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Journal Articles

Abstract 1083: Cell membrane-anchored and tumor-targeted IL12 T-cell therapy destroys cancer-associated fibroblasts and disrupts extracellular matrix in heterogenous osteosarcoma xenograft models

Jiemiao Hu, Alexander Lazar, Wei-Lien Wang, Wendong Zhang, Zhiliang Jia, Dristhi Ragoonanan, Jian Wang, Xueqing Xia, Kris Mahadeo, Richard Gorlick, Shulin Li
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1083.
https://doi.org/10.1158/1538-7445.AM2024-1083
Published: 22 March 2024
View article titled, Abstract 1083: Cell membrane-anchored and tumor-targeted IL12 T-cell therapy destroys cancer-associated fibroblasts and disrupts extracellular matrix in heterogenous osteosarcoma xenograft models
Journal Articles

Abstract 4102: attIL12-T cell therapy destructs cancer-associated fibroblasts and extracellular matrix in heterogenous osteosarcoma xenograft models

Jiemiao Hu, Alexander Lazar, Davis Ingram, Wei-Lien Wang, Wendong Zhang, Zhiliang Jia, Dristhi Ragoonanan, Jian Wang, Xueqing Xia, Kris Mahadeo, Richard Gorlick, Shulin Li
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4102.
https://doi.org/10.1158/1538-7445.AM2023-4102
Published: 04 April 2023
View article titled, Abstract 4102: attIL12-T cell therapy destructs cancer-associated fibroblasts and extracellular matrix in heterogenous osteosarcoma xenograft models
Journal Articles

Abstract 2544: TGF-β receptors 1 and 2 are functional biomarkers that stratify risk of hepatocellular cancer (HCC). Artificial intelligence based validation at three centers

Sobia Zaidi, Kirty Shetty, Herbert Yu, Linda Wong, Shuyun Rao, Wilma Jogunoori, Richard Amdur, Shulin Li, Patricia latham, Bao-Ngoc Nguyen, Lopa Mishra
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2544.
https://doi.org/10.1158/1538-7445.AM2021-2544
Published: 01 July 2021
View article titled, Abstract 2544: TGF-β receptors 1 and 2 are functional biomarkers that stratify risk of hepatocellular cancer (HCC). Artificial intelligence based validation at three centers
Journal Articles

Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGFβ Signaling

Jian Chen, Abhisek Mitra, Shulin Li, Shumei Song, Bao-Ngoc Nguyen, Jiun-Sheng Chen, Ji-Hyun Shin, Nancy R. Gough, Paul Lin, Vincent Obias, Aiwu Ruth He, Zhixing Yao, Tathiane M. Malta, Houtan Noushmehr, Patricia S. Latham, Xiaoping Su, Asif Rashid, Bibhuti Mishra, Ray-Chang Wu, Lopa Mishra
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (9): 1819–1832.
https://doi.org/10.1158/0008-5472.CAN-19-3116
Published: 04 May 2020
View article titled, Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGFβ Signaling
Open the PDF for Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGFβ Signaling in another window
Includes: Supplementary data
Journal Articles

Abstract 4443: Targeting E3 ligase PJA1 via TGF-β pathway in hepatocellular carcinoma

Kazufumi Ohshiro, Jian Chen, Wilma Jogunoori, Chu-Xia Deng, Bibhuti Mishra, Shulin Li, Lopa Mishra
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4443.
https://doi.org/10.1158/1538-7445.AM2019-4443
Published: 01 July 2019
View article titled, Abstract 4443: Targeting E3 ligase PJA1 via TGF-β pathway in hepatocellular carcinoma
Journal Articles

Abstract 1345: Automated capture and analysis of circulating tumor cells across different types of tumors in pediatric cancer patients

Izhar S. Batth, Wafik Zaky, Soumen Khatua, Najat C. Daw, Kris M. Mahadeo, Sajad Khazal, Aisha Albert, Wilber Huang, Diva Chen, Jonathan B. Gill, Eugenie Kleinerman, Richard Gorlick, Shulin Li
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1345.
https://doi.org/10.1158/1538-7445.AM2019-1345
Published: 01 July 2019
View article titled, Abstract 1345: Automated capture and analysis of circulating tumor cells across different types of tumors in pediatric cancer patients
Journal Articles

Abstract 3156: Pathway Specific Functional Biomarkers for the Early Detection of Liver Cancer

Kirti Shetty, Chu-Xia Deng, Wilma S. Jogunoori, Richard Amdur, Linda S. Resar, Patricia Latham, Raja Mazumder, Anelia Horvath, Bao-Ngoc Nguyen, Shulin Li, Xifeng Wu, Herbert Yu, Linda L. Wong, Jon White, Sylvia Silver, Asif Rashid, Vikas Kundra, Xin Wei Wang, Lopa Mishra
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3156.
https://doi.org/10.1158/1538-7445.AM2019-3156
Published: 01 July 2019
View article titled, Abstract 3156: Pathway Specific Functional Biomarkers for the Early Detection of Liver Cancer
Journal Articles

Abstract 1196: Induction of NKG2D ligand expression by CD8+ T cells through a nuclear factor-kappa B and P300/CBP-associated factor-dependent mechanism

Jiemiao Hu, Xueqing Xia, Shulin Li
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1196.
https://doi.org/10.1158/1538-7445.AM2019-1196
Published: 01 July 2019
View article titled, Abstract 1196: Induction of NKG2D ligand expression by CD8<sup>+</sup> T cells through a nuclear factor-kappa B and P300/CBP-associated factor-dependent mechanism
Journal Articles

Abstract 3413: A pan-cancer atlas of genomic, epigenomic and transcriptomic alterations in the TGF-β pathway

Anil Korkut, Sobia Zaidi, Rupa Kanchi, Ashton C. Berger, Gordon Robertson, Lawrence N. Kwong, Mike Datto, Jason Roszik, Shiyun Ling, Andre Schultz, Visweswaran Ravikumar, Ganiraju Manyam, Arvind Rao, Simon Shelley, Yuexin Liu, Zhenlin Ju, Donna Hansel, Guillermo de Velasco, Arjun Pennathur, Jesper B. Andersen, Colm J. O'Rourke, Kazufumi Ohshiro, Wilma Jogunoori, Nancy Gough, Shulin Li, Hatice Osmanbeyoglu, Andres Houseman, Shuyun Rao, Maciej Wiznerowicz, Jian Chen, Shoujun Gu, Wencai Ma, Jiexin Zhang, Pan Tong, Andrew D. Cherniack, Chuxia Deng, Linda Resar-Smith, Jaffer Ajani, The Cancer Genome Atlas Research Network, John N. Weinstein, Lopa Mishra, Rehan Akbani
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3413.
https://doi.org/10.1158/1538-7445.AM2018-3413
Published: 01 July 2018
View article titled, Abstract 3413: A pan-cancer atlas of genomic, epigenomic and transcriptomic alterations in the TGF-β pathway
Journal Articles

Abstract 1107: Cell-surface vimentin-positive macrophages like CTCs as novel biomarkers of metastatic gastrointestinal stromal tumors

Heming Li, Qing H. Meng, Hyangsoon Noh, Neeta Somaiah, Keila E. Torres, Xueqing Xia, Izhar Singh Batth, Cissimol P. Joseph, Zachary A. Mulder, Ruoyu Wang, Shulin Li
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1107.
https://doi.org/10.1158/1538-7445.AM2018-1107
Published: 01 July 2018
View article titled, Abstract 1107: Cell-surface vimentin-positive macrophages like CTCs as novel biomarkers of metastatic gastrointestinal stromal tumors
Journal Articles

Abstract 2623: CHP-IL12 combined with surgery suppresses tumor metastasis and prolongs survival

Qingnan Zhao, Jiemiao Hu, Jeffry J. Cutrera, Abhisek Mitra, Xueqing Xia, Shulin Li
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2623.
https://doi.org/10.1158/1538-7445.AM2018-2623
Published: 01 July 2018
View article titled, Abstract 2623: CHP-IL12 combined with surgery suppresses tumor metastasis and prolongs survival
Journal Articles

Abstract 2626: Combination of chemotherapy and cytokine facilitates adoptive transferred effector T cells homing to the core of metastatic tumors

Jiemiao Hu, Qingnan Zhao, Xueqing Xia, Richard Gorlick, Shulin Li
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2626.
https://doi.org/10.1158/1538-7445.AM2018-2626
Published: 01 July 2018
View article titled, Abstract 2626: Combination of chemotherapy and cytokine facilitates adoptive transferred effector T cells homing to the core of metastatic tumors
Journal Articles

Abstract 5459: Regulation of IGF2 by TGF-β signaling in liver cancers and stem cell homeostasis

Shuyun Rao, Sobia Zaidi, Kazufumi Ohshiro, Jian Chen, Shoujun Gu, Wilma Jogunoori, Jon White, Bibhuti Mishra, Shulin Li, Rehan Akbani, Lopa Mishra
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5459.
https://doi.org/10.1158/1538-7445.AM2018-5459
Published: 01 July 2018
View article titled, Abstract 5459: Regulation of IGF2 by TGF-β signaling in liver cancers and stem cell homeostasis
Journal Articles

Abstract 5746: CRISPR9-mediated FGL2-KO in tumor cells impairs tumor progression in brain and triggers antitumor immune memory systematically via NF-κB dependent Batf3 expression in DCs

Jun Yan, Qingnan Zhao, Konrad Gabrusiewicz, Ling-Yuan Kong, Longfei Huo, Xueqing Xia, Jun Wei, Jingda Xu, Eric Davis, Amy B. Heimberger, Shulin Li
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5746.
https://doi.org/10.1158/1538-7445.AM2018-5746
Published: 01 July 2018
View article titled, Abstract 5746: CRISPR9-mediated FGL2-KO in tumor cells impairs tumor progression in brain and triggers antitumor immune memory systematically via NF-<em>κ</em>B dependent Batf3 expression in DCs
Journal Articles

Abstract 3869: Cell surface vimentin targeted mAb 86C increases sensitivity to temozolomide mediated cell death in glioma stem cells

Hyangsoon Noh, Jun Yan, Konrad Gabrusiewicz, Shulin Li
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3869.
https://doi.org/10.1158/1538-7445.AM2017-3869
Published: 01 July 2017
View article titled, Abstract 3869: Cell surface vimentin targeted mAb 86C increases sensitivity to temozolomide mediated cell death in glioma stem cells
Journal Articles

Abstract 1931: The first circulating tumor cell detection technique from frozen PBMCs

Heming Li, Izhar Singh Batth, Xueqing Xia, Frank J. Hsu, Neeta Somaiah, Keila Enitt Torres, Ruoyu Wang, Shulin Li
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1931.
https://doi.org/10.1158/1538-7445.AM2017-1931
Published: 01 July 2017
View article titled, Abstract 1931: The first circulating tumor cell detection technique from frozen PBMCs
Journal Articles

Abstract 1941: Cell surface vimentin is a novel marker for CTC detection in neuroblastoma

Izhar S. Batth, Heming Li, Giselle Saulnier Sholler, Shulin Li
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1941.
https://doi.org/10.1158/1538-7445.AM2017-1941
Published: 01 July 2017
View article titled, Abstract 1941: Cell surface vimentin is a novel marker for CTC detection in neuroblastoma
Journal Articles

Abstract 5330: Targeting hepatocellular carcinoma through TGF-β pathway E3 ligases

Shuyun Rao, Heather Levin, Jian Chen, Rehan Akbani, Jon White, Wilma Jogunoori, Shoujun Gu, Kazufumi Ohshiro, Sobia Zaidi, Bibhuti Mishra, Asif Rashid, Shulin Li, Lopa Mishra
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5330.
https://doi.org/10.1158/1538-7445.AM2017-5330
Published: 01 July 2017
View article titled, Abstract 5330: Targeting hepatocellular carcinoma through TGF-β pathway E3 ligases
Journal Articles

Abstract 5606: Fibrinogen-like protein 2 drives malignant tumor progression in glioma

Khatri Latha, Jun Yan, Yuhui Yang, Loyola V. Gressot, Lingyuan Kong, Ganiraju Manyam, Ravesanker Ezhilarasan, Qianghu Wang, Erik P. Sulman, Jingda Xu, Richard E. Davis, Suyun Huang, Gregory N. Fuller, Arvind Rao, Amy B. Heimberger, Shulin Li, Ganesh Rao
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5606.
https://doi.org/10.1158/1538-7445.AM2017-5606
Published: 01 July 2017
View article titled, Abstract 5606: Fibrinogen-like protein 2 drives malignant tumor progression in glioma
Journal Articles

Abstract 1569: IL6 mediated inflammatory loop reprograms normal to highly metastatic cancer stem cells at pre-HCC liver in β2SP+/- mice

Abhisek Mitra, Xueqing Xia, Lopa Mishra, Shulin Li
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1569.
https://doi.org/10.1158/1538-7445.AM2016-1569
Published: 15 July 2016
View article titled, Abstract 1569: IL6 mediated inflammatory loop reprograms normal to highly metastatic cancer stem cells at pre-HCC liver in β2SP+/- mice