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Steven M. Kornblau
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Journal Articles

Abstract 1646: IL-23R is a regulator of the mitotic spindle and is critical for cell viability in AML

Nathan Duong, Dilshad H. Khan, Geethu E. Thomas, Rose Hurren, Jong Bok Lee, Jonathan St-Germain, Lily Drimmer, Yongran Yan, Neil Maclean, Marcela Gronda, Vincent Rondeau, Brandon D. Brown, Courtney L. Jones, Hong Chang, Andrea Arruda, Mark D. Minden, Li Zhang, Steven M. Kornblau, Brian Raught, Vito Spadavecchio, Aaron D. Schimmer
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1646.
https://doi.org/10.1158/1538-7445.AM2024-1646
Published: 22 March 2024
View article titled, Abstract 1646: IL-23R is a regulator of the mitotic spindle and is critical for cell viability in AML
Journal Articles

Abstract 3400: Single-cell proteogenomics analysis of AML samples treated with decitabine and venetoclax reveals divergent treatment escape mechanisms

Yi June Kim, Zongrui Li, Abhishek Maiti, Tomoyuki Tanaka, Hidetaka Uryu, Ken Furudate, Kala Hayes, Naval Daver, Naveen Pemmaraju, Tapan M. Kadia, Farhad Ravandi, Nicholas J. Short, Maro Ohanian, Gautam Borthakur, Nitin Jain, Ghayas C. Issa, Lucia Masarova, Steven M. Kornblau, William G. Wierda, Sanam Loghavi, Sa A. Wang, Guillermo Garcia-Manero, Hagop Kantarjian, Courtney D. DiNardo, Marina Y. Konopleva, Koichi Takahashi
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3400.
https://doi.org/10.1158/1538-7445.AM2024-3400
Published: 22 March 2024
View article titled, Abstract 3400: Single-cell proteogenomics analysis of AML samples treated with decitabine and venetoclax reveals divergent treatment escape mechanisms
Journal Articles

Abstract 333: Interleukin 23 receptor is a critical regulator of the mitotic spindle and necessary for AML viability

Nathan Duong, Dilshad H. Khan, Geethu E. Thomas, Rose Hurren, Jong Bok Lee, Jonathan St-Germain, Lily Drimmer, Yongran Yan, Neil MacLean, Marcela Gronda, Brandon D. Brown, Brian Raught, Andrea Arruda, Hong Chang, Mark D. Minden, Li Zhang, Steven M. Kornblau, Vito Spadavecchio, Aaron D. Schimmer
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 333.
https://doi.org/10.1158/1538-7445.AM2023-333
Published: 04 April 2023
View article titled, Abstract 333: Interleukin 23 receptor is a critical regulator of the mitotic spindle and necessary for AML viability
Journal Articles

VEGFC Antibody Therapy Drives Differentiation of AML

Kim R. Kampen, Frank J.G. Scherpen, Hasan Mahmud, Arja ter Elst, André B. Mulder, Victor Guryev, Han J.M.P. Verhagen, Kim De Keersmaecker, Linda Smit, Steven M. Kornblau, Eveline S.J.M. De Bont
Journal: Cancer Research
Cancer Res (2018) 78 (20): 5940–5948.
https://doi.org/10.1158/0008-5472.CAN-18-0250
Published: 15 October 2018
View article titled, VEGFC Antibody Therapy Drives Differentiation of AML
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Includes: Supplementary data
Journal Articles

Abstract 3884: Novel RUNX1 targeted therapy for AML expressing mutant RUNX1

Christopher P. Mill, Courtney D. DiNardo, Warren Fiskus, Dyana T. Saenz, Agnieszka J. Nowak, Baohua Sun, David N. Saenz, Steven M. Kornblau, Kapil N. Bhalla
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3884.
https://doi.org/10.1158/1538-7445.AM2018-3884
Published: 01 July 2018
View article titled, Abstract 3884: Novel RUNX1 targeted therapy for AML expressing mutant RUNX1
Journal Articles

Abstract 2699: Proteomic landscape of de novo pediatric acute myeloid leukemia

Fieke W. Hoff, Yihua Qiu, Wendy Hu, Amina A. Qutub, Alan S. Gamis, Richard Aplenc, E Anders Kolb, Todd A. Alonzo, Eveline SJM de Bont, Terzah M. Horton, Steven M. Kornblau
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2699.
https://doi.org/10.1158/1538-7445.AM2018-2699
Published: 01 July 2018
View article titled, Abstract 2699: Proteomic landscape of de novo pediatric acute myeloid leukemia
Journal Articles

Abstract 451: Proteomic profiling of the unfolded protein response identifies patients benefiting from bortezomib in pediatric acute myeloid leukemia

Fieke W. Hoff, Yihua Qiu, Wendy Hu, Amina A. Qutub, Alon S. Gamis, Richard Aplenc, E Anders Kolb, Todd A. Alonzo, Eveline SJM de Bont, Steven M. Kornblau, Terzah Horton
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 451.
https://doi.org/10.1158/1538-7445.AM2018-451
Published: 01 July 2018
View article titled, Abstract 451: Proteomic profiling of the unfolded protein response identifies patients benefiting from bortezomib in pediatric acute myeloid leukemia
Journal Articles

Abstract 802: Targeted inhibition of KDM1A and BET proteins or DNMT1 exerts synergistic lethal activity against human AML blast progenitor cells

Warren C. Fiskus, Christopher P. Mill, Dyana T. Saenz, Agnieszka J. Nowak, Baohua Sun, David N. Saenz, Steven M. Kornblau, Sunil Sharma, Kapil N. Bhalla
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 802.
https://doi.org/10.1158/1538-7445.AM2018-802
Published: 01 July 2018
View article titled, Abstract 802: Targeted inhibition of KDM1A and BET proteins or DNMT1 exerts synergistic lethal activity against human AML blast progenitor cells
Journal Articles

Abstract 2450: Mutational profiling of MLL-PTD acute myeloid leukemia

Lingwen Ding, Qiaoyang Sun, Kar-Tong Tan, Wenwen Chien, Anand Mayakonda, Dechen Lin, Xinyi Loh, Jinfen Xiao, Manja Meggendorfer, Tamara Alpermann, Manoj Garg, Su-Lin Lim, Vikas Madan, Norimichi Hattori, Yasunobu Nagata, Satoru Miyano, Allen Yeoh Eng Juh, Hsin-An Hou, Yan-Yi Jiang, Yan-Yi Jiang, Sumiko Takao, Li-Zhen Liu, Siew-Zhuan Tan, Siew-Zhuan Tan, Michael Lill, Mutsumi Hayashi, Akitoshi Kinoshita, Hagop M. Kantarjian, Steven M. Kornblau, Seishi Ogawa, Torsten Haferlach, Henry Yang, H. Phillip Koeffler
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2450.
https://doi.org/10.1158/1538-7445.AM2017-2450
Published: 01 July 2017
View article titled, Abstract 2450: Mutational profiling of MLL-PTD acute myeloid leukemia
Journal Articles

Mutational Landscape of Pediatric Acute Lymphoblastic Leukemia

Ling-Wen Ding, Qiao-Yang Sun, Kar-Tong Tan, Wenwen Chien, Anand Mayakonda Thippeswamy, Allen Eng Juh Yeoh, Norihiko Kawamata, Yasunobu Nagata, Jin-Fen Xiao, Xin-Yi Loh, De-Chen Lin, Manoj Garg, Yan-Yi Jiang, Liang Xu, Su-Lin Lim, Li-Zhen Liu, Vikas Madan, Masashi Sanada, Lucia Torres Fernández, Hema Preethi, Michael Lill, Hagop M. Kantarjian, Steven M. Kornblau, Satoru Miyano, Der-Cherng Liang, Seishi Ogawa, Lee-Yung Shih, Henry Yang, H. Phillip Koeffler
Journal: Cancer Research
Cancer Res (2017) 77 (2): 390–400.
https://doi.org/10.1158/0008-5472.CAN-16-1303
Published: 16 January 2017
View article titled, Mutational Landscape of Pediatric Acute Lymphoblastic Leukemia
Open the PDF for Mutational Landscape of Pediatric Acute Lymphoblastic Leukemia in another window
Includes: Supplementary data
Journal Articles

Abstract 2779: A CpG island methylator phenotype in acute myeloid leukemia independent of IDH mutations and associated with a favorable outcome

Andrew D. Kelly, Heike Kroeger, Jumpei Yamazaki, Rodolphe Taby, Frank Neumann, Sijia Yu, Justin T. Lee, Rong He, Shoudan Liang, Yue Lu, Matteo Cesaroni, Sherry A. Pierce, Steven M. Kornblau, Carlos E. Bueso-Ramos, Farhad Ravandi, Hagop M. Kantarjain, Jaroslav Jelinek, Jean-Pierre J. Issa
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2779.
https://doi.org/10.1158/1538-7445.AM2016-2779
Published: 15 July 2016
View article titled, Abstract 2779: A CpG island methylator phenotype in acute myeloid leukemia independent of IDH mutations and associated with a favorable outcome
Journal Articles

Abstract 5302: Genome-wide methylation analysis reveals multiple epigenetic subtypes of acute myeloid leukemia

Andrew D. Kelly, Heike Kroeger, Jumpei Yamazaki, Rodolphe Taby, Frank Neumann, Justin T. Lee, Rong He, Shoudan Liang, Yue Lu, Matteo Cesaroni, Sherry A. Pierce, Steven M. Kornblau, Carlos E. Bueso-Ramos, Farhad Ravandi, Hagop M. Kantarjian, Jaroslav Jelinek, Jean-Pierre J. Issa
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5302.
https://doi.org/10.1158/1538-7445.AM2015-5302
Published: 01 August 2015
View article titled, Abstract 5302: Genome-wide methylation analysis reveals multiple epigenetic subtypes of acute myeloid leukemia
Journal Articles

Abstract 4369: Rearrangements of the erythropoietin receptor are recurrent in Ph-like acute lymphoblastic leukemia and are sensitive to Jak2 inhibition

Ilaria Iacobucci, Kathryn G. Roberts, Yongjin Li, Jinghui Zhang, Richard C. Harvey, Debbie Payne-Turner, Marcus Valentine, Kelly McCastlain, John Easton, I-Ming Chen, Michael Rusch, Steven M. Kornblau, Marina Konopleva, Elisabeth Paietta, Jacob M. Rowe, Ching-Hon Pui, Julie M. Gastier-Foster, Shalini Reshmi, Mignon L. Loh, Cheryl Willman, James R. Downing, Stephen P. Hunger, Charles G. Mullighan
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4369.
https://doi.org/10.1158/1538-7445.AM2015-4369
Published: 01 August 2015
View article titled, Abstract 4369: Rearrangements of the erythropoietin receptor are recurrent in Ph-like acute lymphoblastic leukemia and are sensitive to Jak2 inhibition
Journal Articles

Abstract 5310: Integrated functional proteomic profiling in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML): MDS-like signature is associated with favorable outcome in patients with AML

Young Kwang Chae, Suk Young Yoo, Kevin R. Coombes, Steven M. Kornblau
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5310.
https://doi.org/10.1158/1538-7445.AM2014-5310
Published: 01 October 2014
View article titled, Abstract 5310: Integrated functional proteomic profiling in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML): MDS-like signature is associated with favorable outcome in patients with AML
Journal Articles

Abstract 3083: The genetic landscape of Ph-like acute lymphoblastic leukemia

Kathryn G. Roberts, Yongjin Li, Debbie Payne-Turner, Jinghui Zhang, Richard C. Harvey, Yung-Li Yang, Guangchun Song, Jing Ma, Shann-Ching Chen, Jinjun Cheng, Natalia Santiago-Morales, Ilaria Iacobucci, Meenakshi Devidas, I-Ming Chen, Shalini Reshmi, Michael Rusch, Pankaj Gupta, Naomi J. Winick, William L. Carroll, Nyla A. Heerema, Andrew J. Carroll, Elizabeth A. Raetz, Guido Marcucci, Clara D. Bloomfield, Wendy Stock, Steven M. Kornblau, Elisabeth Paietta, Ching-Hon Pui, Sima Jeha, James Downing, Daniela S. Gerhard, Julie M. Gastier-Foster, Mignon L. Loh, Cheryl Willman, Stephen P. Hunger, Charles G. Mullighan
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3083.
https://doi.org/10.1158/1538-7445.AM2014-3083
Published: 01 October 2014
View article titled, Abstract 3083: The genetic landscape of Ph-like acute lymphoblastic leukemia
Journal Articles

Abstract 2302: CpG hypermethylation marks potentially curable acute myeloid leukemia

Jaroslav Jelinek, Heike Kroeger, Jumpei Yamazaki, Rodolphe Taby, Frank Neumann, Justin T. Lee, Rong He, Shoudan Liang, Yue Lu, Matteo Cesaroni, Sherry A. Pierce, Steven M. Kornblau, Carlos E. Bueso-Ramos, Farhad Ravandi-Kashani, Hagop M. Kantarjian, Jean-Pierre J. Issa
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2302.
https://doi.org/10.1158/1538-7445.AM2014-2302
Published: 01 October 2014
View article titled, Abstract 2302: CpG hypermethylation marks potentially curable acute myeloid leukemia
Journal Articles

Abstract 4120: Low expression of PP2A/B55α is associated with increased MiR-191 expression and relapse in acute myeloid leukemia.

Peter P. Ruvolo, Vivian Ruvolo, Rodrigo Jacamo, Yihua Qiu, Kevin Coombes, Nianxiang Zhang, Ramiro Garzon, Steven M. Kornblau, Carlo Croce, Michael Andreeff
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4120.
https://doi.org/10.1158/1538-7445.AM2013-4120
Published: 15 April 2013
View article titled, Abstract 4120: Low expression of PP2A/B55α is associated with increased MiR-191 expression and relapse in acute myeloid leukemia.
Journal Articles

Abstract LB-293: Phase II study of the oral AKT inhibitor, MK-2206, for acute myeloid leukemia (AML) in second relapse.

Marina Y. Konopleva, Roland B. Walter, Stefan Faderl, Elias Jabbour, Zhihong Zeng, Gautam Borthakur, Peter Ruvolo, Xuelin Huang, Tapan Kadia, Jennie Feliu, Jan A. Burger, Michael Andreeff, Wenbin Liu, Steven M. Kornblau, Keith Baggerly, Elihu Estey, Hagop Kantarjian
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-293.
https://doi.org/10.1158/1538-7445.AM2013-LB-293
Published: 15 April 2013
View article titled, Abstract LB-293: Phase II study of the oral AKT inhibitor, MK-2206, for acute myeloid leukemia (AML) in second relapse.
Journal Articles

Abstract 3659: The AKT inhibitor MK-2206 promotes apoptosis in acute myeloid leukemia cells

Peter P. Ruvolo, Zhihong Zeng, Vivian R. Ruvolo, Gautam Borthakur, Steven M. Kornblau, Michael Andreeff, Marina Konopleva
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3659.
https://doi.org/10.1158/1538-7445.AM2012-3659
Published: 15 April 2012
View article titled, Abstract 3659: The AKT inhibitor MK-2206 promotes apoptosis in acute myeloid leukemia cells
Journal Articles

SOX4 gene expression in human leukemic and benign hematopoietic cells

Xiaoping Sun, Enze Wang, Daniel M. Jones, Haifa Shen, Marcella M. Johnson, Jean-Pierre J. Issa, Hesham Amin, Cheryl F. Ginsberg, Hagop M. Kantarjian, Michael Andreeff, Steven M. Kornblau, Armand B. Glassman, Ralph B. Arlinghaus
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 714.
Published: 15 April 2006
View article titled, SOX4 gene expression in human leukemic and benign hematopoietic cells