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Shunbin Xiong
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Journal Articles

Abstract A042: Differences in gain-of-function and inhibitory effects amongst p53 mutants in vivo

Shunbin Xiong, Dhruv Chachad, Yun Zhang, Jovanka Gencel-Augusto, Mario Sirito, Vinod Pant, Peirong Yang, Chang Sun, Guillermina Lozano
Journal: Cancer Research
Cancer Res (2023) 83 (2_Supplement_2): A042.
https://doi.org/10.1158/1538-7445.METASTASIS22-A042
Published: 15 January 2023
View article titled, Abstract A042: Differences in gain-of-function and inhibitory effects amongst p53 mutants <em>in vivo</em>
Journal Articles

Differential Gain-of-Function Activity of Three p53 Hotspot Mutants In Vivo

Shunbin Xiong, Dhruv Chachad, Yun Zhang, Jovanka Gencel-Augusto, Mario Sirito, Vinod Pant, Peirong Yang, Chang Sun, Gilda Chau, Yuan Qi, Xiaoping Su, Elizabeth M. Whitley, Adel K. El-Naggar, Guillermina Lozano
Journal: Cancer Research
Cancer Res (2022) 82 (10): 1926–1936.
https://doi.org/10.1158/0008-5472.CAN-21-3376
Published: 16 May 2022
View article titled, Differential Gain-of-Function Activity of Three p53 Hotspot Mutants <em>In Vivo</em>
Open the PDF for Differential Gain-of-Function Activity of Three p53 Hotspot Mutants <em>In Vivo</em> in another window
Includes: Supplementary data
Journal Articles

Alterations of the Mdm2 C-Terminus Differentially Impact Its Function In Vivo

Vinod Pant, Neeraj K. Aryal, Shunbin Xiong, Gilda P. Chau, Natalie W. Fowlkes, Guillermina Lozano
Journal: Cancer Research
Cancer Res (2022) 82 (7): 1313–1320.
https://doi.org/10.1158/0008-5472.CAN-21-2381
Published: 01 April 2022
View article titled, Alterations of the Mdm2 C-Terminus Differentially Impact Its Function <em>In Vivo</em>
Open the PDF for Alterations of the Mdm2 C-Terminus Differentially Impact Its Function <em>In Vivo</em> in another window
Journal Articles

Abstract 2417: Mutant p53 and oncogenic KRAS converge on CREB1 to drive pancreatic cancer metastasis

Michael Paul Kim, Xinqun Li, Jenying Deng, Yun Zhang, Bingbing Dai, Kendra Allton, Tara Hughes, Christian Siangco, Jithesh Augustine, Yaan Kang, Joy M. McDaniel, Shunbin Xiong, Eugene Koay, Florencia McAllister, Christopher Bristow, Timothy Heffernan, Anirban Maitra, Bin Liu, Michelle Barton, Amanda Wasylischen, Jason Fleming, Guillermina lozano
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2417.
https://doi.org/10.1158/1538-7445.AM2021-2417
Published: 01 July 2021
View article titled, Abstract 2417: Mutant p53 and oncogenic KRAS converge on CREB1 to drive pancreatic cancer metastasis
Journal Articles

Abstract IA08: Somatic p53 mutations drive development of triple-negative breast cancer with evolutionarily distinct metastases

Yun Zhang, Shunbin Xiong, Guillermina Lozano
Journal: Cancer Research
Cancer Res (2018) 78 (10_Supplement): IA08.
https://doi.org/10.1158/1538-7445.MOUSEMODELS17-IA08
Published: 14 May 2018
View article titled, Abstract IA08: Somatic p53 mutations drive development of triple-negative breast cancer with evolutionarily distinct metastases
Journal Articles

Abstract B07: Gain of function activities of p53R245W in a conditional knock-in mouse model

Shunbin Xiong, Yun Zhang, Guillermina Lozano
Journal: Cancer Research
Cancer Res (2016) 76 (7_Supplement): B07.
https://doi.org/10.1158/1538-7445.TUMMET15-B07
Published: 26 May 2016
View article titled, Abstract B07: Gain of function activities of p53R245W in a conditional knock-in mouse model
Journal Articles

Abstract 1459: Mining for metastasis genes in osteosarcomas from p53 +/R172H mice

Shunbin Xiong, Young-Ah Suh, Alfonso Quintás-Cardama, Guillermina Lozano
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1459.
https://doi.org/10.1158/1538-7445.AM2011-1459
Published: 15 April 2011
View article titled, Abstract 1459: Mining for metastasis genes in osteosarcomas from <em>p53 <sup>+/R172H</sup></em> mice
Journal Articles

Spontaneous Tumorigenesis in Mice Overexpressing the p53-Negative Regulator Mdm4

Shunbin Xiong, Vinod Pant, Young-Ah Suh, Carolyn S. Van Pelt, Yongxing Wang, Yasmine A. Valentin-Vega, Sean M. Post, Guillermina Lozano
Journal: Cancer Research
Cancer Res (2010) 70 (18): 7148–7154.
https://doi.org/10.1158/0008-5472.CAN-10-1457
Published: 14 September 2010
View article titled, Spontaneous Tumorigenesis in Mice Overexpressing the p53-Negative Regulator Mdm4
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Includes: Supplementary data
Journal Articles

Abstract 1958: Signals activating mutant p53 in vivo

Young-Ah Suh, Sean Post, Cathalina Elizondo, Adel K. El-Naggar, Shunbin Xiong, Guillermina Lozano
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1958.
https://doi.org/10.1158/1538-7445.AM10-1958
Published: 15 April 2010
View article titled, Abstract 1958: Signals activating mutant p53 in vivo
Journal Articles

Abstract #LB-41: Identification and characteriztion of selective MDMX inhibitors

Michael Dyer, Damon Reed, Ying Shen, Anang Shelat, David Smithson, Alexander Arnold, Shunbin Xiong, Guillermina Lozano, Kiplin Guy
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): LB-41.
Published: 01 May 2009
View article titled, Abstract #LB-41: Identification and characteriztion of selective MDMX inhibitors
Journal Articles

EWS-FLI1 Induces Developmental Abnormalities and Accelerates Sarcoma Formation in a Transgenic Mouse Model

Patrick P. Lin, Manoj K. Pandey, Fenghua Jin, Shunbin Xiong, Michael Deavers, John M. Parant, Guillermina Lozano
Journal: Cancer Research
Cancer Res (2008) 68 (21): 8968–8975.
https://doi.org/10.1158/0008-5472.CAN-08-0573
Published: 30 October 2008
View article titled, EWS-FLI1 Induces Developmental Abnormalities and Accelerates Sarcoma Formation in a Transgenic Mouse Model
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Journal Articles

Arsenic trioxide-induced killing of non-small cell lung cancer and sarcoma murine cell lines is dependent on p53, but not K-RAS, mutational status

Alfonso Quintas-Cardama, Shunbin Xiong, Guillermina Lozano, Don Gibbons
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3320.
Published: 01 May 2008
View article titled, Arsenic trioxide-induced killing of non-small cell lung cancer and sarcoma murine cell lines is dependent on <em>p53</em>, but not <em>K-RAS</em>, mutational status
Journal Articles

Overexpression of Mdm4 in mouse induced spontaneous tumorgenesis

Shunbin Xiong, Carolyn Van Pelt, Catalina Elizondo-Fraire, Guillermina Lozano
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 3060.
Published: 01 May 2007
View article titled, Overexpression of Mdm4 in mouse induced spontaneous tumorgenesis
Journal Articles

Development of poorly differentiated sarcomas in a novel transgenic mouse expressing the EWS-FLI1 gene of Ewing’s sarcoma

Patrick P. Lin, Fenghua Jin, Shunbin Xiong, Brandon Greenberg, Carolyn Van Pelt, Guillermina Lozano
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 644.
Published: 15 April 2006
View article titled, Development of poorly differentiated sarcomas in a novel transgenic mouse expressing the EWS-FLI1 gene of Ewing’s sarcoma
Journal Articles

Up-Regulation of Vascular Endothelial Growth Factor in Breast Cancer Cells by the Heregulin-β1-activated p38 Signaling Pathway Enhances Endothelial Cell Migration

Shunbin Xiong, Rebecca Grijalva, Lianglin Zhang, Nina T. Nguyen, Peter W. Pisters, Raphael E. Pollock, Dihua Yu
Journal: Cancer Research
Cancer Res (2001) 61 (4): 1727–1732.
Published: 02 February 2001
View article titled, Up-Regulation of Vascular Endothelial Growth Factor in Breast Cancer Cells by the Heregulin-β1-activated p38 Signaling Pathway Enhances Endothelial Cell Migration
Open the PDF for Up-Regulation of Vascular Endothelial Growth Factor in Breast Cancer Cells by the Heregulin-β1-activated p38 Signaling Pathway Enhances Endothelial Cell Migration in another window
Journal Articles

Wild-Type p53 Suppresses Angiogenesis in Human Leiomyosarcoma and Synovial Sarcoma by Transcriptional Suppression of Vascular Endothelial Growth Factor Expression

Lianglin Zhang, Dihua Yu, Mei Hu, Shunbin Xiong, Aiqing Lang, Lee M. Ellis, Raphael E. Pollock
Journal: Cancer Research
Cancer Res (2000) 60 (13): 3655–3661.
Published: 01 July 2000
View article titled, Wild-Type <em>p53</em> Suppresses Angiogenesis in Human Leiomyosarcoma and Synovial Sarcoma by Transcriptional Suppression of Vascular Endothelial Growth Factor Expression
Open the PDF for Wild-Type <em>p53</em> Suppresses Angiogenesis in Human Leiomyosarcoma and Synovial Sarcoma by Transcriptional Suppression of Vascular Endothelial Growth Factor Expression in another window