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Journal Articles

Abstract 6355: A characterisation of direct and indirect transcription factor inhibition to target brachyury in chordoma

Hadley E. Sheppard, Alessandra Dall’Agnese, Woojun D. Park, M. Shamim Shamim, Julien Dubrulle, Hannah L. Johnson, Fabio Stossi, Josh Sommer, Joan Levy, Tanaz Sharifnia, Mathias Wawer, Behnam Nabet, Paul A. Clemons, Stuart L. Schreiber, Paul Clarke, Rick Young, Charles Y. Lin, Paul Workman

Cancer Res (2022) 82 (12_Supplement): 6355.

DOI: https://doi.org/10.1158/1538-7445.AM2022-6355

Published: 15 June 2022

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Journal Articles

Abstract LB216: Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity

Hadley E. Sheppard, Alessandra Dall'Agnese, Woojun D. Park, Hamza Shamim, Julien Dubrulle, Hannah L. Johnson, Fabio Stossi, Patricia Cogswell, Josh Sommer, Joan Levy, Tanaz Sharifnia, Mathias J. Wawer, Paul A. Clemons, Behnam Nabet, Nathanael S. Gray, Stuart L. Schreiber, Paul Workman, Richard A. Young, Charles Y. Lin

Cancer Res (2021) 81 (13_Supplement): LB216.

DOI: https://doi.org/10.1158/1538-7445.AM2021-LB216

Published: 01 July 2021

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Journal Articles

Abstract PR04: Transcriptional regulation of mitochondrial metabolism by TIF1γ drives erythroid progenitor differentiation

Cancer Res (2020) 80 (23_Supplement): PR04.

DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PR04

Published: 02 December 2020

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Journal Articles

Abstract NG13: Metabolomic adaptations and correlates of survival to immune checkpoint blockade

Cancer Res (2020) 80 (16_Supplement): NG13.

DOI: https://doi.org/10.1158/1538-7445.AM2020-NG13

Published: 15 August 2020

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Journal Articles

Abstract SY42-01: Chemical biology-based approach to understanding and overcoming resistance of cancers to therapies

Stuart L. Schreiber

Cancer Res (2019) 79 (13_Supplement): SY42-01.

DOI: https://doi.org/10.1158/1538-7445.AM2019-SY42-01

Published: 01 July 2019

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Journal Articles

Abstract 1006: Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

Matthew J. Hangauer, Vasanthi S. Viswanathan, Matthew J. Ryan, Dhruv Bole, Jake Eaton, Stuart L. Schreiber, Frank McCormick, McManus T. Michael

Cancer Res (2017) 77 (13_Supplement): 1006.

DOI: https://doi.org/10.1158/1538-7445.AM2017-1006

Published: 01 July 2017

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Journal Articles

Abstract 4974: Pharmacogenomic interactions in glioblastoma cell line models

Cancer Res (2017) 77 (13_Supplement): 4974.

DOI: https://doi.org/10.1158/1538-7445.AM2017-4974

Published: 01 July 2017

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Journal Articles

Abstract B38: Developing a functional genomics platform to interrogate rare pediatric cancers

Cancer Res (2016) 76 (5_Supplement): B38.

DOI: https://doi.org/10.1158/1538-7445.PEDCA15-B38

Published: 04 April 2016

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Journal Articles

KRAS Genomic Status Predicts the Sensitivity of Ovarian Cancer Cells to Decitabine

Michelle L. Stewart, Pablo Tamayo, Andrew J. Wilson, Stephanie Wang, Yun Min Chang, Jong W. Kim, Dineo Khabele, Alykhan F. Shamji, Stuart L. Schreiber

Cancer Res (2015) 75 (14): 2897–2906.

DOI: https://doi.org/10.1158/0008-5472.CAN-14-2860

Published: 14 July 2015

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Includes: Supplementary data

Journal Articles

Abstract IA1: Cancer dependencies defined by genomic alterations and targeted by small molecules

Stuart L. Schreiber

Cancer Res (2012) 72 (13_Supplement): IA1.

DOI: https://doi.org/10.1158/1538-7445.CSB12-IA1

Published: 06 November 2014

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Journal Articles

Abstract 181: Therapeutic approaches to metastasis induced by mesenchymal stem cells in the tumor microenvironment

Shrikanta Chattopadhyay, Cherrie Huang, Siddhartha Mukherjee, Rushdia Z. Yusuf, Vasanthi Viswanathan, Ben S. Wittner, Jeff Gentry, Alykhan Shamji, Sridhar Ramaswamy, David T. Scadden, Stuart L. Schreiber

Cancer Res (2014) 74 (19_Supplement): 181.

DOI: https://doi.org/10.1158/1538-7445.AM2014-181

Published: 01 October 2014

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Journal Articles

Abstract 4596: An integrated genomic characterization of the target of a small molecule identifies a novel cancer dependency

Luc M. de Waal, Tim A. Lewis, Lara Gechijian, Aviad Tsherniak, Willmen Youngsaye, Matthew Rees, Oliver Mikse, Mark Hickey, Patrick Faloon, Nicola Tolliday, Angela Koehler, Monica Schenone, Kwok Wong, Alykhan Shamji, Benito Munoz, Stuart L. Schreiber, Heidi Greulich, Matthew L. Meyerson

Cancer Res (2014) 74 (19_Supplement): 4596.

DOI: https://doi.org/10.1158/1538-7445.AM2014-4596

Published: 01 October 2014

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Journal Articles

Abstract IA25: Linking genetic features of human cancers and histone-modifying enzymes for future cancer therapies

Stuart L. Schreiber

Cancer Res (2013) 73 (13_Supplement): IA25.

DOI: https://doi.org/10.1158/1538-7445.CEC13-IA25

Published: 13 May 2014

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Journal Articles

Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer

Mohamed E. Abazeed, Drew J. Adams, Kristen E. Hurov, Pablo Tamayo, Chad J. Creighton, Dmitriy Sonkin, Andrew O. Giacomelli, Charles Du, Daniel F. Fries, Kwok-Kin Wong, Jill P. Mesirov, Jay S. Loeffler, Stuart L. Schreiber, Peter S. Hammerman, Matthew Meyerson

Cancer Res (2013) 73 (20): 6289–6298.

DOI: https://doi.org/10.1158/0008-5472.CAN-13-1616

Published: 14 October 2013

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Includes: Supplementary data

Journal Articles

Abstract 2313: DDR1 receptor kinase pathway as an emerging target in cancer therapeutics

Hyung-Gu Kim, Anna Mandinova, So Young Hwang, Stuart L. Schreiber, Sam W. Lee

Cancer Res (2011) 71 (8_Supplement): 2313.

DOI: https://doi.org/10.1158/1538-7445.AM2011-2313

Published: 15 April 2011

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Journal Articles

Abstract 2985: DNA-damage related histone marks can distinguish the anti-tumor effects of established and novel histone deacetylase inhibitors in ovarian cancer cells

Andrew J. Wilson, Ed Holson, Srividya Bhaskara, Jahred Carlise, Stuart L. Schreiber, Scott W. Hiebert, Dineo Khabele

Cancer Res (2010) 70 (8_Supplement): 2985.

DOI: https://doi.org/10.1158/1538-7445.AM10-2985

Published: 15 April 2010

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Journal Articles

Small Molecules, Big Players: the National Cancer Institute's Initiative for Chemical Genetics

Nicola Tolliday, Paul A. Clemons, Paul Ferraiolo, Angela N. Koehler, Timothy A. Lewis, Xiaohua Li, Stuart L. Schreiber, Daniela S. Gerhard, Scott Eliasof

Cancer Res (2006) 66 (18): 8935–8942.

DOI: https://doi.org/10.1158/0008-5472.CAN-06-2552

Published: 18 September 2006

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Journal Articles

Network-like properties of chromatin: Implications for basic science and opportunities for clinical application.

Bradley E. Bernstein, Stuart L. Schreiber

Cancer Res (2004) 64 (7_Supplement): 1306.

Published: 01 April 2004

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NARROW

Abstract 6355: A characterisation of direct and indirect transcription factor inhibition to target brachyury in chordoma

Abstract LB216: Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity

Abstract PR04: Transcriptional regulation of mitochondrial metabolism by TIF1γ drives erythroid progenitor differentiation

Abstract NG13: Metabolomic adaptations and correlates of survival to immune checkpoint blockade

Abstract SY42-01: Chemical biology-based approach to understanding and overcoming resistance of cancers to therapies

Abstract 1006: Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

Abstract 4974: Pharmacogenomic interactions in glioblastoma cell line models

Abstract B38: Developing a functional genomics platform to interrogate rare pediatric cancers

KRAS Genomic Status Predicts the Sensitivity of Ovarian Cancer Cells to Decitabine

Abstract IA1: Cancer dependencies defined by genomic alterations and targeted by small molecules

Abstract 181: Therapeutic approaches to metastasis induced by mesenchymal stem cells in the tumor microenvironment

Abstract 4596: An integrated genomic characterization of the target of a small molecule identifies a novel cancer dependency

Abstract IA25: Linking genetic features of human cancers and histone-modifying enzymes for future cancer therapies

Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer

Abstract 2313: DDR1 receptor kinase pathway as an emerging target in cancer therapeutics

Abstract 2985: DNA-damage related histone marks can distinguish the anti-tumor effects of established and novel histone deacetylase inhibitors in ovarian cancer cells

Small Molecules, Big Players: the National Cancer Institute's Initiative for Chemical Genetics

Network-like properties of chromatin: Implications for basic science and opportunities for clinical application.

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