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MYC Inhibition Depletes Cancer Stem-like Cells in Triple-Negative Breast Cancer

Aimin Yang, Shenghui Qin, Bradley A. Schulte, Stephen P. Ethier, Kenneth D. Tew, Gavin Y. Wang

Cancer Res (2017) 77 (23): 6641–6650.

DOI: https://doi.org/10.1158/0008-5472.CAN-16-3452

Published: 30 November 2017

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Includes: Supplementary data

Journal Articles

Abstract 1339: Role of PTEN loss in basal-like 2 triple negative breast cancer

Ericka L. Smith, Christiana S. Kappler, Stephen P. Ethier

Cancer Res (2017) 77 (13_Supplement): 1339.

DOI: https://doi.org/10.1158/1538-7445.AM2017-1339

Published: 01 July 2017

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Journal Articles

Abstract 1835: Development of mammary hyperplasia, dysplasia, and invasive ductal carcinoma in transgenic mice expressing the 8p11 amplicon oncogene NSD3 (WHSC1L1)

Alex C. Rutkovsky, Brittany Turner-Ivey, Ericka L. Smith, Laura S. Spruill, Jamie N. Mills, Stephen P. Ethier

Cancer Res (2017) 77 (13_Supplement): 1835.

DOI: https://doi.org/10.1158/1538-7445.AM2017-1835

Published: 01 July 2017

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Journal Articles

Abstract 1919: Twist1 modulates paclitaxel-induced cancer stem cell enrichment in triple-negative breast cancer

Aimin Yang, Xiaoyuan He, Bradley A. Schulte, Steven L. Carroll, Stephen P. Ethier, Gavin Y. Wang

Cancer Res (2017) 77 (13_Supplement): 1919.

DOI: https://doi.org/10.1158/1538-7445.AM2017-1919

Published: 01 July 2017

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Journal Articles

Abstract 2405: The 8p11 amplicon oncogenes ASH2L and NSD3 alter the epigenomic landscape and provide the foundation for novel application of epigenetic therapy in luminal B breast cancers

Jamie N. Mills, Stephen P. Ethier

Cancer Res (2017) 77 (13_Supplement): 2405.

DOI: https://doi.org/10.1158/1538-7445.AM2017-2405

Published: 01 July 2017

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Journal Articles

Abstract LB-092: Induction of IL-17-mediated cellular immunity targeting MUC1 through vaccination

Amanda C. LaRue, Rebecca Carrell, Lindsay T. McDonald, Dayvia A. Russell, Stephen P. Ethier, Adam C. Soloff

Cancer Res (2016) 76 (14_Supplement): LB-092.

DOI: https://doi.org/10.1158/1538-7445.AM2016-LB-092

Published: 15 July 2016

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Journal Articles

MYC Is a Crucial Mediator of TGFβ-Induced Invasion in Basal Breast Cancer

Magdalena A. Cichon, Megan E. Moruzzi, Tiziana A. Shqau, Erin Miller, Christine Mehner, Stephen P. Ethier, John A. Copland, Evette S. Radisky, Derek C. Radisky

Cancer Res (2016) 76 (12): 3520–3530.

DOI: https://doi.org/10.1158/0008-5472.CAN-15-3465

Published: 14 June 2016

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Includes: Supplementary data

Journal Articles

Abstract B05: WHSC1L1 and estrogen-independent activation of estrogen receptor-alpha (ERα) in 8p11 amplicon-bearing cell lines

Jamie N. Mills, Jonathan Irish, Brittany Turner-Ivey, Stephen P. Ethier

Cancer Res (2016) 76 (2_Supplement): B05.

DOI: https://doi.org/10.1158/1538-7445.CHROMEPI15-B05

Published: 14 January 2016

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Journal Articles

Abstract 3297: PTEN loss enhances amphiregulin-specific signaling and gene expression in triple-negative breast cancer

Christiana Kappler, Robert Wilson, Bridget Varughese, Stephen P. Ethier

Cancer Res (2014) 74 (19_Supplement): 3297.

DOI: https://doi.org/10.1158/1538-7445.AM2014-3297

Published: 01 October 2014

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Journal Articles

Abstract 5135: A chromatin modifier from the 8p11 amplicon in luminal breast cancer

Brittany Turner Ivey, Steve Guest, Stephen P. Ethier

Cancer Res (2014) 74 (19_Supplement): 5135.

DOI: https://doi.org/10.1158/1538-7445.AM2014-5135

Published: 01 October 2014

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Journal Articles

Abstract 5148: Overexpression of histone methyltransferase WHSC1L1 regulates expression of ER-alpha in SUM44 breast cancer cells

Jonathan Curtis Irish, Alexandria Rutkovsky, Stephen P. Ethier

Cancer Res (2014) 74 (19_Supplement): 5148.

DOI: https://doi.org/10.1158/1538-7445.AM2014-5148

Published: 01 October 2014

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Journal Articles

Abstract 2964: Epigenetic mechanisms of transformation by WHSC1L1 in breast cancer cells with the 8p11-p12 amplicon.

Jonathan C. Irish, Gang Liu, Stephen P. Ethier

Cancer Res (2013) 73 (8_Supplement): 2964.

DOI: https://doi.org/10.1158/1538-7445.AM2013-2964

Published: 15 April 2013

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Journal Articles

Abstract 530: Inhibition of amphiregulin-mediated EGFR signaling suppresses tumorigenicity in breast cancer cells.

Christiana S. Kappler, Stephen P. Ethier

Cancer Res (2013) 73 (8_Supplement): 530.

DOI: https://doi.org/10.1158/1538-7445.AM2013-530

Published: 15 April 2013

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Journal Articles

Abstract 3248: Amphiregulin interacts with Wnt signaling to regulate cancer cell growth and survival

Bridget Elsa Varughese, Stephen P. Ethier

Cancer Res (2012) 72 (8_Supplement): 3248.

DOI: https://doi.org/10.1158/1538-7445.AM2012-3248

Published: 15 April 2012

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Journal Articles

Abstract 2190: Epigenetic mechanisms of transformation for the NSD3 oncogene in human breast cancer cells with the 8p11-p12 amplicon

Jonathan C. Irish, Stephen P. Ethier

Cancer Res (2012) 72 (8_Supplement): 2190.

DOI: https://doi.org/10.1158/1538-7445.AM2012-2190

Published: 15 April 2012

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Journal Articles

Abstract 5099: Identification of complex oncogene signatures in human cancer specimens and cell lines

Govindaraja Atikukke, Ramsi Haddad, Stephen P. Ethier

Cancer Res (2012) 72 (8_Supplement): 5099.

DOI: https://doi.org/10.1158/1538-7445.AM2012-5099

Published: 15 April 2012

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Journal Articles

Abstract 1135: PPAPDC1B isoform 2, a new candidate oncogene within the 8p11-12 amplicon induces a proliferative advantage in breast cancer

Gang Liu, Zeng-Quan Yang, Stephen P. Ethier

Cancer Res (2011) 71 (8_Supplement): 1135.

DOI: https://doi.org/10.1158/1538-7445.AM2011-1135

Published: 15 April 2011

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Journal Articles

Abstract 3441: Cross-species expression profiling identifies Forkhead-Box Q1 as a promoter of epithelial-mesenchymal transition and breast cancer metastasis

Haijun Zhang, Fanyan Meng, Gang Liu, Bin Zhang, Jun Zhu, Feng Wu, Stephen P. Ethier, Fred Miller, Guojun Wu

Cancer Res (2011) 71 (8_Supplement): 3441.

DOI: https://doi.org/10.1158/1538-7445.AM2011-3441

Published: 15 April 2011

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Journal Articles

Forkhead Transcription Factor Foxq1 Promotes Epithelial–Mesenchymal Transition and Breast Cancer Metastasis

Haijun Zhang, Fanyan Meng, Gang Liu, Bin Zhang, Jun Zhu, Feng Wu, Stephen P. Ethier, Fred Miller, Guojun Wu

Cancer Res (2011) 71 (4): 1292–1301.

DOI: https://doi.org/10.1158/0008-5472.CAN-10-2825

Published: 14 February 2011

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Includes: Supplementary data

Journal Articles

Transforming Properties of 8p11-12 Amplified Genes in Human Breast Cancer

Zeng-Quan Yang, Gang Liu, Aliccia Bollig-Fischer, Craig N. Giroux, Stephen P. Ethier

Cancer Res (2010) 70 (21): 8487–8497.

DOI: https://doi.org/10.1158/0008-5472.CAN-10-1013

Published: 31 October 2010

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Includes: Supplementary data

2 3 4

NARROW

MYC Inhibition Depletes Cancer Stem-like Cells in Triple-Negative Breast Cancer

Abstract 1339: Role of PTEN loss in basal-like 2 triple negative breast cancer

Abstract 1835: Development of mammary hyperplasia, dysplasia, and invasive ductal carcinoma in transgenic mice expressing the 8p11 amplicon oncogene NSD3 (WHSC1L1)

Abstract 1919: Twist1 modulates paclitaxel-induced cancer stem cell enrichment in triple-negative breast cancer

Abstract 2405: The 8p11 amplicon oncogenes ASH2L and NSD3 alter the epigenomic landscape and provide the foundation for novel application of epigenetic therapy in luminal B breast cancers

Abstract LB-092: Induction of IL-17-mediated cellular immunity targeting MUC1 through vaccination

MYC Is a Crucial Mediator of TGFβ-Induced Invasion in Basal Breast Cancer

Abstract B05: WHSC1L1 and estrogen-independent activation of estrogen receptor-alpha (ERα) in 8p11 amplicon-bearing cell lines

Abstract 3297: PTEN loss enhances amphiregulin-specific signaling and gene expression in triple-negative breast cancer

Abstract 5135: A chromatin modifier from the 8p11 amplicon in luminal breast cancer

Abstract 5148: Overexpression of histone methyltransferase WHSC1L1 regulates expression of ER-alpha in SUM44 breast cancer cells

Abstract 2964: Epigenetic mechanisms of transformation by WHSC1L1 in breast cancer cells with the 8p11-p12 amplicon.

Abstract 530: Inhibition of amphiregulin-mediated EGFR signaling suppresses tumorigenicity in breast cancer cells.

Abstract 3248: Amphiregulin interacts with Wnt signaling to regulate cancer cell growth and survival

Abstract 2190: Epigenetic mechanisms of transformation for the NSD3 oncogene in human breast cancer cells with the 8p11-p12 amplicon

Abstract 5099: Identification of complex oncogene signatures in human cancer specimens and cell lines

Abstract 1135: PPAPDC1B isoform 2, a new candidate oncogene within the 8p11-12 amplicon induces a proliferative advantage in breast cancer

Abstract 3441: Cross-species expression profiling identifies Forkhead-Box Q1 as a promoter of epithelial-mesenchymal transition and breast cancer metastasis

Forkhead Transcription Factor Foxq1 Promotes Epithelial–Mesenchymal Transition and Breast Cancer Metastasis

Transforming Properties of 8p11-12 Amplified Genes in Human Breast Cancer

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