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Susan L. Mooberry
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Journal Articles

Abstract 6397: Eribulin acts as an immune adjuvant to enhance the antitumor efficacy of STING agonists in triple-negative breast cancer models

Leila Takahashi-Ruiz, Charles S. Fermaintt, Nancy Wilkinson, Peter Y. Chan, Susan L. Mooberry, April L. Risinger
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6397.
https://doi.org/10.1158/1538-7445.AM2023-6397
Published: 04 April 2023
View article titled, Abstract 6397: Eribulin acts as an immune adjuvant to enhance the antitumor efficacy of STING agonists in triple-negative breast cancer models
Journal Articles

Abstract PS16-14: Eribulin and paclitaxel differentially affect exosome formation and release from triple negative breast cancer cells

Petra EJ Pederson, Huiyun Liang, Susan L Mooberry
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS16-14.
https://doi.org/10.1158/1538-7445.SABCS20-PS16-14
Published: 15 February 2021
View article titled, Abstract PS16-14: Eribulin and paclitaxel differentially affect exosome formation and release from triple negative breast cancer cells
Journal Articles

Abstract PS17-18: Eribulin-mediated release of mitochondrial DNA activates the cGAS-STING innate immune signaling pathway

Charles Steven Fermaintt, Leila Takahashi-Ruiz, Susan L Mooberry, April L Risinger
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS17-18.
https://doi.org/10.1158/1538-7445.SABCS20-PS17-18
Published: 15 February 2021
View article titled, Abstract PS17-18: Eribulin-mediated release of mitochondrial DNA activates the cGAS-STING innate immune signaling pathway
Journal Articles

Abstract 1786: High expression of NCX-1 in triple negative breast cancer cell lines identifies a potential biomarker for sensitivity to cardiac glycosides

Petra E. Pederson, Shengxin Cai, Chase M. Carver, Tanja Grkovic, Barry R. O'Keefe, April L. Risinger, Robert H. Cichewicz, Susan L. Mooberry
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1786.
https://doi.org/10.1158/1538-7445.AM2020-1786
Published: 15 August 2020
View article titled, Abstract 1786: High expression of NCX-1 in triple negative breast cancer cell lines identifies a potential biomarker for sensitivity to cardiac glycosides
Journal Articles

Abstract P6-07-02: Evaluating the effects of eribulin and paclitaxel on exosome formation and release from triple negative breast cancer cells

Petra Elizabeth Jans Pederson, Susan L Mooberry
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P6-07-02.
https://doi.org/10.1158/1538-7445.SABCS19-P6-07-02
Published: 15 February 2020
View article titled, Abstract P6-07-02: Evaluating the effects of eribulin and paclitaxel on exosome formation and release from triple negative breast cancer cells
Journal Articles

Abstract P5-05-03: Eribulin treatment activates type 1 IFNs to promote a gene expression signature associated with antitumor immunity

Charles S Fermaintt, Shayne Hastings, Susan L Mooberry, April L Risinger
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P5-05-03.
https://doi.org/10.1158/1538-7445.SABCS19-P5-05-03
Published: 15 February 2020
View article titled, Abstract P5-05-03: Eribulin treatment activates type 1 IFNs to promote a gene expression signature associated with antitumor immunity
Journal Articles

Abstract 1882: Molecular context dictates the effects of eribulin on key EMT regulators: Snail and Slug

Roma Kaul, April L. Risinger, Susan L. Mooberry
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1882.
https://doi.org/10.1158/1538-7445.AM2019-1882
Published: 01 July 2019
View article titled, Abstract 1882: Molecular context dictates the effects of eribulin on key EMT regulators: Snail and Slug
Journal Articles

Abstract 2143: Identification of new molecular liabilities of a subset of triple-negative breast cancers through the investigation of englerin A

Corena V. Grant, Chase M. Carver, Shayne D. Hastings, April L. Risinger, John A. Beutler, Susan L. Mooberry
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2143.
https://doi.org/10.1158/1538-7445.AM2019-2143
Published: 01 July 2019
View article titled, Abstract 2143: Identification of new molecular liabilities of a subset of triple-negative breast cancers through the investigation of englerin A
Journal Articles

Abstract 2141: Mechanistic studies of altertoxin II: A fungal metabolite with selective activity against Ewing sarcoma

Andrew J. Robles, Wentao Dai, Robert H. Cichewicz, Susan L. Mooberry, Peter J. Houghton
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2141.
https://doi.org/10.1158/1538-7445.AM2019-2141
Published: 01 July 2019
View article titled, Abstract 2141: Mechanistic studies of altertoxin II: A fungal metabolite with selective activity against Ewing sarcoma
Journal Articles

Abstract 2908: Characteristics of triple negative breast cancer that result in sensitivity to englerin A

Corena V. Shaffer, April L. Risinger, John A. Beutler, Susan L. Mooberry
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2908.
https://doi.org/10.1158/1538-7445.AM2018-2908
Published: 01 July 2018
View article titled, Abstract 2908: Characteristics of triple negative breast cancer that result in sensitivity to englerin A
Journal Articles

Abstract 2030: Eribulin disrupts TGF-β-mediated Smad2/3-dependent transcription of EMT promoting proteins in triple negative breast cancer cells

Roma Kaul, April L. Risinger, Susan L. Mooberry
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2030.
https://doi.org/10.1158/1538-7445.AM2018-2030
Published: 01 July 2018
View article titled, Abstract 2030: Eribulin disrupts TGF-β-mediated Smad2/3-dependent transcription of EMT promoting proteins in triple negative breast cancer cells
Journal Articles

Abstract 2804: Identifying an optimal site for linker conjugation of the taccalonolides, novel microtubule stabilizing drugs

April L. Risinger, Lin Du, Antonius Ola, Robert H. Cichewicz, Susan L. Mooberry
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2804.
https://doi.org/10.1158/1538-7445.AM2018-2804
Published: 01 July 2018
View article titled, Abstract 2804: Identifying an optimal site for linker conjugation of the taccalonolides, novel microtubule stabilizing drugs
Journal Articles

Abstract 349: Eribulin induces cortical localization of E-cadherin, p120-catenin and beta-catenin in breast cancer cells

Alison D. Clark, Nicholas F. Dybdal-Hargreaves, Susan L. Mooberry
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 349.
https://doi.org/10.1158/1538-7445.AM2017-349
Published: 01 July 2017
View article titled, Abstract 349: Eribulin induces cortical localization of E-cadherin, p120-catenin and beta-catenin in breast cancer cells
Journal Articles

Abstract 4910: Eribulin rapidly impairs TGF-β signaling

Roma Kaul, April L. Risinger, Susan L. Mooberry
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4910.
https://doi.org/10.1158/1538-7445.AM2017-4910
Published: 01 July 2017
View article titled, Abstract 4910: Eribulin rapidly impairs TGF-β signaling
Journal Articles

Abstract 5105: Structure-activity relationship study of pyrrolo[2,3- d]pyrimidines as microtubule targeting antitumor agents

Aleem Gangjee, Tasdique M. Quadery, Susan L. Mooberry
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5105.
https://doi.org/10.1158/1538-7445.AM2017-5105
Published: 01 July 2017
View article titled, Abstract 5105: Structure-activity relationship study of pyrrolo[2,3- <em>d</em>]pyrimidines as microtubule targeting antitumor agents
Journal Articles

Abstract 5114: Design, synthesis, and biological evaluation of tricyclic thieno[2,3- d]pyrimidines as microtubule targeting antitumor agents

Farhana Islam, Aleem Gangjee, Xin Zhang, Xilin Zhou, Susan L. Mooberry
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5114.
https://doi.org/10.1158/1538-7445.AM2017-5114
Published: 01 July 2017
View article titled, Abstract 5114: Design, synthesis, and biological evaluation of tricyclic thieno[2,3- <em>d</em>]pyrimidines as microtubule targeting antitumor agents
Journal Articles

Abstract 5115: Establishing an experimental paradigm to study the interphase effects of microtubule targeting agents

April L. Risinger, Nicholas F. Dybdal-Hargreaves, Roma Kaul, Allison D. Clark, Susan L. Mooberry
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5115.
https://doi.org/10.1158/1538-7445.AM2017-5115
Published: 01 July 2017
View article titled, Abstract 5115: Establishing an experimental paradigm to study the interphase effects of microtubule targeting agents
Journal Articles

Abstract 3658: A novel microtubule associated RNA binding protein matrin 3 act as a tumor suppressor by regulating mitotic spindle organizing proteins in triple negative breast cancers

Panneerdoss Subbarayalu, Subapriya Rajamanickam, Suryavathi Viswanadhapalli, Benjamin C. Onyeagucha, Vijay K. Eedunuri, Nicholas Dybdal-Hargreaves, Santosh Timilsina, Hima Bansal, Sanjay Bansal, Tabrez Mohammad, Yidong Chen, John C. Herr, Susan L. Mooberry, Manjeet K. Rao
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3658.
https://doi.org/10.1158/1538-7445.AM2016-3658
Published: 15 July 2016
View article titled, Abstract 3658: A novel microtubule associated RNA binding protein matrin 3 act as a tumor suppressor by regulating mitotic spindle organizing proteins in triple negative breast cancers
Journal Articles

Abstract 4837: Design, synthesis, and biological evaluation of thieno[2,3-d] and thieno[3,2-d]pyrimidines as dual acting RTK inhibitors and microtubule targeting antitumor agents

Aleem Gangjee, Farhana Islam, Tasdique Mohammad Quadery, Susan L. Mooberry, Anja Bastian, Michael A. Ihnat
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4837.
https://doi.org/10.1158/1538-7445.AM2016-4837
Published: 15 July 2016
View article titled, Abstract 4837: Design, synthesis, and biological evaluation of thieno[2,3-d] and thieno[3,2-d]pyrimidines as dual acting RTK inhibitors and microtubule targeting antitumor agents
Journal Articles

Abstract 5545: Deguelin selectively inhibits proliferation of luminal androgen receptor (LAR) triple-negative breast cancer cells

Andrew J. Robles, Shengxin Cai, Robert H. Cichewicz, Susan L. Mooberry
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5545.
https://doi.org/10.1158/1538-7445.AM2015-5545
Published: 01 August 2015
View article titled, Abstract 5545: Deguelin selectively inhibits proliferation of luminal androgen receptor (LAR) triple-negative breast cancer cells