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Susan L. Cohn
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Journal Articles

Abstract B02: 5-Hydroxymethylcytosine profiles in circulating cell-free DNA are biomarkers of disease burden in children with neuroblastoma

Mark A. Applebaum, Erin K. Barr, Jason Karpus, Meritxell Oliva, Alexandre Chlenski, Helen R. Salwen, Emma Wilkinson, Marija Dobratic, Elizabeth A. Sokol, Barbara E. Stranger, Chuan He, Susan L. Cohn
Journal: Cancer Research
Cancer Res (2020) 80 (14_Supplement): B02.
https://doi.org/10.1158/1538-7445.PEDCA19-B02
Published: 15 July 2020
View articletitled, Abstract B02: 5-Hydroxymethylcytosine profiles in circulating cell-free DNA are biomarkers of disease burden in children with neuroblastoma
Journal Articles

Abstract PR16: Whole-genome analysis of the epigenetic mark 5-hydroxymethylcytosine reveals differential profiles in low- , intermediate- , and high-risk neuroblastomas

Mark A. Applebaum, Erin Barr, Ji Nie, Sakshi Uppal, Wei Zhang, Alexandre Chlenski, Helen Salwen, Marija Dobratic, Barbara Stranger, Lucy Godley, Chuan He, Susan L. Cohn
Journal: Cancer Research
Cancer Res (2018) 78 (19_Supplement): PR16.
https://doi.org/10.1158/1538-7445.PEDCA17-PR16
Published: 01 October 2018
View articletitled, Abstract PR16: Whole-genome analysis of the epigenetic mark 5-hydroxymethylcytosine reveals differential profiles in low- , intermediate- , and high-risk neuroblastomas
Journal Articles

Abstract A01: Evaluation of hypoxia adaptation in neuroblastoma identifies reproducible transcriptional and phenotypic responses

Mark A. Aplebaum, Aashish Jha, Alexandre Chlenski, Christopher Mariani, Clara Kao, Mildred Nelson, Kyle Hernandez, Helen Salwen, Marija Dobratic, Kevin White, Barbara Stranger, Susan L. Cohn
Journal: Cancer Research
Cancer Res (2016) 76 (5_Supplement): A01.
https://doi.org/10.1158/1538-7445.PEDCA15-A01
Published: 04 April 2016
View articletitled, Abstract A01: Evaluation of hypoxia adaptation in neuroblastoma identifies reproducible transcriptional and phenotypic responses
Journal Articles

Abstract A2-55: Identification of evolutionarily conserved hypoxia-induced genomic pathways responsible for aggressive neuroblastoma phenotypes

Mark A. Applebaum, Aashish R. Jha, Alexandre Chlenski, Kyle Hernandez, Christopher J. Mariani, Barbara E. Stranger, Susan L. Cohn
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_1): A2-55.
https://doi.org/10.1158/1538-7445.TRANSCAGEN-A2-55
Published: 15 November 2015
View articletitled, Abstract A2-55: Identification of evolutionarily conserved hypoxia-induced genomic pathways responsible for aggressive neuroblastoma phenotypes
Journal Articles

Abstract B1-15: Identification of evolutionarily conserved hypoxia-induced genomic pathways responsible for aggressive neuroblastoma phenotypes

Mark A. Aplebaum, Aashish R. Jha, Alexandre Chlenski, Kyle Hernandez, Christopher J. Mariani, Barbara E. Stranger, Susan L. Cohn
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_2): B1-15.
https://doi.org/10.1158/1538-7445.COMPSYSBIO-B1-15
Published: 15 November 2015
View articletitled, Abstract B1-15: Identification of evolutionarily conserved hypoxia-induced genomic pathways responsible for aggressive neuroblastoma phenotypes
Journal Articles

Abstract B40: MYCN/MYC protein expression in high-MKI (Mitosis-Karyorrhexis Index) neuroblastomas: A report from the Children's Oncology Group

Larry L. Wang, Risa Teshiba, Lejian He, Arlene Naranjo, Wendy B. London, Julie M. Gastier-Foster, Robert C. Seeger, Susan L. Cohn, John M. Maris, Julie R. Park, Michael D. Hogarty, Hiroyuki Shimada
Journal: Cancer Research
Cancer Res (2014) 74 (20_Supplement): B40.
https://doi.org/10.1158/1538-7445.PEDCAN-B40
Published: 09 October 2014
View articletitled, Abstract B40: MYCN/MYC protein expression in high-MKI (Mitosis-Karyorrhexis Index) neuroblastomas: A report from the Children's Oncology Group
Journal Articles

Abstract 3607: Modulation of neuroblastoma metabolism by an extracellular chaperone SPARC

Alexandre Chlenski, Marija Dobratic, Helen R. Salwen, Mark Applebaum, Susan L. Cohn
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3607.
https://doi.org/10.1158/1538-7445.AM2014-3607
Published: 01 October 2014
View articletitled, Abstract 3607: Modulation of neuroblastoma metabolism by an extracellular chaperone SPARC
Journal Articles

Truncated DNMT3B Isoform DNMT3B7 Suppresses Growth, Induces Differentiation, and Alters DNA Methylation in Human Neuroblastoma

Kelly R. Ostler, Qiwei Yang, Timothy J. Looney, Li Zhang, Aparna Vasanthakumar, Yufeng Tian, Masha Kocherginsky, Stacey L. Raimondi, Jessica G. DeMaio, Helen R. Salwen, Song Gu, Alexandre Chlenski, Arlene Naranjo, Amy Gill, Radhika Peddinti, Bruce T. Lahn, Susan L. Cohn, Lucy A. Godley
Journal: Cancer Research
Cancer Res (2012) 72 (18): 4714–4723.
https://doi.org/10.1158/0008-5472.CAN-12-0886
Published: 16 September 2012
View articletitled, Truncated DNMT3B Isoform DNMT3B7 Suppresses Growth, Induces Differentiation, and Alters DNA Methylation in Human Neuroblastoma
Open the PDF for Truncated DNMT3B Isoform DNMT3B7 Suppresses Growth, Induces Differentiation, and Alters DNA Methylation in Human Neuroblastoma in another window
Includes: Supplementary data
Journal Articles

Abstract 2486: African ancestry is associated with high-risk disease and event-free survival in children with neuroblastoma

Navin Pinto, Eric R. Gamazon, Hae Kyung Im, Anuar Konkashbaev, Nancy J. Cox, Mary Eileen Dolan, Sharon J. Diskin, Wendy B. London, John M. Maris, Susan L. Cohn
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2486.
https://doi.org/10.1158/1538-7445.AM2012-2486
Published: 15 April 2012
View articletitled, Abstract 2486: African ancestry is associated with high-risk disease and event-free survival in children with neuroblastoma
Journal Articles

Abstract 1040: A truncated DNMT3B protein (DNMT3B7) drives DNA methylation and suppresses growth in human neuroblastoma

Kelly R. Ostler, Qiwei Yang, Aparna Vasanthakumar, Li Zhang, Timothy J. Looney, Arlene Naranjo, Helen Salwen, Masha Kocherginsky, Bruce T. Lahn, Susan L. Cohn, Lucy A. Godley
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1040.
https://doi.org/10.1158/1538-7445.AM2012-1040
Published: 15 April 2012
View articletitled, Abstract 1040: A truncated DNMT3B protein (DNMT3B7) drives DNA methylation and suppresses growth in human neuroblastoma
Journal Articles

Abstract 954: ABCC/MRP multidrug transporters contribute to neuroblastoma biology, pathogenesis and clinical outcome, independently of any role in cytotoxic drug efflux

Murray D. Norris, Michelle J. Henderson, Antonio Porro, Marcia Munoz, Nunzio Iraci, Chengyuan Xue, Jayne Murray, Claudia Flemming, Jamie Fletcher, Samuele Gherardi, Alan Kwek, Amanda Russell, Wendy B. London, Allen B. Buxton, Lesley Ashton, Alan C. Sartorelli, Susan L. Cohn, Manfred Schwab, Glenn M. Marshall, Giovanni Perini, Michelle Haber
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 954.
https://doi.org/10.1158/1538-7445.AM2011-954
Published: 15 April 2011
View articletitled, Abstract 954: ABCC/MRP multidrug transporters contribute to neuroblastoma biology, pathogenesis and clinical outcome, independently of any role in cytotoxic drug efflux
Journal Articles

Thrombospondin-1 Peptide ABT-510 Combined with Valproic Acid Is an Effective Antiangiogenesis Strategy in Neuroblastoma

Qiwei Yang, Yufeng Tian, Shuqing Liu, Rana Zeine, Alexandre Chlenski, Helen R. Salwen, Jack Henkin, Susan L. Cohn
Journal: Cancer Research
Cancer Res (2007) 67 (4): 1716–1724.
https://doi.org/10.1158/0008-5472.CAN-06-2595
Published: 16 February 2007
View articletitled, Thrombospondin-1 Peptide ABT-510 Combined with Valproic Acid Is an Effective Antiangiogenesis Strategy in Neuroblastoma
Open the PDF for Thrombospondin-1 Peptide ABT-510 Combined with Valproic Acid Is an Effective Antiangiogenesis Strategy in Neuroblastoma in another window
Includes: Supplementary data
Journal Articles

The MYCN Enigma: Significance of MYCN Expression in Neuroblastoma

Xao X. Tang, Huaqing Zhao, Bing Kung, David Y. Kim, Sakeenah L. Hicks, Susan L. Cohn, Nai-Kong Cheung, Robert C. Seeger, Audrey E. Evans, Naohiko Ikegaki
Journal: Cancer Research
Cancer Res (2006) 66 (5): 2826–2833.
https://doi.org/10.1158/0008-5472.CAN-05-0854
Published: 01 March 2006
View articletitled, The MYCN Enigma: Significance of MYCN Expression in Neuroblastoma
Open the PDF for The MYCN Enigma: Significance of MYCN Expression in Neuroblastoma in another window
Includes: Supplementary data
Journal Articles

High-level MRP1 expression predicts poor clinical outcome in a large prospective study of primary neuroblastoma

Michelle Haber, Janice Smith, Sharon B. Bordow, Susan L. Cohn, Wendy B. London, Glenn M. Marshall, Murray D. Norris
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1025.
Published: 01 May 2005
View articletitled, High-level MRP1 expression predicts poor clinical outcome in a large prospective study of primary neuroblastoma
Journal Articles

Centralized generation of continuous cell lines from neuroblastoma: The initial Children’s Oncology Group experience

Lilia E. Castro, Joanne C. Lee, Lisa Moreau, A Thomas Look, Robert C. Seeger, Wendy B. London, John M. Maris, Susan L. Cohn, C. Patrick Reynolds
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 693–694.
Published: 01 May 2005
View articletitled, Centralized generation of continuous cell lines from neuroblastoma: The initial Children’s Oncology Group experience
Journal Articles

Neuroblastoma Angiogenesis Is Inhibited with a Folded Synthetic Molecule Corresponding to the Epidermal Growth Factor-Like Module of the Follistatin Domain of SPARC

Alexandre Chlenski, Shuqing Liu, Lisa J. Baker, Qiwei Yang, Yufeng Tian, Helen R. Salwen, Susan L. Cohn
Journal: Cancer Research
Cancer Res (2004) 64 (20): 7420–7425.
https://doi.org/10.1158/0008-5472.CAN-04-2141
Published: 15 October 2004
View articletitled, Neuroblastoma Angiogenesis Is Inhibited with a Folded Synthetic Molecule Corresponding to the Epidermal Growth Factor-Like Module of the Follistatin Domain of SPARC
Open the PDF for Neuroblastoma Angiogenesis Is Inhibited with a Folded Synthetic Molecule Corresponding to the Epidermal Growth Factor-Like Module of the Follistatin Domain of SPARC in another window
Journal Articles

Methylation-Associated Silencing of the Heat Shock Protein 47 Gene in Human Neuroblastoma

Qiwei Yang, Shuqing Liu, Yufeng Tian, Chiler Hasan, Donna Kersey, Helen R. Salwen, Alexandre Chlenski, Elizabeth J. Perlman, Susan L. Cohn
Journal: Cancer Research
Cancer Res (2004) 64 (13): 4531–4538.
https://doi.org/10.1158/0008-5472.CAN-04-0956
Published: 01 July 2004
View articletitled, Methylation-Associated Silencing of the Heat Shock Protein 47 Gene in Human Neuroblastoma
Open the PDF for Methylation-Associated Silencing of the Heat Shock Protein 47 Gene in Human Neuroblastoma in another window
Journal Articles

Methylation-associated Silencing of the Thrombospondin-1 Gene in Human Neuroblastoma

Qi-Wei Yang, Shuqing Liu, Yufeng Tian, Helen R. Salwen, Alexandre Chlenski, Joanna Weinstein, Susan L. Cohn
Journal: Cancer Research
Cancer Res (2003) 63 (19): 6299–6310.
Published: 14 October 2003
View articletitled, Methylation-associated Silencing of the Thrombospondin-1 Gene in Human Neuroblastoma
Open the PDF for Methylation-associated Silencing of the Thrombospondin-1 Gene in Human Neuroblastoma in another window
Journal Articles

SPARC Is a Key Schwannian-derived Inhibitor Controlling Neuroblastoma Tumor Angiogenesis

Alexandre Chlenski, Shuqing Liu, Susan E. Crawford, Olga V. Volpert, George H. DeVries, Amy Evangelista, Qiwei Yang, Helen R. Salwen, Robert Farrer, James Bray, Susan L. Cohn
Journal: Cancer Research
Cancer Res (2002) 62 (24): 7357–7363.
Published: 15 December 2002
View articletitled, SPARC Is a Key Schwannian-derived Inhibitor Controlling Neuroblastoma Tumor Angiogenesis
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Journal Articles

Schwann Cell-conditioned Medium Inhibits Angiogenesis

Donghui Huang, J. Lynn Rutkowski, Garrett M. Brodeur, Pauline M. Chou, Janet L. Kwiatkowski, Angela Babbo, Susan L. Cohn
Journal: Cancer Research
Cancer Res (2000) 60 (21): 5966–5971.
Published: 01 November 2000
View articletitled, Schwann Cell-conditioned Medium Inhibits Angiogenesis
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