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Journal Articles

Abstract 465: The preclinical characterization of TST003, a first-in-class mAb targeting gremlin-1 overexpressed by cancer-associated fibroblasts and tumor cells

Di Sun, Huanhuan Guo, Chaping Cheng, Hongjun Li, Xinlai Yao, Shuang Lu, Jie Ding, Shenjie Zhang, Shijie Zhou, Steven Yu, Yi Gu, Xueming Qian
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 465.
https://doi.org/10.1158/1538-7445.AM2023-465
Published: 04 April 2023
View article titled, Abstract 465: The preclinical characterization of TST003, a first-in-class mAb targeting gremlin-1 overexpressed by cancer-associated fibroblasts and tumor cells
Journal Articles

Abstract C037: KMT2D loss in pancreatic cancer cells leads to an immunosuppressive tumor microenvironment by upregulating the interferon and inflammatory response pathways

Hong S. Kim, Jing Yang, Shuang Lu, Marina Pasca di Magliano, Kai Ge, Jiaqi Shi
Journal: Cancer Research
Cancer Res (2022) 82 (22_Supplement): C037.
https://doi.org/10.1158/1538-7445.PANCA22-C037
Published: 15 November 2022
View article titled, Abstract C037: KMT2D loss in pancreatic cancer cells leads to an immunosuppressive tumor microenvironment by upregulating the interferon and inflammatory response pathways
Journal Articles

Abstract 6013: TST005, a bifunctional fusion protein of PD-L1/TGF-βRII, demonstrates potent anti-tumor activities with good safety profiles

Huanhuan Guo, Xinlai Yao, Chunming Wang, Linlin Mao, Hongjun Li, Shuang Lu, Di Sun, Chengwei Jiang, Shenjie Zhang, Lisa Zheng, Fan Zhang, Fei Teng, Steven Yu, Yi Gu, Xueming Qian
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6013.
https://doi.org/10.1158/1538-7445.AM2022-6013
Published: 15 June 2022
View article titled, Abstract 6013: TST005, a bifunctional fusion protein of PD-L1/TGF-βRII, demonstrates potent anti-tumor activities with good safety profiles
Journal Articles

Abstract C22: Loss of KDM6A promotes pancreatic cancer progression by upregulating epithelial-mesenchymal transition pathway

Sivakumar Jeyarajan, Zhujun Yi, Shanqiao Wei, Shuang Lu, Hong Kim, Michelle Paulsen, Karan Bedi, Mats Ljungman, Jiaqi Shi
Journal: Cancer Research
Cancer Res (2019) 79 (24_Supplement): C22.
https://doi.org/10.1158/1538-7445.PANCA19-C22
Published: 13 December 2019
View article titled, Abstract C22: Loss of KDM6A promotes pancreatic cancer progression by upregulating epithelial-mesenchymal transition pathway
Journal Articles

Abstract C28: KMT2D mediates TGF-β-induced epithelial-to-mesenchymal transition to promote more aggressive pancreatic cancer

Hong S. Kim, Shuang Lu, Yubo Cao, Zhujun Yi, Sivakumar Jeyarajan, Lili Zhao, Karan Bedi, Ishwarya V. Narayanan, Michelle T. Paulsen, Mats Ljungman, Jiaqi Shi
Journal: Cancer Research
Cancer Res (2019) 79 (24_Supplement): C28.
https://doi.org/10.1158/1538-7445.PANCA19-C28
Published: 13 December 2019
View article titled, Abstract C28: KMT2D mediates TGF-β-induced epithelial-to-mesenchymal transition to promote more aggressive pancreatic cancer
Journal Articles

Abstract 5333: Monoubiquitination inhibits the actin bundling activity of fascin

Shengchen Lin, Shuang Lu, Mentor Mulaj, Bin Fang, Tyler Keeley, Lixin Wan, Jihui Hao, Martin Muschol, Jianwei Sun, Shengyu Yang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5333.
https://doi.org/10.1158/1538-7445.AM2017-5333
Published: 01 July 2017
View article titled, Abstract 5333: Monoubiquitination inhibits the actin bundling activity of fascin