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Abstract CT233: Serum thymidine kinase 1 levels as a predictive marker for castration resistance in metastatic prostate cancer

Aino Siltari, Paavo Raittinen, Jarno Riikonen, Juha Koskimäki, Tomi Pakarainen, Mikael Anttinen, Otto Ettala, Teuvo Tammela, Stig Linder, Teemu J. Murtola

Cancer Res (2024) 84 (7_Supplement): CT233.

https://doi.org/10.1158/1538-7445.AM2024-CT233

Published: 05 April 2024

View article titled, Abstract CT233: Serum thymidine kinase 1 levels as a predictive marker for castration resistance in metastatic prostate cancer

Journal Articles

Abstract 571: CRISPR/Cas9 screening identifies the proteasome subunit PSMC6 as key for the survival of cisplatin-resistant ovarian carcinoma cells

Matteo Costantino, Padraig D'arcy, Luca Mirra, Cristina Corno, Giovanni L. Beretta, Johannes Gubat, Pietro Pratesi, Chiara M. Ciniselli, Paolo Verderio, Stig Linder, Paola Perego

Cancer Res (2024) 84 (6_Supplement): 571.

https://doi.org/10.1158/1538-7445.AM2024-571

Published: 22 March 2024

View article titled, Abstract 571: CRISPR/Cas9 screening identifies the proteasome subunit PSMC6 as key for the survival of cisplatin-resistant ovarian carcinoma cells

Journal Articles

Abstract 3000: Zebrafish tumor-derived xenograft-models for improved diagnosis and treatment planning in ovarian cancer patients

Karthik Selvaraj, Malin Vildevall, Lina Wirestam, Zaheer Ali, Anna Erkstam, Annelie Abrahamsson, Åsa Rydmark Kersley, Preben Kjölhede, Stig Linder, Charlotta Dabrosin, Anna Fahlgren, Lasse Jensen

Cancer Res (2021) 81 (13_Supplement): 3000.

https://doi.org/10.1158/1538-7445.AM2021-3000

Published: 01 July 2021

View article titled, Abstract 3000: Zebrafish tumor-derived xenograft-models for improved diagnosis and treatment planning in ovarian cancer patients

Journal Articles

Abstract 1859: Inhibition of proteasome deubiquitinase activity prevents cytoprotective aggresome formation in cancer cells

Ellin-Kristina Hillert, Slavica Brjnic, Magdalena Mazurkiewicz, Rolf Larsson, Mårten Fryknäs, Lisa Swanton, Stephen High, Stig Linder, Padraig B. D'Arcy

Cancer Res (2018) 78 (13_Supplement): 1859.

https://doi.org/10.1158/1538-7445.AM2018-1859

Published: 01 July 2018

View article titled, Abstract 1859: Inhibition of proteasome deubiquitinase activity prevents cytoprotective aggresome formation in cancer cells

Journal Articles

Abstract 2795: Screening and characterization of drugs that inhibit the ubiquitin-proteasome system

Karthik Selvaraju, Arjan Mofers, Paola Pellegrini, Ellin-Kristina Hillert, Padraig D'Arcy, Stig Linder

Cancer Res (2018) 78 (13_Supplement): 2795.

https://doi.org/10.1158/1538-7445.AM2018-2795

Published: 01 July 2018

View article titled, Abstract 2795: Screening and characterization of drugs that inhibit the ubiquitin-proteasome system

Journal Articles

Proteasome Addiction Defined in Ewing Sarcoma Is Effectively Targeted by a Novel Class of 19S Proteasome Inhibitors

Cancer Res (2016) 76 (15): 4525–4534.

https://doi.org/10.1158/0008-5472.CAN-16-1040

Published: 31 July 2016

View article titled, Proteasome Addiction Defined in Ewing Sarcoma Is Effectively Targeted by a Novel Class of 19S Proteasome Inhibitors

Includes: Supplementary data

Journal Articles

Abstract 1736: The anticancer activity of the DUB inhibitor b-AP15 is associated with accumulation of proteasome bound ubiquitin and oxidative stress

Magdalena Mazurkiewicz, Slavica Brnjic, Mårten Fryknäs, Chao Sun, Xiaonan Zhang, Rolf Larsson, Pádraig D'Arcy, Stig Linder

Cancer Res (2015) 75 (15_Supplement): 1736.

https://doi.org/10.1158/1538-7445.AM2015-1736

Published: 01 August 2015

View article titled, Abstract 1736: The anticancer activity of the DUB inhibitor b-AP15 is associated with accumulation of proteasome bound ubiquitin and oxidative stress

Journal Articles

Abstract 323: Spheroid-based high throughput screening for identification of molecules targeting different tumor microenvironment characteristics

Wojciech Senkowski, Xiaonan Zhang, Peter Nygren, Maria Hägg Olofsson, Mats Gustafsson, Stig Linder, Rolf Larsson, Mårten Fryknäs

Cancer Res (2015) 75 (15_Supplement): 323.

https://doi.org/10.1158/1538-7445.AM2015-323

Published: 01 August 2015

View article titled, Abstract 323: Spheroid-based high throughput screening for identification of molecules targeting different tumor microenvironment characteristics

Journal Articles

Abstract 4557A: Development of the proteasome deubiquitinase inhibitor VLX1570 for treatment of multiple myeloma

Xin Wang, Chitralehka Mohanty, Padraig D'Arcy, Maria Hägg Olofsson, Felicitas Bossler, Asher Chanan-Khan, Stig Linder

Cancer Res (2015) 75 (15_Supplement): 4557A.

https://doi.org/10.1158/1538-7445.AM2015-4557A

Published: 01 August 2015

View article titled, Abstract 4557A: Development of the proteasome deubiquitinase inhibitor VLX1570 for treatment of multiple myeloma

Journal Articles

Abstract 3781: A spheroid-based screen identifies mitochondrial targeting as a promising strategy for cancer treatment and drug repositioning

Wojciech Senkowski, Xiaonan Zhang, Maria Hägg Olofsson, Stig Linder, Rolf Larsson, Mårten Fryknäs

Cancer Res (2014) 74 (19_Supplement): 3781.

https://doi.org/10.1158/1538-7445.AM2014-3781

Published: 01 October 2014

View article titled, Abstract 3781: A spheroid-based screen identifies mitochondrial targeting as a promising strategy for cancer treatment and drug repositioning

Journal Articles

Abstract 3999: Spontaneous time-dependent accumulation of interferon-regulatory factor 9 induces chemo-resistance in colon carcinoma cells independently of STAT1 signaling.

Iryna Kolosenko, Mårten Fryknäs, Hanif Rassoolzadeh, Paola Pellegrini, Slavica Brnjic, Per Johnsson, Giuseppe Di Lernia, Dan Grander, Rolf Larsson, Katja Pokrovskaja, Stig Linder, Angelo De Milito De Milito

Cancer Res (2013) 73 (8_Supplement): 3999.

https://doi.org/10.1158/1538-7445.AM2013-3999

Published: 15 April 2013

View article titled, Abstract 3999: Spontaneous time-dependent accumulation of interferon-regulatory factor 9 induces chemo-resistance in colon carcinoma cells independently of STAT1 signaling.

Journal Articles

Abstract #1951: Identification of drugs for treatment of solid tumors by spheroid screening

Slavica Brnjic, Walid Fayad, Maria Berndtsson, Maria Hägg Olofsson, Mårten Fryknäs, Rolf Larsson, Stig Linder

Cancer Res (2009) 69 (9_Supplement): 1951.

Published: 01 May 2009

View article titled, Abstract #1951: Identification of drugs for treatment of solid tumors by spheroid screening

Journal Articles

Abstract #3282: Identification and characterization of NSC687852: A novel isopeptidase inhibitor that induces rapid apoptosis in vitro and in vivo

Padraig D'Arcy, Slavica Brnjic, Maria Berndtsson, Maria Hägg, Stig Linder

Cancer Res (2009) 69 (9_Supplement): 3282.

Published: 01 May 2009

View article titled, Abstract #3282: Identification and characterization of NSC687852: A novel isopeptidase inhibitor that induces rapid apoptosis in vitro and in vivo

Journal Articles

Picropodophyllotoxin or Podophyllotoxin Does Not Induce Cell Death via Insulin-like Growth Factor-I Receptor

Stig Linder, Maria C. Shoshan, Radhey S. Gupta

Cancer Res (2007) 67 (6): 2899.

https://doi.org/10.1158/0008-5472.CAN-06-0635

Published: 15 March 2007

View article titled, Picropodophyllotoxin or Podophyllotoxin Does Not Induce Cell Death via Insulin-like Growth Factor-I Receptor

Journal Articles

Differential modes of action of cisplatin and oxaliplatin: Involvement of NO and reactive oxygen in induction of apoptosis

Maria Shoshan, Maria Berndtsson, Claudia Burz, Emma Hernlund, Özgur Kutuk, Elin Jerremalm, Aris Panaretakis, Stig Linder

Cancer Res (2005) 65 (9_Supplement): 1260.

Published: 01 May 2005

View article titled, Differential modes of action of cisplatin and oxaliplatin: Involvement of NO and reactive oxygen in induction of apoptosis

Journal Articles

Differentiation between Cell Death Modes Using Measurements of Different Soluble Forms of Extracellular Cytokeratin 18

Gero Kramer, Hamdiye Erdal, Helena J. M. M. Mertens, Marius Nap, Julian Mauermann, Georg Steiner, Michael Marberger, Kenneth Bivén, Maria C. Shoshan, Stig Linder

Cancer Res (2004) 64 (5): 1751–1756.

https://doi.org/10.1158/0008-5472.CAN-03-2455

Published: 02 March 2004

View article titled, Differentiation between Cell Death Modes Using Measurements of Different Soluble Forms of Extracellular Cytokeratin 18

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Abstract CT233: Serum thymidine kinase 1 levels as a predictive marker for castration resistance in metastatic prostate cancer

Abstract 571: CRISPR/Cas9 screening identifies the proteasome subunit PSMC6 as key for the survival of cisplatin-resistant ovarian carcinoma cells

Abstract 3000: Zebrafish tumor-derived xenograft-models for improved diagnosis and treatment planning in ovarian cancer patients

Abstract 1859: Inhibition of proteasome deubiquitinase activity prevents cytoprotective aggresome formation in cancer cells

Abstract 2795: Screening and characterization of drugs that inhibit the ubiquitin-proteasome system

Proteasome Addiction Defined in Ewing Sarcoma Is Effectively Targeted by a Novel Class of 19S Proteasome Inhibitors

Abstract 1736: The anticancer activity of the DUB inhibitor b-AP15 is associated with accumulation of proteasome bound ubiquitin and oxidative stress

Abstract 323: Spheroid-based high throughput screening for identification of molecules targeting different tumor microenvironment characteristics

Abstract 4557A: Development of the proteasome deubiquitinase inhibitor VLX1570 for treatment of multiple myeloma

Abstract 3781: A spheroid-based screen identifies mitochondrial targeting as a promising strategy for cancer treatment and drug repositioning

Abstract 3999: Spontaneous time-dependent accumulation of interferon-regulatory factor 9 induces chemo-resistance in colon carcinoma cells independently of STAT1 signaling.

Abstract #1951: Identification of drugs for treatment of solid tumors by spheroid screening

Abstract #3282: Identification and characterization of NSC687852: A novel isopeptidase inhibitor that induces rapid apoptosis in vitro and in vivo

Picropodophyllotoxin or Podophyllotoxin Does Not Induce Cell Death via Insulin-like Growth Factor-I Receptor

Differential modes of action of cisplatin and oxaliplatin: Involvement of NO and reactive oxygen in induction of apoptosis

Differentiation between Cell Death Modes Using Measurements of Different Soluble Forms of Extracellular Cytokeratin 18

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