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Sriram Rajagopal
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Journal Articles

Abstract 11: Novel dual inhibitors of LSD1-HDAC6/8 for treatment of cancer

Dhanalakshmi Sivanandhan, Sridharan Rajagopal, Sreekala Nair, Chandru Gajendran, Dimpy Ghosh, P Nagaraj, Subramanyam J. Tantry, Purushottam Dewang, Mahanandeesha S. Hallur, Kannan Murugan, Srinatha K. C, Damodara Kuntrapaku, M Dilipkumar, R Sharma, S Meghashree, Durga Prasanna Kumar, Suraj P. Ingle, Mohd Zainuddin, A B. Vinod, Sriram Rajagopal
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 11.
https://doi.org/10.1158/1538-7445.AM2019-11
Published: 01 July 2019
View article titled, Abstract 11: Novel dual inhibitors of LSD1-HDAC6/8 for treatment of cancer
Journal Articles

Abstract 1382: Novel dual inhibitors of LSD1-HDAC6/8 for treatment of cancer

Sivanandhan Dhanalakshmi, Sridharan Rajagopal, Sreekala Nair, Chandru Gajendran, Dimpy Ghosh, Subramanyam Janardhan Tantry, Purushottam Dewang, Mahanandeesha Hallur, M Kannan, Srinatha KC, Damodara Kuntrapaku, M Dilipkumar, Radha Sharma, S Meghashree, D P. Kumar, Mohd Zainuddin, A B. Vinod, Sriram Rajagopal
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1382.
https://doi.org/10.1158/1538-7445.AM2018-1382
Published: 01 July 2018
View article titled, Abstract 1382: Novel dual inhibitors of LSD1-HDAC6/8 for treatment of cancer
Journal Articles

Abstract 5860: Novel, first-in-class dual inhibitors of lysine specific demethylase 1 (LSD1) and histone deacetylatse 1 (HDAC) for treatment of cancer

Dhanalakshmi Sivanandhan, Sreekala Nair, Subramaniyam Tantry, Sridharan Rajagopal, Mahanandeesha Hallur, Kannan M, Srinatha KC, Damodara K, Dilipkumar M, Chandru G, Dimpy Ghosh, Pradeep N, Anuj Kumar Singh, Mohd Zainuddin, Rudresh G, Radha Sharma, Meghashree S, Durga P. Kumar, Purushottam Dewang, Sriram Rajagopal
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5860.
https://doi.org/10.1158/1538-7445.AM2018-5860
Published: 01 July 2018
View article titled, Abstract 5860: Novel, first-in-class dual inhibitors of lysine specific demethylase 1 (LSD1) and histone deacetylatse 1 (HDAC) for treatment of cancer
Journal Articles

Abstract 4856: Novel, small-molecule PRMT5 inhibitors for treatment of cancer

Dhanalakshmi Sivanandhan, Shivani Garapaty, Saravanan Vadivelu, Guru Pavan Kumar Seerapu, Reshma Das, Ronodip Kar, Anuj Kumar Singh, Venkatesha Ashokkumar Venkateshappa, Natarajan Tamizharasan, Indu N. Swamy, Nagendra Nagaraju, Subramaniyam Kanagaraj, Sayanti Sarkar, Jagadish D. Tibhe, Rudresh G, Mohd Zainuddin, Saravanan Kandan, Sridharan Rajagopal, Sriram Rajagopal
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4856.
https://doi.org/10.1158/1538-7445.AM2018-4856
Published: 01 July 2018
View article titled, Abstract 4856: Novel, small-molecule PRMT5 inhibitors for treatment of cancer
Journal Articles

Abstract 5552: Novel, heterocyclic small molecule inhibitors of PD-1 and PD-L1 pathway

Sivanandhan Dhanalakshmi, Shivani Garapaty, Chandregowda Venkateshappa, Guru Pavan Seerapu, Reshma Das, Pradeep Nagaraj, Ronodip Kar, Anuj Kumar Singh, Venkatesha Ashokkumar Venkatesubbiah, Ramakishore VP Putta, Muralidhar Pendyala, Girisha Lokesh, Hari Madaka, Harikrishna Reddy Thummuru, Shikas AP, Prateeksha Anchan, Prathima Bhat, Rudresha G, Mohd Zainuddin, Krishnakumar V, Ramachandraiah Gosu, Rajendra Kristam, Jeyaraj DA, Sriram Rajagopal
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5552.
https://doi.org/10.1158/1538-7445.AM2018-5552
Published: 01 July 2018
View article titled, Abstract 5552: Novel, heterocyclic small molecule inhibitors of PD-1 and PD-L1 pathway
Journal Articles

Abstract 5578: Small molecule modulators to understand the role of IDO1 and TDO2 in cancer

Shivani Rao Garapaty, Dhanalakshmi Sivanandhan, Guru Pavan Kumar Seerapu, Surendra Naidu, Shalini Chakelam, Pradeep Nagaraj, Reshma Das, Saravanan Vadivelu, Pravin Iyer, Chandrika Mulakala, Kannan Murugan, Somnath Mondal, Anjali Gautam, Saravanan Kandan, Manish Kumar Thakur, Sridharan Rajagopal, Sriram Rajagopal
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5578.
https://doi.org/10.1158/1538-7445.AM2017-5578
Published: 01 July 2017
View article titled, Abstract 5578: Small molecule modulators to understand the role of IDO1 and TDO2 in cancer
Journal Articles

Abstract 3509: Novel dual inhibitors of LSD1-HDAC for treatment of cancer

Dhanalakshmi Sivanandhan, Sridharan Rajagopalan, Sreekala Nair, Purushottam Dewang, Durga Prasanna Kumar, Chandrika Mulakala, Lavanya Mahadevan, Neema Skariah, Venkata Giri Kavuru, Damodara Kuntrapaku, Suchitra Sajja, Mohammad Zainuddin, Krishnakumar V, Ritu Singh, Swarnakumari V, Ramachandraiah Gosu, Jayashree Aiyar, Pravin Iyer, Sriram Rajagopal
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3509.
https://doi.org/10.1158/1538-7445.AM2015-3509
Published: 01 August 2015
View article titled, Abstract 3509: Novel dual inhibitors of LSD1-HDAC for treatment of cancer
Journal Articles

DRF 8439: A novel transcriptional inhibitor of heparanase that blocks invasion and metastasis

Chandrasekar Nirmala, Sivaram Pillarisetti, Sriram Rajagopal
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 423.
Published: 01 April 2004
View article titled, DRF 8439: A novel transcriptional inhibitor of heparanase that blocks invasion and metastasis
Journal Articles

Preclinical evaluation of the anticancer activity of DRF-1042, a novel camptothecin analog targeting Topoisomerase-I.

Sriram Rajagopal, R. Ajaya Kumar, D. Subramanya, V. M. Sharma, T. V. R. S. Sastry, Peter J. Houghton, A. Venkateshwaralu, R. Rajagopalan
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 710.
Published: 01 April 2004
View article titled, Preclinical evaluation of the anticancer activity of DRF-1042, a novel camptothecin analog targeting Topoisomerase-I.
Journal Articles

Topoisomerase II Inhibition and Altered Kinetics of Formation and Repair of Nitrosourea and Cisplatin-induced DNA Interstrand Cross-Links and Cytotoxicity in Human Glioblastoma Cells

Francis Ali-Osman, Mitchel S. Berger, Sriram Rajagopal, Alexander Spence, Robert B. Livingston
Journal: Cancer Research
Cancer Res (1993) 53 (23): 5663–5668.
Published: 01 December 1993
View article titled, Topoisomerase II Inhibition and Altered Kinetics of Formation and Repair of Nitrosourea and Cisplatin-induced DNA Interstrand Cross-Links and Cytotoxicity in Human Glioblastoma Cells
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