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Spencer B. Gibson
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Journal Articles

Abstract 1891: Cross-resistance and synergy between idelalisib and bendamustine in chronic lymphocytic leukemia

Sara E. F. Kost, Ali Saleh, Edgard M. Mejia, Marina Mostafizar, Eric D. J. Bouchard, Versha Banerji, Aaron J. Marshall, Spencer B. Gibson, Sachin Katyal, James B. Johnston
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1891.
https://doi.org/10.1158/1538-7445.AM2018-1891
Published: 01 July 2018
View article titled, Abstract 1891: Cross-resistance and synergy between idelalisib and bendamustine in chronic lymphocytic leukemia
Journal Articles

Abstract 3976: Antihistamines as synergists with targeted therapies in chronic lymphocytic leukemia

Aaron P. Chanas-LaRue, James B. Johnston, Spencer B. Gibson
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3976.
https://doi.org/10.1158/1538-7445.AM2018-3976
Published: 01 July 2018
View article titled, Abstract 3976: Antihistamines as synergists with targeted therapies in chronic lymphocytic leukemia
Journal Articles

Abstract 4293: Siramesine and lapatinib induce ferroptosis in glioblastoma and lung adenocarcinoma cells

Anna R. Blankstein, Shumei Ma, Spencer B. Gibson
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4293.
https://doi.org/10.1158/1538-7445.AM2017-4293
Published: 01 July 2017
View article titled, Abstract 4293: Siramesine and lapatinib induce ferroptosis in glioblastoma and lung adenocarcinoma cells
Journal Articles

Abstract 5423: ZAP70 alters metabolism in chronic lymphocytic leukemic cells

Subhadip Das, RF Dielschneider, Elizabeth S. Henson, Spencer B. Gibson
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5423.
https://doi.org/10.1158/1538-7445.AM2017-5423
Published: 01 July 2017
View article titled, Abstract 5423: ZAP70 alters metabolism in chronic lymphocytic leukemic cells
Journal Articles

Abstract 2850: Role of shelterin proteins for telomere shortening in chronic lymphocytic leukemia

Ganchimeg Ishdorj, Sara EF Kost, Yunli Zang, Spencer B. Gibson, James B. Johnston
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2850.
https://doi.org/10.1158/1538-7445.AM2016-2850
Published: 15 July 2016
View article titled, Abstract 2850: Role of shelterin proteins for telomere shortening in chronic lymphocytic leukemia
Journal Articles

Abstract 281: Bendamustine has the biochemical properties of an alkylating agent that synergizes with nucleoside analogues in chronic lymphocytic leukemia

Sara EF Kost, Eric DJ Bouchard, Élise LaBossière, Xibiao Ye, Michelle L. Queau, William S. Liang, Versha Banerji, Spencer B. Gibson, Sachin Katyal, James B. Johnston
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 281.
https://doi.org/10.1158/1538-7445.AM2016-281
Published: 15 July 2016
View article titled, Abstract 281: Bendamustine has the biochemical properties of an alkylating agent that synergizes with nucleoside analogues in chronic lymphocytic leukemia
Journal Articles

Abstract 1000: Tyrosine kinase receptor EGFR regulates the switch between cell survival and cell death induced by autophagy under hypoxia in cancer cells

Spencer B. Gibson, Yongqiang Chen, Elizabeth S. Henson, Daniel Huang
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1000.
https://doi.org/10.1158/1538-7445.AM2015-1000
Published: 01 August 2015
View article titled, Abstract 1000: Tyrosine kinase receptor EGFR regulates the switch between cell survival and cell death induced by autophagy under hypoxia in cancer cells
Journal Articles

Abstract 4624: Clinical impact of telomere shortening in normal and leukemia cells in chronic lymphocytic leukemia

Lin Yang, Sara Beiggi, Yunli Zhang, Robert Schmidt, Spencer B. Gibson, James B. Johnston
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4624.
https://doi.org/10.1158/1538-7445.AM2015-4624
Published: 01 August 2015
View article titled, Abstract 4624: Clinical impact of telomere shortening in normal and leukemia cells in chronic lymphocytic leukemia
Journal Articles

Abstract 2555: The mechanism of action of bendamustine alone or in combination with nucleoside analogs in chronic lymphocytic leukemia

Sara E.F. Kost, Eric D.J. Bouchard, William S. Liang, Versha Banerji, Spencer B. Gibson, Sachin Katyal, James B. Johnston
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2555.
https://doi.org/10.1158/1538-7445.AM2015-2555
Published: 01 August 2015
View article titled, Abstract 2555: The mechanism of action of bendamustine alone or in combination with nucleoside analogs in chronic lymphocytic leukemia
Journal Articles

Abstract 3052: NAMPT inhibition induces mitochondrial dysfunction leading to apoptosis in chronic lymphocytic leukemia cells

Eric DJ Bouchard, Edgard M. Mejia, Iris Gehrke, Armando G. Poeppl, Donna Hewitt, James B. Johnston, Spencer B. Gibson, Grant M. Hatch, Versha Banerji
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3052.
https://doi.org/10.1158/1538-7445.AM2015-3052
Published: 01 August 2015
View article titled, Abstract 3052: NAMPT inhibition induces mitochondrial dysfunction leading to apoptosis in chronic lymphocytic leukemia cells
Journal Articles

Abstract 911: Tyrosine kinase inhibitor Gefitinib selectivley induces apoptosis in Zap70+ chronic lymphocytic leukemia cells and inhibits B cell receptor signaling.

Rebecca Dielschneider, Wenyan Xiao, Ju Yoon Yoon, Edward Noh, James B. Johnston, Spencer B. Gibson
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 911.
https://doi.org/10.1158/1538-7445.AM2013-911
Published: 15 April 2013
View article titled, Abstract 911: Tyrosine kinase inhibitor Gefitinib selectivley induces apoptosis in Zap70+ chronic lymphocytic leukemia cells and inhibits B cell receptor signaling.
Journal Articles

Abstract 597: The combination of valproic acid and fludarabine treatment induces a synergistic apoptotic response in chronic lymphocytic leukemia (CLL) patients involving the lysosomal protease cathepsin B.

Ju Yoon Yoon, David Szwajcer, Ganchimeg Ishdorj, Pat Benjaminson, Rajat Kumar, James B. Johnston, Spencer B. Gibson
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 597.
https://doi.org/10.1158/1538-7445.AM2013-597
Published: 15 April 2013
View article titled, Abstract 597: The combination of valproic acid and fludarabine treatment induces a synergistic apoptotic response in chronic lymphocytic leukemia (CLL) patients involving the lysosomal protease cathepsin B.
Journal Articles

Abstract 1906: Differential downstream effects of nicotinamide adenine dinucleotide (NAD) salvage pathway-inhibition in chronic lymphocytic leukemia (CLL) and multiple myeloma (MM).

Iris Gehrke, Armando Poeppl, James Johnston, Spencer B. Gibson, Versha Banerji
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1906.
https://doi.org/10.1158/1538-7445.AM2013-1906
Published: 15 April 2013
View article titled, Abstract 1906: Differential downstream effects of nicotinamide adenine dinucleotide (NAD) salvage pathway-inhibition in chronic lymphocytic leukemia (CLL) and multiple myeloma (MM).
Journal Articles

Abstract 4983: Correlation telomere shortening in chronic lymphocytic leukemia cells with oxidative stress and dysregulation of shelterin proteins

Ganchimeg Ishdorj, Sabine Mai, Yunli Zang, Spencer B. Gibson, James B. Johnston
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4983.
https://doi.org/10.1158/1538-7445.AM2012-4983
Published: 15 April 2012
View article titled, Abstract 4983: Correlation telomere shortening in chronic lymphocytic leukemia cells with oxidative stress and dysregulation of shelterin proteins
Journal Articles

Abstract 5505: Risk of second malignancies in patients with Chronic Lymphocytic Leukemia: A population based Canadian study

Sara Beiggi, Pascal J. Lambert, Marshall W. Pitz, Matthew D. Seftel, James B. Johnston, E. Jane Griffith, Spencer B. Gibson
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5505.
https://doi.org/10.1158/1538-7445.AM2012-5505
Published: 15 April 2012
View article titled, Abstract 5505: Risk of second malignancies in patients with Chronic Lymphocytic Leukemia: A population based Canadian study
Journal Articles

Abstract 4108: BH3 only Bcl-2 family member BNIP3 repressed expression of death receptor 5 (DR5) in glioblastoma cells: Implications for regulation of the tumor necrosis factor related apoptosis inducing ligand (TRAIL) cell death pathway

Elizabeth S. Henson, Teralee R. Burton, Meghan B. Azad, David D. Eisenstat, Spencer B. Gibson
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4108.
https://doi.org/10.1158/1538-7445.AM2011-4108
Published: 15 April 2011
View article titled, Abstract 4108: BH3 only Bcl-2 family member BNIP3 repressed expression of death receptor 5 (DR5) in glioblastoma cells: Implications for regulation of the tumor necrosis factor related apoptosis inducing ligand (TRAIL) cell death pathway
Journal Articles

Abstract 1762: Clinical relevance of plasma IL-6 and IL-6 levels in chronic lymphocytic leukemia (CLL)

James B. Johnston, Ju-Yoon Yoon, Sunjay Lakhi, Brenda Kuschak, Donna Hewitt, Spencer B. Gibson
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1762.
https://doi.org/10.1158/1538-7445.AM10-1762
Published: 15 April 2010
View article titled, Abstract 1762: Clinical relevance of plasma IL-6 and IL-6 levels in chronic lymphocytic leukemia (CLL)
Journal Articles

The pro-cell death Bcl-2 family member, BNIP3 is mutated in breast tumors and this mutation increases resistance to hypoxia-induced cell death in breast cancer cell lines

Nicolle A. Bristow, Elizabeth S. Henson, Niki Vegh-Yarema, David D. Eisenstat, Spencer B. Gibson
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 960.
Published: 15 April 2006
View article titled, The pro-cell death Bcl-2 family member, BNIP3 is mutated in breast tumors and this mutation increases resistance to hypoxia-induced cell death in breast cancer cell lines
Journal Articles

Hypoxia induces beclin-1 expression and autophagic cell death in apoptosis-competent cells

Meghan B. Webb, Elizabeth S. Henson, Yongqiang Chen, Eileen M. Mcmillan-Ward, Sara J. Israels, David D. Eisenstat, Spencer B. Gibson
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 964.
Published: 15 April 2006
View article titled, Hypoxia induces beclin-1 expression and autophagic cell death in apoptosis-competent cells
Journal Articles

The S100A7-c-Jun Activation Domain Binding Protein 1 Pathway Enhances Prosurvival Pathways in Breast Cancer

Ethan D. Emberley, Yulian Niu, Linda Curtis, Sandra Troup, Sanat K. Mandal, Jeffery N. Myers, Spencer B. Gibson, Leigh C. Murphy, Peter H. Watson
Journal: Cancer Research
Cancer Res (2005) 65 (13): 5696–5702.
https://doi.org/10.1158/0008-5472.CAN-04-3927
Published: 01 July 2005
View article titled, The S100A7-c-Jun Activation Domain Binding Protein 1 Pathway Enhances Prosurvival Pathways in Breast Cancer
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