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Shuk-Mei Ho
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Journal Articles

Abstract 3011: The loss of an orphan nuclear receptor NR2E3 augments Wnt/β-Catenin signaling via epigenetic dysregulation that links to the Sp1-β catenin-p300 interactions in hepatocellular carcinoma

Yuet-Kin Leung, Sung-Gwon Lee, Jiang Wang, Shuk-Mei Ho, Nancy Rusch, Chungoo Park, Kyounghyun Kim
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3011.
https://doi.org/10.1158/1538-7445.AM2024-3011
Published: 22 March 2024
View article titled, Abstract 3011: The loss of an orphan nuclear receptor NR2E3 augments Wnt/β-Catenin signaling via epigenetic dysregulation that links to the Sp1-β catenin-p300 interactions in hepatocellular carcinoma
Journal Articles

Abstract 6282: Novel androgen related gene network in prostate cancer cell model

Alex L. McDonald, Spencer Snow, Shuk-mei Ho, Yuet-kin Leung
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6282.
https://doi.org/10.1158/1538-7445.AM2024-6282
Published: 22 March 2024
View article titled, Abstract 6282: Novel androgen related gene network in prostate cancer cell model
Journal Articles

Abstract 4826: Maternal high butter fat intake heightens mammary cancer risk in offsprings gestationally exposed to bisphenol A at environmentally relevant dose

Yuet-Kin Leung, Vinothini Govindarajah, Ana Cheong, Dan Song, Xuegong Zhu, Jun Ying, Ady Kendler, Mario Medvedovic, Scott Belcher, Shuk-Mei Ho
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4826.
https://doi.org/10.1158/1538-7445.AM2017-4826
Published: 01 July 2017
View article titled, Abstract 4826: Maternal high butter fat intake heightens mammary cancer risk in offsprings gestationally exposed to bisphenol A at environmentally relevant dose
Journal Articles

Abstract 2537: MicroRNA targeting anti-apoptotic and G2/M pathways as therapeutic targets for castration resistant prostate cancer

Pheruza Tarapore, Sarah To, Bin Ouyang, Yuet-Kin Leung, Ana Cheong, Shuk-mei Ho
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2537.
https://doi.org/10.1158/1538-7445.AM2017-2537
Published: 01 July 2017
View article titled, Abstract 2537: MicroRNA targeting anti-apoptotic and G2/M pathways as therapeutic targets for castration resistant prostate cancer
Journal Articles

Abstract SY40-04: Reprogramming of the epigenome by MLL links early life environmental exposures to adult cancer risk

Quan Wang, Lindsey Trevino, Gail Prins, Maarten Bosland, Shuk-Mei Ho, Mario Medvedovic, Cheryl Lyn Walker
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): SY40-04.
https://doi.org/10.1158/1538-7445.AM2015-SY40-04
Published: 01 August 2015
View article titled, Abstract SY40-04: Reprogramming of the epigenome by MLL links early life environmental exposures to adult cancer risk
Journal Articles

Abstract 1382: Developmental exposure to BPA increases the prostate cancer susceptibility via reprogramming of androgen-responsive genes via increased H3K4me3 methylation

Quan Wang, Rebecca Lee Yean Wong, Donna F. Kusewitt, Maarten C. Bosland, Jing Chen, Mario Medvedovic, Gail S. Prins, Kurunthachalam Kannan, Shuk-Mei Ho, Cheryl Lyn Walker
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1382.
https://doi.org/10.1158/1538-7445.AM2014-1382
Published: 01 October 2014
View article titled, Abstract 1382: Developmental exposure to BPA increases the prostate cancer susceptibility via reprogramming of androgen-responsive genes via increased H3K4me3 methylation
Journal Articles

Abstract B48: Integrin α6 S-nitrosylation induces prostate cancer cell migration by loss of adhesion to laminin-1

Jared Isaac, Ying Wai Lam, Pheruza Tarapore, Shuk-mei Ho
Journal: Cancer Research
Cancer Res (2012) 72 (4_Supplement): B48.
https://doi.org/10.1158/1538-7445.PRCA2012-B48
Published: 09 May 2013
View article titled, Abstract B48: Integrin α6 S-nitrosylation induces prostate cancer cell migration by loss of adhesion to laminin-1
Journal Articles

Abstract LB-179: Enhanced resistance to tamoxifen by the c-ABL proto-oncogene in breast cancer

Hua Jun Zhao, Fu Ou-Yang, I-Fen Chen, Ming-Feng Hou, Shyng-Shiou F. Yuan, Hsueh-Ling Chang, Yi-Chen Lee, Rina Plattner, Susan Waltz, Shuk-Mei Ho, Jonathan Sims, Shao-Chun Wang
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): LB-179.
https://doi.org/10.1158/1538-7445.AM10-LB-179
Published: 15 April 2010
View article titled, Abstract LB-179: Enhanced resistance to tamoxifen by the c-ABL proto-oncogene in breast cancer
Journal Articles

Abstract LB-403: Levels of nitric oxide and prostate cancer development in healthy US men enrolled in the Health Professionals Follow-up Study

Tianying Wu, Yushan Wang, Shuk-Mei Ho, Edward Giovannucci
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): LB-403.
https://doi.org/10.1158/1538-7445.AM10-LB-403
Published: 15 April 2010
View article titled, Abstract LB-403: Levels of nitric oxide and prostate cancer development in healthy US men enrolled in the Health Professionals Follow-up Study
Journal Articles

Abstract 2797: Measurement of GST-P1 methylation in body fluids and prostate cancer diagnosis: a meta-analysis

Tianying Wu, Edward Giovannucci, Jeff Welge, Palash Mallick, Grace LeMasters, Wan-yee Tang, Shuk-Mei Ho
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2797.
https://doi.org/10.1158/1538-7445.AM10-2797
Published: 15 April 2010
View article titled, Abstract 2797: Measurement of GST-P1 methylation in body fluids and prostate cancer diagnosis: a meta-analysis
Journal Articles

Abstract 4423: Novel therapeutic potential in targeting the microtubules by nanoparticle albumin-bound paclitaxel in hepatocellular carcinoma

Qian Zhou, Arthur K-K Ching, Wilson K-C Leung, Carol Szeto, Shuk-Mei Ho, Chris C. Holmes, Yun-fei Yuan, Paul B-S Lai, Winnie Yeo, Nathalie Wong
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4423.
https://doi.org/10.1158/1538-7445.AM10-4423
Published: 15 April 2010
View article titled, Abstract 4423: Novel therapeutic potential in targeting the microtubules by nanoparticle albumin-bound paclitaxel in hepatocellular carcinoma
Journal Articles

Abstract #55: Ribosome-inactivating proteins isolated from dietary bitter melon induce apoptosis and inhibit histone deacetylase-1 selectively in premalignant and malignant prostate cancer cells

Xin Hua Liu, SuDao Xiong, Li Hui Yin, Alexander Kirschenbaum, Shen Yao, Goutham Narla, Analisa DiFeo, Kang Yu, Jian Bo Wu, Yong Yuan, Shuk-Mei Ho, Ying Wai Lam, Alice Levine
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 55.
Published: 01 May 2009
View article titled, Abstract #55: Ribosome-inactivating proteins isolated from dietary bitter melon induce apoptosis and inhibit histone deacetylase-1 selectively in premalignant and malignant prostate cancer cells
Journal Articles

Bisphenol A demethylated rat PDE4D4 promoter via alteration of expression levels of demethylases

Wan-Yee Tang, Jennifer Barker, Gail Prins, Shuk-mei Ho
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3.
Published: 01 May 2008
View article titled, Bisphenol A demethylated rat PDE4D4 promoter via alteration of expression levels of demethylases
Journal Articles

Epigenetic changes related to prenatal PAH exposure

Julie Herbstman, Shuk-Mei Ho, Wan-yee Tang, Deliang Tang, Frederica Perera
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 547.
Published: 01 May 2008
View article titled, Epigenetic changes related to prenatal PAH exposure
Journal Articles

Human β-Defensin-1, a Potential Chromosome 8p Tumor Suppressor: Control of Transcription and Induction of Apoptosis in Renal Cell Carcinoma

Carrie Q. Sun, Rebecca Arnold, Carina Fernandez-Golarz, Amanda B. Parrish, Tara Almekinder, Ju He, Shuk-mei Ho, Pavel Svoboda, Jan Pohl, Fray F. Marshall, John A. Petros
Journal: Cancer Research
Cancer Res (2006) 66 (17): 8542–8549.
https://doi.org/10.1158/0008-5472.CAN-06-0294
Published: 01 September 2006
View article titled, Human β-Defensin-1, a Potential Chromosome 8p Tumor Suppressor: Control of Transcription and Induction of Apoptosis in Renal Cell Carcinoma
Open the PDF for Human β-Defensin-1, a Potential Chromosome 8p Tumor Suppressor: Control of Transcription and Induction of Apoptosis in Renal Cell Carcinoma in another window
Journal Articles

Developmental Exposure to Estradiol and Bisphenol A Increases Susceptibility to Prostate Carcinogenesis and Epigenetically Regulates Phosphodiesterase Type 4 Variant 4

Shuk-Mei Ho, Wan-Yee Tang, Jessica Belmonte de Frausto, Gail S. Prins
Journal: Cancer Research
Cancer Res (2006) 66 (11): 5624–5632.
https://doi.org/10.1158/0008-5472.CAN-06-0516
Published: 01 June 2006
View article titled, Developmental Exposure to Estradiol and Bisphenol A Increases Susceptibility to Prostate Carcinogenesis and Epigenetically Regulates Phosphodiesterase Type 4 Variant 4
Open the PDF for Developmental Exposure to Estradiol and Bisphenol A Increases Susceptibility to Prostate Carcinogenesis and Epigenetically Regulates Phosphodiesterase Type 4 Variant 4 in another window
Includes: Supplementary data
Journal Articles

Neonatal exposure to estradiols or bisphenol A epigenetically alters phosphodiesterase type IV variant 4 (PDE4D4) and increases susceptibility to adult-induced prostate carcinogenesis

Wan-Yee Tang, Gail S. Prins, Jessica Belmonte, Shuk-Mei Ho
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 448.
Published: 15 April 2006
View article titled, Neonatal exposure to estradiols or bisphenol A epigenetically alters <em>phosphodiesterase type IV variant 4 (PDE4D4)</em> and increases susceptibility to adult-induced prostate carcinogenesis
Journal Articles

Deletion hotspots in AMACR promoter CpG island are the cis-regulatory elements and the prognostic markers during colon cancer development

Xiang Zhang, Irwin Leav, Robert Cheng, Qin Liu, Shuk-Mei Ho
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 698.
Published: 15 April 2006
View article titled, Deletion hotspots in AMACR promoter CpG island are the c<em>is</em>-regulatory elements and the prognostic markers during colon cancer development
Journal Articles

Overexpression of Cytochrome P450 1A1 and Its Novel Spliced Variant in Ovarian Cancer Cells: Alternative Subcellular Enzyme Compartmentation May Contribute to Carcinogenesis

Yuet-Kin Leung, Kin-Mang Lau, James Mobley, Zhong Jiang, Shuk-Mei Ho
Journal: Cancer Research
Cancer Res (2005) 65 (9): 3726–3734.
https://doi.org/10.1158/0008-5472.CAN-04-3771
Published: 02 May 2005
View article titled, Overexpression of <em>Cytochrome P450 1A1</em> and Its Novel Spliced Variant in Ovarian Cancer Cells: Alternative Subcellular Enzyme Compartmentation May Contribute to Carcinogenesis
Open the PDF for Overexpression of <em>Cytochrome P450 1A1</em> and Its Novel Spliced Variant in Ovarian Cancer Cells: Alternative Subcellular Enzyme Compartmentation May Contribute to Carcinogenesis in another window
Journal Articles

Cis-regulatory elements in estrogen receptor beta 0N promoter are hotspots of DNA hypermethylation during prostate cancer progression

Xiang Zhang, Yuet-Kin Leung, Shuk-Mei Ho
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1071–1072.
Published: 01 May 2005
View article titled, <em>Cis</em>-regulatory elements in estrogen receptor beta 0N promoter are hotspots of DNA hypermethylation during prostate cancer progression