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Suzanne Russo
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Journal Articles

Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics

Sonam Bhatia, Melissa Kramer, Suzanne Russo, Payal Naik, Gayatri Arun, Kyle Brophy, Peter Andrews, Cheng Fan, Charles M. Perou, Jonathan Preall, Taehoon Ha, Dennis Plenker, David A. Tuveson, Arvind Rishi, John E. Wilkinson, W. Richard McCombie, Karen Kostroff, David L. Spector
Journal: Cancer Research
Cancer Res (2022) 82 (7): 1174–1192.
https://doi.org/10.1158/0008-5472.CAN-21-2807
Published: 01 April 2022
View article titled, Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics
Open the PDF for Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics in another window
Includes: Supplementary data
Journal Articles

Abstract 950: Antitumor activity of a novel phosphodiesterase 10 inhibitor in an orthotopic mouse model of lung cancer

Veronica Ramirez-Alcantara, Michele Schuler, Bing Zhu, Nan Li, Evrim Gurpinar, Dennis Otali, Joshua Canzoneri, Adam Keeton, Bernard Gary, Suzanne Russo, Lori Coward, Gregory Gorman, William Grizzle, Xi Chen, Michael Boyd, Gary Piazza
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 950.
https://doi.org/10.1158/1538-7445.AM2015-950
Published: 01 August 2015
View article titled, Abstract 950: Antitumor activity of a novel phosphodiesterase 10 inhibitor in an orthotopic mouse model of lung cancer
Journal Articles

Abstract 4360: Validation of phosphodiesterase 10A as a cancer target

Kevin Lee, Nan Li, Xi Chen, Bing Zhu, Larry Yet, Luciana Madeira da Silva, Suzanne Russo, Adam B. Keeton, Michael R. Boyd, Gary A. Piazza
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4360.
https://doi.org/10.1158/1538-7445.AM2015-4360
Published: 01 August 2015
View article titled, Abstract 4360: Validation of phosphodiesterase 10A as a cancer target
Journal Articles

Abstract 1773: Phosphodiesterase 10A: A novel target for selective inhibition of colon tumor cell growth and Wnt/β-catenin signaling

Nan Li, Kevin Lee, Yaguang Xi, Bing Zhu, Bernary D. Gary, Verónica Ramírez-Alcántara, Evrim Gurpinar, Joshua C. Canzoneri, Alexandra Fajardo, Sara Sigler, John T. Piazza, Xi Chen, Joel Andrews, Wenyan Lu, Yonghe Li, Suzanne Russo, Larry Yet, Adam B. Keeton, William E. Grizzle, Gary A. Piazza
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1773.
https://doi.org/10.1158/1538-7445.AM2014-1773
Published: 01 October 2014
View article titled, Abstract 1773: Phosphodiesterase 10A: A novel target for selective inhibition of colon tumor cell growth and Wnt/β-catenin signaling
Journal Articles

Abstract 1768: A novel PDE10 inhibitor suppresses tumor growth in an orthotopic mouse model of lung cancer

Veronica Ramirez-Alcantara, Michele A. Schuler, Bing Zhu, Nan Li, Evrim Gurpinar, Joshua Canzoneri, Adam Keeton, Bernard Gary, Suzanne Russo, Lori Coward, Gregory S. Gorman, William Grizzle, Xi Chen, Gary A. Piazza
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1768.
https://doi.org/10.1158/1538-7445.AM2014-1768
Published: 01 October 2014
View article titled, Abstract 1768: A novel PDE10 inhibitor suppresses tumor growth in an orthotopic mouse model of lung cancer
Journal Articles

Abstract 1632: Co-targeting mTOR and IGF-1R/IR results in synergistic activity against a broad array of tumor cell lines, independent of KRAS mutation status

Sharon Barr, Suzanne Russo, Elizabeth Buck, David Epstein, Mark Miglarese
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1632.
https://doi.org/10.1158/1538-7445.AM10-1632
Published: 15 April 2010
View article titled, Abstract 1632: Co-targeting mTOR and IGF-1R/IR results in synergistic activity against a broad array of tumor cell lines, independent of <em>KRAS</em> mutation status
Journal Articles

Abstract #1839: OXA-01, a selective inhibitor of mTORC1/mTORC2, enhances apoptosis induced by chemotherapeutic agents through inhibition of Akt phosphorylation

Sharon Barr, Suzanne Russo, Paul Maresca, Andrew Garton, Andrew Crew, Shripad Bhagwat, Kenneth Iwata, David Epstein, Jonathan Pachter, Mark Miglarese
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1839.
Published: 01 May 2009
View article titled, Abstract #1839: OXA-01, a selective inhibitor of mTORC1/mTORC2, enhances apoptosis induced by chemotherapeutic agents through inhibition of Akt phosphorylation
Journal Articles

Erlotinib inhibits signaling mediated by the ligand-independent EGFR variant III mutant

Sharon Barr, Suzanne Russo, Elizabeth Buck, Stuart Thomson, John Haley, Mark Miglarese, Kenneth Iwata
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2560.
Published: 01 May 2008
View article titled, Erlotinib inhibits signaling mediated by the ligand-independent EGFR variant III mutant
Journal Articles

Characterization of the molecular determinants of Erlotinib sensitivity in NSCLC cell lines

Graeme Griffin, April Thelemann, Siobhan McCormack, Filippo Petti, Eric Brown, Victoria Drewett, Iain Mulford, Stuart Thomson, Feng-Lei Sun, Suzanne Russo, David Keane, Julie Kan, Andrew Garton, David Emerson, John Haley, Lee Arnold, Neil Gibson
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 543.
Published: 01 May 2005
View article titled, Characterization of the molecular determinants of Erlotinib sensitivity in NSCLC cell lines
Journal Articles

Cell screens with siRNA for cancer target identification

Julie L. C. Kan, Feng-Lei Sun, David M. Keane, Suzanne Russo, Nancy Ng, Neil W. Gibson, Lee Arnold
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 402.
Published: 01 May 2005
View article titled, Cell screens with siRNA for cancer target identification
Journal Articles

Identification of potent CYP26 inhibitors and their potential for cancer therapy.

Julie L. C. Kan, Shannon L. Winski, Andrew Cooke, Suzanne Russo, Feng Lei Sun, David Keane, Shripad V. Bhagwat, Mary Srebernak, Mike Vrkljan, Carrie Ecker, Gia Fischetti, Diane Triebe, Vanessa Smith, Cara Cesario, Patricia A. Beck, Anthony I. Nigro, Andy Flood, Paul Briner, Arlindo Castelhano, David Emerson, Neil W. Gibson, Mark J. Mulvihill
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 472.
Published: 01 April 2004
View article titled, Identification of potent CYP26 inhibitors and their potential for cancer therapy.
Journal Articles

Structure activity relationships for a novel series of highly potent and selective naphthyl-derived CYP26 inhibitors.

Mark J. Mulvihill, Arlindo Castelhano, Vanessa Smith, Cara Cesario, Patricia A. Beck, Anthony I. Nigro, Shripad V. Bhagwat, Carrie Ecker, Gia Fischetti, David Keane, Suzanne Russo, Mary Srebernak, Feng-Lei Sun, Diane Triebe, Andrew Cooke, Mike Vrkljan, Shannon L. Winski, Andy Flood, Paul Briner, David Emerson, Neil Gibson, Julie L. C. Kan
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 577.
Published: 01 April 2004
View article titled, Structure activity relationships for a novel series of highly potent and selective naphthyl-derived CYP26 inhibitors.