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Journal Articles

Abstract 2658: NOS inhibition augments PI3K inhibitor-induced DNA damage and mesenchymal-to-epithelial transition in metaplastic breast cancer

Tejaswini P. Reddy, Akshjot Puri, Liliana Guzman-Rojas, Bijan Mahboubi, Wei Qian, Jianying Zhou, Baek Kim, Stacy Moulder, Helen Piwnica-Worms, Roberto Rosato, Jenny C. Chang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2658.
DOI: https://doi.org/10.1158/1538-7445.AM2022-2658
Published: 15 June 2022
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Journal Articles

Abstract P3-03-06: Prediction of response to neoadjuvant systemic therapy in triple negative breast cancer using baseline tumor MRI characteristics and imaging patterns of response

Mary S Guirguis, Beatriz E Adrada, Rosalind P Candelaria, Jia Sun, Gary J Whitman, Wei T Yang, Medine Boge, Rania M Mohamed, Nabil A Elshafeey, Deanna L Lane, Huong Le-Petross, Jessica WT Leung, Lumarie Santiago, Marion E Scoggins, David A Spak, Miral Patel, Frances Perez, Peng Wei, Debu Tripathy, Jason White, Elizabeth Ravenberg, Lei Huo, Jennifer Litton, Banu Arun, Vincente Valero, Alastair Thompson, Stacy Moulder, Clinton Yam, Gaiane M Rauch
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-03-06.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-03-06
Published: 15 February 2022
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Journal Articles

Abstract P3-05-01: Role of TRIM24 in metaplastic breast cancer and nomination of potential therapeutic targets

Vrutant Shah, Shucheng Miao, Clinton Yam, Jeffrey T Chang, Michelle Barton, Helen Piwnica-Worms, Stacy Moulder, Guillermina Lozano
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-05-01.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-05-01
Published: 15 February 2022
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Journal Articles

Abstract P5-17-04: Combined PI3K and NOS inhibition enhances efficacy of taxane-based chemotherapy in metaplastic breast cancer

Tejaswini P Reddy, Bijan Mahboubi, Roberto R. Rosato, Liliana Guzman-Rojas, Wei Qian, Jianying Zhou, Baek Kim, Stacy Moulder, Helen Piwnica-Worms, Jenny C. Chang
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P5-17-04.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P5-17-04
Published: 15 February 2022
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Journal Articles

Abstract P1-08-03: Deep learning for early prediction of neoadjuvant chemotherapy response in triple negative breast cancers

Zijian Zhou, Nabil A Elshafeey, David E Rauch, Beatriz E Adrada, Rosalind P Candelaria, Mary S Guirguis, Wei Yang, Medine Boge, Rania M Mohamed, Gary J Whitman, Deanna L Lane, Huong C Le-Petross, Jessica WT Leung, Lumarie Santiago, Marion E Scoggins, David A Spak, Miral M Patel, Frances Perez, Debu Tripathy, Vicente Valero, Clinton Yam, Stacy Moulder, Jason B White, Jong Bum Son, Mark D Pagel, Jingfei Ma
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-08-03.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P1-08-03
Published: 15 February 2022
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Journal Articles

Abstract P1-08-08: Forecasting treatment response to neoadjuvant systemic therapy in triple negative breast cancer viamathematical modeling and quantitative MRI

Chengyue Wu, Angela M. Jarrett, Zijian Zhou, Nabil Elshafeey, Beatriz E. Adrada, Rosalind P. Candelaria, Rania M. Mohamed, Medine Boge, Lei Huo, Jason White, Debu Tripathy, Vicente Valero, Jennifer Litton, Stacy Moulder, Clinton Yam, Jong Bum Son, Jingfei Ma, Gaiane M. Rauch, Thomas E. Yankeelov
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-08-08.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P1-08-08
Published: 15 February 2022
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Journal Articles

Abstract PS11-17: Combination PI3K and NOS targeted therapy for metaplastic breast cancer

Tejaswini Parlapalle Reddy, Roberto R Rosato, Liliana Guzman, Wei Qian, Jianying Zhou, Hongbin Wang, Helen Piwnica-Worms, Stacy Moulder, Jenny C Chang
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS11-17.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PS11-17
Published: 15 February 2021
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Abstract PS18-04: Prospective evaluation of patients with metaplastic (Mp) triple negative breast cancer (TNBC): Molecular characteristics and outcomes with neoadjuvant therapy (NAT)

Nour Abuhadra, Clinton Yam, Ryan Sun, Lei Huo, Jason White, Elizabeth Ravenberg, Beatriz Adrada, Aysegul Sahin, Jennifer Litton, Bora Lim, Naoto T Ueno, Banu Arun, Debu Tripathy, Senthil Damodaran, Rashmi Murthy, Vicente Valero, Gabriel Hortobagyi, Nuhad Ibrahim, Alastair Thompson, Anthony Lucci, Elizabeth Mittendorf, Stacy Moulder, Jeffrey Chang
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS18-04.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PS18-04
Published: 15 February 2021
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Journal Articles

Abstract PS4-05: Prospective evaluation of the gut microbiome and response to neoadjuvant therapy (NAT) in early-stage triple negative breast cancer (TNBC)

Nour Abuhadra, Chia-Chi Chang, Clinton Yam, Ryan Sun, Lei Huo, Jason White, Elizabeth E Ravenberg, Jennifer Litton, Bora Lim, Naoto T Ueno, Banu Arun, Debu Tripathy, Senthil Damodaran, Rashmi Murthy, Vicente Valero, Gabriel Hortobagyi, Nuhad Ibrahim, Alastair Thompson, Elizabeth Mittendorf, Stacy Moulder, Robert Jenq
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS4-05.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PS4-05
Published: 15 February 2021
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Journal Articles

Abstract PS7-12: Impact of race/ethnicity on triple negative breast cancer molecular features, treatment response and clinical outcomes in patients receiving neoadjuvant therapy

Mediget Teshome, Ryan Sun, Elizabeth E. Ravenberg, Abenaa Brewster, Mariana Chavez-MacGregor, Jason B. White, Stacy Moulder
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS7-12.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PS7-12
Published: 15 February 2021
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Journal Articles

Abstract PD6-07: Volumetric changes on longitudinal dynamic contrast enhanced MR imaging (DCE-MRI) as an early treatment response predictor to neoadjuvant systemic therapy (NAST) in triple negative breast cancer (TNBC) patients

Gaiane Margishvili Rauch, Adrada E Beatriz, Rosalind P Candelaria, Nabil Elshafeey, Abeer H Abdelhafez, Benjamin C Musall, Jia Sun, Medina Boge, Rania M.M Mohamed, Jong Bum Son, Shu Zhang, Jessica Leung, Deanna Lane, Marion Scoggins, David Spak, Elsa Arribas, Lumarie Santiago, Gary J Whitman, Huong T. Le-Petross, Tanya W Moseley, Jason B. White, Elizabeth Ravenberg, Ken-Pin Hwang, Peng Wei, Lei Huo, Jennifer K Litton, Vicente Valero, Debu Tripathy, Alastair M Thompson, Mark D Pagel, Jingfei Ma, Wei T Yang, Stacy Moulder
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PD6-07.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PD6-07
Published: 15 February 2021
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Journal Articles

Abstract PD6-06: Radiomic phenotypes from dynamic contrast-enhanced MRI (DCE-MRI) parametric maps for early prediction of response to neoadjuvant systemic therapy (NAST) in triple negative breast cancer (TNBC) patients

Nabil Elshafeey, Beatriz E Adrada, Rosalind P Candelaria, Abeer H Abdelhafez, Benjamin C Musall, Jia Sun, Medine Boge, Rania M.M Mohamed, Hagar S Mahmoud, Jong Bum Son, Aikaterini Kotrosou, Shu Zhang, Jessica Leung, Deanna Lane, Marion Scoggins, David Spak, Elsa Arribas, Lumarie Santiago, Gary J. Whitman, Huong T Le-Petross, Tanya W Moseley, Jason B White, Elizabeth Ravenberg, Ken-Pin Hwang, Peng Wei, Jennifer K Litton, Lei Huo, Debu Tripathy, Vicente Valero, Alastair M Thompson, Stacy Moulder, Wei T Yang, Mark D Pagel, Jingfei Ma, Gaiane M Rauch
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PD6-06.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PD6-06
Published: 15 February 2021
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Journal Articles

Abstract PD9-05: A tiered algorithm using mid-therapy ultrasound (US) response assessment and a novel gene expression signature (GES) improves the prediction of pathologic complete response (pCR) to neoadjuvant therapy (NAT) in triple-negative breast cancer (TNBC): Results from the ARTEMIS trial (NCT02276443)

Sahil Seth, Gaiane M Rauch, Beatriz Adrada, Helen Piwnica-Worms, Lei Hou, Alastair M Thompson, William F Symmans, Bora Lim, Jason White, Giulio F Draetta, Andrew Futreal, Jeffrey Chang, Stacy Moulder
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PD9-05.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PD9-05
Published: 15 February 2021
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Journal Articles

Abstract P2-16-09: Residual cancer burden in patients with early stage triple negative breast cancer who progress on anthracycline-based neoadjuvant chemotherapy in an ongoing clinical trial (ARTEMIS)

Haven Garber, Gaiane Rauch, Beatriz Adrada, Rosalind Candelaria, Elizabeth Mittendorf, Alastair Thompson, Jennifer Litton, Senthil Damodaran, Bora Lim, Banu Arun, Naoto Ueno, Vicente Valero, Nuhad Ibrahim, Rashmi Murthy, Debu Tripathy, Helen Piwnica-Worms, Fraser Symmans, Lei Huo, Stacy Moulder
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P2-16-09.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P2-16-09
Published: 15 February 2020
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Journal Articles

Abstract P2-16-08: Longitudinal response and selection under neoadjuvant systemic therapy (NAST) in triple-negative breast cancer (TNBC): Profiling results from a randomized, TNBC enrolling trial to confirm molecular profiling improves survival (ARTEMIS; NCT02276443)

Sahil Seth, Lei Huo, Suhas Vasaikar, Gaiane Rauch, Bora Lim, Jason White, Beatriz Adrada, Helen Piwnica-Worms, Naoto T Ueno, Alastair Mark Thompson, Elizabeth Mittendorf, Debashish Tripathy, Jennifer Keating Litton, William Fraser Symmans, Giulio Draetta, Andrew Futreal, Jeffrey Chang, Stacy Moulder
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P2-16-08.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P2-16-08
Published: 15 February 2020
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Journal Articles

Abstract P1-10-20: Serial TILs: Evaluating the role of mid-treatment tumor infiltrating lymphocytes (TIL) in predicting pathologic complete response (pCR) in early-stage triple negative breast cancer (TNBC)

Nour Abuhadra, Kenneth Hess, Jennifer Litton, Gaiane Rauch, Alastair Thompson, Bora Lim, Beatriz Adrada, Elizabeth Mittendorf, Senthil Damodaran, Rosalind Candelaria, Banu Arun, Wei Tse Yang, Naoto Ueno, Lumarie Santiago, Rashmi Murthy, Nuhad Ibrahim, Sahin Aysegul, William Symmans, Lei Huo, Stacy Moulder
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P1-10-20.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P1-10-20
Published: 15 February 2020
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Journal Articles

Abstract P1-03-01: A novel model to study to metaplastic TNBC

Vrutant Shah, Sabrina Stratton, Shiming Jiang, Jeffrey Chang, Helen Piwnica-Worms, Stacy Moulder, Michelle Barton
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P1-03-01.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P1-03-01
Published: 15 February 2020
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Journal Articles

Abstract 2070: Exploration of markers of synergistic lethality of PARP and PI3K-Akt-mTOR inhibitors in women's cancers

Marilyne Labrie, Zhenlin Ju, Jennifer K. Litton, Tae-Beom Kim, Sanghoon Lee, Ken Chen, Pamela T. Soliman, Michael Frumovitz, Larissa A. Meyer, Stacy Moulder, Amir A. Jazaeri, Karen H. Lu, Anil K. Sood, Robert L. Coleman, Gordon B. Mills, Shannon N. Westin
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2070.
DOI: https://doi.org/10.1158/1538-7445.AM2019-2070
Published: 01 July 2019
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Journal Articles

Abstract CT015: Phase I dose-escalation study of the allosteric AKT inhibitor BAY 1125976 in advanced solid cancer

Andreas Schneeweiss, Dagmer Hess, Markus Joerger, Andrea Varga, Stacy Moulder, Cynthia Ma, Ian Krop, Sara Hurvitz, Christine Rentzsch, Marion Rudolph, Oliver Boix, Gary Wilkinson, Lars Lindbom, Eleni Lagkadinou, Matthias Ocker
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT015.
DOI: https://doi.org/10.1158/1538-7445.AM2019-CT015
Published: 01 July 2019
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Journal Articles

Abstract 4669: Overcoming therapy resistance in stem cell-rich triple negative breast cancer through p38 MAP kinase inhibition

Petra den Hollander, Shruti Shah, Xinhui Zhou, Abena Redwood, Shi-Rong Cai, Mary Sobieski, David Brunell, Clifford Stephan, Peter Davies, Helen Piwnica-Worms, Stacy Moulder, W Fraser Symmans, Sendurai A. Mani
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4669.
DOI: https://doi.org/10.1158/1538-7445.AM2019-4669
Published: 01 July 2019
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