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Journal Articles

Direct Targeting of MYCN Gene Amplification by Site-Specific DNA Alkylation in Neuroblastoma

Hiroyuki Yoda, Takahiro Inoue, Yoshinao Shinozaki, Jason Lin, Takayoshi Watanabe, Nobuko Koshikawa, Atsushi Takatori, Hiroki Nagase

Cancer Res (2019) 79 (4): 830–840.

DOI: https://doi.org/10.1158/0008-5472.CAN-18-1198

Published: 15 February 2019

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Includes: Supplementary data

Journal Articles

Abstract 2711: Development of a new innovative multifunctional immune checkpoint inhibitor

Hiroki Nagase, Keiko Fukushima, Asuka Hattori, Mayu Shinohara, Atsushi Takatori, Takayoshi Watanabe, Nobuko Koshikawa, Takahiro Inoue, Jason Lin, Yoshinao Shinozaki

Cancer Res (2018) 78 (13_Supplement): 2711.

DOI: https://doi.org/10.1158/1538-7445.AM2018-2711

Published: 01 July 2018

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Journal Articles

Abstract 2041: High-throughput chemical screening for sensitization of bladder cancer to gemcitabine and cisplatin chemotherapy

Yuki Kita, Takashi Kobayashi, Ryouichi Saito, Toshinari Yamasaki, Takahiro Inoue, Osamu Ogawa

Cancer Res (2017) 77 (13_Supplement): 2041.

DOI: https://doi.org/10.1158/1538-7445.AM2017-2041

Published: 01 July 2017

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Journal Articles

Abstract 3775: Mutated cancer cell-specific cell death activity of alkylating Pyrrole-Imidazole polyamide conjugates targeting a variety of oncogenic driver gene mutations

Hiroki Nagase, Kiriko Hiraoka, Takahiro Inoue, Hiroyuki Yoda, Krishnamurthy Sakthisri, Jason Lin, Takayoshi Watanabe, Nobuko Koshikawa, Atsushi Takatori

Cancer Res (2016) 76 (14_Supplement): 3775.

DOI: https://doi.org/10.1158/1538-7445.AM2016-3775

Published: 15 July 2016

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Journal Articles

Abstract 5046: High-throughput chemical screening for sensitization of bladder cancer to gemcitabine and cisplatin chemotherapy

Yuki Kita, Takashi Kobayashi, Norihiko Masuda, Atsuro Sawada, Yoshiyuki Matsui, Takahiro Inoue, Tomomi Kamba, Osamu Ogawa

Cancer Res (2016) 76 (14_Supplement): 5046.

DOI: https://doi.org/10.1158/1538-7445.AM2016-5046

Published: 15 July 2016

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Journal Articles

Abstract 4691: KRAS mutation specific alkylating pyrrole-imidazole polyamide (KR12) suppresses mutant KRAS expression and inhibits tumor growth by showing accumulation in KRAS mutant xenografts

Takahiro Inoue, Kiriko Hiraoka, Yusei Suzuki, Hiroyuki Yoda, Takayoshi Watanabe, Atsushi Takatori, Nobuko Koshikawa, Toshinori Ozaki, Hiroki Nagase

Cancer Res (2015) 75 (15_Supplement): 4691.

DOI: https://doi.org/10.1158/1538-7445.AM2015-4691

Published: 01 August 2015

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Journal Articles

Abstract 4687: A novel alkylating pyrrol-imidazole polyamide, KR12, specifically recognizes mutant KRAS genes and potently induces cell death

Kiriko Hiraoka, Takahiro Inoue, Hiroyuki Yoda, Atsushi Takatori, Takayoshi Watanabe, Nobuko Koshikawa, Toshinori Ozaki, Hiroki Nagase

Cancer Res (2015) 75 (15_Supplement): 4687.

DOI: https://doi.org/10.1158/1538-7445.AM2015-4687

Published: 01 August 2015

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Journal Articles

Abstract 2602: KRAS G12D and G12V specific alkylating agent (KR12) inhibits growth of colon cancer with those KRAS mutations in vitro as well as in vivo

Hiroki Nagase, Kiriko Hiraoka, Takahiro Inoue, Takayoshi Watanabe, Ken-Ichi Shinohara, Nobuko Koshikawa, Ozaki Toshinori

Cancer Res (2014) 74 (19_Supplement): 2602.

DOI: https://doi.org/10.1158/1538-7445.AM2014-2602

Published: 01 October 2014

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Journal Articles

Abstract 4677: Non-prostate cancer death within 5 years after radical therapy in men with localized prostate cancer.

Takashi Kobayashi, Tomomi Kamba, Naoki Terada, Toshinari Yamasaki, Itaru Ikeda, Haruo Inokuchi, Yoshiki Norihisa, Takashi Mizowaki, Takahiro Inoue, Kazutoshi Okubo, Koji Yoshimura, Masahiro Hiraoka, Osamu Ogawa

Cancer Res (2013) 73 (8_Supplement): 4677.

DOI: https://doi.org/10.1158/1538-7445.AM2013-4677

Published: 15 April 2013

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Journal Articles

Abstract 1920: Variation of ERG oncoprotein expression in prostate cancer patients with different ethnicities.

Gyorgy Petrovics, Sudhir Rawal, Molly Williams, Philip Rosen, David Pfister, Takahiro Inoue, Osamu Ogawa, Monica Colombo, Yongmei Chen, Denise Young, Albert Dobi, David G. McLeod, Isabell Sesterhenn, Shiv Srivastava

Cancer Res (2013) 73 (8_Supplement): 1920.

DOI: https://doi.org/10.1158/1538-7445.AM2013-1920

Published: 15 April 2013

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Journal Articles

Abstract 300: Regulation of androgen receptor transactivity and mTOR-S6 kinase pathway by Rheb in prostate cancer cell proliferation

Takashi Kobayashi, Takahiro Inoue, Yosuke Shimizu, Naoki Terada, Toshinari Yamasaki, Eijiro Nakamura, Yoshinobu Toda, Hiroyuki Nishiyama, Toshiyuki Kamoto, Osamu Ogawa

Cancer Res (2010) 70 (8_Supplement): 300.

DOI: https://doi.org/10.1158/1538-7445.AM10-300

Published: 15 April 2010

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Journal Articles

Identification of EP4 as a Potential Target for the Treatment of Castration-Resistant Prostate Cancer Using a Novel Xenograft Model

Naoki Terada, Yosuke Shimizu, Tomomi Kamba, Takahiro Inoue, Atsushi Maeno, Takashi Kobayashi, Eijiro Nakamura, Toshiyuki Kamoto, Toshiya Kanaji, Takayuki Maruyama, Yoshiki Mikami, Yoshinobu Toda, Toshiyuki Matsuoka, Yasushi Okuno, Gozoh Tsujimoto, Shuh Narumiya, Osamu Ogawa

Cancer Res (2010) 70 (4): 1606–1615.

DOI: https://doi.org/10.1158/0008-5472.CAN-09-2984

Published: 14 February 2010

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Journal Articles

Androgen-dependent regulation of protein kinase Cζ and its roles for progression to androgen independency in prostate cancer cells

Takashi Kobayashi, Takahiro Inoue, Naoki Terada, Yosuke Shimizu, Toshinari Yamasaki, Toshiyuki Kamoto, Osamu Ogawa, Eijiro Nakamura

Cancer Res (2008) 68 (9_Supplement): 3487.

Published: 01 May 2008

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Journal Articles

Androgen-dependent regulation of protein kinase Cζ and its roles for progression to androgen independency in prostate cancer cells

Takashi Kobayashi, Takahiro Inoue, Naoki Terada, Yosuke Shimizu, Toshinari Yamasaki, Toshiyuki Kamoto, Osamu Ogawa, Eijiro Nakamura

Cancer Res (2007) 67 (9_Supplement): 998.

Published: 01 May 2007

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Journal Articles

Antiandrogen Bicalutamide Promotes Tumor Growth in a Novel Androgen-Dependent Prostate Cancer Xenograft Model Derived from a Bicalutamide-Treated Patient

Toru Yoshida, Hidefumi Kinoshita, Takehiko Segawa, Eijiro Nakamura, Takahiro Inoue, Yousuke Shimizu, Toshiyuki Kamoto, Osamu Ogawa

Cancer Res (2005) 65 (21): 9611–9616.

DOI: https://doi.org/10.1158/0008-5472.CAN-05-0817

Published: 01 November 2005

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NARROW

Direct Targeting of MYCN Gene Amplification by Site-Specific DNA Alkylation in Neuroblastoma

Abstract 2711: Development of a new innovative multifunctional immune checkpoint inhibitor

Abstract 2041: High-throughput chemical screening for sensitization of bladder cancer to gemcitabine and cisplatin chemotherapy

Abstract 3775: Mutated cancer cell-specific cell death activity of alkylating Pyrrole-Imidazole polyamide conjugates targeting a variety of oncogenic driver gene mutations

Abstract 5046: High-throughput chemical screening for sensitization of bladder cancer to gemcitabine and cisplatin chemotherapy

Abstract 4691: KRAS mutation specific alkylating pyrrole-imidazole polyamide (KR12) suppresses mutant KRAS expression and inhibits tumor growth by showing accumulation in KRAS mutant xenografts

Abstract 4687: A novel alkylating pyrrol-imidazole polyamide, KR12, specifically recognizes mutant KRAS genes and potently induces cell death

Abstract 2602: KRAS G12D and G12V specific alkylating agent (KR12) inhibits growth of colon cancer with those KRAS mutations in vitro as well as in vivo

Abstract 4677: Non-prostate cancer death within 5 years after radical therapy in men with localized prostate cancer.

Abstract 1920: Variation of ERG oncoprotein expression in prostate cancer patients with different ethnicities.

Abstract 300: Regulation of androgen receptor transactivity and mTOR-S6 kinase pathway by Rheb in prostate cancer cell proliferation

Identification of EP4 as a Potential Target for the Treatment of Castration-Resistant Prostate Cancer Using a Novel Xenograft Model

Androgen-dependent regulation of protein kinase Cζ and its roles for progression to androgen independency in prostate cancer cells

Androgen-dependent regulation of protein kinase Cζ and its roles for progression to androgen independency in prostate cancer cells

Antiandrogen Bicalutamide Promotes Tumor Growth in a Novel Androgen-Dependent Prostate Cancer Xenograft Model Derived from a Bicalutamide-Treated Patient

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