinoma of the lung

Hisashi Hashimoto, Yosuke Tanaka, Jun Takahashi, Toshihide Ueno, Shinya Kojima, Kouya Shiraishi, Takashi Kohno, Yuichi Shiraishi, Yasushi Yatabe, Takeshi Kaneko, Hiroyuki Mano

Cancer Res (2025) 85 (8_Supplement_1): 5355.

https://doi.org/10.1158/1538-7445.AM2025-5355

Published: 21 April 2025

View articletitled, Abstract 5355: Whole genome landscape of small cell lung carcinoma and large cell neuroendocrine carcinoma of the lung

Journal Articles

Abstract 5146: Clinical significance of inter-assay discrepancy in PD-L1 expression evaluation for the efficacy of pembrolizumab in advanced NSCLC patients with high PD-L1 expression

Jun Miyakoshi, Jumpei Kashima, Masayuki Shirasawa, Masahiro Torasawa, Yuji Matsumoto, Ken Masuda, Yuki Shinno, Yusuke Okuma, Tatsuya Yoshida, Yasushi Goto, Hidehito Horinouchi, Kouya Shiraishi, Takashi Kohno, Noboru Yamamoto, Yasushi Yatabe, Yuichiro Ohe

Cancer Res (2024) 84 (6_Supplement): 5146.

https://doi.org/10.1158/1538-7445.AM2024-5146

Published: 22 March 2024

View articletitled, Abstract 5146: Clinical significance of inter-assay discrepancy in PD-L1 expression evaluation for the efficacy of pembrolizumab in advanced NSCLC patients with high PD-L1 expression

Journal Articles

Abstract 6149: Polygenic risk score and lung adenocarcinoma risk among never-smokers by EGFR mutation status

Cancer Res (2024) 84 (6_Supplement): 6149.

https://doi.org/10.1158/1538-7445.AM2024-6149

Published: 22 March 2024

View articletitled, Abstract 6149: Polygenic risk score and lung adenocarcinoma risk among never-smokers by EGFR mutation status

Journal Articles

Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis

Junya Tabata, Takashi Nakaoku, Mitsugu Araki, Ryunosuke Yoshino, Shinji Kohsaka, Ayaka Otsuka, Masachika Ikegami, Ayako Ui, Shin-ichiro Kanno, Keiko Miyoshi, Shigeyuki Matsumoto, Yukari Sagae, Akira Yasui, Masakazu Sekijima, Hiroyuki Mano, Yasushi Okuno, Aikou Okamoto, Takashi Kohno

Cancer Res (2022) 82 (20): 3751–3762.

https://doi.org/10.1158/0008-5472.CAN-22-0834

Published: 17 October 2022

View articletitled, Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis

Includes: Multimedia, Supplementary data

Journal Articles

Single-Cell Transcriptome Profiling Reveals Intratumoral Heterogeneity and Molecular Features of Ductal Carcinoma In Situ

Momoko Tokura, Jun Nakayama, Marta Prieto-Vila, Sho Shiino, Masayuki Yoshida, Tomofumi Yamamoto, Naoaki Watanabe, Shin Takayama, Yutaka Suzuki, Koji Okamoto, Takahiro Ochiya, Takashi Kohno, Yasushi Yatabe, Akihiko Suto, Yusuke Yamamoto

Cancer Res (2022) 82 (18): 3236–3248.

https://doi.org/10.1158/0008-5472.CAN-22-0090

Published: 16 September 2022

View articletitled, Single-Cell Transcriptome Profiling Reveals Intratumoral Heterogeneity and Molecular Features of Ductal Carcinoma In Situ

Includes: Supplementary data

Journal Articles

Abstract 5715: Epigenomic profiling identifies distinct neuroendocrine subtypes in lung cancer with neuroendocrine differentiation

Takashi Sato, Junko Hamamoto, Katsura Emoto, Takahiro Fukushima, Kai Sugihara, Masayuki Shirasawa, Yoshiro Nakahara, Satoshi Igawa, Yoshiki Murakumo, Takashi Kohno, Kouya Shiraishi, Hiroyuki Yasuda, Kenzo Soejima, Hideo Watanabe, Katsuhiko Naoki

Cancer Res (2022) 82 (12_Supplement): 5715.

https://doi.org/10.1158/1538-7445.AM2022-5715

Published: 15 June 2022

View articletitled, Abstract 5715: Epigenomic profiling identifies distinct neuroendocrine subtypes in lung cancer with neuroendocrine differentiation

Journal Articles

Upregulation of FGF9 in Lung Adenocarcinoma Transdifferentiation to Small Cell Lung Cancer

Cancer Res (2021) 81 (14): 3916–3929.

https://doi.org/10.1158/0008-5472.CAN-20-4048

Published: 15 July 2021

View articletitled, Upregulation of FGF9 in Lung Adenocarcinoma Transdifferentiation to Small Cell Lung Cancer

Includes: Supplementary data

Journal Articles

Abstract 2094: Correaltions between genome-wide DNA methylation profiles and genomic driver aberrations during multistage lung adenocaricinogenesis

Kenichi Hamada, Ying Tian, Mao Fujimoto, Takahashi Yoriko, Takashi Kohno, Koji Tsuta, Shun-ichi Watanabe, Teruhiko Yoshida, Hisao Asamura, Yae Kanai, Eri Arai

Cancer Res (2021) 81 (13_Supplement): 2094.

https://doi.org/10.1158/1538-7445.AM2021-2094

Published: 01 July 2021

View articletitled, Abstract 2094: Correaltions between genome-wide DNA methylation profiles and genomic driver aberrations during multistage lung adenocaricinogenesis

Journal Articles

Abstract 1311: Inter- and intra-tumor heterogeneity of genetic and immune profiles in hereditary clear cell renal cell carcinoma

Mariko Tabata, Yusuke Sato, Yasunori Kogure, Marni B. McClure, Yuji Kumade, Yuki Saito, Sumito Shingaki, Kota Yoshifuji, Junji Koya, Kazushi Yoshida, Takashi Kohno, Kenichi Chiba, Ai Okada, Yuichi Shiraishi, Haruki Kume, Keisuke Kataoka

Cancer Res (2020) 80 (16_Supplement): 1311.

https://doi.org/10.1158/1538-7445.AM2020-1311

Published: 15 August 2020

View articletitled, Abstract 1311: Inter- and intra-tumor heterogeneity of genetic and immune profiles in hereditary clear cell renal cell carcinoma

Journal Articles

Abstract 3551: Simple vs. comprehensive prediction models of homologous recombination deficiency based on mutational and clinical features in three independent breast cancer datasets

Maki Tanioka, Tomoko Watanabe, Takayuki Honda, Hirohiko Totsuka, Eri Arai, Yae Kanai, Kouya Shiraishi, Kenji Tamura, Takashi Kohno

Cancer Res (2020) 80 (16_Supplement): 3551.

https://doi.org/10.1158/1538-7445.AM2020-3551

Published: 15 August 2020

View articletitled, Abstract 3551: Simple vs. comprehensive prediction models of homologous recombination deficiency based on mutational and clinical features in three independent breast cancer datasets

Journal Articles

Abstract 918: A secondary RET mutation allosterically conferring resistance to vandetanib

Takashi Nakaoku, Takashi Kohno, Mitsugu Araki, Seiji Nino, Rakhee Chauhan, Phillip P. Knowles, Katsuya Tsuchihara, Shingo Matsumoto, Yoko Shimada, Sachiyo Mimaki, Genichiro Ishii, Hitoshi Ichikawa, Yasushi Okuno, Kiyotaka Yoh, Neil Q. McDonald, Koichi Goto

Cancer Res (2018) 78 (13_Supplement): 918.

https://doi.org/10.1158/1538-7445.AM2018-918

Published: 01 July 2018

View articletitled, Abstract 918: A secondary RET mutation allosterically conferring resistance to vandetanib

Journal Articles

Abstract 5378: Genes involved in development and differentiation are commonly methylated in cancers derived from multiple organs: A single-institutional methylome analysis using 1007 tissue specimens

Kentaro Ohara, Eri Arai, Yoriko Takahashi, Nanako Ito, Ayako Shibuya, Koji Tsuta, Ryoji Kushima, Hitoshi Tsuda, Hidenori Ojima, Hiroyuki Fujimoto, Shun-ichi Watanabe, Hitoshi Katai, Takayuki Kinoshita, Tatsuhiro Shibata, Takashi Kohno, Yae Kanai

Cancer Res (2017) 77 (13_Supplement): 5378.

https://doi.org/10.1158/1538-7445.AM2017-5378

Published: 01 July 2017

View articletitled, Abstract 5378: Genes involved in development and differentiation are commonly methylated in cancers derived from multiple organs: A single-institutional methylome analysis using 1007 tissue specimens

Journal Articles

Abstract 2248: Common TDP1 polymorphisms in relation to survival among small cell lung cancer patients in a multicenter study from the International Lung Cancer Consortium

Cancer Res (2017) 77 (13_Supplement): 2248.

https://doi.org/10.1158/1538-7445.AM2017-2248

Published: 01 July 2017

View articletitled, Abstract 2248: Common TDP1 polymorphisms in relation to survival among small cell lung cancer patients in a multicenter study from the International Lung Cancer Consortium

Journal Articles

Abstract 2468: Gene aberrations for precision medicine against lung adenocarcinoma

Motonobu Saito, Koji Kono, Takashi Kohno

Cancer Res (2017) 77 (13_Supplement): 2468.

https://doi.org/10.1158/1538-7445.AM2017-2468

Published: 01 July 2017

View articletitled, Abstract 2468: Gene aberrations for precision medicine against lung adenocarcinoma

Journal Articles

Abstract 1432: Precision lung cancer medicine based on information on cancer and the host genomes

Takashi Kohno, Kouya Shiraishi, Kazushi Yoshida, Motonobu Saito, Yukinori Okada

Cancer Res (2017) 77 (13_Supplement): 1432.

https://doi.org/10.1158/1538-7445.AM2017-1432

Published: 01 July 2017

View articletitled, Abstract 1432: Precision lung cancer medicine based on information on cancer and the host genomes

Journal Articles

Abstract 2568: Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women

Cancer Res (2016) 76 (14_Supplement): 2568.

https://doi.org/10.1158/1538-7445.AM2016-2568

Published: 15 July 2016

View articletitled, Abstract 2568: Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women

Journal Articles

Oncogenic Fusion Gene CD74-NRG1 Confers Cancer Stem Cell–like Properties in Lung Cancer through a IGF2 Autocrine/Paracrine Circuit

Takahiko Murayama, Takashi Nakaoku, Masato Enari, Tatsunori Nishimura, Kana Tominaga, Asuka Nakata, Arinobu Tojo, Sumio Sugano, Takashi Kohno, Noriko Gotoh

Cancer Res (2016) 76 (4): 974–983.

https://doi.org/10.1158/0008-5472.CAN-15-2135

Published: 14 February 2016

View articletitled, Oncogenic Fusion Gene CD74-NRG1 Confers Cancer Stem Cell–like Properties in Lung Cancer through a IGF2 Autocrine/Paracrine Circuit

Journal Articles

Abstract A1-55: Combination of a three-microRNA signature and TP53 genotype predicts responses to platinum-based doublet chemotherapy in patients with lung adenocarcinoma

Kouya Shiraishi, Motonobu Saito, Takashi Kohno

Cancer Res (2015) 75 (22_Supplement_1): A1-55.

https://doi.org/10.1158/1538-7445.TRANSCAGEN-A1-55

Published: 15 November 2015

View articletitled, Abstract A1-55: Combination of a three-microRNA signature and TP53 genotype predicts responses to platinum-based doublet chemotherapy in patients with lung adenocarcinoma

Journal Articles

KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

Cancer Res (2015) 75 (18): 3936–3945.

https://doi.org/10.1158/0008-5472.CAN-14-3702

Published: 14 September 2015

View articletitled, KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

Includes: Supplementary data

Journal Articles

Abstract 4669: Druggable oncogene fusions in lung invasive mucinous adenocarcinoma

Takashi Nakaoku, Koji Tsuta, Hitoshi Ichikawa, Kouya Shiraishi, Hiromi Sakamoto, Masato Enari, Koh Furuta, Yoko Shimada, Hideaki Ogiwara, Shun-ichi Watanabe, Hiroshi Nokihara, Kazuki Yasuda, Masaki Hiramoto, Takao Nammo, Young Hak Kim, Michiaki Mishima, Jun Yokota, Teruhiko Yoshida, Takashi Kohno

Cancer Res (2015) 75 (15_Supplement): 4669.

https://doi.org/10.1158/1538-7445.AM2015-4669

Published: 01 August 2015

View articletitled, Abstract 4669: Druggable oncogene fusions in lung invasive mucinous adenocarcinoma

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Abstract 5355: Whole genome landscape of small cell lung carcinoma and large cell neuroendocrine carcinoma of the lung

Abstract 5146: Clinical significance of inter-assay discrepancy in PD-L1 expression evaluation for the efficacy of pembrolizumab in advanced NSCLC patients with high PD-L1 expression

Abstract 6149: Polygenic risk score and lung adenocarcinoma risk among never-smokers by EGFR mutation status

Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis

Single-Cell Transcriptome Profiling Reveals Intratumoral Heterogeneity and Molecular Features of Ductal Carcinoma In Situ

Abstract 5715: Epigenomic profiling identifies distinct neuroendocrine subtypes in lung cancer with neuroendocrine differentiation

Upregulation of FGF9 in Lung Adenocarcinoma Transdifferentiation to Small Cell Lung Cancer

Abstract 2094: Correaltions between genome-wide DNA methylation profiles and genomic driver aberrations during multistage lung adenocaricinogenesis

Abstract 1311: Inter- and intra-tumor heterogeneity of genetic and immune profiles in hereditary clear cell renal cell carcinoma

Abstract 3551: Simple vs. comprehensive prediction models of homologous recombination deficiency based on mutational and clinical features in three independent breast cancer datasets

Abstract 918: A secondary RET mutation allosterically conferring resistance to vandetanib

Abstract 5378: Genes involved in development and differentiation are commonly methylated in cancers derived from multiple organs: A single-institutional methylome analysis using 1007 tissue specimens

Abstract 2248: Common TDP1 polymorphisms in relation to survival among small cell lung cancer patients in a multicenter study from the International Lung Cancer Consortium

Abstract 2468: Gene aberrations for precision medicine against lung adenocarcinoma

Abstract 1432: Precision lung cancer medicine based on information on cancer and the host genomes

Abstract 2568: Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women

Oncogenic Fusion Gene CD74-NRG1 Confers Cancer Stem Cell–like Properties in Lung Cancer through a IGF2 Autocrine/Paracrine Circuit

Abstract A1-55: Combination of a three-microRNA signature and TP53 genotype predicts responses to platinum-based doublet chemotherapy in patients with lung adenocarcinoma

KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

Abstract 4669: Druggable oncogene fusions in lung invasive mucinous adenocarcinoma

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