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Susan D. Spencer
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Journal Articles

Abstract 4494: A clinical candidate anti-mesothelin-MMAE antibody-drug conjugate (ADC) for therapy of mesothelin-expressing cancers

Free
Suzie J. Scales, Nidhi Gupta, Glenn Pacheco, Ron Firestein, Dorothy M. French, Josefa Chuh, Yin Zhang, Leanne Berry, Jenny Bostrom, Elizabeth Luis, Aimee Fourie O'Donohue, Katherine R. Kozak, Sarajane Ross, Mark S. Dennis, Jay Tibbitts, Susan D. Spencer
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4494.
https://doi.org/10.1158/1538-7445.AM2014-4494
Published: 01 October 2014
View articletitled, Abstract 4494: A clinical candidate anti-mesothelin-MMAE antibody-drug conjugate (ADC) for therapy of mesothelin-expressing cancers
Journal Articles

Abstract 4502: Nonclinical characterization and tolerability of a surrogate anti-mesothelin-MMAE antibody-drug conjugate

Free
Nidhi Gupta, Willy A. Solis, Reina N. Fuji, Amy Oldendorp, Glenn Pacheco, Elizabeth Luis, Josefa Chuh, Dorothy M. French, Elizabeth Drake, Mark S. Dennis, Katherine R. Kozak, Sarajane Ross, Jay Tibbitts, Susan D. Spencer, Suzie J. Scales
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4502.
https://doi.org/10.1158/1538-7445.AM2014-4502
Published: 01 October 2014
View articletitled, Abstract 4502: Nonclinical characterization and tolerability of a surrogate anti-mesothelin-MMAE antibody-drug conjugate
Journal Articles

Abstract 4396: Conjugation site modulates the stability and biological activity of antibody drug conjugates

Free
Ben-Quan Shen, Keyang Xu, Luna Liu, Kathryn Parsons, Sunil Bhakta, Helga Raab, 20 more Genentech Authors, Kelly Flagella, Susan D. Spencer, Surinder Kaur, Richard H. Scheller, Mark X. Sliwkowski, Paul Polakis, Jagath Reddy Junutula
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4396.
https://doi.org/10.1158/1538-7445.AM10-4396
Published: 15 April 2010
View articletitled, Abstract 4396: Conjugation site modulates the stability and biological activity of antibody drug conjugates
Journal Articles

Antibody-Drug Conjugates for the Treatment of Non–Hodgkin's Lymphoma: Target and Linker-Drug Selection

Available to Purchase
Andrew G. Polson, Jill Calemine-Fenaux, Pamela Chan, Wesley Chang, Erin Christensen, Suzanna Clark, Frederic J. de Sauvage, Dan Eaton, Kristi Elkins, J. Michael Elliott, Gretchen Frantz, Reina N. Fuji, Alane Gray, Kristin Harden, Gladys S. Ingle, Noelyn M. Kljavin, Hartmut Koeppen, Christopher Nelson, Saileta Prabhu, Helga Raab, Sarajane Ross, Jean-Philippe Stephan, Suzie J. Scales, Susan D. Spencer, Richard Vandlen, Bernd Wranik, Shang-Fan Yu, Bing Zheng, Allen Ebens
Journal: Cancer Research
Cancer Res (2009) 69 (6): 2358–2364.
https://doi.org/10.1158/0008-5472.CAN-08-2250
Published: 17 March 2009
View articletitled, Antibody-Drug Conjugates for the Treatment of Non–Hodgkin's Lymphoma: Target and Linker-Drug Selection
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Includes: Supplementary data
Journal Articles

Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody–Cytotoxic Drug Conjugate

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Gail D. Lewis Phillips, Guangmin Li, Debra L. Dugger, Lisa M. Crocker, Kathryn L. Parsons, Elaine Mai, Walter A. Blättler, John M. Lambert, Ravi V.J. Chari, Robert J. Lutz, Wai Lee T. Wong, Frederic S. Jacobson, Hartmut Koeppen, Ralph H. Schwall, Sara R. Kenkare-Mitra, Susan D. Spencer, Mark X. Sliwkowski
Journal: Cancer Research
Cancer Res (2008) 68 (22): 9280–9290.
https://doi.org/10.1158/0008-5472.CAN-08-1776
Published: 14 November 2008
View articletitled, Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody–Cytotoxic Drug Conjugate
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Journal Articles

Prostate Stem Cell Antigen as Therapy Target: Tissue Expression and in Vivo Efficacy of an Immunoconjugate

Available to Purchase
Sarajane Ross, Susan D. Spencer, Ilona Holcomb, Christine Tan, JoAnne Hongo, Brigitte Devaux, Linda Rangell, Gilbert A. Keller, Peter Schow, Rita M. Steeves, Robert J. Lutz, Gretchen Frantz, Kenneth Hillan, Franklin Peale, Patti Tobin, David Eberhard, Mark A. Rubin, Laurence A. Lasky, Hartmut Koeppen
Journal: Cancer Research
Cancer Res (2002) 62 (9): 2546–2553.
Published: 01 May 2002
View articletitled, Prostate Stem Cell Antigen as Therapy Target: Tissue Expression and in Vivo Efficacy of an Immunoconjugate
Open the PDF for Prostate Stem Cell Antigen as Therapy Target: Tissue Expression and in Vivo Efficacy of an Immunoconjugate in another window