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Abstract 3726: Physical activity levels are associated with transcriptomic pathways in colon tumors and tumor-adjacent visceral adipose tissue: Results from the ColoCare Study

Cancer Res (2025) 85 (8_Supplement_1): 3726.

https://doi.org/10.1158/1538-7445.AM2025-3726

Published: 21 April 2025

View articletitled, Abstract 3726: Physical activity levels are associated with transcriptomic pathways in colon tumors and tumor-adjacent visceral adipose tissue: Results from the ColoCare Study

Journal Articles

Abstract 7349: Ligand-receptor signaling analysis and tumor-immune microenvironment deconvolution reveal differential adipose-tumor crosstalk in lean and obese colon cancer patients

Cancer Res (2024) 84 (6_Supplement): 7349.

https://doi.org/10.1158/1538-7445.AM2024-7349

Published: 22 March 2024

View articletitled, Abstract 7349: Ligand-receptor signaling analysis and tumor-immune microenvironment deconvolution reveal differential adipose-tumor crosstalk in lean and obese colon cancer patients

Journal Articles

Abstract 1790: Pyruvate carboxylase regulates tumor progression through central carbon metabolism and immunosuppression

Michael F. Coleman, Eylem Kulkoyluoglu Cotul, Alexander J. Pfeil, Alyssa N. Ho, Emily N. Devericks, Muhammad H. Safdar, Hao Chen, Numair Attaar, Violet A. Kiesel, Dorothy Teegarden, Stephen D. Hursting, Michael K. Wendt

Cancer Res (2024) 84 (6_Supplement): 1790.

https://doi.org/10.1158/1538-7445.AM2024-1790

Published: 22 March 2024

View articletitled, Abstract 1790: Pyruvate carboxylase regulates tumor progression through central carbon metabolism and immunosuppression

Journal Articles

Abstract 365: Proteomic analysis of cytoplasmic lipid droplets and whole cell lysates reveal ferroptosis regulation by fatty acid synthase-derived lipid droplets in metastatic breast cancer

Chaylen Andolino, Kimberly K. Buhman, Michael F. Coleman, Stephen D. Hursting, Marjorie Layosa, Michael K. Wendt, Dorothy Teegarden

Cancer Res (2024) 84 (6_Supplement): 365.

https://doi.org/10.1158/1538-7445.AM2024-365

Published: 22 March 2024

View articletitled, Abstract 365: Proteomic analysis of cytoplasmic lipid droplets and whole cell lysates reveal ferroptosis regulation by fatty acid synthase-derived lipid droplets in metastatic breast cancer

Journal Articles

Abstract 2190: Transcriptomic signatures of obesity-driven colon cancer: A multi-species transdisciplinary approach

Cancer Res (2024) 84 (6_Supplement): 2190.

https://doi.org/10.1158/1538-7445.AM2024-2190

Published: 22 March 2024

View articletitled, Abstract 2190: Transcriptomic signatures of obesity-driven colon cancer: A multi-species transdisciplinary approach

Journal Articles

Abstract 2189: Tirzepatide mitigates obesity-associated metabolic dysregulation and tumor progression in a mouse model of triple-negative breast cancer

Elaine M. Glenny, Alyssa N. Ho, Violet A. Kiesel, Fangxin Chen, Claire E. Gates, Evan M. Paules, Ruihan Xu, C. Alex Holt, Michael F. Coleman, Stephen D. Hursting

Cancer Res (2024) 84 (6_Supplement): 2189.

https://doi.org/10.1158/1538-7445.AM2024-2189

Published: 22 March 2024

View articletitled, Abstract 2189: Tirzepatide mitigates obesity-associated metabolic dysregulation and tumor progression in a mouse model of triple-negative breast cancer

Journal Articles

Abstract 2188: Tirzepatide treatment restores antitumor immunity in a model of obesity-driven cancer

Michael F. Coleman, Elaine M. Glenny, Tori L. McFarlane, Hannah M. Malian, Claire E. Gates, Fangxin Chen, Alyssa N. Ho, Violet A. Kiesel, Stephen D. Hursting

Cancer Res (2024) 84 (6_Supplement): 2188.

https://doi.org/10.1158/1538-7445.AM2024-2188

Published: 22 March 2024

View articletitled, Abstract 2188: Tirzepatide treatment restores antitumor immunity in a model of obesity-driven cancer

Journal Articles

Abstract 2168: Intermittent fasting in combination with carboplatin in a pre-clinical model of obesity-driven endometrial cancer

Jennifer Haag, Olivia Lara, Chunxiao Zhou, Stephen D. Hursting, Victoria Bae-Jump

Cancer Res (2024) 84 (6_Supplement): 2168.

https://doi.org/10.1158/1538-7445.AM2024-2168

Published: 22 March 2024

View articletitled, Abstract 2168: Intermittent fasting in combination with carboplatin in a pre-clinical model of obesity-driven endometrial cancer

Journal Articles

Abstract 5259: Bazedoxifene plus conjugated estrogen improves metabolic health and reduces mammary gland epithelial proliferation in an ovary intact rat model of obesity and breast cancer risk

Ramsey M. Jenschke, Karen A. Corleto, Carol J. Fabian, Stephen D. Hursting, Bruce F. Kimler, Danilo Landrock, Tara N. Mahmood, Katherine L. Cook, Erin D. Giles

Cancer Res (2023) 83 (7_Supplement): 5259.

https://doi.org/10.1158/1538-7445.AM2023-5259

Published: 04 April 2023

View articletitled, Abstract 5259: Bazedoxifene plus conjugated estrogen improves metabolic health and reduces mammary gland epithelial proliferation in an ovary intact rat model of obesity and breast cancer risk

Journal Articles

Abstract 3030: Effect of 6 months of bazedoxifene and conjugated estrogen on measures of insulin resistance in postmenopausal women at increased risk for breast cancer

Carol J. Fabian, Erin D. Giles, Katherine L. Cook, Kandy Powers, Christy Altman, Amy Kreutzjans, Teresa Phillips, Adrian Zelenchuk, Krystal Pittman, Stephen D. Hursting, Bruce Kimler

Cancer Res (2023) 83 (7_Supplement): 3030.

https://doi.org/10.1158/1538-7445.AM2023-3030

Published: 04 April 2023

View articletitled, Abstract 3030: Effect of 6 months of bazedoxifene and conjugated estrogen on measures of insulin resistance in postmenopausal women at increased risk for breast cancer

Journal Articles

Abstract 1267: Suppression of pyruvate carboxylase drives PDL1 expression in mouse models of TNBC

Numair Attaar, Alexander J. Pfeil, Eylem K. Cotul, Dorothy Teegarden, Michael K. Wendt, Michael F. Coleman, Stephen D. Hursting

Cancer Res (2023) 83 (7_Supplement): 1267.

https://doi.org/10.1158/1538-7445.AM2023-1267

Published: 04 April 2023

View articletitled, Abstract 1267: Suppression of pyruvate carboxylase drives PDL1 expression in mouse models of TNBC

Journal Articles

Abstract 4235: Obesity drives inflammation and metabolic reprogramming in an orthotopic mouse model of early colon cancer

Elaine M. Glenny, Babak Mirminachi, Tori L. McFarlane, Jatin Roper, Stephen D. Hursting

Cancer Res (2023) 83 (7_Supplement): 4235.

https://doi.org/10.1158/1538-7445.AM2023-4235

Published: 04 April 2023

View articletitled, Abstract 4235: Obesity drives inflammation and metabolic reprogramming in an orthotopic mouse model of early colon cancer

Journal Articles

Abstract 656: Suppression of pyruvate carboxylase drives tumor microenvironment immunosuppression

Michael F. Coleman, Eylem Kulkoyluoglu Cotul, Alexander J. Pfeil, Emily N. Devericks, Muhammad H. Safdar, Hao Chen, Violet A. Kiesel, Dorothy Teegarden, Stephen D. Hursting, Michael K. Wendt

Cancer Res (2023) 83 (7_Supplement): 656.

https://doi.org/10.1158/1538-7445.AM2023-656

Published: 04 April 2023

View articletitled, Abstract 656: Suppression of pyruvate carboxylase drives tumor microenvironment immunosuppression

Journal Articles

Abstract 1995: β-Hydroxy-β-methylbutyrate promotes immunotherapy response and pro-inflammatory macrophage polarization in a mouse model of pancreatic cancer

Michael F. Coleman, Kristyn A. Liu, Alexander J. Pfeil, Suhas K. Etigunta, Xiaohu Tang, Laura M. Lashinger, Zhengrong Cui, Stephen D. Hursting

Cancer Res (2022) 82 (12_Supplement): 1995.

https://doi.org/10.1158/1538-7445.AM2022-1995

Published: 15 June 2022

View articletitled, Abstract 1995: β-Hydroxy-β-methylbutyrate promotes immunotherapy response and pro-inflammatory macrophage polarization in a mouse model of pancreatic cancer

Journal Articles

Abstract 1321: Effects of sulindac on inflammatory and cellular responses in mammary tumors from obese mice

Morgan E. Cody, Shannon B. McDonell, Qing Shi, Elaine M. Glenny, Michael F. Coleman, Stephen D. Hursting

Cancer Res (2022) 82 (12_Supplement): 1321.

https://doi.org/10.1158/1538-7445.AM2022-1321

Published: 15 June 2022

View articletitled, Abstract 1321: Effects of sulindac on inflammatory and cellular responses in mammary tumors from obese mice

Journal Articles

Abstract 3507: β-Hydroxy-β-methylbutyrate (HMB) sensitizes murine pancreatic ductal adenocarcinoma (PDAC) to immunotherapy

Suhas K. Etigunta, Michael F. Coleman, Kristyn A. Liu, Alex J. Pfeil, Zhengrong Cui, Stephen D. Hursting

Cancer Res (2022) 82 (12_Supplement): 3507.

https://doi.org/10.1158/1538-7445.AM2022-3507

Published: 15 June 2022

View articletitled, Abstract 3507: β-Hydroxy-β-methylbutyrate (HMB) sensitizes murine pancreatic ductal adenocarcinoma (PDAC) to immunotherapy

Journal Articles

Abstract 1336: Characterization of a novel transplantable model of obesity-driven basal-like breast cancer

Meredith S. Carson, Elaine M. Glenny, Violet A. Kiesel, Ashlee Taylor, Daniel Roth, Jody Albright, Melissa VerHague, John E. French, Michael F. Coleman, Stephen D. Hursting

Cancer Res (2022) 82 (12_Supplement): 1336.

https://doi.org/10.1158/1538-7445.AM2022-1336

Published: 15 June 2022

View articletitled, Abstract 1336: Characterization of a novel transplantable model of obesity-driven basal-like breast cancer

Journal Articles

Abstract 2388: Role of the primary cilium in the crosstalk between obesity and cancer

Ximena Bustamante-Marin, Jenna L. Merlino, Emma J. Grindstaff, Michael F. Coleman, Erika Rezeli, Kristina K. Camp, Laura Smith, Stephen D. Hursting

Cancer Res (2022) 82 (12_Supplement): 2388.

https://doi.org/10.1158/1538-7445.AM2022-2388

Published: 15 June 2022

View articletitled, Abstract 2388: Role of the primary cilium in the crosstalk between obesity and cancer

Journal Articles

Abstract 2376: Pyruvate carboxylase regulates mammary tumor microenvironment composition via central carbon metabolism

Alexander J. Pfeil, Michael F. Coleman, Eylem Kulkoyluoglu-Cotul, Violet Kiesel, Emily Devericks, Suhas K. Etigunta, Dorothy Teegarden, Michael K. Wendt, Stephen D. Hursting

Cancer Res (2022) 82 (12_Supplement): 2376.

https://doi.org/10.1158/1538-7445.AM2022-2376

Published: 15 June 2022

View articletitled, Abstract 2376: Pyruvate carboxylase regulates mammary tumor microenvironment composition via central carbon metabolism

Journal Articles

Abstract 612: Microbial determinants of immune checkpoint inhibition response in a murine model of obesity and metastatic basal-like breast cancer

Tori L. McFarlane, Meredith S. Carson, Elaine M. Glenny, Violet A. Kiesel, Ashlee Taylor, Daniel Roth, Jody Albright, Melissa VerHague, John E. French, Michael F. Coleman, Stephen D. Hursting

Cancer Res (2022) 82 (12_Supplement): 612.

https://doi.org/10.1158/1538-7445.AM2022-612

Published: 15 June 2022

View articletitled, Abstract 612: Microbial determinants of immune checkpoint inhibition response in a murine model of obesity and metastatic basal-like breast cancer

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Abstract 3726: Physical activity levels are associated with transcriptomic pathways in colon tumors and tumor-adjacent visceral adipose tissue: Results from the ColoCare Study

Abstract 7349: Ligand-receptor signaling analysis and tumor-immune microenvironment deconvolution reveal differential adipose-tumor crosstalk in lean and obese colon cancer patients

Abstract 1790: Pyruvate carboxylase regulates tumor progression through central carbon metabolism and immunosuppression

Abstract 365: Proteomic analysis of cytoplasmic lipid droplets and whole cell lysates reveal ferroptosis regulation by fatty acid synthase-derived lipid droplets in metastatic breast cancer

Abstract 2190: Transcriptomic signatures of obesity-driven colon cancer: A multi-species transdisciplinary approach

Abstract 2189: Tirzepatide mitigates obesity-associated metabolic dysregulation and tumor progression in a mouse model of triple-negative breast cancer

Abstract 2188: Tirzepatide treatment restores antitumor immunity in a model of obesity-driven cancer

Abstract 2168: Intermittent fasting in combination with carboplatin in a pre-clinical model of obesity-driven endometrial cancer

Abstract 5259: Bazedoxifene plus conjugated estrogen improves metabolic health and reduces mammary gland epithelial proliferation in an ovary intact rat model of obesity and breast cancer risk

Abstract 3030: Effect of 6 months of bazedoxifene and conjugated estrogen on measures of insulin resistance in postmenopausal women at increased risk for breast cancer

Abstract 1267: Suppression of pyruvate carboxylase drives PDL1 expression in mouse models of TNBC

Abstract 4235: Obesity drives inflammation and metabolic reprogramming in an orthotopic mouse model of early colon cancer

Abstract 656: Suppression of pyruvate carboxylase drives tumor microenvironment immunosuppression

Abstract 1995: β-Hydroxy-β-methylbutyrate promotes immunotherapy response and pro-inflammatory macrophage polarization in a mouse model of pancreatic cancer

Abstract 1321: Effects of sulindac on inflammatory and cellular responses in mammary tumors from obese mice

Abstract 3507: β-Hydroxy-β-methylbutyrate (HMB) sensitizes murine pancreatic ductal adenocarcinoma (PDAC) to immunotherapy

Abstract 1336: Characterization of a novel transplantable model of obesity-driven basal-like breast cancer

Abstract 2388: Role of the primary cilium in the crosstalk between obesity and cancer

Abstract 2376: Pyruvate carboxylase regulates mammary tumor microenvironment composition via central carbon metabolism

Abstract 612: Microbial determinants of immune checkpoint inhibition response in a murine model of obesity and metastatic basal-like breast cancer

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