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Steven C. Smith
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Journal Articles

PLK1 Induces Chromosomal Instability and Overrides Cell-Cycle Checkpoints to Drive Tumorigenesis

Lilia Gheghiani, Lei Wang, Youwei Zhang, Xavier T.R. Moore, Jinglei Zhang, Steven C. Smith, Yijun Tian, Liang Wang, Kristi Turner, Colleen K. Jackson-Cook, Nitai D. Mukhopadhyay, Zheng Fu
Journal: Cancer Research
Cancer Res (2021) 81 (5): 1293–1307.
https://doi.org/10.1158/0008-5472.CAN-20-1377
Published: 01 March 2021
View article titled, PLK1 Induces Chromosomal Instability and Overrides Cell-Cycle Checkpoints to Drive Tumorigenesis
Open the PDF for PLK1 Induces Chromosomal Instability and Overrides Cell-Cycle Checkpoints to Drive Tumorigenesis in another window
Includes: Multimedia, Supplementary data
Journal Articles

Abstract 2899: Significance of microRNA:target interaction in bladder cancer metastasis.

Yuanbin Ru, Katerina J. Kechris, Steven C. Smith, George A. Calin, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2899.
https://doi.org/10.1158/1538-7445.AM2013-2899
Published: 15 April 2013
View article titled, Abstract 2899: Significance of microRNA:target interaction in bladder cancer metastasis.
Journal Articles

CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis

Shibu Thomas, Michael A. Harding, Steven C. Smith, Jonathan B. Overdevest, Matthew D. Nitz, Henry F. Frierson, Scott A. Tomlins, Glen Kristiansen, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2012) 72 (21): 5600–5612.
https://doi.org/10.1158/0008-5472.CAN-11-3666
Published: 31 October 2012
View article titled, CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis
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Includes: Supplementary data
Journal Articles

Transcriptional Signatures of Ral GTPase Are Associated with Aggressive Clinicopathologic Characteristics in Human Cancer

Steven C. Smith, Alexander S. Baras, Charles R. Owens, Garrett Dancik, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2012) 72 (14): 3480–3491.
https://doi.org/10.1158/0008-5472.CAN-11-3966
Published: 15 July 2012
View article titled, Transcriptional Signatures of Ral GTPase Are Associated with Aggressive Clinicopathologic Characteristics in Human Cancer
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Includes: Supplementary data
Journal Articles

Abstract 3391: Interaction of microRNAs and target genes in bladder cancer metastasis

Yuanbin Ru, Katerina J. Kechris, Steven C. Smith, George A. Calin, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3391.
https://doi.org/10.1158/1538-7445.AM2012-3391
Published: 15 April 2012
View article titled, Abstract 3391: Interaction of microRNAs and target genes in bladder cancer metastasis
Journal Articles

CD24 Offers a Therapeutic Target for Control of Bladder Cancer Metastasis Based on a Requirement for Lung Colonization

Jonathan B. Overdevest, Shibu Thomas, Glen Kristiansen, Donna E. Hansel, Steven C. Smith, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2011) 71 (11): 3802–3811.
https://doi.org/10.1158/0008-5472.CAN-11-0519
Published: 31 May 2011
View article titled, CD24 Offers a Therapeutic Target for Control of Bladder Cancer Metastasis Based on a Requirement for Lung Colonization
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Includes: Supplementary data
Journal Articles

Abstract 50: An informatic approach to rational selection of cell lines modeling complex clinicopathologic phenotypes based on gene expression: The COXEN algorithm

Steven C. Smith, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 50.
https://doi.org/10.1158/1538-7445.AM2011-50
Published: 15 April 2011
View article titled, Abstract 50: An informatic approach to rational selection of cell lines modeling complex clinicopathologic phenotypes based on gene expression: The COXEN algorithm
Journal Articles

Abstract 5063: Signatures of Ral GTPase status define key clinicopathologic characteristics and outcomes in cancer

Steven C. Smith, Alexander S. Baras, Hong Wang, Charles R. Owens, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5063.
https://doi.org/10.1158/1538-7445.AM10-5063
Published: 15 April 2010
View article titled, Abstract 5063: Signatures of Ral GTPase status define key clinicopathologic characteristics and outcomes in cancer
Journal Articles

Abstract 747: Development and evaluation of rational combination therapy with imidazoacridinones for human bladder cancer patients through the COXEN algorithm

Steven C. Smith, Dmytro Havaleshko, Kihyuck Moon, Alexander S. Baras, Stefan Bekiranov, Daniel J. Burke, Jae K. Lee, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 747.
https://doi.org/10.1158/1538-7445.AM10-747
Published: 15 April 2010
View article titled, Abstract 747: Development and evaluation of rational combination therapy with imidazoacridinones for human bladder cancer patients through the COXEN algorithm
Journal Articles

Abstract LB-65: A gene expression predictor of pathological node stage of urothelial bladder cancer

Steven C. Smith, Alexander Spyridon Baras, Kuan-Fu Ding, Arndt Hartmann, Yves Fradet, Christopher Moskaluk, Jae K. Lee, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): LB-65.
https://doi.org/10.1158/1538-7445.AM10-LB-65
Published: 15 April 2010
View article titled, Abstract LB-65: A gene expression predictor of pathological node stage of urothelial bladder cancer
Journal Articles

The COXEN Principle: Translating Signatures of In vitro Chemosensitivity into Tools for Clinical Outcome Prediction and Drug Discovery in Cancer

Steven C. Smith, Alexander S. Baras, Jae K. Lee, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2010) 70 (5): 1753–1758.
https://doi.org/10.1158/0008-5472.CAN-09-3562
Published: 28 February 2010
View article titled, The COXEN Principle: Translating Signatures of <em>In vitro</em> Chemosensitivity into Tools for Clinical Outcome Prediction and Drug Discovery in Cancer
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Journal Articles

Transcriptional regulation in human bladder cancer cells by RalA and RalB via both independent and overlapping pathways

Gary Oxford, Steven C. Smith, Tonia L. Foreman, Charles R. Owens, Garret M. Hampton, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1004.
Published: 15 April 2006
View article titled, Transcriptional regulation in human bladder cancer cells by RalA and RalB via both independent and overlapping pathways
Journal Articles

Same seed, different soil: Comparative analysis of the metastatic tropism of bladder cancer

Steven C. Smith, Alexander Baras, Brian Nicholson, Garret Hampton, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1012.
Published: 15 April 2006
View article titled, Same seed, different soil: Comparative analysis of the metastatic tropism of bladder cancer
Journal Articles

Serum Response Factor regulates expression of the Rhogdi2 metastasis suppressor gene in bladder cancer cells

Michael A. Harding, Brian J. Titus, Steven C. Smith, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 27–28.
Published: 15 April 2006
View article titled, Serum Response Factor regulates expression of the Rhogdi2 metastasis suppressor gene in bladder cancer cells
Journal Articles

The Metastasis-Associated Gene CD24 Is Regulated by Ral GTPase and Is a Mediator of Cell Proliferation and Survival in Human Cancer

Steven C. Smith, Gary Oxford, Zhong Wu, Matthew D. Nitz, Mark Conaway, Henry F. Frierson, Garret Hampton, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2006) 66 (4): 1917–1922.
https://doi.org/10.1158/0008-5472.CAN-05-3855
Published: 17 February 2006
View article titled, The Metastasis-Associated Gene <em>CD24</em> Is Regulated by Ral GTPase and Is a Mediator of Cell Proliferation and Survival in Human Cancer
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Journal Articles

RalA and RalB: Antagonistic Relatives in Cancer Cell Migration

Gary Oxford, Charles R. Owens, Brian J. Titus, Tonia L. Foreman, Mikael C. Herlevsen, Steven C. Smith, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2005) 65 (16): 7111–7120.
https://doi.org/10.1158/0008-5472.CAN-04-1957
Published: 15 August 2005
View article titled, RalA and RalB: Antagonistic Relatives in Cancer Cell Migration
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