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Sunil R. Hingorani
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Journal Articles

Abstract PR12: Targeting CDK7/9 in basal pancreatic cancer

Sita Kugel, Nithya Kartha, Jessica E. Gianopulos, Zach Schrank, Sarah M. Cavender, Stephanie Dobersch, Notta Faiyaz, David H. Price, Andrew C. Hsieh, Sunil R. Hingorani
Journal: Cancer Research
Cancer Res (2024) 84 (2_Supplement): PR12.
https://doi.org/10.1158/1538-7445.PANCA2023-PR12
Published: 16 January 2024
View article titled, Abstract PR12: Targeting CDK7/9 in basal pancreatic cancer
Journal Articles

Abstract A056: Epithelial hyaluronan synthase 2 expression promotes pancreas cancer metastasis

Bo Tu, Heather Wright T. Wright, Christopher C. Dufort, Martin C. Whittle, Libing Feng, Shelley M. Thorsen, Sunil R. Hingorani
Journal: Cancer Research
Cancer Res (2022) 82 (22_Supplement): A056.
https://doi.org/10.1158/1538-7445.PANCA22-A056
Published: 15 November 2022
View article titled, Abstract A056: Epithelial hyaluronan synthase 2 expression promotes pancreas cancer metastasis
Journal Articles

Abstract IA019: Stromal-epithelial co-evolution and complicity in pancreas cancer

Sunil R. Hingorani
Journal: Cancer Research
Cancer Res (2022) 82 (22_Supplement): IA019.
https://doi.org/10.1158/1538-7445.PANCA22-IA019
Published: 15 November 2022
View article titled, Abstract IA019: Stromal-epithelial co-evolution and complicity in pancreas cancer
Journal Articles

Abstract PO-076: Murine adapted FOLFIRINOX for standard-of-care in KPC mice

Martin C. Whittle, Aditi Palkar, Rachael Fasnacht, James Yan, Borith Kheng, Kianna Sinfuego, Shelley Thorsen, Sunil R. Hingorani
Journal: Cancer Research
Cancer Res (2021) 81 (22_Supplement): PO-076.
https://doi.org/10.1158/1538-7445.PANCA21-PO-076
Published: 15 November 2021
View article titled, Abstract PO-076: Murine adapted FOLFIRINOX for standard-of-care in KPC mice
Journal Articles

Abstract PO-105: Overcoming stromal barriers in PDA with a novel polymeric Toll-like receptor agonist

Christopher C. DuFort, Ciana L. Lopez, Martin C. Whittle, Vladimir Vlaskin, Aditi Vadodkar, Selvi Srinivasan, Patrick S. Stayton, Sunil R. Hingorani
Journal: Cancer Research
Cancer Res (2021) 81 (22_Supplement): PO-105.
https://doi.org/10.1158/1538-7445.PANCA21-PO-105
Published: 15 November 2021
View article titled, Abstract PO-105: Overcoming stromal barriers in PDA with a novel polymeric Toll-like receptor agonist
Journal Articles

Abstract I11: Targeting pancreatic cancer with TCR-engineered T cells

Philip D. Greenberg, Kristin G. Anderson, Dan Egan, Sunil R. Hingorani, Luigi Nezi, Teresa Manzo, Shannon K. Oda, Kelly G. Paulson, Rachel Perret, Leah Schmidt, Tom M. Schmitt, Ingunn M. Stromnes, Aude G. Chapuis
Journal: Cancer Research
Cancer Res (2019) 79 (24_Supplement): I11.
https://doi.org/10.1158/1538-7445.PANCA19-I11
Published: 13 December 2019
View article titled, Abstract I11: Targeting pancreatic cancer with TCR-engineered T cells
Journal Articles

Abstract A80: Targeted depletion of extracellular matrix components in PDA eases barriers to treatment

Markus A. Carlson, Christopher C. Dufort, Kathleen E. DelGiorno, J. Scott Brockenbrough, Ashley M. Dotson, Sunil R. Hingorani
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): A80.
https://doi.org/10.1158/1538-7445.PANCA16-A80
Published: 14 December 2016
View article titled, Abstract A80: Targeted depletion of extracellular matrix components in PDA eases barriers to treatment
Journal Articles

Abstract A66: Runx3 drives metastatic programs in pancreas cancer

Martin C. Whittle, Libing Feng, Ashley Dotson, Fiona Pakiam, Sunil R. Hingorani
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): A66.
https://doi.org/10.1158/1538-7445.PANCA16-A66
Published: 14 December 2016
View article titled, Abstract A66: Runx3 drives metastatic programs in pancreas cancer
Journal Articles

Pulsed High-Intensity Focused Ultrasound Enhances Delivery of Doxorubicin in a Preclinical Model of Pancreatic Cancer

Tong Li, Yak-Nam Wang, Tatiana D. Khokhlova, Samantha D'Andrea, Frank Starr, Hong Chen, Jeannine S. McCune, Linda J. Risler, Afshin Mashadi-Hossein, Sunil R. Hingorani, Amy Chang, Joo Ha Hwang
Journal: Cancer Research
Cancer Res (2015) 75 (18): 3738–3746.
https://doi.org/10.1158/0008-5472.CAN-15-0296
Published: 14 September 2015
View article titled, Pulsed High-Intensity Focused Ultrasound Enhances Delivery of Doxorubicin in a Preclinical Model of Pancreatic Cancer
Open the PDF for Pulsed High-Intensity Focused Ultrasound Enhances Delivery of Doxorubicin in a Preclinical Model of Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract SY31-03: Employing TCRs in engineered T cells to develop therapeutic reagents for effectively targeting malignancies

Philip D. Greenberg, Tom M. Schmitt, Andrea Schietinger, Ingunn M. Stromnes, Sunil R. Hingorani, Shannon K. Oda, Rachel Perret, Kristin G. Anderson, Merav Bar, Aude G. Chapuis
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): SY31-03.
https://doi.org/10.1158/1538-7445.AM2015-SY31-03
Published: 01 August 2015
View article titled, Abstract SY31-03: Employing TCRs in engineered T cells to develop therapeutic reagents for effectively targeting malignancies
Journal Articles

Abstract A67: Defining signaling pathways governing metastatic potential in pancreas cancer

Martin C. Whittle, Markus Carlson, Sunil R. Hingorani
Journal: Cancer Research
Cancer Res (2015) 75 (13_Supplement): A67.
https://doi.org/10.1158/1538-7445.PANCA2014-A67
Published: 30 June 2015
View article titled, Abstract A67: Defining signaling pathways governing metastatic potential in pancreas cancer
Journal Articles

Abstract A92: Murine clinical trials program

J. Scott Brockenbrough, Libing Feng, Ingunn M. Stromnes, Kathleen E. DelGiorno, Martin C. Whittle, Carlos Cuevas, Ashley M. Dotson, Joseph S. Ryan, Shelley M. Thorsen, Sunil R. Hingorani
Journal: Cancer Research
Cancer Res (2015) 75 (13_Supplement): A92.
https://doi.org/10.1158/1538-7445.PANCA2014-A92
Published: 30 June 2015
View article titled, Abstract A92: Murine clinical trials program
Journal Articles

Abstract B05: Assessing and removing biophysical barriers to treatment

Kathleen E. DelGiorno, Markus Carlson, Paolo P. Provenzano, Scott Brockenbough, Sunil R. Hingorani
Journal: Cancer Research
Cancer Res (2015) 75 (13_Supplement): B05.
https://doi.org/10.1158/1538-7445.PANCA2014-B05
Published: 30 June 2015
View article titled, Abstract B05: Assessing and removing biophysical barriers to treatment
Journal Articles

Abstract B74: Minimally invasive ablative therapy for mucinous cystic neoplasms (MCN) in a genetically engineered mouse model

Carlos Cuevas, Ashley M. Dotson, Sunil R. Hingorani
Journal: Cancer Research
Cancer Res (2015) 75 (13_Supplement): B74.
https://doi.org/10.1158/1538-7445.PANCA2014-B74
Published: 30 June 2015
View article titled, Abstract B74: Minimally invasive ablative therapy for mucinous cystic neoplasms (MCN) in a genetically engineered mouse model
Journal Articles

Abstract PR10: Re-engineering immunity to treat pancreas cancer

Ingunn M. Stromnes, Scott Brockenbrough, Thomas M. Schmitt, Jennifer D. Hotes, Markus A. Carlson, Carlos Cuevos, Philip D. Greenberg, Sunil R. Hingorani
Journal: Cancer Research
Cancer Res (2015) 75 (13_Supplement): PR10.
https://doi.org/10.1158/1538-7445.PANCA2014-PR10
Published: 30 June 2015
View article titled, Abstract PR10: Re-engineering immunity to treat pancreas cancer
Journal Articles

Hypoxia Triggers Hedgehog-Mediated Tumor–Stromal Interactions in Pancreatic Cancer

Taly R. Spivak-Kroizman, Galen Hostetter, Richard Posner, Meraj Aziz, Chengcheng Hu, Michael J. Demeure, Daniel Von Hoff, Sunil R. Hingorani, Timothy B. Palculict, Julie Izzo, Galina M. Kiriakova, Mena Abdelmelek, Geoffrey Bartholomeusz, Brian P. James, Garth Powis
Journal: Cancer Research
Series: Author Choice
Cancer Res (2013) 73 (11): 3235–3247.
https://doi.org/10.1158/0008-5472.CAN-11-1433
Published: 30 May 2013
View article titled, Hypoxia Triggers Hedgehog-Mediated Tumor–Stromal Interactions in Pancreatic Cancer
Open the PDF for Hypoxia Triggers Hedgehog-Mediated Tumor–Stromal Interactions in Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 1487: Modulation of pancreas cancer invasion and metastasis by SMAD4/DPC4 signaling

Vikas K. Goel, P G. Rani, Kamel Izeradjene, Philamer Calses, Catherine Gard, Paolo P. Provenzano, Amy E. Chang, Hsin-Pin Lin, Sunil R. Hingorani
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1487.
https://doi.org/10.1158/1538-7445.AM2011-1487
Published: 15 April 2011
View article titled, Abstract 1487: Modulation of pancreas cancer invasion and metastasis by SMAD4/DPC4 signaling
Journal Articles

Dynamics of the Immune Reaction to Pancreatic Cancer from Inception to Invasion

Carolyn E. Clark, Sunil R. Hingorani, Rosemarie Mick, Chelsea Combs, David A. Tuveson, Robert H. Vonderheide
Journal: Cancer Research
Cancer Res (2007) 67 (19): 9518–9527.
https://doi.org/10.1158/0008-5472.CAN-07-0175
Published: 01 October 2007
View article titled, Dynamics of the Immune Reaction to Pancreatic Cancer from Inception to Invasion
Open the PDF for Dynamics of the Immune Reaction to Pancreatic Cancer from Inception to Invasion in another window
Includes: Supplementary data
Journal Articles

The RON Receptor Tyrosine Kinase Mediates Oncogenic Phenotypes in Pancreatic Cancer Cells and Is Increasingly Expressed during Pancreatic Cancer Progression

Ryan M. Thomas, Kenya Toney, Cecilia Fenoglio-Preiser, Monica P. Revelo-Penafiel, Sunil R. Hingorani, David A. Tuveson, Susan E. Waltz, Andrew M. Lowy
Journal: Cancer Research
Cancer Res (2007) 67 (13): 6075–6082.
https://doi.org/10.1158/0008-5472.CAN-06-4128
Published: 06 July 2007
View article titled, The RON Receptor Tyrosine Kinase Mediates Oncogenic Phenotypes in Pancreatic Cancer Cells and Is Increasingly Expressed during Pancreatic Cancer Progression
Open the PDF for The RON Receptor Tyrosine Kinase Mediates Oncogenic Phenotypes in Pancreatic Cancer Cells and Is Increasingly Expressed during Pancreatic Cancer Progression in another window
Journal Articles

Leukocytic infiltration of pancreatic cancer in the mouse is dominated by suppressor cells even at the earliest stages of tumorigenesis

Carolyn E. Clark, Sunil R. Hingorani, Chelsea Combs, David A. Tuveson, Robert H. Vonderheide
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1120.
Published: 15 April 2006
View article titled, Leukocytic infiltration of pancreatic cancer in the mouse is dominated by suppressor cells even at the earliest stages of tumorigenesis