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Takahiro Taguchi
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Journal Articles

Unbiased Compound Screening Identifies Unexpected Drug Sensitivities and Novel Treatment Options for Gastrointestinal Stromal Tumors

Sergei Boichuk, Derek J. Lee, Keith R. Mehalek, Kathleen R. Makielski, Agnieszka Wozniak, Danushka S. Seneviratne, Nina Korzeniewski, Rolando Cuevas, Joshua A. Parry, Matthew F. Brown, James Zewe, Takahiro Taguchi, Shin-Fan Kuan, Patrick Schöffski, Maria Debiec-Rychter, Anette Duensing
Journal: Cancer Research
Series: Author Choice
Cancer Res (2014) 74 (4): 1200–1213.
https://doi.org/10.1158/0008-5472.CAN-13-1955
Published: 16 February 2014
View articletitled, Unbiased Compound Screening Identifies Unexpected Drug Sensitivities and Novel Treatment Options for Gastrointestinal Stromal Tumors
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Includes: Supplementary data
Journal Articles

DOG1 Regulates Growth and IGFBP5 in Gastrointestinal Stromal Tumors

Susanne Simon, Florian Grabellus, Loretta Ferrera, Luis Galietta, Benjamin Schwindenhammer, Thomas Mühlenberg, Georg Taeger, Grant Eilers, Juergen Treckmann, Frank Breitenbuecher, Martin Schuler, Takahiro Taguchi, Jonathan A. Fletcher, Sebastian Bauer
Journal: Cancer Research
Cancer Res (2013) 73 (12): 3661–3670.
https://doi.org/10.1158/0008-5472.CAN-12-3839
Published: 13 June 2013
View articletitled, DOG1 Regulates Growth and IGFBP5 in Gastrointestinal Stromal Tumors
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Includes: Supplementary data
Journal Articles

Abstract 1035: Crenolanib, a highly selective platelet-derived growth factor receptor α/β (PDGFRA/B) tyrosine kinase inhibitor, destabilizes ETV1 protein in KIT-mutant gastrointestinal stromal tumor (GIST) cells.

Yujiro Hayashi, Michael R. Bardsley, Yoshitaka Toyomasu, Takahiro Taguchi, Brian P. Rubin, Monique Carter, Abhijit Ramachandran, Tamas Ordog
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1035.
https://doi.org/10.1158/1538-7445.AM2013-1035
Published: 15 April 2013
View articletitled, Abstract 1035: Crenolanib, a highly selective platelet-derived growth factor receptor α/β (PDGFRA/B) tyrosine kinase inhibitor, destabilizes ETV1 protein in KIT-mutant gastrointestinal stromal tumor (GIST) cells.
Journal Articles

Abstract 3392: New findings of kinase switch in gastrointestinal stromal tumor under imatinib using phosphoproteomic analysis.

Maiko Ako, Tsuyoshi Takahashi, Satoshi Serada, Minoru Fujimoto, Yasuaki Miyazaki, Kazuki Shimada, Takayuki Ikezoe, Takahiro Taguchi, Yukinori Kurokawa, Makoto Yamasaki, Hiroshi Miyata, Kiyokazu Nakajima, Shuji Takiguchi, Masaki Mori, Yuichirou Doki, Tetsuji Naka, Toshirou Nishida
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3392.
https://doi.org/10.1158/1538-7445.AM2013-3392
Published: 15 April 2013
View articletitled, Abstract 3392: New findings of kinase switch in gastrointestinal stromal tumor under imatinib using phosphoproteomic analysis.
Journal Articles

Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors

Takeshi Niinuma, Hiromu Suzuki, Masanori Nojima, Katsuhiko Nosho, Hiroyuki Yamamoto, Hiroyuki Takamaru, Eiichiro Yamamoto, Reo Maruyama, Takayuki Nobuoka, Yasuaki Miyazaki, Toshirou Nishida, Takeo Bamba, Tatsuo Kanda, Yoichi Ajioka, Takahiro Taguchi, Satoshi Okahara, Hiroaki Takahashi, Yasunori Nishida, Masao Hosokawa, Tadashi Hasegawa, Takashi Tokino, Koichi Hirata, Kohzoh Imai, Minoru Toyota, Yasuhisa Shinomura
Journal: Cancer Research
Cancer Res (2012) 72 (5): 1126–1136.
https://doi.org/10.1158/0008-5472.CAN-11-1803
Published: 01 March 2012
View articletitled, Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors
Open the PDF for Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors in another window
Includes: Supplementary data
Journal Articles

Abstract 3824: Molecular cytogenetic study of a new human rhabdomyosarcoma cell line, HS-RMS-2, with various highly- amplified DNA sequences

Takahiro Taguchi, Hiroshi Sonobe, Eiji Takaoka, Kunihiro Akimaru, Shuji Sakamoto, Taro Shuin, Masanori Daibata, Akira Tominaga
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3824.
https://doi.org/10.1158/1538-7445.AM2011-3824
Published: 15 April 2011
View articletitled, Abstract 3824: Molecular cytogenetic study of a new human rhabdomyosarcoma cell line, HS-RMS-2, with various highly- amplified DNA sequences
Journal Articles

Abstract 4520: Arginine deprivation therapy in malignant peripheral nerve sheath tumor and gastrointestinal stromal tumor: potential therapeutic effects of pegylated arginine deiminase in argininosuccinate synthetase negative sarcomas

Munir Tanas, Jessica Hespelt, Takahiro Taguchi, John Bomalski, Brian Rubin
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4520.
https://doi.org/10.1158/1538-7445.AM10-4520
Published: 15 April 2010
View articletitled, Abstract 4520: Arginine deprivation therapy in malignant peripheral nerve sheath tumor and gastrointestinal stromal tumor: potential therapeutic effects of pegylated arginine deiminase in argininosuccinate synthetase negative sarcomas
Journal Articles

Abstract 1171: Gastrointestinal stromal tumors (GIST) cell proliferation inhibition with combined adenoviral and molecular targeted therapy

Derron E. Allen, J. Pablo Arnoletti, Martin J. Heslin, Takahiro Taguchi, Elena A. Kashentseva, Igor Dmitriev, Andrey Frolov
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1171.
https://doi.org/10.1158/1538-7445.AM10-1171
Published: 15 April 2010
View articletitled, Abstract 1171: Gastrointestinal stromal tumors (GIST) cell proliferation inhibition with combined adenoviral and molecular targeted therapy
Journal Articles

Detection of Treatment-Induced Changes in Signaling Pathways in Gastrointestinal Stromal Tumors Using Transcriptomic Data

Michael F. Ochs, Lori Rink, Chi Tarn, Sarah Mburu, Takahiro Taguchi, Burton Eisenberg, Andrew K. Godwin
Journal: Cancer Research
Cancer Res (2009) 69 (23): 9125–9132.
https://doi.org/10.1158/0008-5472.CAN-09-1709
Published: 30 November 2009
View articletitled, Detection of Treatment-Induced Changes in Signaling Pathways in Gastrointestinal Stromal Tumors Using Transcriptomic Data
Open the PDF for Detection of Treatment-Induced Changes in Signaling Pathways in Gastrointestinal Stromal Tumors Using Transcriptomic Data in another window
Includes: Supplementary data
Journal Articles

Inhibitors of Deacetylases Suppress Oncogenic KIT Signaling, Acetylate HSP90, and Induce Apoptosis in Gastrointestinal Stromal Tumors

Thomas Mühlenberg, Yixiang Zhang, Andrew J. Wagner, Florian Grabellus, James Bradner, Georg Taeger, Hauke Lang, Takahiro Taguchi, Martin Schuler, Jonathan A. Fletcher, Sebastian Bauer
Journal: Cancer Research
Cancer Res (2009) 69 (17): 6941–6950.
https://doi.org/10.1158/0008-5472.CAN-08-4004
Published: 31 August 2009
View articletitled, Inhibitors of Deacetylases Suppress Oncogenic KIT Signaling, Acetylate HSP90, and Induce Apoptosis in Gastrointestinal Stromal Tumors
Open the PDF for Inhibitors of Deacetylases Suppress Oncogenic KIT Signaling, Acetylate HSP90, and Induce Apoptosis in Gastrointestinal Stromal Tumors in another window
Includes: Supplementary data
Journal Articles

Therapeutic Effect of Imatinib in Gastrointestinal Stromal Tumors: AKT Signaling Dependent and Independent Mechanisms

Chi Tarn, Yuliya V. Skorobogatko, Takahiro Taguchi, Burton Eisenberg, Margaret von Mehren, Andrew K. Godwin
Journal: Cancer Research
Cancer Res (2006) 66 (10): 5477–5486.
https://doi.org/10.1158/0008-5472.CAN-05-3906
Published: 16 May 2006
View articletitled, Therapeutic Effect of Imatinib in Gastrointestinal Stromal Tumors: AKT Signaling Dependent and Independent Mechanisms
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Journal Articles

Effects of imatinib vary with the types of kit-mutation in gist cell lines

Kazuhiro Noma, Minoru Haisa, Yoshio Naomoto, Yasuhiro Shirakawa, Nobuyuki Kamo, Toshihiro Murata, Takayuki Motoki, Tomoki Yamatsuji, Junnji Matsuoka, Yasuko Tomono, Hiroyuki Ohmori, Takahiro Taguchi, Noriaki Tanaka
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1014.
Published: 01 April 2004
View articletitled, Effects of imatinib vary with the types of kit-mutation in gist cell lines
Journal Articles

Identification of a Gene Containing Zinc-Finger Motifs Based on Lost Expression in Malignantly Transformed Rat Ovarian Surface Epithelial Cells

Abbas Abdollahi, Andrew K. Godwin, Paul D. Miller, Lori A. Getts, David C. Schultz, Takahiro Taguchi, Joseph R. Testa, Thomas C. Hamilton
Journal: Cancer Research
Cancer Res (1997) 57 (10): 2029–2034.
Published: 01 May 1997
View articletitled, Identification of a Gene Containing Zinc-Finger Motifs Based on Lost Expression in Malignantly Transformed Rat Ovarian Surface Epithelial Cells
Open the PDF for Identification of a Gene Containing Zinc-Finger Motifs Based on Lost Expression in Malignantly Transformed Rat Ovarian Surface Epithelial Cells in another window
Journal Articles

Recurrent Deletions of Specific Chromosomal Sites in 1p, 3p, 6q, and 9p in Human Malignant Mesothelioma

Takahiro Taguchi, Suresh C. Jhanwar, Jill M. Siegfried, Steven M. Keller, Joseph R. Testa
Journal: Cancer Research
Cancer Res (1993) 53 (18): 4349–4355.
Published: 01 September 1993
View articletitled, Recurrent Deletions of Specific Chromosomal Sites in 1p, 3p, 6q, and 9p in Human Malignant Mesothelioma
Open the PDF for Recurrent Deletions of Specific Chromosomal Sites in 1p, 3p, 6q, and 9p in Human Malignant Mesothelioma in another window