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Journal Articles

Bruton Tyrosine Kinase Is a Therapeutic Target in Stem-like Cells from Multiple Myeloma

Ye Yang, Jumei Shi, Zhimin Gu, Mohamed E. Salama, Satyabrata Das, Erik Wendlandt, Hongwei Xu, Junwei Huang, Yi Tao, Mu Hao, Reinaldo Franqui, Dana Levasseur, Siegfried Janz, Guido Tricot, Fenghuang Zhan

Cancer Res (2015) 75 (3): 594–604.

https://doi.org/10.1158/0008-5472.CAN-14-2362

Published: 01 February 2015

View article titled, Bruton Tyrosine Kinase Is a Therapeutic Target in Stem-like Cells from Multiple Myeloma

Journal Articles

Abstract A8: Network analysis of retroviral and transposon mutagenesis sites in B cell lymphoma converges on MyD88 pathway

Samuel Lifton, Alicia Olivier, Adam Dupuy, Wendy Dubois, Linda Wolff, Siegfried Janz

Cancer Res (2012) 72 (13_Supplement): A8.

https://doi.org/10.1158/1538-7445.CSB12-A8

Published: 06 November 2014

View article titled, Abstract A8: Network analysis of retroviral and transposon mutagenesis sites in B cell lymphoma converges on MyD88 pathway

Journal Articles

Abstract 1834: Noncoding RNAs of the 8q24 locus: Consequences of the over-expression or suppression of miR-1204 and PVT1 in developing B cells.

Konrad Huppi, Oliver L. Ou, Jason J. Pitt, Brady Wahlberg, Tamara L. Jones, Vishala Neppalli, Siegfried Janz, Natasha J. Caplen

Cancer Res (2013) 73 (8_Supplement): 1834.

https://doi.org/10.1158/1538-7445.AM2013-1834

Published: 15 April 2013

View article titled, Abstract 1834: Noncoding RNAs of the 8q24 locus: Consequences of the over-expression or suppression of miR-1204 and PVT1 in developing B cells.

Journal Articles

Abstract 1672: Population prevalence of consensus translocations in follicular and mantle cell lymphomas

Carsten Hirt, Manuela Meier, Kelly Yu, Frank Schüler, Siegfried Janz, Gottfried Dölken, Charles S. Rabkin

Cancer Res (2012) 72 (8_Supplement): 1672.

https://doi.org/10.1158/1538-7445.AM2012-1672

Published: 15 April 2012

View article titled, Abstract 1672: Population prevalence of consensus translocations in follicular and mantle cell lymphomas

Journal Articles

Abstract LB-181: Piperlongumine inhibits growth and survival of human Burkitt lymphoma by downregulating NF-κB, c-Myc and LMP1

Seong-Su Han, Dong-Ju Son, Hwakyung Yun, Siegfried Janz

Cancer Res (2012) 72 (8_Supplement): LB-181.

https://doi.org/10.1158/1538-7445.AM2012-LB-181

Published: 15 April 2012

View article titled, Abstract LB-181: Piperlongumine inhibits growth and survival of human Burkitt lymphoma by downregulating NF-κB, c-Myc and LMP1

Journal Articles

Abstract 4852: cFLIP-regulated and caspase-8-mediated limited cleavage of RIP1 promotes NF-kB activation and inhibits cell death induced by TRAIL

Hasem Habelhah, Laiqun Zhang, Siegfried Janz, Lauren Workman, Ken Blackwell

Cancer Res (2012) 72 (8_Supplement): 4852.

https://doi.org/10.1158/1538-7445.AM2012-4852

Published: 15 April 2012

View article titled, Abstract 4852: cFLIP-regulated and caspase-8-mediated limited cleavage of RIP1 promotes NF-kB activation and inhibits cell death induced by TRAIL

Journal Articles

Abstract LB-48: Cooperation of NF-κB, STAT3 and p300 on the growth and survival of plasma-cell neoplasia

Seong-Su Han, Dong-Ju Son, Kaylia Duncan, Siegfried Janz

Cancer Res (2011) 71 (8_Supplement): LB-48.

https://doi.org/10.1158/1538-7445.AM2011-LB-48

Published: 15 April 2011

View article titled, Abstract LB-48: Cooperation of NF-κB, STAT3 and p300 on the growth and survival of plasma-cell neoplasia

Journal Articles

Abstract 1181: Expression studies from the PVT1 region of 8q24

Konrad Huppi, Jason Pitt, Brady Wahlberg, Tamara L. Jones, J. Frederic Mushinski, Siegfried Janz, Natasha J. Caplen

Cancer Res (2011) 71 (8_Supplement): 1181.

https://doi.org/10.1158/1538-7445.AM2011-1181

Published: 15 April 2011

View article titled, Abstract 1181: Expression studies from the PVT1 region of 8q24

Journal Articles

Abstract 1952: The rapid generation of mouse B cell lymphomas by lentiviral mediated overexpression of miR-1204 from a genetically unstable region of human 8q24

Konrad Huppi, Brady Wahlberg, Jason Pitt, Tamara L. Jones, Kristen Gehlhaus, Mark Mackiewicz, J. Frederic Mushinski, Vishala Neppalli, Siegfried Janz, Natasha J. Caplen

Cancer Res (2010) 70 (8_Supplement): 1952.

https://doi.org/10.1158/1538-7445.AM10-1952

Published: 15 April 2010

View article titled, Abstract 1952: The rapid generation of mouse B cell lymphomas by lentiviral mediated overexpression of miR-1204 from a genetically unstable region of human 8q24

Journal Articles

Abstract 397: The antitumor activity of the investigational drug MLN9708 in genetically engineered mouse models of plasma cell malignancy

Edmund Chun Yu Lee, Michael Fitzgerald, Bret Bannerman, Jennifer Terkelsen, Ray Liu, Zhi Li, Mark Manfredi, Ling Hu, Vishala Neppalli, Brian Van Ness, Siegfried Janz

Cancer Res (2010) 70 (8_Supplement): 397.

https://doi.org/10.1158/1538-7445.AM10-397

Published: 15 April 2010

View article titled, Abstract 397: The antitumor activity of the investigational drug MLN9708 in genetically engineered mouse models of plasma cell malignancy

Journal Articles

Abstract #LB-61: Signaling crosstalk among NF-kB, STAT3 and PI3K controls the growth and survival of iMyc^E\#956; and WEHI 231 B cell lymphomas

Seong-Su Han, Van Tompkins, Hwakyung Yun, Dong-Ju Son, Siegfried Janz

Cancer Res (2009) 69 (9_Supplement): LB-61.

Published: 01 May 2009

View article titled, Abstract #LB-61: Signaling crosstalk among NF-kB, STAT3 and PI3K controls the growth and survival of iMycE\#956; and WEHI 231 B cell lymphomas

Journal Articles

Abstract #LB-114: Potential role for Tbrg1/NIAM in B-cell neoplasia

Van Tompkins, Seong-Su Han, Dawn Quelle, Siegfried Janz

Cancer Res (2009) 69 (9_Supplement): LB-114.

Published: 01 May 2009

View article titled, Abstract #LB-114: Potential role for Tbrg1/NIAM in B-cell neoplasia

Journal Articles

Growth and survival of iMyc^E^μ mouse B-lymphoma cells are dependent on NFκB, PI3K and STAT3 signaling crosstalk

Seong-Su Han, Hwakyung Yun, Siegfried Janz

Cancer Res (2008) 68 (9_Supplement): 2981.

Published: 01 May 2008

View article titled, Growth and survival of iMycEμ mouse B-lymphoma cells are dependent on NFκB, PI3K and STAT3 signaling crosstalk

Journal Articles

A Transgenic Mouse Model of Plasma Cell Malignancy Shows Phenotypic, Cytogenetic, and Gene Expression Heterogeneity Similar to Human Multiple Myeloma

Kristin L.M. Boylan, Mary A. Gosse, Sarah E. Staggs, Siegfried Janz, Suzanne Grindle, Geoffrey S. Kansas, Brian G. Van Ness

Cancer Res (2007) 67 (9): 4069–4078.

https://doi.org/10.1158/0008-5472.CAN-06-3699

Published: 04 May 2007

View article titled, A Transgenic Mouse Model of Plasma Cell Malignancy Shows Phenotypic, Cytogenetic, and Gene Expression Heterogeneity Similar to Human Multiple Myeloma

Includes: Supplementary data

Journal Articles

Plasma cell tumor (PCT) development in activation-induced cytidine deaminase (AID) deficient mice

Alexander Kovalchuk, Wendy DuBois, Elizabeth Mushinski, Carsten Hirt, Siegfried Janz, Michael Potter

Cancer Res (2007) 67 (9_Supplement): 1947.

Published: 01 May 2007

View article titled, Plasma cell tumor (PCT) development in activation-induced cytidine deaminase (AID) deficient mice

Journal Articles

Anaplastic, Plasmablastic, and Plasmacytic Plasmacytomas of Mice: Relationships to Human Plasma Cell Neoplasms and Late-Stage Differentiation of Normal B Cells

Chen-Feng Qi, Jeff X. Zhou, Chang Hoon Lee, Zohreh Naghashfar, Shao Xiang, Alexander L. Kovalchuk, Torgny N. Fredrickson, Janet W. Hartley, Derry C. Roopenian, Wendy F. Davidson, Siegfried Janz, Herbert C. Morse, III

Cancer Res (2007) 67 (6): 2439–2447.

https://doi.org/10.1158/0008-5472.CAN-06-1561

Published: 15 March 2007

View article titled, Anaplastic, Plasmablastic, and Plasmacytic Plasmacytomas of Mice: Relationships to Human Plasma Cell Neoplasms and Late-Stage Differentiation of Normal B Cells

Includes: Supplementary data

Journal Articles

Distribution of t(14;18)-positive, putative lymphoma precursor cells among B cell subsets in healthy individuals

Carsten Hirt, Gottfried Doelken, Siegfried Janz, Charles S. Rabkin

Cancer Res (2006) 66 (8_Supplement): 1075.

Published: 15 April 2006

View article titled, Distribution of t(14;18)-positive, putative lymphoma precursor cells among B cell subsets in healthy individuals

Journal Articles

PI3K/Akt signaling pathway regulates c-Myc via NFkB and GSK3b in mouse iMyc-Em B lymphoma cells

Ki-Hwan Kim, R. Eric Davis, Seung-Tae Chung, Siegfried Janz

Cancer Res (2006) 66 (8_Supplement): 912.

Published: 15 April 2006

View article titled, PI3K/Akt signaling pathway regulates c-Myc via NFkB and GSK3b in mouse iMyc-Em B lymphoma cells

Journal Articles

Global gene expression profiling clearly differentiates mouse plasma cell tumors from B-cell lymphomas but shows similarities with human multiple myelomas

Eun Sung Park, John D. Shaughnessy, Jr., Hongyang Wang, Ju-Seog Lee, Fenghuang Zhan, James D. Owens, Michael Potter, Siegfried Janz, J. Frederic Mushinski

Cancer Res (2006) 66 (8_Supplement): 60.

Published: 15 April 2006

View article titled, Global gene expression profiling clearly differentiates mouse plasma cell tumors from B-cell lymphomas but shows similarities with human multiple myelomas

Journal Articles

Insertion of Myc into Igh Accelerates Peritoneal Plasmacytomas in Mice

Sung Sup Park, Arthur L. Shaffer, Joong Su Kim, Wendy duBois, Michael Potter, Louis M. Staudt, Siegfried Janz

Cancer Res (2005) 65 (17): 7644–7652.

https://doi.org/10.1158/0008-5472.CAN-05-1222

Published: 01 September 2005

View article titled, Insertion of Myc into Igh Accelerates Peritoneal Plasmacytomas in Mice

Includes: Supplementary data

NARROW

Bruton Tyrosine Kinase Is a Therapeutic Target in Stem-like Cells from Multiple Myeloma

Abstract A8: Network analysis of retroviral and transposon mutagenesis sites in B cell lymphoma converges on MyD88 pathway

Abstract 1834: Noncoding RNAs of the 8q24 locus: Consequences of the over-expression or suppression of miR-1204 and PVT1 in developing B cells.

Abstract 1672: Population prevalence of consensus translocations in follicular and mantle cell lymphomas

Abstract LB-181: Piperlongumine inhibits growth and survival of human Burkitt lymphoma by downregulating NF-κB, c-Myc and LMP1

Abstract 4852: cFLIP-regulated and caspase-8-mediated limited cleavage of RIP1 promotes NF-kB activation and inhibits cell death induced by TRAIL

Abstract LB-48: Cooperation of NF-κB, STAT3 and p300 on the growth and survival of plasma-cell neoplasia

Abstract 1181: Expression studies from the PVT1 region of 8q24

Abstract 1952: The rapid generation of mouse B cell lymphomas by lentiviral mediated overexpression of miR-1204 from a genetically unstable region of human 8q24

Abstract 397: The antitumor activity of the investigational drug MLN9708 in genetically engineered mouse models of plasma cell malignancy

Abstract #LB-61: Signaling crosstalk among NF-kB, STAT3 and PI3K controls the growth and survival of iMyc^E\#956; and WEHI 231 B cell lymphomas

Abstract #LB-114: Potential role for Tbrg1/NIAM in B-cell neoplasia

Growth and survival of iMyc^E^μ mouse B-lymphoma cells are dependent on NFκB, PI3K and STAT3 signaling crosstalk

A Transgenic Mouse Model of Plasma Cell Malignancy Shows Phenotypic, Cytogenetic, and Gene Expression Heterogeneity Similar to Human Multiple Myeloma

Plasma cell tumor (PCT) development in activation-induced cytidine deaminase (AID) deficient mice

Anaplastic, Plasmablastic, and Plasmacytic Plasmacytomas of Mice: Relationships to Human Plasma Cell Neoplasms and Late-Stage Differentiation of Normal B Cells

Distribution of t(14;18)-positive, putative lymphoma precursor cells among B cell subsets in healthy individuals

PI3K/Akt signaling pathway regulates c-Myc via NFkB and GSK3b in mouse iMyc-Em B lymphoma cells

Global gene expression profiling clearly differentiates mouse plasma cell tumors from B-cell lymphomas but shows similarities with human multiple myelomas

Insertion of Myc into Igh Accelerates Peritoneal Plasmacytomas in Mice

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