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Sooryanarayana Varambally
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Journal Articles

Abstract 585: Regorafenib antitumor immune response is enhanced by a novel drug combination in CRC syngeneic model

Prachi Bajpai, Farrukh Afaq, Sameer Al Diffalha, Sumit Agarwal, Hyung Gyoon Kim, Dennis Otali, Sooryanarayana Varambally, Ashish Manne, Ravi Paluri, Moh’d Khushman, Upender Manne
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 585.
https://doi.org/10.1158/1538-7445.AM2024-585
Published: 22 March 2024
View article titled, Abstract 585: Regorafenib antitumor immune response is enhanced by a novel drug combination in CRC syngeneic model
Journal Articles

Abstract 2270: UALCAN Mobile, An app for cancer gene expression data analysis

Sooryanarayana Varambally, Darshan Shimoga Chandrashekar, Gopi Chand Puli, Santhosh Kumar Karthikeyan, Upender Manne, Chad J. Creighton, Sidarth Kumar
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2270.
https://doi.org/10.1158/1538-7445.AM2024-2270
Published: 22 March 2024
View article titled, Abstract 2270: UALCAN Mobile, An app for cancer gene expression data analysis
Journal Articles

Abstract 5973: Targeting prolyl 4-hydroxylase subunit alpha 1 with a small molecule inhibitor, diethyl-pythiDC, reduces pancreatic ductal adenocarcinoma growth and metastasis

Farrukh Afaq, Mohd Khushman, Prachi Bajpai, Sameer Al Diffalha, Dennis Otali, Sooryanarayana Varambally, Upender Manne
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5973.
https://doi.org/10.1158/1538-7445.AM2024-5973
Published: 22 March 2024
View article titled, Abstract 5973: Targeting prolyl 4-hydroxylase subunit alpha 1 with a small molecule inhibitor, diethyl-pythiDC, reduces pancreatic ductal adenocarcinoma growth and metastasis
Journal Articles

Abstract A006: Differential gene expression to delineate racial disparities in the molecular landscape of pancreatic ductal adenocarcinoma

Prachi Bajpai, Ravi Paluri, Sameer Al Diffalha, Darshan S. Chandrashekar, Farrukh Afaq, Ryan Bash, C. Ryan Miller, Sooryanarayana Varambally, Moh’d Khushman, Upender Manne
Journal: Cancer Research
Cancer Res (2024) 84 (2_Supplement): A006.
https://doi.org/10.1158/1538-7445.PANCA2023-A006
Published: 16 January 2024
View article titled, Abstract A006: Differential gene expression to delineate racial disparities in the molecular landscape of pancreatic ductal adenocarcinoma
Journal Articles

Abstract 4969: Enhancing the efficacy of small molecule inhibitor of TRIP13 in prostate cancer using thymoquinone

Santosh K. Singh, Manoj K. Mishra, Sooryanarayana Varambally, Rajesh Singh
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4969.
https://doi.org/10.1158/1538-7445.AM2023-4969
Published: 04 April 2023
View article titled, Abstract 4969: Enhancing the efficacy of small molecule inhibitor of TRIP13 in prostate cancer using thymoquinone
Journal Articles

Abstract 6586: Updates to UALCAN, a comprehensive cancer proteogenomic data analysis platform for discovery research

Darshan Shimoga Chandrashekar, Sooryanarayana Varambally, Santhosh Kumar Karthikeyan, Praveen Kumar Korla, Henalben Patel, Mohammad Athar, Upender Manne, George J. Netto, Ahmedur Rahman Shovon, Sidharth Kumar, Zhaohui S. Qin, Chad J. Crieghton
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6586.
https://doi.org/10.1158/1538-7445.AM2023-6586
Published: 04 April 2023
View article titled, Abstract 6586: Updates to UALCAN, a comprehensive cancer proteogenomic data analysis platform for discovery research
Journal Articles

Abstract 1710: Pharmacologic targeting or silencing of TRIP13 reduces progression of pancreatic ductal adenocarcinoma

Farrukh Afaq, Sumit Agarwal, Prachi Bajpai, Hyung-Gyoon Kim, Sameer Al Diffalha, Shajan P. Sugandha, Moh'd Khushman, Sooryanarayana Varambally, Upender Manne
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1710.
https://doi.org/10.1158/1538-7445.AM2023-1710
Published: 04 April 2023
View article titled, Abstract 1710: Pharmacologic targeting or silencing of TRIP13 reduces progression of pancreatic ductal adenocarcinoma
Journal Articles

Abstract 1297: BZW2 a potential target to inhibit colorectal cancer growth and metastasis

Prachi Bajpai, Sumit Agarwal, Farrukh Afaq, Michael Behring, Hyung-Gyoon Kim, Darshan Shimoga Chandrashekar, Shajan Peter, Sameer Al Diffalha, Moh’d Khushman, Andreas Seeber, Sooryanarayana Varambally, Upender Manne
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1297.
https://doi.org/10.1158/1538-7445.AM2023-1297
Published: 04 April 2023
View article titled, Abstract 1297: BZW2 a potential target to inhibit colorectal cancer growth and metastasis
Journal Articles

Abstract 1003: The prognostic significance of prolyl 4-hydroxylase subunit alpha 1 and the therapeutic efficacy of diethyl-pythiDC, its small molecule inhibitor, in pancreatic ductal adenocarcinoma

Moh'd Khushman, Farrukh Afaq, Prachi Bajpai, Sameer Al Diffalha, Darryl Outlaw, Grant R. Williams, Rojymon Jacob, Kondal Rao Kyanam Kabir, Ali Ahmed, Peter Shajan, Sooryanarayana Varambally, Upender Manne
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1003.
https://doi.org/10.1158/1538-7445.AM2023-1003
Published: 04 April 2023
View article titled, Abstract 1003: The prognostic significance of prolyl 4-hydroxylase subunit alpha 1 and the therapeutic efficacy of diethyl-pythiDC, its small molecule inhibitor, in pancreatic ductal adenocarcinoma
Journal Articles

Abstract 2701: Multivariate transcriptome analysis identifies networks and key drivers of metastatic castration-resistant prostate cancer

Lawrence P. McKinney, Rajesh Singh, I. King Jordan, Sooryanarayana Varambally, Martin G. Sanda, Eric B. Dammer, James W. Lillard
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2701.
https://doi.org/10.1158/1538-7445.AM2022-2701
Published: 15 June 2022
View article titled, Abstract 2701: Multivariate transcriptome analysis identifies networks and key drivers of metastatic castration-resistant prostate cancer
Journal Articles

Abstract P3-09-14: Whole exome sequencing of matched primary and metastatic triple-negative breast cancer samples

Jaspreet Kaur, Darshan S. Chandrashekar, Zsuzsanna Varga, Emiel Janssen, Khanjan Gandhi, Karuna Mittal, Umay Kiraz, Sooryanarayana Varambally, Ritu Aneja
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-14.
https://doi.org/10.1158/1538-7445.SABCS21-P3-09-14
Published: 15 February 2022
View article titled, Abstract P3-09-14: Whole exome sequencing of matched primary and metastatic triple-negative breast cancer samples
Journal Articles

Abstract P2-12-24: Exosomal metabolic signatures are associated with differential response to neoadjuvant chemotherapy in patients with breast cancer

Shriya Joshi, Chakravarthy Garalapati, Shristi Bhattarai, Darshan Shimoga Chandrashekar, Sooryanarayana Varambally, Gagan Deep, Ritu Aneja
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P2-12-24.
https://doi.org/10.1158/1538-7445.SABCS21-P2-12-24
Published: 15 February 2022
View article titled, Abstract P2-12-24: Exosomal metabolic signatures are associated with differential response to neoadjuvant chemotherapy in patients with breast cancer
Journal Articles

Abstract LB245: TRIM29 mediates metastasis though hypoxia-regulated proteins in microsatellite-stable and p53-mutated colorectal cancers

Sumit Agarwal, Michael Behring, Prachi Bajpai, Amr Elkohly, Hyung-Gyoon Kim, Darshan S. Chandrashekar, Nirzari Gupta, Sameer Al Diffalha, Sooryanarayana Varambally, Upender Manne
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB245.
https://doi.org/10.1158/1538-7445.AM2021-LB245
Published: 01 July 2021
View article titled, Abstract LB245: TRIM29 mediates metastasis though hypoxia-regulated proteins in microsatellite-stable and p53-mutated colorectal cancers
Journal Articles

EZH2-Targeted Therapies in Cancer: Hype or a Reality

Marie-Lisa Eich, Mohammad Athar, James E. Ferguson, III, Sooryanarayana Varambally
Journal: Cancer Research
Cancer Res (2020) 80 (24): 5449–5458.
https://doi.org/10.1158/0008-5472.CAN-20-2147
Published: 15 December 2020
View article titled, EZH2-Targeted Therapies in Cancer: Hype or a Reality
Open the PDF for EZH2-Targeted Therapies in Cancer: Hype or a Reality in another window
Includes: Supplementary data
Journal Articles

Abstract 2012: Recurrent rearrangements of NAALADL2 in prostate, breast, cervical, head and neck and lung squamous cell carcinoma

Pavithra D. Arachchige, Shannon Carskadon, James Hu, Justin Fernando, Darshan S. Chandrashekar, Nilesh S. Gupta, Sean R. Williamson, Dhananjay A. Chitale, Craig G. Rogers, James O. Peabody, Mani Menon, Tarek A. Bismar, Evelyn Jiagge, Sooryanarayana Varambally, Nallasivam Palanisamy
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2012.
https://doi.org/10.1158/1538-7445.AM2020-2012
Published: 15 August 2020
View article titled, Abstract 2012: Recurrent rearrangements of NAALADL2 in prostate, breast, cervical, head and neck and lung squamous cell carcinoma
Journal Articles

Abstract 2481: Developing analysis platform for pan-cancer study of DNA methylation, mirna and lncrna expression based on tumor subtypes using TCGA data

Darshan Shimoga Chandrashekar, Chad J. Creighton, Israel Ponce-Rodriguez, Sooryanarayana Varambally
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2481.
https://doi.org/10.1158/1538-7445.AM2019-2481
Published: 01 July 2019
View article titled, Abstract 2481: Developing analysis platform for pan-cancer study of DNA methylation, mirna and lncrna expression based on tumor subtypes using TCGA data
Journal Articles

Abstract 915: Pseudogene-associated recurrent gene fusion in prostate cancer

Balabhadrapatruni V. S. K. Chakravarthi, Shanker Kalyana-Sundaram, Pavithra D. Arachchige, Shannon Carskadon, Satya S. Pathi, Mireya Diaz-Insua, Craig Rogers, James Peabody, Clara Hwang, Mani Menon, Sean Williamson, Gupta Nilesh, Sooryanarayana Varambally, Nallasivam Palanisamy
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 915.
https://doi.org/10.1158/1538-7445.AM2019-915
Published: 01 July 2019
View article titled, Abstract 915: Pseudogene-associated recurrent gene fusion in prostate cancer
Journal Articles

Abstract LB-247: 9cis-retinoic UAB30 inhibits UVB-induced pro-inflammatory cytokines/chemokines signaling via targeting Bromodomain-4

Mohammad Waseem, Mahendra P. Kashyap, Changzhao Li, Sandeep C. Chaudhary, Darshan S. Chandrashekar, Venkatram R. Atigadda, Sooryanarayana Varambally, Craig A. Elmets, Mohammad Athar
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-247.
https://doi.org/10.1158/1538-7445.AM2019-LB-247
Published: 01 July 2019
View article titled, Abstract LB-247: 9cis-retinoic UAB30 inhibits UVB-induced pro-inflammatory cytokines/chemokines signaling via targeting Bromodomain-4
Journal Articles

Abstract 5247: Overexpression of methylenetetrahydrofolate dehydrogenase 1 like (MTHFD1L) in bladder cancer: A potential therapeutic target

Marie-Lisa Eich, Maria D. Rodriguez Pena, Darshan S. Chandrashekar, Jennifer B. Gordetsky, George J. Netto, Sooryanarayana Varambally
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5247.
https://doi.org/10.1158/1538-7445.AM2019-5247
Published: 01 July 2019
View article titled, Abstract 5247: Overexpression of methylenetetrahydrofolate dehydrogenase 1 like (MTHFD1L) in bladder cancer: A potential therapeutic target
Journal Articles

Abstract 851: MicroRNA-124 modulated collagen-prolyl hydroxylase P4HA1 expression regulates colon cancer progression

Sumit Agarwal, Balabhadrapatruni V. Chakravarthi, Michael Behring, Hyung-Gyoon Kim, Kevin Hale, Abduljalil M. Alsubaie, Sameer Al Diffalha, Shajan P. Sugandha, Sooryanarayana Varambally, Upender Manne
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 851.
https://doi.org/10.1158/1538-7445.AM2019-851
Published: 01 July 2019
View article titled, Abstract 851: MicroRNA-124 modulated collagen-prolyl hydroxylase P4HA1 expression regulates colon cancer progression