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Shoshana Yakar
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Journal Articles

Abstract 5081: The IGF axis regulates hepatic stellate cell recruitment and activation during colorectal carcinoma liver metastasis

Maria C. Fernandez, Roni F. Rayes, Jun Xu, Tatiana Kisseleva, Shoshana Yakar, Pnina Brodt
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5081.
https://doi.org/10.1158/1538-7445.AM2015-5081
Published: 01 August 2015
View article titled, Abstract 5081: The IGF axis regulates hepatic stellate cell recruitment and activation during colorectal carcinoma liver metastasis
Journal Articles

Insulin-Mediated Acceleration of Breast Cancer Development and Progression in a Nonobese Model of Type 2 Diabetes

Ruslan Novosyadlyy, Danielle E. Lann, Archana Vijayakumar, Anne Rowzee, Deborah A. Lazzarino, Yvonne Fierz, Joan M. Carboni, Marco M. Gottardis, Patricia A. Pennisi, Alfredo A. Molinolo, Naamit Kurshan, Wilson Mejia, Stefania Santopietro, Shoshana Yakar, Teresa L. Wood, Derek LeRoith
Journal: Cancer Research
Cancer Res (2010) 70 (2): 741–751.
https://doi.org/10.1158/0008-5472.CAN-09-2141
Published: 13 January 2010
View article titled, Insulin-Mediated Acceleration of Breast Cancer Development and Progression in a Nonobese Model of Type 2 Diabetes
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Includes: Supplementary data
Journal Articles

Insulin-Like Growth Factor-I Regulates the Liver Microenvironment in Obese Mice and Promotes Liver Metastasis

Yingjie Wu, Pnina Brodt, Hui Sun, Wilson Mejia, Ruslan Novosyadlyy, Nomeli Nunez, Xiaoli Chen, Arnulfo Mendoza, Sung-Hyeok Hong, Chand Khanna, Shoshana Yakar
Journal: Cancer Research
Cancer Res (2010) 70 (1): 57–67.
https://doi.org/10.1158/0008-5472.CAN-09-2472
Published: 04 January 2010
View article titled, Insulin-Like Growth Factor-I Regulates the Liver Microenvironment in Obese Mice and Promotes Liver Metastasis
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Includes: Supplementary data
Journal Articles

Reduced Susceptibility to Two-Stage Skin Carcinogenesis in Mice with Low Circulating Insulin-Like Growth Factor I Levels

Tricia Moore, Steve Carbajal, Linda Beltran, Susan N. Perkins, Shoshana Yakar, Derek LeRoith, Stephen D. Hursting, John DiGiovanni
Journal: Cancer Research
Cancer Res (2008) 68 (10): 3680–3688.
https://doi.org/10.1158/0008-5472.CAN-07-6271
Published: 15 May 2008
View article titled, Reduced Susceptibility to Two-Stage Skin Carcinogenesis in Mice with Low Circulating Insulin-Like Growth Factor I Levels
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Journal Articles

Targeted Deletion of Hepatic Igf1 in TRAMP Mice Leads to Dramatic Alterations in the Circulating Insulin-Like Growth Factor Axis but Does Not Reduce Tumor Progression

Makoto Anzo, Laura J. Cobb, David L. Hwang, Hemal Mehta, Jonathan W. Said, Shoshana Yakar, Derek LeRoith, Pinchas Cohen
Journal: Cancer Research
Cancer Res (2008) 68 (9): 3342–3349.
https://doi.org/10.1158/0008-5472.CAN-07-3165
Published: 01 May 2008
View article titled, Targeted Deletion of Hepatic <em>Igf1</em> in TRAMP Mice Leads to Dramatic Alterations in the Circulating Insulin-Like Growth Factor Axis but Does Not Reduce Tumor Progression
Open the PDF for Targeted Deletion of Hepatic <em>Igf1</em> in TRAMP Mice Leads to Dramatic Alterations in the Circulating Insulin-Like Growth Factor Axis but Does Not Reduce Tumor Progression in another window
Journal Articles

Genetic reduction of circulating insulin-like growth factor (IGF)-1 inhibits obesity -promoted colon tumorigenesis in mice

Susan Olivo-Marston, Stephen Hursting, Jackie Lavigne, Rami Maarouf, Shoshana Yakar, Curtis Harris
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1605.
Published: 01 May 2008
View article titled, Genetic reduction of circulating insulin-like growth factor (IGF)-1 inhibits obesity -promoted colon tumorigenesis in mice
Journal Articles

Absence of the Full-Length Breast Cancer–Associated Gene-1 Leads to Increased Expression of Insulin-Like Growth Factor Signaling Axis Members

Vivek Shukla, Xavier Coumoul, Liu Cao, Rui-Hong Wang, Cuiying Xiao, Xiaoling Xu, Sebastiano Andò, Shoshana Yakar, Derek LeRoith, Chuxia Deng
Journal: Cancer Research
Cancer Res (2006) 66 (14): 7151–7157.
https://doi.org/10.1158/0008-5472.CAN-05-4570
Published: 18 July 2006
View article titled, Absence of the Full-Length Breast Cancer–Associated Gene-1 Leads to Increased Expression of Insulin-Like Growth Factor Signaling Axis Members
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Includes: Supplementary data
Journal Articles

The role of host derived insulin-like growth factor I on murine osteosarcoma metastasis

Sung-Hyeok Hong, Rachel Newman, Karen Hoffman, Arnulfo Mendoza, Shoshana Yakar, Derek Leroith, Lee Helman, Chand Khanna
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 70.
Published: 15 April 2006
View article titled, The role of host derived insulin-like growth factor I on murine osteosarcoma metastasis
Journal Articles

IGF-I deficiency protects obese mice from accelerated tumor growth

Shoshana Yakar, Nomeli Nunez, Pnina Brodt, Hui Sun, Stephen D. Hursting
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 856.
Published: 15 April 2006
View article titled, IGF-I deficiency protects obese mice from accelerated tumor growth
Journal Articles

Overexpression of the Tumor Suppressor Gene Phosphatase and Tensin Homologue Partially Inhibits Wnt-1–Induced Mammary Tumorigenesis

Hong Zhao, Yongzhi Cui, Joelle Dupont, Hui Sun, Lothar Hennighausen, Shoshana Yakar
Journal: Cancer Research
Cancer Res (2005) 65 (15): 6864–6873.
https://doi.org/10.1158/0008-5472.CAN-05-0181
Published: 01 August 2005
View article titled, Overexpression of the Tumor Suppressor Gene Phosphatase and Tensin Homologue Partially Inhibits Wnt-1–Induced Mammary Tumorigenesis
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Journal Articles

C/EBPβ is essential for survival of myeloid tumor cells

Jennifer L. Wessells, Shoshana Yakar, Peter Johnson
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1190.
Published: 01 April 2004
View article titled, C/EBPβ is essential for survival of myeloid tumor cells
Journal Articles

Reduced Circulating Insulin-like Growth Factor I Levels Delay the Onset of Chemically and Genetically Induced Mammary Tumors

Yiping Wu, Karen Cui, Keiko Miyoshi, Lothar Hennighausen, Jeffrey E. Green, Jennifer Setser, Derek LeRoith, Shoshana Yakar
Journal: Cancer Research
Cancer Res (2003) 63 (15): 4384–4388.
Published: 07 August 2003
View article titled, Reduced Circulating Insulin-like Growth Factor I Levels Delay the Onset of Chemically and Genetically Induced Mammary Tumors
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Journal Articles

Circulating Insulin-like Growth Factor-I Levels Regulate Colon Cancer Growth and Metastasis

Yiping Wu, Shoshana Yakar, Ling Zhao, Lothar Hennighausen, Derek LeRoith
Journal: Cancer Research
Cancer Res (2002) 62 (4): 1030–1035.
Published: 01 February 2002
View article titled, Circulating Insulin-like Growth Factor-I Levels Regulate Colon Cancer Growth and Metastasis
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