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Stephen M. Hewitt
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Journal Articles

Abstract LB062: Profiling of pediatric neuroblastoma reveals a dynamic and clinically significant tumor immune microenvironment

Katherine E. Masih, Zahin Islam, Paul Aiyetan, Igor B. Kuznetsov, Stephen M. Hewitt, Daniel Catchpoole, Jun S. Wei, William Bocik, Javed Khan
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): LB062.
https://doi.org/10.1158/1538-7445.AM2022-LB062
Published: 15 June 2022
View article titled, Abstract LB062: Profiling of pediatric neuroblastoma reveals a dynamic and clinically significant tumor immune microenvironment
Journal Articles

Abstract LB213: Potent antitumor activity of a FGFR4 CAR-T in rhabdomyosarcoma

Adam Tai Chi Cheuk, Meijie Tian, Nityashree Shivaprasad, Steven Highfill, David Milewski, G Tom Brown, Peter Azorsa, Dina Schneider, Berkley Gryder, Jun S Wei, Young Kwok Song, Hsien-Chao Chou, Jerry Wu, Joon-Yong Chung, Brian Belyea, Corinne Linardic, Stephen M Hewitt, Boro Dropulic, Rimas Orentas, Javed Khan
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): LB213.
https://doi.org/10.1158/1538-7445.AM2022-LB213
Published: 15 June 2022
View article titled, Abstract LB213: Potent antitumor activity of a FGFR4 CAR-T in rhabdomyosarcoma
Journal Articles

Abstract 3970: Tumor-associated macrophage, angiogenesis and lymphangiogenesis predicts prognosis in patients with non-small cell lung cancer

Ilseon Hwang, Keun Uk Park, Eun Hee Jung, Hun-Mo Ryoo, Kris Ylaya, Joon-Yong Chung, Stephen M. Hewitt
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3970.
https://doi.org/10.1158/1538-7445.AM2020-3970
Published: 15 August 2020
View article titled, Abstract 3970: Tumor-associated macrophage, angiogenesis and lymphangiogenesis predicts prognosis in patients with non-small cell lung cancer
Journal Articles

Abstract 4311: PPIB expression associates with tumor progression and unfavorable disease-free survival of non-small cell lung cancer

Jeongwon Kim, Joon-Yong Chung, Stephen M. Hewitt, Ilseon Hwang, Joon Seon Song, Chang-Min Choi, Eunho Cho, Kwon-Ho Song, Tae Woo Kim, Kris Ylaya
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4311.
https://doi.org/10.1158/1538-7445.AM2020-4311
Published: 15 August 2020
View article titled, Abstract 4311: <em>PPIB</em> expression associates with tumor progression and unfavorable disease-free survival of non-small cell lung cancer
Journal Articles

Abstract 1500: Understanding tumor cell community and its evolution by single cell analysis in liver cancer

Lichun Ma, Maria O. Hernandez, Yongmei Zhao, Monika Mehta, Bao Tran, Michael Kelly, Zachary Rae, Jonathan M. Hernandez, Jeremy L. Davis, Sean P. Martin, David E. Kleiner, Stephen M. Hewitt, Kris Ylaya, Bradford J. Wood, Tim F. Greten, Xin Wei Wang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1500.
https://doi.org/10.1158/1538-7445.AM2020-1500
Published: 15 August 2020
View article titled, Abstract 1500: Understanding tumor cell community and its evolution by single cell analysis in liver cancer
Journal Articles

Correction: Molecular Chaperone HSP90 Is Necessary to Prevent Cellular Senescence via Lysosomal Degradation of p14ARF

Su Yeon Han, Aram Ko, Haruhisa Kitano, Chel Hun Choi, Min-Sik Lee, Jinho Seo, Junya Fukuoka, Soo-Youl Kim, Stephen M. Hewitt, Joon-Yong Chung, Jaewhan Song
Journal: Cancer Research
Cancer Res (2018) 78 (24): 6903.
https://doi.org/10.1158/0008-5472.CAN-18-3311
Published: 13 December 2018
View article titled, Correction: Molecular Chaperone HSP90 Is Necessary to Prevent Cellular Senescence via Lysosomal Degradation of p14ARF
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Journal Articles

Abstract 4237: Differences in the frequencies of tumor VHL mutation and HIF-2α expression between black and white patients with clear cell renal carcinoma

Catherine L. Callahan, Lee E. Moore, Petra Lenz, Kendra Schwartz, Julie Ruterbusch, Faith Davis, Wong-Ho Chow, W. Marston Linehan, Maria J. Merino, Stephen M. Hewitt, Nathaniel Rothman, Jonathan N. Hofmann, Michael L. Nickerson, Mark P. Purdue
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4237.
https://doi.org/10.1158/1538-7445.AM2018-4237
Published: 01 July 2018
View article titled, Abstract 4237: Differences in the frequencies of tumor <em>VHL</em> mutation and HIF-2α expression between black and white patients with clear cell renal carcinoma
Journal Articles

Abstract 3260: Utilizing digital pathology to understand breast epithelial characteristics of benign breast disease among women undergoing diagnostic image-guided breast biopsy

Maeve Mullooly, Samantha Puvanesarajah, Shaoqi Fan, Ruth M. Pfeiffer, Linnea Olsson, Manila Hada, Erin L. Kirk, Pamela M. Vacek, Donald L. Weaver, John A. Shepherd, Amir P. Mahmoudzadeh, Jeff Wang, Stephen M. Hewitt, Sally D. Herschorn, Mark E. Sherman, Melissa A. Troester, Gretchen L. Gierach
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3260.
https://doi.org/10.1158/1538-7445.AM2018-3260
Published: 01 July 2018
View article titled, Abstract 3260: Utilizing digital pathology to understand breast epithelial characteristics of benign breast disease among women undergoing diagnostic image-guided breast biopsy
Journal Articles

Targeting Cyclin D-CDK4/6 Sensitizes Immune-Refractory Cancer by Blocking the SCP3–NANOG Axis

Se Jin Oh, Hanbyoul Cho, Suhyun Kim, Kyung Hee Noh, Kwon-Ho Song, Hyo-Jung Lee, Seon Rang Woo, Suyeon Kim, Chel Hun Choi, Joon-Yong Chung, Stephen M. Hewitt, Jae-Hoon Kim, Seungki Baek, Kyung-Mi Lee, Cassian Yee, Hae-Chul Park, Tae Woo Kim
Journal: Cancer Research
Cancer Res (2018) 78 (10): 2638–2653.
https://doi.org/10.1158/0008-5472.CAN-17-2325
Published: 14 May 2018
View article titled, Targeting Cyclin D-CDK4/6 Sensitizes Immune-Refractory Cancer by Blocking the SCP3–NANOG Axis
Open the PDF for Targeting Cyclin D-CDK4/6 Sensitizes Immune-Refractory Cancer by Blocking the SCP3–NANOG Axis in another window
Includes: Supplementary data
Journal Articles

HDAC1 Upregulation by NANOG Promotes Multidrug Resistance and a Stem-like Phenotype in Immune Edited Tumor Cells

Kwon-Ho Song, Chel Hun Choi, Hyo-Jung Lee, Se Jin Oh, Seon Rang Woo, Soon-Oh Hong, Kyung Hee Noh, Hanbyoul Cho, Eun Joo Chung, Jae-Hoon Kim, Joon-Yong Chung, Stephen M. Hewitt, Seungki Baek, Kyung-Mi Lee, Cassian Yee, Minjoo Son, Chih-Ping Mao, T.C. Wu, Tae Woo Kim
Journal: Cancer Research
Cancer Res (2017) 77 (18): 5039–5053.
https://doi.org/10.1158/0008-5472.CAN-17-0072
Published: 14 September 2017
View article titled, HDAC1 Upregulation by NANOG Promotes Multidrug Resistance and a Stem-like Phenotype in Immune Edited Tumor Cells
Open the PDF for HDAC1 Upregulation by NANOG Promotes Multidrug Resistance and a Stem-like Phenotype in Immune Edited Tumor Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 4390: The Thailand initiative in genomics and expression research in liver cancer: Race related common molecular subtypes among Asian hepatocellular carcinoma and cholangiocarcinoma identified by integrated genomics

Anuradha Budhu, Jittiporn Chaisaingmongkol, Hien Dang, Siritida Rabibhadana, Benjarath Pupacdi, So Mee Kwon, Marshonna Forgues, Yotsawat Pomyen, Vajarabhongsa Bhudhisawasdi, Nirush Lertprasertsuke, Anon Chotirosniramit, Chawalit Pairojkul, Chirayu U. Auewarakul, Thaniya Sricharunrat, Kannika Phornphutkul, Suleeporn Sangrajrang, Maggie Cam, Ping He, Stephen M. Hewitt, Xiaolin Wu, Snorri S. Thorgeirsson, Joshua J. Waterfall, Yuelin J. Zhu, Jennifer Walling, Holly S. Stevenson, Daniel Edelman, Paul S. Meltzer, Christopher A. Loffredo, Robert H. Wiltrout, Curtis C. Harris, Chulabhorn Mahidol, Mathuros Ruchirawat, Xin W. Wang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4390.
https://doi.org/10.1158/1538-7445.AM2017-4390
Published: 01 July 2017
View article titled, Abstract 4390: The Thailand initiative in genomics and expression research in liver cancer: Race related common molecular subtypes among Asian hepatocellular carcinoma and cholangiocarcinoma identified by integrated genomics
Journal Articles

Abstract 747: An improved fixative for histomorphology, recovery of nuclic acids and proteins

Stephen M. Hewitt, Joon-Yong Chung, Candice Perry, Kris Ylaya, William M-A Smith, Robert A. Star
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 747.
https://doi.org/10.1158/1538-7445.AM2017-747
Published: 01 July 2017
View article titled, Abstract 747: An improved fixative for histomorphology, recovery of nuclic acids and proteins
Journal Articles

Abstract 5729: Loss of USP10 and p14ARF protein expression is associated with poor prognosis patients with small intestinal adenocarcinoma

Joon Seon Song, Hanbyoul Cho, Joon-Yong Chung, Ilseon Hwang, Hee Jin Lee, Seung-Mo Hong, Stephen M. Hewitt
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5729.
https://doi.org/10.1158/1538-7445.AM2017-5729
Published: 01 July 2017
View article titled, Abstract 5729: Loss of USP10 and p14ARF protein expression is associated with poor prognosis patients with small intestinal adenocarcinoma
Journal Articles

Molecular Chaperone HSP90 Is Necessary to Prevent Cellular Senescence via Lysosomal Degradation of p14ARF

Su Yeon Han, Aram Ko, Haruhisa Kitano, Chel Hun Choi, Min-Sik Lee, Jinho Seo, Junya Fukuoka, Soo-Youl Kim, Stephen M. Hewitt, Joon-Yong Chung, Jaewhan Song
Journal: Cancer Research
Cancer Res (2017) 77 (2): 343–354.
https://doi.org/10.1158/0008-5472.CAN-16-0613
Published: 16 January 2017
View article titled, Molecular Chaperone HSP90 Is Necessary to Prevent Cellular Senescence via Lysosomal Degradation of p14ARF
Open the PDF for Molecular Chaperone HSP90 Is Necessary to Prevent Cellular Senescence via Lysosomal Degradation of p14ARF in another window
Includes: Supplementary data
Journal Articles

Abstract 2461: Rhabdomyosarcoma tumors recur by a PAX3-FOXO1-independent mechanism in a human myoblast xenograft model

Puspa R. Pandey, Bishwanath Chatterjee, Javed Khan, Stephen M. Hewitt, Markku Martti Miettinen, Frederic G. Barr
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2461.
https://doi.org/10.1158/1538-7445.AM2016-2461
Published: 15 July 2016
View article titled, Abstract 2461: Rhabdomyosarcoma tumors recur by a PAX3-FOXO1-independent mechanism in a human myoblast xenograft model
Journal Articles

Abstract A1-09: Functional analysis of the chr13q22.1 pancreatic cancer risk locus suggests allele-specific effects on DIS3 expression with prognostic implications

Jason W. Hoskins, Abdisamad Ibrahim, Mickey Emmanuel, Sarah Manmiller, Jinping Jia, Hemang Parikh, Irene Collins, Kris Ylaya, Sean F. Altekruse, Stephen M. Hewitt, Gloria M. Petersen, Laufey T. Amundadottir
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_1): A1-09.
https://doi.org/10.1158/1538-7445.TRANSCAGEN-A1-09
Published: 15 November 2015
View article titled, Abstract A1-09: Functional analysis of the chr13q22.1 pancreatic cancer risk locus suggests allele-specific effects on DIS3 expression with prognostic implications
Journal Articles

Abstract LB-173: The Thailand initiative in genomics and expression research for liver cancer (TIGER-LC): Defining novel subtypes of hepatocellular carcinoma and cholangiocarcinoma

Jittiporn Chaisaingmongkol, Anuradha Budhu, Hien Dang, Siritida Rabibhadana, Benjarath Pupacdi, Marshonna Forgues, Vajarabhongsa Bhudhisawasdi, Nirush Lertprasertsuke, Anon Chotirosniramit, Chawalit Pairojkul, Chirayu U. Auewarakul, Thaniya Sricharunrat, Kannika Phornphutkul, Suleeporn Sangrajrang, Maggie Cam, Ping He, Stephen M. Hewitt, Xiaolin Wu, Snorri S. Thorgeirsson, Paul S. Meltzer, Christopher A. Loffredo, Robert H. Wiltrout, Curtis C. Harris, Chulabhorn Mahidol, Mathuros Ruchirawat, Xin W. Wang
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-173.
https://doi.org/10.1158/1538-7445.AM2015-LB-173
Published: 01 August 2015
View article titled, Abstract LB-173: The Thailand initiative in genomics and expression research for liver cancer (TIGER-LC): Defining novel subtypes of hepatocellular carcinoma and cholangiocarcinoma
Journal Articles

Abstract 5184: Synaptonemal complex protein 3 is associated with lymphangiogenesis in non-small cell lung cancer

Haruhisa Kitano, Joon-Yong Chung, Jun Hanaoka, Shuhei Inoue, Doki Yoshinori, Junya Fukuoka, Stephen M. Hewitt
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5184.
https://doi.org/10.1158/1538-7445.AM2015-5184
Published: 01 August 2015
View article titled, Abstract 5184: Synaptonemal complex protein 3 is associated with lymphangiogenesis in non-small cell lung cancer
Journal Articles

Abstract 2768: Relationships between mammographic density, microvessel density, and breast biopsy diagnosis

Ashley S. Felix, Petra Lenz, Ruth M. Pfeiffer, Stephen M. Hewitt, Jennifer Morris, Deesha Patel, Berta Geller, Pamela M. Vacek, Donald L. Weaver, Rachael E. Chicoine, John Shepherd, Amir P. Mahmoudzadeh, Jeff Wang, Bo Fan, Sally Herschorn, Jason Johnson, Louise A. Brinton, Mark E. Sherman, Gretchen L. Gierach
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2768.
https://doi.org/10.1158/1538-7445.AM2015-2768
Published: 01 August 2015
View article titled, Abstract 2768: Relationships between mammographic density, microvessel density, and breast biopsy diagnosis
Journal Articles

Abstract 3093: CDK4 amplification reduces sensitivity to CDK4/6 inhibition in fusion-positive rhabdomyosarcoma

Mary E. Olanich, Wenyue Sun, Stephen M. Hewitt, Zied Abdullaev, Svetlana D. Pack, Frederic G. Barr
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3093.
https://doi.org/10.1158/1538-7445.AM2015-3093
Published: 01 August 2015
View article titled, Abstract 3093: CDK4 amplification reduces sensitivity to CDK4/6 inhibition in fusion-positive rhabdomyosarcoma