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Journal Articles

Abstract 804: Antitumor activity of the potent and novel FLT3 inhibitor HM43239 in acute myeloid leukemia

Miyoung Lee, Young Eun Ha, Mi Jin Moon, Joo-Yun Byun, HyunKyung Yu, SeokJong Kang, JaeHo Lee, Kyuhang Lee, Eunkyung Kim, Eunyoung Kim, Ho Jeong Lee, YoungHoon Kim, YoungGil Ahn, KweeHyun Suh, Sun-Jin Kim

Cancer Res (2018) 78 (13_Supplement): 804.

https://doi.org/10.1158/1538-7445.AM2018-804

Published: 01 July 2018

View article titled, Abstract 804: Antitumor activity of the potent and novel FLT3 inhibitor HM43239 in acute myeloid leukemia

Journal Articles

Abstract 4780: A novel, potent and selective FGFR4 inhibitor, HM81422 in hepatocellular carcinoma with FGFR4-driven pathway activation

JaeHo Lee, Hyunjeong Kang, Kyounghwa Koo, Youngeun Ha, Sun Young Lim, Joo-Yun Byun, Hyunkyung Yu, Taehun Song, Moonsub Lee, Seung Hyun Jung, Taewoo Kim, Hyojeong Bang, Eunyoung Kim, Jahoon Kang, Ho Jeong Lee, YoungHoon Kim, YoungGil Ahn, KweeHyun Suh, Sun-Jin Kim

Cancer Res (2018) 78 (13_Supplement): 4780.

https://doi.org/10.1158/1538-7445.AM2018-4780

Published: 01 July 2018

View article titled, Abstract 4780: A novel, potent and selective FGFR4 inhibitor, HM81422 in hepatocellular carcinoma with FGFR4-driven pathway activation

Journal Articles

Abstract 4871: Antitumor activity of novel reversible LSD1 inhibitor, HM97211 in preclinical models of SCLC

InHwan Bae, JiSook Kim, ChangHee Park, Hyeongki Kim, Namgoong Gwangmog, Joo-Yun Byun, Seokhyun Hong, Teahun Song, JaeHo Lee, Kyuhang Lee, Myoungsil Ko, Cheolkyung Kim, YoungMi Lee, Ho Jeong Lee, YoungHoon Kim, YoungGil Ahn, KweeHyun Suh, Sun-Jin Kim

Cancer Res (2018) 78 (13_Supplement): 4871.

https://doi.org/10.1158/1538-7445.AM2018-4871

Published: 01 July 2018

View article titled, Abstract 4871: Antitumor activity of novel reversible LSD1 inhibitor, HM97211 in preclinical models of SCLC

Journal Articles

Abstract PR05: Control of the melanoma metastatic phenotype by A-to-I microRNA editing

Einav Shoshan, Li Huang, Mayra E. Vasquez, Ho-Jeong Lee, Sun-Jin Kim, Cristina Ivan, George A. Calin, Anil K. Sood, Patrick Hwu, Jeffrey E. Gershenwald, Gal Markel, Isaiah J. Fidler, Menashe Bar-Eli

Cancer Res (2016) 76 (15_Supplement): PR05.

https://doi.org/10.1158/1538-7445.TME16-PR05

Published: 28 July 2016

View article titled, Abstract PR05: Control of the melanoma metastatic phenotype by A-to-I microRNA editing

Journal Articles

Abstract 2943: Hypoxia induced resistance to chemotherapy is regulated by the endothelin receptor axis

Hyun Kyung Yu, Ho Jeong Lee, Fahao Zhang, Qiuyu Wu, Isaiah J. Fidler, Sun Jin Kim

Cancer Res (2016) 76 (14_Supplement): 2943.

https://doi.org/10.1158/1538-7445.AM2016-2943

Published: 15 July 2016

View article titled, Abstract 2943: Hypoxia induced resistance to chemotherapy is regulated by the endothelin receptor axis

Journal Articles

Abstract 737: Transcriptome of glioma growing in the brain is simulated by tumor cells cultured under low oxygen pressure

Ho Jeong Lee, Hyun Kyung Yu, Seung Wook Kim, Sung Il Choi, Junqin He, Isaiah J. Fidler, Sun Jin Kim

Cancer Res (2016) 76 (14_Supplement): 737.

https://doi.org/10.1158/1538-7445.AM2016-737

Published: 15 July 2016

View article titled, Abstract 737: Transcriptome of glioma growing in the brain is simulated by tumor cells cultured under low oxygen pressure

Journal Articles

Abstract 5154: Diagnostic serum markers for metastatic brain tumors identified by cross-species hybridization of microarrays in animal models

Ho Jeong Lee, Sun Jin Kim, Hyun Kyung Yu, Seung Wook Kim, Qiuyu Wu, Junqin He, Isaiah J. Fidler

Cancer Res (2015) 75 (15_Supplement): 5154.

https://doi.org/10.1158/1538-7445.AM2015-5154

Published: 01 August 2015

View article titled, Abstract 5154: Diagnostic serum markers for metastatic brain tumors identified by cross-species hybridization of microarrays in animal models

Journal Articles

Abstract 2056: SIRT1 silencing suppresses prostate cancer growth and metastasis in an orthotopic prostate cancer mouse model

Yan Dai, Lijia Zhu, Elizabeth Cho, Audrey Hagiwara, Douglas Faller, Sun-Jin Kim, Isaiah J. Fidler, Marina Amaro

Cancer Res (2015) 75 (15_Supplement): 2056.

https://doi.org/10.1158/1538-7445.AM2015-2056

Published: 01 August 2015

View article titled, Abstract 2056: SIRT1 silencing suppresses prostate cancer growth and metastasis in an orthotopic prostate cancer mouse model

Journal Articles

Gain of Glucose-Independent Growth upon Metastasis of Breast Cancer Cells to the Brain

Jinyu Chen, Ho-Jeong Lee, Xuefeng Wu, Lei Huo, Sun-Jin Kim, Lei Xu, Yan Wang, Junqing He, Lakshmi R. Bollu, Guang Gao, Fei Su, James Briggs, Xiaojing Liu, Tamar Melman, John M. Asara, Isaiah J. Fidler, Lewis C. Cantley, Jason W. Locasale, Zhang Weihua

Cancer Res (2015) 75 (3): 554–565.

https://doi.org/10.1158/0008-5472.CAN-14-2268

Published: 01 February 2015

View article titled, Gain of Glucose-Independent Growth upon Metastasis of Breast Cancer Cells to the Brain

Includes: Supplementary data

Journal Articles

Abstract 10: Characterization of CD45^-/CD31⁺/CD105⁺ circulating cells in the peripheral blood of patients with gynecological malignancies

Hyun-Kyung Yu, Ho-Jeong Lee, Ha-Na Choi, Jin-Hyung Ahn, Ji-Young Choi, Eun-Jeong Jeong, Hyun-Jeong Seok, Haengseok Song, Ki-Heon Lee, Lee S.H. Yi, Sun Jin Kim, Tae Jin Kim, Jang-Seong Kim

Cancer Res (2014) 74 (19_Supplement): 10.

https://doi.org/10.1158/1538-7445.AM2014-10

Published: 01 October 2014

View article titled, Abstract 10: Characterization of CD45-/CD31+/CD105+ circulating cells in the peripheral blood of patients with gynecological malignancies

Journal Articles

Abstract 3779: Treatment of experimental brain metastasis of human breast cancer by macitentan, a dual antagonist of endothelin receptors combined with paclitaxel

Ho Jeong Lee, Sun Jin Kim, Seung Wook Kim, Junqin He, Qiuyu Wu, Erica J. Lawson, Francois Lehembre, Urs Regenass, Isaiah J. Fidler

Cancer Res (2014) 74 (19_Supplement): 3779.

https://doi.org/10.1158/1538-7445.AM2014-3779

Published: 01 October 2014

View article titled, Abstract 3779: Treatment of experimental brain metastasis of human breast cancer by macitentan, a dual antagonist of endothelin receptors combined with paclitaxel

Journal Articles

Abstract 4878: Modification of gene expression in tumor cells by the culture microenvironment

Seung Wook Kim, Sun Jin Kim, Ho-jeong Lee, Junqin He, Qiuyu Wu, Erica J. Lawson, Isaiah J. Fidler

Cancer Res (2014) 74 (19_Supplement): 4878.

https://doi.org/10.1158/1538-7445.AM2014-4878

Published: 01 October 2014

View article titled, Abstract 4878: Modification of gene expression in tumor cells by the culture microenvironment

Journal Articles

Abstract 5481: Therapy of human LN229 glioblastoma growing in the brain of nude mice by Macitentan, a dual endothelin receptor A and B antagonist, combined with Temozolomide.

Sun Jin Kim, Seung Wook Kim, Hyun Jin Choi, Ho Jeong Lee, Francois Lehembre, Junqin He, Urs Regenass, Charles A Conrad, W.K. Yung, Isaiah J. Fidler

Cancer Res (2013) 73 (8_Supplement): 5481.

https://doi.org/10.1158/1538-7445.AM2013-5481

Published: 15 April 2013

View article titled, Abstract 5481: Therapy of human LN229 glioblastoma growing in the brain of nude mice by Macitentan, a dual endothelin receptor A and B antagonist, combined with Temozolomide.

Journal Articles

Abstract 4951: The role of endothelin axis signaling pathway in astrocyte mediated chemoprotection of tumor cells.

Seung Wook Kim, Sun Jin Kim, Hyun Jin Choi, Ho-Jeong Lee, Junqin He, Qiuyu Wu, Erica J. Lawson, Isaiah J. Fidler

Cancer Res (2013) 73 (8_Supplement): 4951.

https://doi.org/10.1158/1538-7445.AM2013-4951

Published: 15 April 2013

View article titled, Abstract 4951: The role of endothelin axis signaling pathway in astrocyte mediated chemoprotection of tumor cells.

Journal Articles

Abstract 5554: PBI-05204, a supercritical CO₂ extract of Nerium oleander, inhibits the growth of human pancreatic cancer in a Panc-1 orthotopic model by down-regulation of PI3k/mTOR pathways.

Yong Pan, Sun-Jin Kim, Patrea Rhea, Carrie Cartwright, Ho Jeong Lee, Crandell Addington, Mihai Gagea, Robert A. Newman, Peiying Yang

Cancer Res (2013) 73 (8_Supplement): 5554.

https://doi.org/10.1158/1538-7445.AM2013-5554

Published: 15 April 2013

View article titled, Abstract 5554: PBI-05204, a supercritical CO2 extract of Nerium oleander, inhibits the growth of human pancreatic cancer in a Panc-1 orthotopic model by down-regulation of PI3k/mTOR pathways.

Journal Articles

Abstract 4283: Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis

Eun Sung Park, Sun-Jin Kim, Seung Wook Kim, Se-Lyun Yoon, Sun-Hee Leem, Sang-Bae Kim, Soo Mi Kim, Yun-Yong Park, Jae-Ho Cheong, Hyun Goo Woo, Gordon B. Mills, Isaiah J. Fidler, Ju-Seog Lee

Cancer Res (2012) 72 (8_Supplement): 4283.

https://doi.org/10.1158/1538-7445.AM2012-4283

Published: 15 April 2012

View article titled, Abstract 4283: Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis

Journal Articles

Abstract 601: Macitentan (ACT-064992), a tissue-targeting endothelin receptor antagonist enhances therapeutic efficacy of paclitaxel by modulating survival pathways in orthotopic models of metastatic human ovarian cancer

Sun Jin Kim, Jang Seong Kim, Seung Wook Kim, Emily C. Brantley, Seok Joong Yun, Junqin He, Maya K. Marva, Fahao Zhang, Qiuyu Wu, Francois Lehembre, Urs Regenass, Isaiah J. Fidler

Cancer Res (2011) 71 (8_Supplement): 601.

https://doi.org/10.1158/1538-7445.AM2011-601

Published: 15 April 2011

View article titled, Abstract 601: Macitentan (ACT-064992), a tissue-targeting endothelin receptor antagonist enhances therapeutic efficacy of paclitaxel by modulating survival pathways in orthotopic models of metastatic human ovarian cancer

Journal Articles

Abstract 3428: Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy

Sun Jin Kim, Jang-Seong Kim, Eun Sung Park, Ju-Seog Lee, Qintang Lin, Robert R. Langley, Marva Maya, Junqin He, Seung Wook Kim, Zhang Weihua, Krishnakumar Balasubramanian, Dominc Fan, Gordon B. Mills, Mien-Chie Hung, Isaiah J. Fidler

Cancer Res (2010) 70 (8_Supplement): 3428.

https://doi.org/10.1158/1538-7445.AM10-3428

Published: 15 April 2010

View article titled, Abstract 3428: Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy

Journal Articles

Abstract #119: Targeted antivascular therapy of orthotopic human ovarian carcinoma by human apolipoprotein(a) kringle V combined with paclitaxel

Jang-Seong Kim, Ho-Jeong Lee, Seung-Wook Kim, Junqin He, Marva Maya, Yeup Yoon, Sun Jin Kim

Cancer Res (2009) 69 (9_Supplement): 119.

Published: 01 May 2009

View article titled, Abstract #119: Targeted antivascular therapy of orthotopic human ovarian carcinoma by human apolipoprotein(a) kringle V combined with paclitaxel

Journal Articles

Abstract #1133: Isolation and characterization of site-specific osteotropic human prostate cancer cells in nude mouse model

Sun Jin Kim, Jang-Seong Kim, John Papadopoulos, Seung Wook Kim, Junqin He, Marva Maya, Fahao Zhang, Ju-Seog Lee, Dominic Fan, Isaiah Fidler

Cancer Res (2009) 69 (9_Supplement): 1133.

Published: 01 May 2009

View article titled, Abstract #1133: Isolation and characterization of site-specific osteotropic human prostate cancer cells in nude mouse model

NARROW

Abstract 804: Antitumor activity of the potent and novel FLT3 inhibitor HM43239 in acute myeloid leukemia

Abstract 4780: A novel, potent and selective FGFR4 inhibitor, HM81422 in hepatocellular carcinoma with FGFR4-driven pathway activation

Abstract 4871: Antitumor activity of novel reversible LSD1 inhibitor, HM97211 in preclinical models of SCLC

Abstract PR05: Control of the melanoma metastatic phenotype by A-to-I microRNA editing

Abstract 2943: Hypoxia induced resistance to chemotherapy is regulated by the endothelin receptor axis

Abstract 737: Transcriptome of glioma growing in the brain is simulated by tumor cells cultured under low oxygen pressure

Abstract 5154: Diagnostic serum markers for metastatic brain tumors identified by cross-species hybridization of microarrays in animal models

Abstract 2056: SIRT1 silencing suppresses prostate cancer growth and metastasis in an orthotopic prostate cancer mouse model

Gain of Glucose-Independent Growth upon Metastasis of Breast Cancer Cells to the Brain

Abstract 10: Characterization of CD45^-/CD31⁺/CD105⁺ circulating cells in the peripheral blood of patients with gynecological malignancies

Abstract 3779: Treatment of experimental brain metastasis of human breast cancer by macitentan, a dual antagonist of endothelin receptors combined with paclitaxel

Abstract 4878: Modification of gene expression in tumor cells by the culture microenvironment

Abstract 5481: Therapy of human LN229 glioblastoma growing in the brain of nude mice by Macitentan, a dual endothelin receptor A and B antagonist, combined with Temozolomide.

Abstract 4951: The role of endothelin axis signaling pathway in astrocyte mediated chemoprotection of tumor cells.

Abstract 5554: PBI-05204, a supercritical CO₂ extract of Nerium oleander, inhibits the growth of human pancreatic cancer in a Panc-1 orthotopic model by down-regulation of PI3k/mTOR pathways.

Abstract 4283: Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis

Abstract 601: Macitentan (ACT-064992), a tissue-targeting endothelin receptor antagonist enhances therapeutic efficacy of paclitaxel by modulating survival pathways in orthotopic models of metastatic human ovarian cancer

Abstract 3428: Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy

Abstract #119: Targeted antivascular therapy of orthotopic human ovarian carcinoma by human apolipoprotein(a) kringle V combined with paclitaxel

Abstract #1133: Isolation and characterization of site-specific osteotropic human prostate cancer cells in nude mouse model

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