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Stephen B Gruber
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Journal Articles

Abstract 5874: Heterozygote advantage at HLA class I and II loci and colorectal cancer risk

Ya-Yu Tsai, Chenxu Qu, Joseph D. Bonner, Rebeca Sanz-Pamplona, Sidney Lindsey, Marilena Melas, Kevin J. McDonnell, Gregory E. Idos, Christopher P. Walker, Kevin K. Tsang, Diane M. Da Silva, Ferran Moratalla, Asaf Maoz, Hedy S. Rennert, W. Martin Kast, Joel K. Greenson, Victor Moreno, Gad Rennert, Stephen B. Gruber, Stephanie L. Schmit
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5874.
DOI: https://doi.org/10.1158/1538-7445.AM2022-5874
Published: 15 June 2022
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Journal Articles

Abstract 2737: Clinical and epidemiologic predictors of clonal immune responses in colorectal cancer

Stephen B. Gruber, Joseph D. Bonner, Sidney S. Lindsey, Ya-Yu Tsai, Rebeca Sanz-Pamplona, M. Henar Alonso, Marilena Melas, Hedy S. Rennert, Kevin J. McDonnell, Gregory E. Idos, Christopher P. Walker, W. Martin Kast, Diane Da Silva, Harlan S. Robins, Joel K. Greenson, Victor Moreno, Stephanie L. Schmit, Gad Rennert
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2737.
DOI: https://doi.org/10.1158/1538-7445.AM2021-2737
Published: 01 July 2021
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Journal Articles

Abstract 835: T-cell abundance, clonality and disease specific survival in colorectal cancer

Joseph Bonner, Sephanie L. Schmit, Sidney S. Lindsey, Ya-Yu Tsai, Rebeca Sanz-Pamplona, M. Henar Alonso, Marilena Melas, Hedy S. Rennert, Kevin J. McDonnell, Gregory Idos, Christopher P. Walker, W. Martin Kast, Diane Da Silva, Harlan S. Robins, Joel K. Greenson, Victor Moreno, Gad Rennert, Stephen B. Gruber
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 835.
DOI: https://doi.org/10.1158/1538-7445.AM2021-835
Published: 01 July 2021
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Journal Articles

Abstract 824: Germline genetic regulation of the adaptive immune response in colorectal cancer

Stephanie L. Schmit, Ya-Yu Tsai, Joseph Bonner, Rebeca Sanz-Pamplona, Amit D. Joshi, Sidney S. Lindsey, Marilena Melas, Kevin J. McDonnell, Gregory E. Idos, Christopher P. Walker, W. Martin Kast, Diane Da Silva, Tomotaka Ugai, Hedy S. Rennert, Harlan S. Robins, Joel K. Greenson, Shuji Ogino, Victor Moreno, Gad Rennert, Stephen B. Gruber
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 824.
DOI: https://doi.org/10.1158/1538-7445.AM2021-824
Published: 01 July 2021
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Journal Articles

Abstract 819: Consumption of fruits, vegetables and fiber and risk of colorectal cancer: A gene environment interaction analysis

Nikos Papadimitriou, Akihisa Hidaka, Andre Kim, Niki Dimou, Neil Murphy, Sonja I. Berndt, David Conti, Peter T. Campbell, Graham Casey, Jane C. Figueiredo, Konstantinos K. Tsilidis, Stephen B. Gruber, Sophia Harlid, Yi Lin, Victor Moreno, Lori C. Sakoda, Virginia D. Obrero, Li Hsu, William J. Gauderman, Marc Gunter, Ulrike Peters
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 819.
DOI: https://doi.org/10.1158/1538-7445.AM2021-819
Published: 01 July 2021
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Journal Articles

Abstract 818: Association of polygenic risk score and menopausal hormone therapy for colorectal cancer risk

Yu Tian, Yi Lin, Andre E. Kim, Stephanie A. Bien, Polly A. Newcomb, Graham Casey, Elizabeth A. Platz, Loic Le Marchand, Peter T. Campbell, Hermann Brenner, Michael Hoffmeister, Feng Guo, Xuechen Chen, Marc J. Gunter, Niki Dimou, Stephen B. Gruber, Andrew T. Chan, Amit D. Joshi, Sonja I. Berndt, Emily White, Victor Moreno, Ross L. Prentice, Ulrike Peters, William Gauderman, Li Hsu, Jenny Chang-Claude
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 818.
DOI: https://doi.org/10.1158/1538-7445.AM2021-818
Published: 01 July 2021
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Journal Articles

Abstract 817: Probing the diabetes - colorectal cancer link using gene - environment interaction analyses

Niki Dimou, Andre E. Kim, Orlagh Flanagan, Neil Murphy, Emmanouil Bouras, Peter T. Campbell, Graham Casey, Steven Gallinger, Stephen B. Gruber, Li Hsu, Mark A. Jenkins, Yi Lin, Victor Moreno, Conghui Qu, Edward Ruiz-Narvaez, Mariana C. Stern, Yu Tian, Kostas Tsilidis, W. James Gauderman, Marc J. Gunter, Ulrike Peters
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 817.
DOI: https://doi.org/10.1158/1538-7445.AM2021-817
Published: 01 July 2021
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Journal Articles

Abstract 881: Benchmarking genome-wide polygenic risk score development techniques in colorectal cancer risk prediction

Minta Thomas, Lori C Sakoda, Jeffrey K Lee, Mark A Jenkins, Andrea Burnett-Hartman, Heather Hampel, Elisabeth A Rosenthal, Hermann Brenner, Jenny Chang-Claude, Marc J Gunter, Polly A Newcomb, Steven Gallinger, Tabitha A Harrison, Graham Casey, Victor Moreno, Gail P Jarvik, Stephen B Gruber, Robert E Schoen, Andrew T Chan, Richard B Hayes, Douglas A Corley, Ulrike Peters, Li Hsu
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 881.
DOI: https://doi.org/10.1158/1538-7445.AM2021-881
Published: 01 July 2021
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Journal Articles

Abstract 2332: Tumor infiltrating lymphocytes, immunoSeq, and CMS classification in the molecular epidemiology of colorectal cancer study

Marilena Melas, Charalampos Lazaris, Stephanie L. Schmit, Asaf Maoz, Rebeca Sanz Pamplona, Chenxu Qu, Joel K. Greenson, Rork Kuick, Flavio Lejbkowicz, Hedy S. Rennert, Christopher P. Walker, Chase M. Bowen, Diane M. Da Silva, W. Martin Kast, Gregory E. Idos, Kevin J. McDonnell, Victor Moreno, Gad Rennert, Stephen B. Gruber
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2332.
DOI: https://doi.org/10.1158/1538-7445.AM2019-2332
Published: 01 July 2019
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Journal Articles

Abstract 2685: Identification of circulating protein biomarkers for colorectal cancer risk: A genetic instrument analysis

Xiang Shu, Xiao-ou Shu, Jirong Long, Qiuyin Cai, Conghui Qu, Stephanie L. Schmit, Chenxu Qu, Sonja I. Berndt, Peter T. Campbell, Andrew T. Chan, Graham G. Giles, Andrea Gsur, Michael Hoffmeister, Mark A. Jenkins, Sanford D. Markowitz, Li Li, Gad Rennert, Kenneth Offit, David Conti, Annika Lindblom, Graham Casey, Stephen B. Gruber, Ulrike Peters, Wei Zheng
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2685.
DOI: https://doi.org/10.1158/1538-7445.AM2019-2685
Published: 01 July 2019
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Journal Articles

Abstract 4746: Microbes in the tumor microenvironment: Bacterial influences on host immunity in colorectal cancer

Christine M. Pierce, Bo-young Hong, Hannah J. Hoehn, Maria F. Gomez, Marilena Melas, Kevin McDonnell, Youngchul Kim, Erica Sodergren, George Weinstock, Hedy S. Rennert, Thomas Giordano, Joel Greenson, Gad Rennert, Stephen B. Gruber, Stephanie L. Schmit
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4746.
DOI: https://doi.org/10.1158/1538-7445.AM2018-4746
Published: 01 July 2018
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Journal Articles

Abstract 235: Type 2 diabetes and glycemic traits in relation to colorectal cancer risk: A Mendelian randomization study

Mingyang Song, Yiwen Lu, Marc Gunter, Neil Murphy, Barbara L. Banbury, Wenjie Ma, Jennifer Prescott, Graham Casey, Stephen B. Gruber, Edward L. Giovannucci, Ulrike Peters, Andrew T. Chan
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 235.
DOI: https://doi.org/10.1158/1538-7445.AM2018-235
Published: 01 July 2018
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Journal Articles

Abstract A17: Molecular and clinicopathological features of native Nigerian colorectal cancer

David O. Irabor, Marilena Melas, Stephen B. Gruber, Chanjuan Shi, Leon Raskin
Journal: Cancer Research
Cancer Res (2017) 77 (22_Supplement): A17.
DOI: https://doi.org/10.1158/1538-7445.NEWFRONT17-A17
Published: 14 November 2017
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Journal Articles

Cross-Cancer Analysis Reveals Novel Pleiotropic Associations—Response

Rayjean J. Hung, Gordon Fehringer, Graham Casey, Stephen B. Gruber, Ulrike Peters, Ellen L. Goode, Thomas A. Sellers, Christopher A. Haiman, David J. Hunter, Peter Kraft, Christopher I. Amos, Matthew L. Freedman, Michael D. Wilson
Journal: Cancer Research
Cancer Res (2017) 77 (21): 6045–6046.
DOI: https://doi.org/10.1158/0008-5472.CAN-17-1584
Published: 31 October 2017
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Journal Articles

Abstract 1304: The contribution of rare and low-frequency variants to colorectal cancer heritability

Jeroen R. Huyghe, Sai Chen, Hyun M. Kang, Tabitha Harrison, Sonja I. Berndt, Stephane Bézieau, Hermann Brenner, Graham Casey, Andrew T. Chan, Jenny Chang-Claude, Steven J. Gallinger, Stephen B. Gruber, Andrea Gsur, Michael Hoffmeister, Thomas Hudson, Mark A. Jenkins, Loic Le Marchand, Polly A. Newcomb, John D. Potter, Conghui Qu, Martha L. Slattery, Joshua D. Smith, Emily White, Goncalo R. Abecasis, Li Hsu, Deborah A. Nickerson, Ulrike Peters, on behalf of CCFR and GECCO
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1304.
DOI: https://doi.org/10.1158/1538-7445.AM2017-1304
Published: 01 July 2017
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Journal Articles

Abstract 1300: Genetic predictors of gene expression associated with risk of colorectal cancer

Stephanie A. Bien, Xingyi Guo, Yu-Ru Su, Tabitha A. Harrison, Conghui Qu, Yingchang Lu, Jiron Long, Sai Chen, Andrew T. Chan, David V. Conti, Hyun M. Kang, Michael Hoffmeister, Thomas J. Hudson, Mark A. Jenkins, Loic Le Marchand, Polly A. Newcomb, Martha L. Slattery, Emily White, Goncalo R. Abeçasis, Stephen B. Gruber, Deborah A. Nickerson, Stephanie L. Schmit, Graham Casey, Li Hsu, Wei Zheng, Ulrike Peters, GECCO-CCFR-AAAC-CORECT
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1300.
DOI: https://doi.org/10.1158/1538-7445.AM2017-1300
Published: 01 July 2017
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Journal Articles

Abstract LB-161: GAME-ON and OncoArray: Understanding the genetic architecture of cancer risk

Stefanie A. Nelson, Charlisse Caga-Anan, Danielle Daee, Maura Kate Costello, Daniela Seminara, Christopher I. Amos, Stephen B. Gruber, Christopher Haiman, David Hunter, Peter Kraft, Thomas Sellers, Elizabeth M. Gillanders
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-161.
DOI: https://doi.org/10.1158/1538-7445.AM2017-LB-161
Published: 01 July 2017
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Journal Articles

Abstract 491: Elucidating de novo PATRR-mediated t(3;8) balanced translocation and clear cell renal cell carcinoma

Marilena Melas, Kevin J. McDonnell, Christopher K. Edlund, Sarah J. Tash, Duveen Y. Sturgeon, Chenxu Qu, Charalampos Lazaris, Peter J. Gruber, Thomas W. Glover, Beverly S. Emanuel, Stephen B. Gruber
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 491.
DOI: https://doi.org/10.1158/1538-7445.AM2017-491
Published: 01 July 2017
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Journal Articles

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations

Gordon Fehringer, Peter Kraft, Paul D. Pharoah, Rosalind A. Eeles, Nilanjan Chatterjee, Fredrick R. Schumacher, Joellen M. Schildkraut, Sara Lindström, Paul Brennan, Heike Bickeböller, Richard S. Houlston, Maria Teresa Landi, Neil Caporaso, Angela Risch, Ali Amin Al Olama, Sonja I. Berndt, Edward L. Giovannucci, Henrik Grönberg, Zsofia Kote-Jarai, Jing Ma, Kenneth Muir, Meir J. Stampfer, Victoria L. Stevens, Fredrik Wiklund, Walter C. Willett, Ellen L. Goode, Jennifer B. Permuth, Harvey A. Risch, Brett M. Reid, Stephane Bezieau, Hermann Brenner, Andrew T. Chan, Jenny Chang-Claude, Thomas J. Hudson, Jonathan K. Kocarnik, Polly A. Newcomb, Robert E. Schoen, Martha L. Slattery, Emily White, Muriel A. Adank, Habibul Ahsan, Kristiina Aittomäki, Laura Baglietto, Carl Blomquist, Federico Canzian, Kamila Czene, Isabel dos-Santos-Silva, A. Heather Eliassen, Jonine D. Figueroa, Dieter Flesch-Janys, Olivia Fletcher, Montserrat Garcia-Closas, Mia M. Gaudet, Nichola Johnson, Per Hall, Aditi Hazra, Rebecca Hein, Albert Hofman, John L. Hopper, Astrid Irwanto, Mattias Johansson, Rudolf Kaaks, Muhammad G. Kibriya, Peter Lichtner, Jianjun Liu, Eiliv Lund, Enes Makalic, Alfons Meindl, Bertram Müller-Myhsok, Taru A. Muranen, Heli Nevanlinna, Petra H. Peeters, Julian Peto, Ross L. Prentice, Nazneen Rahman, Maria Jose Sanchez, Daniel F. Schmidt, Rita K. Schmutzler, Melissa C. Southey, Rulla Tamimi, Ruth C. Travis, Clare Turnbull, Andre G. Uitterlinden, Zhaoming Wang, Alice S. Whittemore, Xiaohong R. Yang, Wei Zheng, Daniel D. Buchanan, Graham Casey, David V. Conti, Christopher K. Edlund, Steven Gallinger, Robert W. Haile, Mark Jenkins, Loïc Le Marchand, Li Li, Noralene M. Lindor, Stephanie L. Schmit, Stephen N. Thibodeau, Michael O. Woods, Thorunn Rafnar, Julius Gudmundsson, Simon N. Stacey, Kari Stefansson, Patrick Sulem, Y. Ann Chen, Jonathan P. Tyrer, David C. Christiani, Yongyue Wei, Hongbing Shen, Zhibin Hu, Xiao-Ou Shu, Kouya Shiraishi, Atsushi Takahashi, Yohan Bossé, Ma'en Obeidat, David Nickle, Wim Timens, Matthew L. Freedman, Qiyuan Li, Daniela Seminara, Stephen J. Chanock, Jian Gong, Ulrike Peters, Stephen B. Gruber, Christopher I. Amos, Thomas A. Sellers, Douglas F. Easton, David J. Hunter, Christopher A. Haiman, Brian E. Henderson, Rayjean J. Hung
Journal: Cancer Research
Cancer Res (2016) 76 (17): 5103–5114.
DOI: https://doi.org/10.1158/0008-5472.CAN-15-2980
Published: 31 August 2016
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Includes: Supplementary data
Journal Articles

Abstract 2587: Comprehensive colorectal cancer risk prediction to inform personalized screening and intervention

Jihyoun Jeon, Sonja I. Berndt, Hermann Brenner, Peter T. Campbell, Andrew T. Chan, Jenny Chang-Claude, Mengmeng Du, Graham Giles, Jian Gong, Stephen B. Gruber, Tabitha A. Harrison, Michael Hoffmeister, Loic LeMarchand, Li Li, John D. Potter, Gad Rennert, Robert E. Schoen, Martha L. Slattery, Emily White, Michael O. Woods, Ulrike Peters, Li Hsu
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2587.
DOI: https://doi.org/10.1158/1538-7445.AM2016-2587
Published: 15 July 2016
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