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Susan G. Hilsenbeck
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Journal Articles

Abstract CT273: Unique multicenter trial design to investigate ARTIDIS nanomechanical generated measurements for early breast lesions (ANGEL)

Karla A. Sepulveda, Ashley Roark, Sagar Dhamne, Chandandeep Nagi, Ivan Marin, Iqbal Tabish, Sara Nizzero, Mariam Gachechiladze, Tobias Appenzeller, Philipp Oertle, Marko Loparic, Susan G. Hilsenbeck, Marija Plodinec, Alastair Thompson
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT273.
https://doi.org/10.1158/1538-7445.AM2024-CT273
Published: 05 April 2024
View article titled, Abstract CT273: Unique multicenter trial design to investigate ARTIDIS nanomechanical generated measurements for early breast lesions (ANGEL)
Journal Articles

Abstract 3942: Mailed at-home self-sampling for HPV testing increases screening participation among under-screened patients in a U.S. safety net health system: Results of the PRESTIS trial

Jane R. Montealegre, Elizabeth Y. Chiao, Matthew L. Anderson, Susan G. Hilsenbeck, Shaun Bulsara, Susan L. Parker, Maria Daheri, Trisha L. Amboree, Kathleen M. Schmeler, Maria L. Jibaja-Weiss, Mohammad Zare, Ashish A. Deshmukh, Michael E. Scheurer
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3942.
https://doi.org/10.1158/1538-7445.AM2024-3942
Published: 22 March 2024
View article titled, Abstract 3942: Mailed at-home self-sampling for HPV testing increases screening participation among under-screened patients in a U.S. safety net health system: Results of the PRESTIS trial
Journal Articles

Abstract P2-23-01: Patient-derived xenografts allow deconvolution of single agent and combination chemotherapy responses in triple-negative breast cancer

Jonathan T. Lei, Chen Huang, Ramakrishnan R. Srinivasan, Suhas Vasaikar, Lacey E. Dobrolecki, Alaina N. Lewis, Na Zhao, Jin Cao, Susan G. Hilsenbeck, C. Kent Osborne, Mothaffar Rimawi, Matthew J. Ellis, Varduhi Petrosyan, Alexander B. Saltzman, Anna Malovannaya, John D. Landua, Bo Wen, Antrix Jain, Gerburg M. Wulf, Shunqiang Li, Daniel C. Kraushaar, Tao Wang, Xi Chen, Gloria V. Echeverria, Meenakshi Anurag, Bing Zhang, Michael T. Lewis
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P2-23-01.
https://doi.org/10.1158/1538-7445.SABCS22-P2-23-01
Published: 01 March 2023
View article titled, Abstract P2-23-01: Patient-derived xenografts allow deconvolution of single agent and combination chemotherapy responses in triple-negative breast cancer
Journal Articles

Abstract P5-07-01: Proteogenomic analysis of differential chemotherapy responses in patient-derived xenografts of triple-negative breast cancer

Jonathan T Lei, Chen Huang, Ramakrishnan R Srinivasan, Suhas Vasaikar, Lacey E Dobrolecki, Alaina N Lewis, Christina Sallas, Susan G Hilsenbeck, C. Kent Osborne, Mothaffar F Rimawi, Matthew J Ellis, Varduhi Petrosyan, Alexander B Saltzman, Anna Malovannaya, Gerburg Wulf, Daniel C Kraushaar, Tao Wang, Xi Chen, Gloria V Echeverria, Meenakshi Anurag, Bing Zhang, Michael T Lewis
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P5-07-01.
https://doi.org/10.1158/1538-7445.SABCS21-P5-07-01
Published: 15 February 2022
View article titled, Abstract P5-07-01: Proteogenomic analysis of differential chemotherapy responses in patient-derived xenografts of triple-negative breast cancer
Journal Articles

Abstract P5-01-03: Mouse-intraductal (MIND): An in vivo model for studying the underlying mechanisms of DCIS malignancy

Aditi Rastogi, Jerome Lin, Yan Hong, Darlene Limback, Hanan S. Elsarraj, Haleigh Harper, Haley Haines, Hayley Hansford, Michael Ricci, Carolyn Kaufman, Emily Wedlock, Mingchu Xu, Jianhua Zhang, Lisa May, Terri Cusick, Marc Inciardi, Mark Redick, Jason Gatewood, Onalisa Winblad, Allison Aripoli, Ashley Huppe, Christa Balanoff, Jamie Wagner, Amanda Amin, Kelsey E. Larson, Lawrence Ricci, Ossama Tawfik, Hana Razek, Ruby O Meierotto, Rashna Madan, Andrew K. Godwin, Jeffrey Thompson, Susan G. Hilsenbeck, Andy Futreal, Alastair Thompson, E. Shelley Hwang, Fang Fan, Nicholas Navin, Fariba Behbod, Grand Challenge PRECISION Consortium
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P5-01-03.
https://doi.org/10.1158/1538-7445.SABCS21-P5-01-03
Published: 15 February 2022
View article titled, Abstract P5-01-03: Mouse-intraductal (MIND): An <em>in vivo</em> model for studying the underlying mechanisms of DCIS malignancy
Journal Articles

A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis

Fei Yue, Weiyu Jiang, Amy T. Ku, Adelaide I.J. Young, Weijie Zhang, Eric P. Souto, Yankun Gao, Zihan Yu, Yi Wang, Chad J. Creighton, Chandandeep Nagi, Tao Wang, Susan G. Hilsenbeck, Xin-Hua Feng, Shixia Huang, Cristian Coarfa, Xiang H.-F. Zhang, Qingyun Liu, Xia Lin, Yi Li
Journal: Cancer Research
Cancer Res (2021) 81 (17): 4441–4454.
https://doi.org/10.1158/0008-5472.CAN-21-1112
Published: 01 September 2021
View article titled, A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis
Open the PDF for A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 2992: Proteogenomic characterization of triple-negative breast cancer patient-derived xenografts reveals molecular correlates of differential chemotherapy response and potential therapeutic targets to overcome resistance

Jonathan T. Lei, Chen Huang, Ramakrishnan R. Srinivasan, Suhas Vasaikar, Lacey E. Dobrolecki, Alaina N. Lewis, Christina Sallas, Susan G. Hilsenbeck, C Kent Osborne, Mothaffar F. Rimawi, Matthew J. Ellis, Varduhi Petrosyan, Alexander B. Saltzman, Anna Malovannaya, Gerburg Wulf, Daniel C. Kraushaar, Tao Wang, Gloria V. Echeverria, Bing Zhang, Michael T. Lewis
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2992.
https://doi.org/10.1158/1538-7445.AM2021-2992
Published: 01 July 2021
View article titled, Abstract 2992: Proteogenomic characterization of triple-negative breast cancer patient-derived xenografts reveals molecular correlates of differential chemotherapy response and potential therapeutic targets to overcome resistance
Journal Articles

Abstract GS3-08: Multiplatform analysis of matched primary and metastatic breast tumors from the AURORA US Network

Tari A King, Minetta C Liu, Marni B McClure, Toshinori Hinoue, Benjamin J Kelly, Chad J Creighton, Jay Bowen, Kristen Leraas, Robyn T Burns, Sara Coppens, Salma Rezk, Amy L Garrett, Justin M Balko, Joel S Parker, Ben H Park, Ian Krop, Carey Anders, Katherine A Hoadley, Julie Gastier-Foster, Mothaffar F Rimawi, Rita Nanda, Nancy U Lin, Claudine Isaacs, P. Kelly Marcom, Anna Maria Storniolo, Fergus J Couch, Elaine R Mardis, Adrian V Lee, Uma Chandran, Peter W Laird, Susan G Hilsenbeck, Larry Norton, Andrea L Richardson, W. Fraser Symmans, Lisa A Carey, Antonio C Wolff, Nancy E Davidson, Charles M Perou, the AURORA US Network
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): GS3-08.
https://doi.org/10.1158/1538-7445.SABCS19-GS3-08
Published: 15 February 2020
View article titled, Abstract GS3-08: Multiplatform analysis of matched primary and metastatic breast tumors from the AURORA US Network
Journal Articles

Abstract 4757: Targeting the mevalonate pathway in HER2+breast cancer to overcome resistance and enhance anti-HER2 therapy efficacy

Vidyalakshmi Sethunath, Huizhong Hu, Carmine DeAngelis, Jamunarani Veeraraghavan, Lanfang Qin, Martin Shea, Tamika Mitchell, Sarmistha Nanda, Resel Pereira, Susan G. Hilsenbeck, Mothaffar F. Rimawi, Kent C. Osborne, Rachel Schiff
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4757.
https://doi.org/10.1158/1538-7445.AM2019-4757
Published: 01 July 2019
View article titled, Abstract 4757: Targeting the mevalonate pathway in HER2+breast cancer to overcome resistance and enhance anti-HER2 therapy efficacy
Journal Articles

Abstract 4827: The therapeutic superiority of neratinib in combination with trastuzumab compared to pertuzumab plus trastuzumab in HER2-positive in vivo breast cancer models

Jamunarani Veeraraghavan, Vidyalakshmi Sethunath, Martin J. Shea, Tamika Mitchell, Resel Pereira, Lanfang Qin, Sarmistha Nanda, Carmine De Angelis, Kristina Goutsouliak, Irmina Diala, Alshad S. Lalani, Sepideh Mehravaran, Susan G. Hilsenbeck, Chandandeep Nagi, Carolina Gutierrez, Mothaffar F. Rimawi, C. Kent Osborne, Rachel Schiff
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4827.
https://doi.org/10.1158/1538-7445.AM2019-4827
Published: 01 July 2019
View article titled, Abstract 4827: The therapeutic superiority of neratinib in combination with trastuzumab compared to pertuzumab plus trastuzumab in HER2-positive <em>in vivo</em> breast cancer models
Journal Articles

Mammary Precancerous Stem and Non-Stem Cells Evolve into Cancers of Distinct Subtypes

Wen Bu, Zhenyu Liu, Weiyu Jiang, Chandandeep Nagi, Shixia Huang, Dean P. Edwards, Eunji Jo, Qianxing Mo, Chad J. Creighton, Susan G. Hilsenbeck, Andrew D. Leavitt, Michael T. Lewis, Stephen T. C. Wong, Yi Li
Journal: Cancer Research
Cancer Res (2019) 79 (1): 61–71.
https://doi.org/10.1158/0008-5472.CAN-18-1087
Published: 02 January 2019
View article titled, Mammary Precancerous Stem and Non-Stem Cells Evolve into Cancers of Distinct Subtypes
Open the PDF for Mammary Precancerous Stem and Non-Stem Cells Evolve into Cancers of Distinct Subtypes in another window
Includes: Supplementary data
Journal Articles

Tenascin-C and Integrin α9 Mediate Interactions of Prostate Cancer with the Bone Microenvironment

Rebeca San Martin, Ravi Pathak, Antrix Jain, Sung Yun Jung, Susan G. Hilsenbeck, María C. Piña-Barba, Andrew G. Sikora, Kenneth J. Pienta, David R. Rowley
Journal: Cancer Research
Cancer Res (2017) 77 (21): 5977–5988.
https://doi.org/10.1158/0008-5472.CAN-17-0064
Published: 31 October 2017
View article titled, Tenascin-C and Integrin α9 Mediate Interactions of Prostate Cancer with the Bone Microenvironment
Open the PDF for Tenascin-C and Integrin α9 Mediate Interactions of Prostate Cancer with the Bone Microenvironment in another window
Includes: Supplementary data
Journal Articles

Abstract 1223: Evaluation of the dual p38/NLK kinase inhibitor as potential new therapeutic agent for tamoxifen-resistant breast cancer

XIAN WANG, Xixi Cao, Jamunarani Veeraraghavan, Lanfang Qin, Jin-Ah Kim, Ying Tan, Susan G. Hilsenbeck, Rachel Schiff, Xiaosong Wang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1223.
https://doi.org/10.1158/1538-7445.AM2017-1223
Published: 01 July 2017
View article titled, Abstract 1223: Evaluation of the dual p38/NLK kinase inhibitor as potential new therapeutic agent for tamoxifen-resistant breast cancer
Journal Articles

Abstract A34: CELF1 is a central node in post-transcriptional regulatory programs underlying EMT and metastasis in breast epithelial cells

Arindam Chaudhury, Shebna Cheema, Joseph M. Fachini, Natee Kongchan, Guojun Lu, Lukas M. Simon, Tao Wang, Sufeng Mao, Daniel G. Rosen, Michael M. Ittmann, Susan G. Hilsenbeck, Chad A. Shaw, Joel R. Neilson
Journal: Cancer Research
Cancer Res (2017) 77 (6_Supplement): A34.
https://doi.org/10.1158/1538-7445.Transcontrol16-A34
Published: 14 March 2017
View article titled, Abstract A34: CELF1 is a central node in post-transcriptional regulatory programs underlying EMT and metastasis in breast epithelial cells
Journal Articles

Abstract 5193: Identification of molecular predictors of differential chemotherapy response using patient-derived xenografts

Michael T. Lewis, Lacey E. Dobrolecki, Susan G. Hilsenbeck, Lukas M. Simon, Chad A. Shaw
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5193.
https://doi.org/10.1158/1538-7445.AM2016-5193
Published: 15 July 2016
View article titled, Abstract 5193: Identification of molecular predictors of differential chemotherapy response using patient-derived xenografts
Journal Articles

Abstract 3470: Obesity and metformin alter progression of triple negative breast cancer

Laura Camacho, Lei Xue, Lacey Dobrolecki, Susan G. Hilsenbeck, Chandandeep Nagi, Nagireddy Putluri, Michael T. Lewis, Arun Sreekumar, Sao Jiralerspong
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3470.
https://doi.org/10.1158/1538-7445.AM2016-3470
Published: 15 July 2016
View article titled, Abstract 3470: Obesity and metformin alter progression of triple negative breast cancer
Journal Articles

Abstract 2913: The SOX11 transcription factor is critical for basal-like breast cancer growth and migration and is associated with poor survival

Jonathan Shepherd, Abhijit Mazumdar, Anna Tsimelzon, Susan G. Hilsenbeck, Powel H. Brown
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2913.
https://doi.org/10.1158/1538-7445.AM2016-2913
Published: 15 July 2016
View article titled, Abstract 2913: The SOX11 transcription factor is critical for basal-like breast cancer growth and migration and is associated with poor survival
Journal Articles

Abstract B58: CELF1 is a central node in post-transcriptional regulatory programs underlying EMT and metastasis in breast epithelial cells

Arindam Chaudhury, Natee Kongchan, Joseph M. Fachini, Lukas M. Simon, Tao Wang, Sufeng Mao, Daniel G. Rosen, Michael M. Ittmann, Susan G. Hilsenbeck, Chad A. Shaw, Joel R. Neilson
Journal: Cancer Research
Cancer Res (2016) 76 (7_Supplement): B58.
https://doi.org/10.1158/1538-7445.TUMMET15-B58
Published: 26 May 2016
View article titled, Abstract B58: CELF1 is a central node in post-transcriptional regulatory programs underlying EMT and metastasis in breast epithelial cells
Journal Articles

Phosphatase PTP4A3 Promotes Triple-Negative Breast Cancer Growth and Predicts Poor Patient Survival

Petra den Hollander, Kathryn Rawls, Anna Tsimelzon, Jonathan Shepherd, Abhijit Mazumdar, Jamal Hill, Suzanne A.W. Fuqua, Jenny C. Chang, C. Kent Osborne, Susan G. Hilsenbeck, Gordon B. Mills, Powel H. Brown
Journal: Cancer Research
Cancer Res (2016) 76 (7): 1942–1953.
https://doi.org/10.1158/0008-5472.CAN-14-0673
Published: 31 March 2016
View article titled, Phosphatase PTP4A3 Promotes Triple-Negative Breast Cancer Growth and Predicts Poor Patient Survival
Open the PDF for Phosphatase PTP4A3 Promotes Triple-Negative Breast Cancer Growth and Predicts Poor Patient Survival in another window
Includes: Supplementary data
Journal Articles

HER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes

Bryan C. Nikolai, Rainer B. Lanz, Brian York, Subhamoy Dasgupta, Nicholas Mitsiades, Chad J. Creighton, Anna Tsimelzon, Susan G. Hilsenbeck, David M. Lonard, Carolyn L. Smith, Bert W. O'Malley
Journal: Cancer Research
Cancer Res (2016) 76 (6): 1463–1475.
https://doi.org/10.1158/0008-5472.CAN-15-2383
Published: 14 March 2016
View article titled, HER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes
Open the PDF for HER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes in another window
Includes: Supplementary data