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Stephen S. Hecht
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Journal Articles

Abstract 7665: Detection of γ-OHPdG as a hepatocellular carcinoma recurrence biomarker by CTCs and LC-MS/MS

Mark Kuo, Merve Ozge Aktop, Elie Ghabi, Mahmoud A. Ouf, Margaret Carder, Vinona Muralidaran, Jhalen Ascue, Marketa Hlouskova, Pengfei Wu, Guang Cheng, Stephen S. Hecht, Hong-Bin Fang, Nader Hanna, Jin He, Alexander H. Kroemer, Monika Aggarwal, Aiwu R. He, Fung-Lung Chung
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7665.
https://doi.org/10.1158/1538-7445.AM2024-7665
Published: 22 March 2024
View article titled, Abstract 7665: Detection of γ-OHPdG as a hepatocellular carcinoma recurrence biomarker by CTCs and LC-MS/MS
Journal Articles

Abstract 2681: Prediagnostic levels of urinary 8-epi-prostaglandin F2α and prostaglandin E2 metabolite, biomarkers of oxidative damage and inflammation, and risk of hepatocellular carcinoma

Jian-Min Yuan, Menno Grouls, Steven G. Carmella, Renwei Wang, Alicia Heskin, Yang Jiang, Yuting Tan, Jennifer Adams-Haduch, Yu-Tang Gao, Stephen S. Hecht
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2681.
https://doi.org/10.1158/1538-7445.AM2019-2681
Published: 01 July 2019
View article titled, Abstract 2681: Prediagnostic levels of urinary 8-<em>epi</em>-prostaglandin F<sub>2α</sub> and prostaglandin E<sub>2</sub> metabolite, biomarkers of oxidative damage and inflammation, and risk of hepatocellular carcinoma
Journal Articles

Abstract 4347: A randomized phase 2 clinical trial of PEITC on detoxification of tobacco-specific and non-specific carcinogens and toxicants

Jian-Min Yuan, Jian-Min Yuan, Irina Stepanov, Sharon E. Murphy, Sharon E. Murphy, Renwei Wang, Steven G. Carmella, Heather H. Nelson, Heather H. Nelson, Dorothy Hatsukami, Stephen S. Hecht
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4347.
https://doi.org/10.1158/1538-7445.AM2016-4347
Published: 15 July 2016
View article titled, Abstract 4347: A randomized phase 2 clinical trial of PEITC on detoxification of tobacco-specific and non-specific carcinogens and toxicants
Journal Articles

Abstract 4595: The impact of CYP2A6 genetic polymorphisms on nicotine metabolism and lung cancer risk in two prospective cohorts of smokers

Jian-Min Yuan, Heather H. Nelson, Lesley M. Butler, Steven G. Carmella, Renwei Wang, Jennifer Adams-Haduch, Stephen S. Hecht, Woon-Puay Koh, Yu-Tang Gao, Sharon E. Murphy
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4595.
https://doi.org/10.1158/1538-7445.AM2015-4595
Published: 01 August 2015
View article titled, Abstract 4595: The impact of CYP2A6 genetic polymorphisms on nicotine metabolism and lung cancer risk in two prospective cohorts of smokers
Journal Articles

Abstract 4152: Differences in nicotine metabolism among five racial/ethnic groups with disparate risks for lung cancer: The multiethnic cohort study

Sung-Shim L. Park, Christian Caberto, Maarit Tiirikainen, Lynne Wilkens, Daniel Stram, Christopher A. Haiman, Stephen S. Hecht, Sharon Murphy, Loic L. Marchand
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4152.
https://doi.org/10.1158/1538-7445.AM2014-4152
Published: 01 October 2014
View article titled, Abstract 4152: Differences in nicotine metabolism among five racial/ethnic groups with disparate risks for lung cancer: The multiethnic cohort study
Journal Articles

Urinary Tobacco Smoke–Constituent Biomarkers for Assessing Risk of Lung Cancer

Jian-Min Yuan, Lesley M. Butler, Irina Stepanov, Stephen S. Hecht
Journal: Cancer Research
Cancer Res (2014) 74 (2): 401–411.
https://doi.org/10.1158/0008-5472.CAN-13-3178
Published: 16 January 2014
View article titled, Urinary Tobacco Smoke–Constituent Biomarkers for Assessing Risk of Lung Cancer
Open the PDF for Urinary Tobacco Smoke–Constituent Biomarkers for Assessing Risk of Lung Cancer in another window
Journal Articles

Abstract 1502: Urinary biomarkers of polycyclic aromatic hydrocarbon and volatile organic carcinogens in relation to lung cancer development in lifelong never smokers - The Shanghai Cohort Study.

Jian-Min Yuan, Yu-Tang Gao, Sharon Murphy, Steven G. Carmella, Renwei Wang, Heather H. Nelson, Stephen S. Hecht
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1502.
https://doi.org/10.1158/1538-7445.AM2013-1502
Published: 15 April 2013
View article titled, Abstract 1502: Urinary biomarkers of polycyclic aromatic hydrocarbon and volatile organic carcinogens in relation to lung cancer development in lifelong never smokers - The Shanghai Cohort Study.
Journal Articles

Abstract 667: Evaluation of toxicant exposure in U.S. smokers after short-term switching to commercial low-nitrosamine cigarettes

Aleksandar Knezevich, Jian-Min Yuan, Steven Carmella, Dorothy Hatsukami, Stephen S. Hecht, Irina Stepanov
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 667.
https://doi.org/10.1158/1538-7445.AM2012-667
Published: 15 April 2012
View article titled, Abstract 667: Evaluation of toxicant exposure in U.S. smokers after short-term switching to commercial low-nitrosamine cigarettes
Journal Articles

Abstract 4791: Development of a high resolution mass spectrometry method for the observation and characterization of unknown adducts in human DNA

Silvia Balbo, Peter W. Villalta, Stephen S. Hecht
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4791.
https://doi.org/10.1158/1538-7445.AM2012-4791
Published: 15 April 2012
View article titled, Abstract 4791: Development of a high resolution mass spectrometry method for the observation and characterization of unknown adducts in human DNA
Journal Articles

Abstract LB-63: (S)-N′-nitrosonornicotine, a constituent of smokeless tobacco, is a potent oral tumorigen in rats

Silvia Balbo, Sandra James-Yi, M. Gerard O'Sullivan, Irina Stepanov, Mingyao Wang, Siyi Zhang, Fekadu Kassie, Steven Carmella, Courtney Wettlaufer, Kelsey Hohol, Aleks Knezevich, Pramod Upadhyaya, Stephen S. Hecht
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-63.
https://doi.org/10.1158/1538-7445.AM2012-LB-63
Published: 15 April 2012
View article titled, Abstract LB-63: (S)-<em>N′</em>-nitrosonornicotine, a constituent of smokeless tobacco, is a potent oral tumorigen in rats
Journal Articles

Urinary Levels of Cigarette Smoke Constituent Metabolites Are Prospectively Associated with Lung Cancer Development in Smokers

Jian-Min Yuan, Yu-Tang Gao, Sharon E. Murphy, Steven G. Carmella, Renwei Wang, Yan Zhong, Kristin A. Moy, Andrew B. Davis, Li Tao, Menglan Chen, Shaomei Han, Heather H. Nelson, Mimi C. Yu, Stephen S. Hecht
Journal: Cancer Research
Cancer Res (2011) 71 (21): 6749–6757.
https://doi.org/10.1158/0008-5472.CAN-11-0209
Published: 30 October 2011
View article titled, Urinary Levels of Cigarette Smoke Constituent Metabolites Are Prospectively Associated with Lung Cancer Development in Smokers
Open the PDF for Urinary Levels of Cigarette Smoke Constituent Metabolites Are Prospectively Associated with Lung Cancer Development in Smokers in another window
Journal Articles

Abstract 3167: Comparison of the pharmacokinetics of phenanthrene in smokers after oral ingestion or inhalation through cigarettes for potential lung cancer susceptibility assessment

Yan Zhong, Jing Wang, Steven G. Carmella, Pramod Upadhyaya, Diane Rauch, Andrew Oliver, Joni Jensen, Dorothy Hatsukami, Cheryl Zimmerman, Stephen S. Hecht
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3167.
https://doi.org/10.1158/1538-7445.AM2011-3167
Published: 15 April 2011
View article titled, Abstract 3167: Comparison of the pharmacokinetics of phenanthrene in smokers after oral ingestion or inhalation through cigarettes for potential lung cancer susceptibility assessment
Journal Articles

Abstract 3731: A prospective evaluation of dietary indole-3-carbinol in relation to risk of breast cancer in the Singapore Chinese Health Study

Kristin A. Moy, Woon-Puay Koh, Renwei Wang, Stephen S. Hecht, Mimi C. Yu, Jian-Min Yuan
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3731.
https://doi.org/10.1158/1538-7445.AM2011-3731
Published: 15 April 2011
View article titled, Abstract 3731: A prospective evaluation of dietary indole-3-carbinol in relation to risk of breast cancer in the Singapore Chinese Health Study
Journal Articles

Abstract 2758: Genetic variability in tobacco-specific nitrosamine NNK to NNAL metabolism

Monica Ter-Minassian, Kofi Asomaning, Yang Zhao, Feng Chen, Li Su, Steven G. Carmella, Xihong Lin, Stephen S. Hecht, David C. Christiani
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2758.
https://doi.org/10.1158/1538-7445.AM2011-2758
Published: 15 April 2011
View article titled, Abstract 2758: Genetic variability in tobacco-specific nitrosamine NNK to NNAL metabolism
Journal Articles

Abstract 4651: Analysis of 3,3′-diindolylmethane in urine after consumption of cruciferous vegetables in the Singapore Cohort Study

Pramod Upadhyaya, Kristin Moy, Woon-Puay Koh, Stephen S. Hecht, Jian-Min Yuan
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4651.
https://doi.org/10.1158/1538-7445.AM2011-4651
Published: 15 April 2011
View article titled, Abstract 4651: Analysis of 3,3′-diindolylmethane in urine after consumption of cruciferous vegetables in the Singapore Cohort Study
Journal Articles

Abstract 4650: Nornicotine nitrosation in human saliva and its relation to endogenous formation of N′-nitrosonornicotine in oral nicotine replacement therapy users

Irina Stepanov, Aleksandar Knezevich, John Muzic, Dorothy K. Hatsukami, Stephen S. Hecht
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4650.
https://doi.org/10.1158/1538-7445.AM2011-4650
Published: 15 April 2011
View article titled, Abstract 4650: Nornicotine nitrosation in human saliva and its relation to endogenous formation of N′-nitrosonornicotine in oral nicotine replacement therapy users
Journal Articles

Abstract 4652: Urinary levels of the tobacco-specific carcinogen N′-nitrosonornicotine and its glucuronide are strongly associated with esophageal cancer risk in smokers in the Shanghai Cohort Study

Jian-Min Yuan, Aleksandar D. Knezevich, Renwei Wang, Yu-Tang Gao, Stephen S. Hecht, Irina Stepanov
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4652.
https://doi.org/10.1158/1538-7445.AM2011-4652
Published: 15 April 2011
View article titled, Abstract 4652: Urinary levels of the tobacco-specific carcinogen N′-nitrosonornicotine and its glucuronide are strongly associated with esophageal cancer risk in smokers in the Shanghai Cohort Study
Journal Articles

Abstract 4639: Effects of defined amounts of alcohol consumption on levels of N2-ethylidene-dGuo in DNA from human buccal cells and peripheral blood nucleated cells

Silvia Balbo, Lei Meng, Joni A. Jensen, Dorothy K. Hatsukami, Stephen S. Hecht
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4639.
https://doi.org/10.1158/1538-7445.AM2011-4639
Published: 15 April 2011
View article titled, Abstract 4639: Effects of defined amounts of alcohol consumption on levels of N<sup>2</sup>-ethylidene-dGuo in DNA from human buccal cells and peripheral blood nucleated cells
Journal Articles

Abstract 4656: Relationship of nicotine and carcinogen biomarkers to lung cancer risk among smokers in the Shanghai cohort study

Sharon E. Murphy, Jeannette Zinggeler Berg, Renwei Wang, Katherine M. Wickham, Yu-Tang Gao, Stephen S. Hecht, Jian-Min Yuan
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4656.
https://doi.org/10.1158/1538-7445.AM2011-4656
Published: 15 April 2011
View article titled, Abstract 4656: Relationship of nicotine and carcinogen biomarkers to lung cancer risk among smokers in the Shanghai cohort study
Journal Articles

Abstract LB-405: Modulation of the metabolism of air-borne pollutants by broccoli sprout beverages: Results of a short term, cross-over clinical trial in Qidong, People's Republic of China

Patricia A. Egner, Jian Guo Chen, Jin Bing Wang, Marlin D. Friesen, Lisa P. Jacobson, Alvaro Munoz, Derek Ng, Tao Yang Chen, Jed W. Fahey, Paul Talalay, Steven G. Carmella, Stephen S. Hecht, John D. Groopman, Thomas W. Kensler
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-405.
https://doi.org/10.1158/1538-7445.AM2011-LB-405
Published: 15 April 2011
View article titled, Abstract LB-405: Modulation of the metabolism of air-borne pollutants by broccoli sprout beverages: Results of a short term, cross-over clinical trial in Qidong, People's Republic of China