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Journal Articles

Abstract 7361: Scientific rationale and successful implementation of biospecimen collection in the NCI Connect Cohort for Cancer Prevention

Free
Nicolas A. Wentzensen, Stephanie Weinstein, Amanda Black, Erin Schwartz, Hannah P. Yang, Michelle Brotzman, Paul Albert, Laura Beane-Freeman, Amy Berrington, Jonas De Almeida, Jonine D. Figueroa, Montserrat Garcia-Closas, Nicole Gerlanc, Gretchen Gierach, Rena Jones, Peter Kraft, Charles Matthews, Habib Ahsan, Brisa Aschebrook-Kilfoy, Chun-Hung Chan, Robert Greenlee, Stacey Honda, Ben Rybicki, Blythe Ryerson, Katherine Sanchez, Mark Schmidt, Kevin Sykes, Larissa White, Jeanette Ziegenfuss, Stephen Chanock, Christian Abnet, Mia Gaudet
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 7361.
https://doi.org/10.1158/1538-7445.AM2025-7361
Published: 21 April 2025
View articletitled, Abstract 7361: Scientific rationale and successful implementation of biospecimen collection in the NCI Connect Cohort for Cancer Prevention
Journal Articles

Abstract 6154: Targeted CRISPRi screen identifies functional variants and novel target genes at multiple renal cell carcinoma (RCC) susceptibility loci

Free
Timothy Winter, Timothy Myers, Leandro Colli, Lea Jessop, Jiyeon Choi, Mitchell J. Machiela, Mark P. Purdue, Kevin Brown, Stephen Chanock
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6154.
https://doi.org/10.1158/1538-7445.AM2024-6154
Published: 22 March 2024
View articletitled, Abstract 6154: Targeted CRISPRi screen identifies functional variants and novel target genes at multiple renal cell carcinoma (RCC) susceptibility loci
Journal Articles

Abstract 1710: DPF3 over-expression oncogenic effect in renal cancer is through SWI/SNF BAF complex

Free
Leticia Andrade Costa, Aline Gomes Souza, Vírginia Campos Silvestrini, Timothy Myers, Vitor Marcel Faça, Stephen Chanock, Leandro Machado Colli
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1710.
https://doi.org/10.1158/1538-7445.AM2024-1710
Published: 22 March 2024
View articletitled, Abstract 1710: DPF3 over-expression oncogenic effect in renal cancer is through SWI/SNF BAF complex
Journal Articles

Abstract 1762: Characterization of somatic copy number deletion of chromosome 22q in papillary thyroid carcinoma

Free
Olivia W. Lee, Danielle Karyadi, Stephen Hartley, Weyin Zhou, Mitchell Machiela, Mykola Tronko, Tetiana Bogdanova, Liudmyla Zurnadzhy, Lindsay Morton, Stephen Chanock
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1762.
https://doi.org/10.1158/1538-7445.AM2024-1762
Published: 22 March 2024
View articletitled, Abstract 1762: Characterization of somatic copy number deletion of chromosome 22q in papillary thyroid carcinoma
Journal Articles

Abstract 5241: Association of polygenic risk scores with breast cancer risk among women with benign breast disease

Free
Stacey J. Winham, Mark Sherman, Robert Vierkant, Bryan McCauley, Christopher Scott, Mia Gaudet, Melissa Troester, Sandhya Pruthi, Derek Radisky, Amy Degnim, Kristan Aronson, Rachel Murphy, Pascal Guenel, Therese Truong, Jenny Chang-Claude, Heiko Becher, Montserrat Garcia-Closas, Stephen Chanock, Thomas Ahearn, Xiaohong Yang, Doug Easton, Manjeet Bolla, Celine Vachon, Breast Cancer Association Consortium
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5241.
https://doi.org/10.1158/1538-7445.AM2023-5241
Published: 04 April 2023
View articletitled, Abstract 5241: Association of polygenic risk scores with breast cancer risk among women with benign breast disease
Journal Articles

Abstract 688: Multi-stage exome sequencing study of 17,546 aggressive and non-aggressive prostate cancer cases

Free
Burcu F. Darst, Ed Saunders, Tokhir Dadaev, Xin Sheng, Peggy Wan, Loreall Pooler, Lucy Y. Xia, Stephen Chanock, Sonja I. Berndt, Susan M. Gapstur, Victoria Stevens, Demetrius Albanes, Stephanie J. Weinstein, Vincent Gnanapragasam, Graham G. Giles, Tu Nguyen-Dumont, Roger L. Milne, Mark M. Pomerantz, Julie A. Schmidt, Ruth C. Travis, Timothy J. Key, Konrad H. Stopsack, Lorelei A. Mucci, William J. Catalona, Beth Marosy, Kurt N. Hetrick, Kimberly F. Doheny, Robert J. MacInnis, Melissa C. Southey, Rosalind A. Eeles, Fredrik Wiklund, Zsofia Kote-Jarai, David V. Conti, Christopher A. Haiman
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 688.
https://doi.org/10.1158/1538-7445.AM2022-688
Published: 15 June 2022
View articletitled, Abstract 688: Multi-stage exome sequencing study of 17,546 aggressive and non-aggressive prostate cancer cases
Journal Articles

Abstract 3436: Pan-cancer analysis of the HIF-transcriptional pathway and its association with genetic susceptibility to cancer

Free
David R. Mole, Virginia Schmid, Olivia Lombardi, Silvia Halim, Veronique N. Lafleur, Ran Li, Rafik Salama, Leandro Colli, Stephen Chanock, Peter J. Ratcliffe
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3436.
https://doi.org/10.1158/1538-7445.AM2020-3436
Published: 15 August 2020
View articletitled, Abstract 3436: Pan-cancer analysis of the HIF-transcriptional pathway and its association with genetic susceptibility to cancer
Journal Articles

Abstract SY26-02: Sherlock-Lung: Tracing lung cancer mutational processes in never smokers

Free
Maria Teresa Landi, Tongwu Zhang, Montserrat Garcia-Closas, Yohan Bossé, Jianxin Shi, Bin Zhu, Qing Lan, Nathaniel Rothman, Jiyeon Choi, Neil E. Caporaso, Wei Zhao, Chongyi Chen, Eytan Ruppin, Jennifer Rosenbaum, Dmitry Gordenin, Sai Yendamuri, Chris Amos, Paul Brennan, David C. Christiani, Geoff Liu, Bonnie Gould Rothberg, Matthew Schabath, Han Liang, Ludmil Alexandrov, David Wedge, Stephen Chanock
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): SY26-02.
https://doi.org/10.1158/1538-7445.AM2019-SY26-02
Published: 01 July 2019
View articletitled, Abstract SY26-02: Sherlock-Lung: Tracing lung cancer mutational processes in never smokers
Journal Articles

Abstract 2682: Analysis of polygenic risk score interaction with coal use and risk of lung adenocarcinoma among never-smoking women in Asia

Free
Batel Blechter, Chao Agnes Hsiung, Zhihua Yin, Xiao-Ou Shu, H. Dean Hosgood, Jason Y.Y Wong, Jianxin Shi, Wei Hu, Bryan Bassig, Wei Jie Seow, Yu -ang Gao, Qiuyin Cai, Yong-Bing Xiang, I-Shou Chang, Baosen Zhou, Wei Zheng, Kyoung-Mu Lee, Stephen Chanock, Nilanjan Chatterjee, Nathaniel Rothman, Qing Lan
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2682.
https://doi.org/10.1158/1538-7445.AM2019-2682
Published: 01 July 2019
View articletitled, Abstract 2682: Analysis of polygenic risk score interaction with coal use and risk of lung adenocarcinoma among never-smoking women in Asia
Journal Articles

Abstract A13: Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility

Free
Mitchell J. Machiela, Thomas G.P. Grünewald, Didier Surdez, Stephanie Reynaud, Olivier Mirabeau, Eric Karlins, Rebeca Alba Rubio, Sakina Zaidi, Sandrine Grossetete-Lalami, Stelly Ballet, Eve Lapouble, Valérie Laurence, Jean Michon, Gaelle Pierron, Heinrich Kovar, Nathalie Gaspar, Udo Kontny, Anna González-Neira, Piero Picci, Javier Alonso, Ana Patino-Garcia, Nadège Corradini, Neal D. Freedman, Nathaniel Rothman, Casey L. Dagnall, Laurie Burdett, Kristine Jones, Michelle Manning, Kathleen Wyatt, Weiyin Zhou, Meredith Yeager, David G. Cox, Robert N. Hoover, Javed Khan, Gregory T. Armstrong, Wendy M. Leisenring, Smita Bhatia, Leslie L. Robison, Uta Dirksen, Markus Metzler, Wolfgang Hartmann, Konstantin Strauch, Thomas Kirchner, Andreas E. Kulozik, Lindsay M. Morton, Lisa Mirabello, Margaret A. Tucker, Franck Tirode, Stephen Chanock, Olivier Delattre
Journal: Cancer Research
Cancer Res (2018) 78 (19_Supplement): A13.
https://doi.org/10.1158/1538-7445.PEDCA17-A13
Published: 01 October 2018
View articletitled, Abstract A13: Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility
Journal Articles

Abstract 1187: Comparison of intra-tumor heterogeneity and clonal evolution across lung cancer subtypes by multi-region whole genome sequencing

Free
Tongwu Zhang, Joshua Sampson, Pier Alberto Bertazzi, Angela Pesatori, Dario Consonni, Bin Zhu, Belynda Hicks, Xing Hua, Jianxin Shi, Kevin Brown, Stephen Chanock, Maria Teresa Landi
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1187.
https://doi.org/10.1158/1538-7445.AM2018-1187
Published: 01 July 2018
View articletitled, Abstract 1187: Comparison of intra-tumor heterogeneity and clonal evolution across lung cancer subtypes by multi-region whole genome sequencing
Journal Articles

Abstract 227: Germline variation at 8q24 and prostate cancer risk in men of European ancestry

Free
Marco Matejcic, Edward J. Saunders, Tokhir Dadaev, Mark Brook, Ali Amin Al Olama, Fredrick R. Schumacher, Sonja I. Berndt, Sara Benlloch, Kenneth Muir, Koveela Govindasami, Victoria L. Stevens, Susan M. Gapstur, Catherine M. Tangen, Jyotsna Batra, Judith Clements, APCB (Australian Prostate Cancer Bio Resource), Henrik Gronberg, Nora Pashayan, Johanna Schleutker, Demetrius Albanes, Alicja Wolk, Catharine West, Lorelei Mucci, Peter Kraft, Géraldine Cancel-Tassin, Stella Koutros, Karina Dalsgaard Sorensen, Lovise Maehle, Eli Marie Grindedal, Sara Strom, David E. Neal, Freddie C. Hamdy, Jenny L. Donovan, Ruth C. Travis, Robert J. Hamilton, Sue Ann Ingles, Barry Rosenstein, Yong-Jie Lu, Graham G. Giles, Adam S. Kibel, Ana Vega, Jeanette Bensen, Manolis Kogevinas, Fredrik Wiklund, Stephen Chanock, Douglas F. Easton, Rosalind A. Eeles, Zsofia Kote-Jarai, David V. Conti, Christopher A. Haiman
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 227.
https://doi.org/10.1158/1538-7445.AM2018-227
Published: 01 July 2018
View articletitled, Abstract 227: Germline variation at 8q24 and prostate cancer risk in men of European ancestry
Journal Articles

Abstract 2185: Multiple region whole-genome sequencing reveals intratumor heterogeneity and branching clonal architecture of non-clear-cell renal cell carcinoma

Free
Bin Zhu*, Luana Poeta*, Manuela Costantini*, Tongwu Zhang*, Steno Sentinelli, Jianxin Shi, Kevin Brown, Xing Hua, Meredith Yeager, Mingyi Wang, Belynda Hicks, Stephen Chanock*, Michele Gallucci*, Vito Fazio*, Maria Teresa Landi*
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2185.
https://doi.org/10.1158/1538-7445.AM2018-2185
Published: 01 July 2018
View articletitled, Abstract 2185: Multiple region whole-genome sequencing reveals intratumor heterogeneity and branching clonal architecture of non-clear-cell renal cell carcinoma
Journal Articles

Abstract 3273: rkmh: A MinHash toolbox for analyzing HPV coinfections

Free
Eric T. Dawson, Sarah Wagner, David Roberson, Meredith Yeager, Joseph Boland, Erik Garrison, Mark Schiffman, Tina Raine-Bennet, Thomas Lorey, Phillip Castle, Stephen Chanock, Lisa Mirabello, Richard Durbin
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3273.
https://doi.org/10.1158/1538-7445.AM2018-3273
Published: 01 July 2018
View articletitled, Abstract 3273: rkmh: A MinHash toolbox for analyzing HPV coinfections
Journal Articles

Abstract 3369: Mosaic chromosome X copy-number aberrations in leukocytes of never-smoking lung cancer patients: The Female Lung Cancer Consortium in Asia (FLCCA)

Free
Jason Y. Wong, Mitchell Machiela, Weiyin Zhou, Wei Jie Seow, Bryan Bassig, Jinming Zhang, Meredith Yeager, Wei Zheng, Xiao-Ou Shu, Hongbing Shen, Keitaro Matsuo, Chao Agnes Hsiung, Maria P. Wong, Yun-Chul Hong, Jiu-cun Wang, Yi-Long Wu, Baosen Zhou, Robert Klein, Zhihua Yin, Tangchun Wu, Pan-Chyr Yang, Yong-Bing Xiang, Adeline Seow, Yu-Tang Gao, Chen Wu, Jianjun Liu, Zhibin Hu, Laurie Burdett, Qiuyin Cai, Juncheng Dai, Dongxin Lin, Kexin Chen, Stephen Chanock, Nathaniel Rothman, Qing Lan
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3369.
https://doi.org/10.1158/1538-7445.AM2018-3369
Published: 01 July 2018
View articletitled, Abstract 3369: Mosaic chromosome X copy-number aberrations in leukocytes of never-smoking lung cancer patients: The Female Lung Cancer Consortium in Asia (FLCCA)
Journal Articles

Abstract 242: Large pathway and gene set analysis of GWAS data identifies novel associations for pancreatic cancer

Free
Naomi Walsh, Han Zhang, Paula L. Hyland, Qi Yang, Evelina Mocci, Mingfeng Zhang, Erica J. Childs, Zhaoming Wang, Stephen Chanock, Patricia Hartge, Robert Hoover, Peter Kraft, Donghui Li, Eric J. Jacobs, Gloria M. Petersen, Brian M. Wolpin, Harvey A. Risch, Laufey T. Amundadottir, Kai Yu, Alison P. Klein, Rachael Z. Stolzenberg-Solomon
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 242.
https://doi.org/10.1158/1538-7445.AM2018-242
Published: 01 July 2018
View articletitled, Abstract 242: Large pathway and gene set analysis of GWAS data identifies novel associations for pancreatic cancer
Journal Articles

Abstract 228: Association analysis across different populations identifies 26 new cutaneous melanoma risk loci

Free
Cristina Pellegrini, Matthew Law, Mark Iles, Mitch Machiela, Alex Stratigos, Tongwu Zhang, Kevin Brown, Julia Newton-Bishop, Nick Hayward, Nick Martin, Alisa Goldstein, Rose Yang, Stephen Chanock, Florence Demenais, Susana Puig, Eduardo Nagore, Jianxin Shi, Tim Bishop, Stuart McGregor, Maria Teresa Landi, GenoMEL Consortium, MelaNostrum Consortium
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 228.
https://doi.org/10.1158/1538-7445.AM2018-228
Published: 01 July 2018
View articletitled, Abstract 228: Association analysis across different populations identifies 26 new cutaneous melanoma risk loci
Journal Articles

Abstract 223: A meta-analysis of genome-wide association studies of multiple myeloma among African Americans

Free
Zhaohui Du, Chi Song, Kristin Rand, Niels Weinhold, David Van Den Berg, Amie Hwang, Xin Sheng, Victor Hom, Sikander Ailawadhi, Ajay K. Nooka, Seema Singhal, Karen Pawlish, Edward S. Peters, Cathryn Bock, Ann Mohrbacher, Alexander Stram, Sonja I. Berndt, William Blot, John David Carpten, Antoinette Stroup, Andrew Olshan, Wei Zhang, African Ancestry Breast & Prostate Consortium, Stephen Chanock, Jayesh Mehta, Graham A. Colditz, Jeffrey Wolf, Thomas G. Martin, Michael Tomasson, Mark A. Fiala, Howard Terebelo, Nalini Janakiraman, Laurence Kolonel, Loic LeMarchand, Elad Ziv, Daniel Stram, Ravi Vij, Leon Bernal-Mizrachi, Gareth J. Morgan, Jeffrey A. Zonder, Carol Ann Huff, Sagar Lonial, Robert Z. Orlowski, David V. Conti, Christopher A. Haiman, Wendy Cozen
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 223.
https://doi.org/10.1158/1538-7445.AM2018-223
Published: 01 July 2018
View articletitled, Abstract 223: A meta-analysis of genome-wide association studies of multiple myeloma among African Americans
Journal Articles

Abstract 4871: Whole-exome sequencing identifies a high frequency of germline deleterious variants in cancer predisposition genes in individuals with osteosarcoma

Free
Roelof Koster, Bin Zhu, Meredith Yeager, Michael Dean, Matthew Gianferante, Lei Song, Joshua Sampson, NCI DCEG Cancer Genomics Research Laboratory, Julie Gastier-Foster, Richard Gorlick, Silvia Regina Caminada de Toledo, Antonio Petrilli, Ana Patiño-Garcia, Fernando Lecanda, Massimo Serra, Claudia Hattinger, Piero Picci, Katia Scotlandi, Adrienne Flanagan, Roberto Tirabosco, Maria Amary, Nilgün Kurucu, Inci Ergurhan Ilhan, Neriman Sari, Mandy Ballinger, David Thomas, Donald Barkauskas, Belynda Hicks, Margaret Tucker, Neil Caporaso, Robert Hoover, Stephen Chanock, Sharon Savage, Lisa Mirabello
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4871.
https://doi.org/10.1158/1538-7445.AM2017-4871
Published: 01 July 2017
View articletitled, Abstract 4871: Whole-exome sequencing identifies a high frequency of germline deleterious variants in cancer predisposition genes in individuals with osteosarcoma
Journal Articles

Abstract 1302: Genome-wide association study of glioma reveals specific differences in genetic susceptibility to glioblastoma and non-glioblastoma

Free
Ben Kinnersley, Beatrice S. Melin, Jill S. Barnholtz-Sloan, Margaret R. Wrensch, Christoffer Johansen, Dora Il’yasova, Quinn Ostrom, and members of GICC, Karim Labreche, Jeanette E. Eckel-Passow, Paul A. Decker, Marianne Labussière, Ahmed Idbaih, Khe Hoang-Xuan, Anna-Luisa Di Stefano, Karima Mokhtari, Jean-Yves Delattre, Pilar Galan, Konstantinos Gousias, Johannes Schramm, Minouk J. Schoemaker, Sarah J. Fleming, Stefan Herms, Stefanie Heilmann, Marcus M. Nöthen, Heinz-Erich Wichmann, Stefan Schreiber, Anthony Swerdlow, Mark Lathrop, Matthias Simon, Marc Sanson, Preetha Rajaraman, Stephen Chanock, Martha Linet, Zhaoming Wang, Meredith Yeager, Rose K. Lai, Elizabeth B. Claus, Sara H. Olson, Robert B. Jenkins, Richard S. Houlston, Melissa L. Bondy
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1302.
https://doi.org/10.1158/1538-7445.AM2017-1302
Published: 01 July 2017
View articletitled, Abstract 1302: Genome-wide association study of glioma reveals specific differences in genetic susceptibility to glioblastoma and non-glioblastoma