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Journal Articles

A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair

Cancer Res (2021) 81 (24): 6171–6182.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-1415

Published: 15 December 2021

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Includes: Supplementary data

Journal Articles

Truncated ASPP2 Drives Initiation and Progression of Invasive Lobular Carcinoma via Distinct Mechanisms

Koen Schipper, Anne Paulien Drenth, Eline van der Burg, Samuel Cornelissen, Sjoerd Klarenbeek, Micha Nethe, Jos Jonkers

Cancer Res (2020) 80 (7): 1486–1497.

DOI: https://doi.org/10.1158/0008-5472.CAN-19-3607

Published: 02 April 2020

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Includes: Supplementary data

Journal Articles

Transcriptomics and Transposon Mutagenesis Identify Multiple Mechanisms of Resistance to the FGFR Inhibitor AZD4547

Sjors M. Kas, Julian R. de Ruiter, Koen Schipper, Eva Schut, Lorenzo Bombardelli, Ellen Wientjens, Anne Paulien Drenth, Renske de Korte-Grimmerink, Sunny Mahakena, Christopher Phillips, Paul D. Smith, Sjoerd Klarenbeek, Koen van de Wetering, Anton Berns, Lodewyk F.A. Wessels, Jos Jonkers

Cancer Res (2018) 78 (19): 5668–5679.

DOI: https://doi.org/10.1158/0008-5472.CAN-18-0757

Published: 01 October 2018

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Includes: Supplementary data

Journal Articles

Abstract 1041: XenofilteR: Computational dissection of mouse and human reads in PDX and xenograft sequence data

Oscar Krijgsman, Roelof JC Kluin, Kristel Kemper, Thomas Kuilman, Julian R. de Ruiter, Vivek Iyer, Josep V. Forment, Paulien Cornelissen-Steijger, Iris de Rink, Petra ter Brugge, Ji-Ying Song, Sjoerd Klarenbeek, Ultan McDermott, Jos Jonkers, Arno Velds, David J. Adams, Daniel S. Peeper

Cancer Res (2018) 78 (13_Supplement): 1041.

DOI: https://doi.org/10.1158/1538-7445.AM2018-1041

Published: 01 July 2018

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Journal Articles

Abstract 2687: Rapid in vivo testing of tumor suppressors in ILC by CRISPR-Cas9 mediated somatic gene editing of the mammary gland

Stefano Annunziato, Sjors Kas, Micha Nethe, Hatice Yucel, Jessica del Bravo, Colin Pritchard, Rahmen Bin Ali, Bas van Gerwen, Bjorn Siteur, Anne Paulien Drenth, Eva Schut-Kregel, Sjoerd Klarenbeek, Ivo Huijbers, Martine van Miltenburg, Jos Jonkers

Cancer Res (2016) 76 (14_Supplement): 2687.

DOI: https://doi.org/10.1158/1538-7445.AM2016-2687

Published: 15 July 2016

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Journal Articles

Abstract 2394: Cancer-associated fibroblasts in invasive lobular breast carcinoma

Mirjam C. Boelens, Ellen Wientjens, Eva Schut, Sjoerd Klarenbeek, Karin E. de Visser, Jos Jonkers

Cancer Res (2015) 75 (15_Supplement): 2394.

DOI: https://doi.org/10.1158/1538-7445.AM2015-2394

Published: 01 August 2015

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Journal Articles

Abstract B77: The role of fibroblasts in invasive lobular breast carcinoma

Mirjam C. Boelens, Ellen Wientjens, Eva Schut, Sjoerd Klarenbeek, Karin E. de Visser, Jos Jonkers

Cancer Res (2015) 75 (1_Supplement): B77.

DOI: https://doi.org/10.1158/1538-7445.CHTME14-B77

Published: 12 January 2015

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Journal Articles

Abstract A52: Loss of p120-catenin induces metastatic progression of breast cancer by inducing anoikis resistance and augmenting growth factor receptor signaling

Ron C.J. Schackmann, Sjoerd Klarenbeek, Eva J. Vlug, Suzan Stelloo, Miranda van Amersfoort, Milou Tenhagen, Tanya M. Braumuller, Jeroen F. Vermeulen, Petra van der Groep, Ton Peeters, Elsken van der Wall, Paul J. van Diest, Jos Jonkers, Patrick W.B. Derksen

Cancer Res (2013) 73 (19_Supplement): A52.

DOI: https://doi.org/10.1158/1538-7445.FBCR13-A52

Published: 15 May 2014

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Journal Articles

Loss of p120-Catenin Induces Metastatic Progression of Breast Cancer by Inducing Anoikis Resistance and Augmenting Growth Factor Receptor Signaling

Cancer Res (2013) 73 (15): 4937–4949.

DOI: https://doi.org/10.1158/0008-5472.CAN-13-0180

Published: 31 July 2013

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Includes: Supplementary data

Journal Articles

A Preclinical Mouse Model of Invasive Lobular Breast Cancer Metastasis

Chris W. Doornebal, Sjoerd Klarenbeek, Tanya M. Braumuller, Christiaan N. Klijn, Metamia Ciampricotti, Cheei-Sing Hau, Markus W. Hollmann, Jos Jonkers, Karin E. de Visser

Cancer Res (2013) 73 (1): 353–363.

DOI: https://doi.org/10.1158/0008-5472.CAN-11-4208

Published: 02 January 2013

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Includes: Supplementary data

Journal Articles

Abstract 3295: Systematic in vivo analysis of PI3K pathway aberrations in a mouse model for invasive lobular carcinoma

Martine H. van Miltenburg, Sjoerd Klarenbeek, Tanya Braumuller, Linda Henneman, Rahmen Bin Ali, Ivo Huijbers, Paul Krimpenfort, Anton Berns, Jos Jonkers

Cancer Res (2012) 72 (8_Supplement): 3295.

DOI: https://doi.org/10.1158/1538-7445.AM2012-3295

Published: 15 April 2012

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Journal Articles

Abstract 2140: Finding co-occurrence and mutual exclusiveness in DNA copy number data

Christiaan N. Klijn, Jan Bot, Sjoerd Klarenbeek, Ingrid van der Heijden, David J. Adams, Marcel Reinders, Lodewyk Wessels, Jos Jonkers

Cancer Res (2010) 70 (8_Supplement): 2140.

DOI: https://doi.org/10.1158/1538-7445.AM10-2140

Published: 15 April 2010

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NARROW

A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair

Truncated ASPP2 Drives Initiation and Progression of Invasive Lobular Carcinoma via Distinct Mechanisms

Transcriptomics and Transposon Mutagenesis Identify Multiple Mechanisms of Resistance to the FGFR Inhibitor AZD4547

Abstract 1041: XenofilteR: Computational dissection of mouse and human reads in PDX and xenograft sequence data

Abstract 2687: Rapid in vivo testing of tumor suppressors in ILC by CRISPR-Cas9 mediated somatic gene editing of the mammary gland

Abstract 2394: Cancer-associated fibroblasts in invasive lobular breast carcinoma

Abstract B77: The role of fibroblasts in invasive lobular breast carcinoma

Abstract A52: Loss of p120-catenin induces metastatic progression of breast cancer by inducing anoikis resistance and augmenting growth factor receptor signaling

Loss of p120-Catenin Induces Metastatic Progression of Breast Cancer by Inducing Anoikis Resistance and Augmenting Growth Factor Receptor Signaling

A Preclinical Mouse Model of Invasive Lobular Breast Cancer Metastasis

Abstract 3295: Systematic in vivo analysis of PI3K pathway aberrations in a mouse model for invasive lobular carcinoma

Abstract 2140: Finding co-occurrence and mutual exclusiveness in DNA copy number data

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