1-20 of 57
Stephen Lam
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract 6524: Single-cell landscape of cancer-associated fibroblasts in immunotherapy resistance of hepatocellular carcinoma

Patrick Pak-Chun Wong, Jianquan Cao, Zhewen Xiong, Haoran Wu, Qin Cao, Bonan Chen, Ka-Fai To, Stephen Lam Chan, Wei Kang, Alfred Sze-Lok Cheng
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6524.
https://doi.org/10.1158/1538-7445.AM2024-6524
Published: 22 March 2024
View article titled, Abstract 6524: Single-cell landscape of cancer-associated fibroblasts in immunotherapy resistance of hepatocellular carcinoma
Journal Articles

Abstract 1426: Lipid-mediated epigenetic activation of PPAR-gamma signaling promotes immune-checkpoint resistance in hepatocellular carcinoma

Zhewen Xiong, Stephen Lam Chan, Jingying Zhou, Xuezhen Zeng, Weiqin Yang, Haoran Wu, Jianquan Cao, Jie-Ting Low, Michael Wing-Yan Chan, Kevin Yuk-Lap Yip, Joseph Jao-Yiu Sung, Alfred Sze-Lok Cheng
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1426.
https://doi.org/10.1158/1538-7445.AM2024-1426
Published: 22 March 2024
View article titled, Abstract 1426: Lipid-mediated epigenetic activation of PPAR-gamma signaling promotes immune-checkpoint resistance in hepatocellular carcinoma
Journal Articles

Abstract 1424: Epigenetic activation of tumoral IFNγresponse and pyroptosis overcomes immunotherapy resistance in hepatocellular carcinoma

Yalin Tu, Haoran Wu, Chengpeng Zhong, Zhewen Xiong, Jing Wang, Patrick Pak-Chun Wong, Weiqin Yang, Jiahuan Lu, Zhixian Liang, Shufen Chen, Lingyun Zhang, Siyun Chen, Jingying Zhou, Ka-Fai To, Joseph Jao-Yiu Sung, Stephen Lam Chan, David Kerr, Nick La Thangue, Alfred Sze-Lok Cheng
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1424.
https://doi.org/10.1158/1538-7445.AM2024-1424
Published: 22 March 2024
View article titled, Abstract 1424: Epigenetic activation of tumoral IFNγresponse and pyroptosis overcomes immunotherapy resistance in hepatocellular carcinoma
Journal Articles

CYP2A6 Activity and Cigarette Consumption Interact in Smoking-Related Lung Cancer Susceptibility

Mulong Du, Junyi Xin, Rui Zheng, Qianyu Yuan, Zhihui Wang, Hongliang Liu, Hanting Liu, Guoshuai Cai, Demetrius Albanes, Stephen Lam, Adonina Tardon, Chu Chen, Stig E. Bojesen, Maria Teresa Landi, Mattias Johansson, Angela Risch, Heike Bickeböller, H-Erich Wichmann, Gad Rennert, Susanne Arnold, Paul Brennan, John K. Field, Sanjay S. Shete, Loïc Le Marchand, Geoffrey Liu, Angeline S. Andrew, Lambertus A. Kiemeney, Shan Zienolddiny, Kjell Grankvist, Mikael Johansson, Neil E. Caporaso, Angela Cox, Yun-Chul Hong, Jian-Min Yuan, Matthew B. Schabath, Melinda C. Aldrich, Meilin Wang, Hongbing Shen, Feng Chen, Zhengdong Zhang, Rayjean J. Hung, Christopher I. Amos, Qingyi Wei, Philip Lazarus, David C. Christiani
Journal: Cancer Research
Cancer Res (2024) 84 (4): 616–625.
https://doi.org/10.1158/0008-5472.CAN-23-0900
Published: 15 February 2024
View article titled, CYP2A6 Activity and Cigarette Consumption Interact in Smoking-Related Lung Cancer Susceptibility
Open the PDF for CYP2A6 Activity and Cigarette Consumption Interact in Smoking-Related Lung Cancer Susceptibility in another window
Includes: Supplementary data
Journal Articles

Abstract CT008: Pembrolizumab (pembro) in combination with gemcitabine and cisplatin (gem/cis) for advanced biliary tract cancer (BTC): Phase 3 KEYNOTE-966 study

Robin Kate Kelley, Changhoon Yoo, Richard S. Finn, Junji Furuse, Zhenggang Ren, Thomas Yau, Heinz-Josef Klümpen, Stephen Lam Chan, Arndt Vogel, Masato Ozaka, Chris Verslype, Mohamed Bouattour, Joon Oh Park, Olga Barajas, Uwe Pelzer, Juan W. Valle, Li Yu, Usha Malhotra, Abby B. Siegel, Julien Edeline, Makoto Ueno
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT008.
https://doi.org/10.1158/1538-7445.AM2023-CT008
Published: 29 May 2023
View article titled, Abstract CT008: Pembrolizumab (pembro) in combination with gemcitabine and cisplatin (gem/cis) for advanced biliary tract cancer (BTC): Phase 3 KEYNOTE-966 study
Journal Articles

Abstract 3330: Development of a genome-wide multiomic atlas of early-stage lung cancer enables identification of novel methylation biomarkers for disease detection beyond TCGA

Revital Knirsh, Stephen Lam, Anna McGuire, Peter J. Mazzone, Stephen Deppen, Eric Grogan, Fabien Maldonado, Orna Savin, Shacade Danan, Sarah Zaouch, Nimrod Axelrad, Dvir Netanely, Aharona Shuali, Catherine A. Schnabel, Adam Wasserstrom, Danny Frumkin
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3330.
https://doi.org/10.1158/1538-7445.AM2023-3330
Published: 04 April 2023
View article titled, Abstract 3330: Development of a genome-wide multiomic atlas of early-stage lung cancer enables identification of novel methylation biomarkers for disease detection beyond TCGA
Journal Articles

Abstract 5434: Machine-learning-based epigenetic detection of early-stage lung cancers using the EpiCheck liquid biopsy platform

Dvir Netanely, Stephen Lam, Anna McGuire, Stephen Deppen, Eric Grogan, Fabien Maldonado, Michael Gieske, Joseph Seaman, Kimberly Rieger-Christ, Satish Kalanjeri, Luis Herrera, Nichole Tanner, Garrett B. Sherwood, Orna Savin, Shacade Danan, Sarah Zaouch, Nimrod Axelrad, Revital Knirsh, Ofir Shliefer, Keren Manor, Radha Duttagupta, Aharona Shuali, Peter J. Mazzone, Gerard A. Silvestri, Catherine A. Schnabel, Danny Frumkin, Adam Wasserstrom
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5434.
https://doi.org/10.1158/1538-7445.AM2023-5434
Published: 04 April 2023
View article titled, Abstract 5434: Machine-learning-based epigenetic detection of early-stage lung cancers using the EpiCheck liquid biopsy platform
Journal Articles

Abstract PO-006: CircRTN4 promotes pancreatic cancer progression through a novel circRNA-miRNA-lncRNA pathway and stabilizing epithelial-mesenchymal transition protein

Chi Hin Wong, Ut Kei Lou, Frederic Khe-Cheong Fung, Joanna H. M. Tong, Ka-Fai To, Stephen Lam Chan, Yangchao Chen
Journal: Cancer Research
Cancer Res (2021) 81 (22_Supplement): PO-006.
https://doi.org/10.1158/1538-7445.PANCA21-PO-006
Published: 15 November 2021
View article titled, Abstract PO-006: CircRTN4 promotes pancreatic cancer progression through a novel circRNA-miRNA-lncRNA pathway and stabilizing epithelial-mesenchymal transition protein
Journal Articles

Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model

Rayjean J. Hung, Matthew T. Warkentin, Yonathan Brhane, Nilanjan Chatterjee, David C. Christiani, Maria Teresa Landi, Neil E. Caporaso, Geoffrey Liu, Mattias Johansson, Demetrius Albanes, Loic Le Marchand, Adonina Tardon, Gad Rennert, Stig E. Bojesen, Chu Chen, John K. Field, Lambertus A. Kiemeney, Philip Lazarus, Shanbeth Zienolddiny, Stephen Lam, Angeline S. Andrew, Susanne M. Arnold, Melinda C. Aldrich, Heike Bickeböller, Angela Risch, Matthew B. Schabath, James D. McKay, Paul Brennan, Christopher I. Amos
Journal: Cancer Research
Cancer Res (2021) 81 (6): 1607–1615.
https://doi.org/10.1158/0008-5472.CAN-20-1237
Published: 15 March 2021
View article titled, Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model
Open the PDF for Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model in another window
Includes: Supplementary data
Journal Articles

Abstract 954: Adverse immunomodulatory effects of chemotherapy on myeloid-derived suppressor cell compromise immune-checkpoint blockade efficacy

Tsz Tung Kwong, Chi Hang Wong, Jing Ying Zhou, Alfred Sze Lok Cheng, Anthony Wing Hung Chan, Stephen Lam Chan
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 954.
https://doi.org/10.1158/1538-7445.AM2020-954
Published: 15 August 2020
View article titled, Abstract 954: Adverse immunomodulatory effects of chemotherapy on myeloid-derived suppressor cell compromise immune-checkpoint blockade efficacy
Journal Articles

Abstract 4151: STAT3 regulates chemo-resistance and cancer stemness in hepatocellular carcinoma

Carol Lee, Elaine Yee-Ling OR, Charing Ching-Ning Chong, Tan To Cheung, Iris Ming-Jing Xu, Linda Wing-Chi Ng, Marcus Hung-Lam Law, Peter Tin-Chung Li, Stephen Lam Chan, Anthony Wing-Hung Chan, Philip Chun Yeung, Kelvin Kwok-Chai Ng, Paul Bo-San Lai, Siu Tim Cheung
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4151.
https://doi.org/10.1158/1538-7445.AM2020-4151
Published: 15 August 2020
View article titled, Abstract 4151: STAT3 regulates chemo-resistance and cancer stemness in hepatocellular carcinoma
Journal Articles

Abstract 2292: Lung function and lung cancer risk: a Mendelian randomization study of UK Biobank cohort and the International Lung Cancer Consortium

Linda Kachuri, Mattias Johansson, Paul Brennan, Phillip Haycock, Geoffrey Liu, Maria Teresa Landi, David C. Christiani, Neil E. Caporaso, Xifeng Wu, Melinda C. Aldrich, Demetrius Albanes, Adonina Tardón, Gad Rennert, Chu Chen, Gary E. Goodman, Jennifer A. Doherty, Heike Bickeböller, Dawn Teare, Lambertus A. Kiemeney, Stig E. Bojesen, John K. Field, Aage Haugen, Stephen Lam, Loic Le Marchand, Matthew B. Schabath, Angeline S. Andrew, Jonas Manjer, Philip Lazarus, Susanne M. Arnold, Valérie Gaborieau, Richard Martin, Caroline Relton, George Davey Smith, Christopher I. Amos, James D. McKay, Rayjean J. Hung
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2292.
https://doi.org/10.1158/1538-7445.AM2017-2292
Published: 01 July 2017
View article titled, Abstract 2292: Lung function and lung cancer risk: a Mendelian randomization study of UK Biobank cohort and the International Lung Cancer Consortium
Journal Articles

Abstract 1241: A preclinical study of the combined treatment of arginase and canavanine in pancreatic cancer

Tsz Tung Kwong, Chi Hang Wong, Herbert Ho Fung Loong, Stephen Lam Chan
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1241.
https://doi.org/10.1158/1538-7445.AM2017-1241
Published: 01 July 2017
View article titled, Abstract 1241: A preclinical study of the combined treatment of arginase and canavanine in pancreatic cancer
Journal Articles

Abstract 5059: Preclinical study on the efficacy of Panobinostat in hepatocellular carcinoma

Chi Tung Choy, Wing Yu Man, Chi Hang Wong, Stephen Lam Chan
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5059.
https://doi.org/10.1158/1538-7445.AM2017-5059
Published: 01 July 2017
View article titled, Abstract 5059: Preclinical study on the efficacy of Panobinostat in hepatocellular carcinoma
Journal Articles

Abstract 817: Mendelian randomization and mediation analysis of 5p15.33, telomere length and lung cancer risk

Linda Kachuri, George Davey Smith, Geoffrey Liu, Maria Teresa Landi, David C. Christiani, Neil E. Caporaso, James D. McKay, Xifeng Wu, Melinda C. Aldrich, Gad Rennert, Dawn Teare, Chu Chen, Gary E. Goodman, Jennifer A. Doherty, John K. Field, Lambertus A. Kiemeney, Adonina Tardón, Aage Haugen, Stephen Lam, Loic Le Marchand, Matthew B. Schabath, Angeline S. Andrew, Mattias Johansson, Jonas Manjer, Philip Lazarus, Susanne Arnold, Gordon Fehringer, Xuchen Zong, Paul Brennan, Stig E. Bojesen, Christopher I. Amos, Rayjean J. Hung
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 817.
https://doi.org/10.1158/1538-7445.AM2016-817
Published: 15 July 2016
View article titled, Abstract 817: Mendelian randomization and mediation analysis of 5p15.33, telomere length and lung cancer risk
Journal Articles

Abstract 896: The airway field of injury reflects gene expression changes associated with the presence of lung squamous premalignant lesions

Sarah A. Mazzilli, Ania Tassinari, Yaron Gethalter, Gang Lui, Mary Pine, Stephen Lam, Mary Reid, Suso Platero, Marc Lenburg, Avrum Spira, Jennifer Beane
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 896.
https://doi.org/10.1158/1538-7445.AM2016-896
Published: 15 July 2016
View article titled, Abstract 896: The airway field of injury reflects gene expression changes associated with the presence of lung squamous premalignant lesions
Journal Articles

Abstract A21: MiR-106a and miR-106b affect growth and metastasis of lung adenocarcinoma

Katey SS Enfield, David A. Rowbotham, Alice Holly, Christine Anderson, Kevin W. Ng, Brenda de Carvalho Minatel, Graham Dellaire, Chiara Pastrello, Igor Jurisica, Calum MacAulay, Stephen Lam, Wan L. Lam
Journal: Cancer Research
Cancer Res (2016) 76 (6_Supplement): A21.
https://doi.org/10.1158/1538-7445.NONRNA15-A21
Published: 13 May 2016
View article titled, Abstract A21: MiR-106a and miR-106b affect growth and metastasis of lung adenocarcinoma
Journal Articles

Abstract B26: OIP5-Antisense 1, a long noncoding RNA deregulated in non-small cell lung cancer

Greg L. Stewart, Katey SS Enfield, David A. Rowbotham, Roland Hubaux, Victor Martinez, Stephen Lam, Wan Lam
Journal: Cancer Research
Cancer Res (2016) 76 (6_Supplement): B26.
https://doi.org/10.1158/1538-7445.NONRNA15-B26
Published: 13 May 2016
View article titled, Abstract B26: OIP5-Antisense 1, a long noncoding RNA deregulated in non-small cell lung cancer
Journal Articles

Abstract A2-63: Airway gene-coexpression network rewiring in the presence of bronchial dysplasia and lung cancer

Anna Tassinari, Bin Zhang, Katrina Steiling, Duncan Whitney, Kate Porta, Stephen Lam, Marc Lenburg, Avrum Spira, Jennifer Beane
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_1): A2-63.
https://doi.org/10.1158/1538-7445.TRANSCAGEN-A2-63
Published: 15 November 2015
View article titled, Abstract A2-63: Airway gene-coexpression network rewiring in the presence of bronchial dysplasia and lung cancer
Journal Articles

Abstract B1-17: Airway gene-coexpression network rewiring in the presence of bronchial dysplasia and lung cancer

Anna Tassinari, Bin Zhang, Katrina Steiling, Duncan Whitney, Kate Porta, Stephen Lam, Marc Lenburg, Avrum Spira, Jennifer Beane
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_2): B1-17.
https://doi.org/10.1158/1538-7445.COMPSYSBIO-B1-17
Published: 15 November 2015
View article titled, Abstract B1-17: Airway gene-coexpression network rewiring in the presence of bronchial dysplasia and lung cancer