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Journal Articles

Abstract 363: Exploiting Rb-deficiency: Dual inhibition of TRIP13 and Aurora A as a path to mitotic catastrophe

Free
Lacin Yapindi, Soma Ghosh, Li Shen, Jing Wang, Faye M. Johnson
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 363.
https://doi.org/10.1158/1538-7445.AM2025-363
Published: 21 April 2025
View articletitled, Abstract 363: Exploiting Rb-deficiency: Dual inhibition of TRIP13 and Aurora A as a path to mitotic catastrophe
Journal Articles

Abstract 3094: Aurora-A inhibition sensitizes HPV-driven cancers to anti-CTLA-4 immunotherapy by modulating the tumor immune microenvironment

Free
Soma Ghosh, Madison P. O’Hara, Tuhina Mazumdar, Lacin Yapindi, Li Shen, Jing Wang, Mitchell J. Frederick, Jagannadha K. Sastry, Faye M. Johnson
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3094.
https://doi.org/10.1158/1538-7445.AM2025-3094
Published: 21 April 2025
View articletitled, Abstract 3094: Aurora-A inhibition sensitizes HPV-driven cancers to anti-CTLA-4 immunotherapy by modulating the tumor immune microenvironment
Journal Articles

Abstract PR007: The combination of TRIP13 and Aurora kinase A inhibition caused cell cycle specific DNA damage and death in Rb-deficient cancers

Free
Lacin Yapindi, Soma Ghosh, Tuhina Mazumdar, Faye M. Johnson
Journal: Cancer Research
Cancer Res (2024) 84 (1_Supplement): PR007.
https://doi.org/10.1158/1538-7445.DNAREPAIR24-PR007
Published: 09 January 2024
View articletitled, Abstract PR007: The combination of TRIP13 and Aurora kinase A inhibition caused cell cycle specific DNA damage and death in Rb-deficient cancers
Journal Articles

Abstract 1564: Novel combination of TRIP13 and Aurora kinase A inhibition demonstrated extensive DNA damage and immunogenic cell death in RB-deficient cancers

Free
Soma Ghosh, Tuhina Mazumdar, Lacin Yapindi, Pragya Sinha, Jagannadha Sastry, Faye M. Johnson
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1564.
https://doi.org/10.1158/1538-7445.AM2023-1564
Published: 04 April 2023
View articletitled, Abstract 1564: Novel combination of TRIP13 and Aurora kinase A inhibition demonstrated extensive DNA damage and immunogenic cell death in RB-deficient cancers
Journal Articles

Abstract 5021: Preclinical evaluation of immunomodulatory effects of aurora kinase inhibition in HPV+ cancers

Free
Pragya Sinha, Soma Ghosh, Faye M. Johnson, Jagannadha K. Sastry
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5021.
https://doi.org/10.1158/1538-7445.AM2023-5021
Published: 04 April 2023
View articletitled, Abstract 5021: Preclinical evaluation of immunomodulatory effects of aurora kinase inhibition in HPV+ cancers
Journal Articles

Sustained Aurora Kinase B Expression Confers Resistance to PI3K Inhibition in Head and Neck Squamous Cell Carcinoma

Available to Purchase
Pooja A. Shah, Vaishnavi Sambandam, Anne M. Fernandez, Hongyun Zhao, Tuhina Mazumdar, Li Shen, Qi Wang, Kazi M. Ahmed, Soma Ghosh, Mitchell J. Frederick, Jing Wang, Faye M. Johnson
Journal: Cancer Research
Cancer Res (2022) 82 (23): 4444–4456.
https://doi.org/10.1158/0008-5472.CAN-22-1175
Published: 02 December 2022
View articletitled, Sustained Aurora Kinase B Expression Confers Resistance to PI3K Inhibition in Head and Neck Squamous Cell Carcinoma
Open the PDF for Sustained Aurora Kinase B Expression Confers Resistance to PI3K Inhibition in Head and Neck Squamous Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 1858: Rb deficient HPV+ HNSCC experienced enhanced sensitivity to aurora kinase inhibitors by altering the balance of MAD2 and TRIP13 levels

Free
Soma Ghosh, Tuhina Mazumdar, Wei Xu, Reid T. Powell, Clifford Stephan, Li Shen, Curtis R. Pickering, Jing Wang, Faye M. Johnson
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1858.
https://doi.org/10.1158/1538-7445.AM2022-1858
Published: 15 June 2022
View articletitled, Abstract 1858: Rb deficient HPV+ HNSCC experienced enhanced sensitivity to aurora kinase inhibitors by altering the balance of MAD2 and TRIP13 levels
Journal Articles

Abstract 368: Aurora kinase inhibitors cause cell death in HPV+ cells: A plausible treatment option for HPV+ cancers

Free
Tuhina Mazumdar, Li Shen, Wei Xu, Soma Ghosh, Reid T. Powell, Clifford Stephan, Curtis R. Pickering, Jeffery N. Myers, Jing Wang, Faye M. Johnson
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 368.
https://doi.org/10.1158/1538-7445.AM2021-368
Published: 01 July 2021
View articletitled, Abstract 368: Aurora kinase inhibitors cause cell death in HPV+ cells: A plausible treatment option for HPV+ cancers
Journal Articles

Abstract 3580: Acetaldehyde and drug hypersensitivities of Fanconi anemia defects: Implications for cancer initiation, prevention, and therapy.

Free
Soma Ghosh, Surojit Sur, Sashidhar R. Yerram, Carlo Rago, Anil K. Bhunia, M. Zulfiquer Hossain, Bogdan C. Paun, Yunzhao R. Ren, Christine A. Iacobuzio-Donahue, Nilofer A. Azad, Scott E. Kern
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3580.
https://doi.org/10.1158/1538-7445.AM2013-3580
Published: 15 April 2013
View articletitled, Abstract 3580: Acetaldehyde and drug hypersensitivities of Fanconi anemia defects: Implications for cancer initiation, prevention, and therapy.
Journal Articles

Abstract 614: Biological clues to potent DNA-damaging activities in food and flavoring.

Free
Mohammad Zulfiquer Hossain, Samuel F. Gilbert, Kalpesh Patel, Soma Ghosh, Anil K. Bhunia, Scott E. Kern
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 614.
https://doi.org/10.1158/1538-7445.AM2013-614
Published: 15 April 2013
View articletitled, Abstract 614: Biological clues to potent DNA-damaging activities in food and flavoring.