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Journal Articles

Abstract PO3-19-02: White Button Mushroom and Biomarkers of Immune Cell and Inflammatory Responses in Obese Postmenopausal Women at High Risk of Breast Cancer

Jessica Dzubnar, Lisa Yee, Shiuan Chen
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO3-19-02.
https://doi.org/10.1158/1538-7445.SABCS23-PO3-19-02
Published: 02 May 2024
View articletitled, Abstract PO3-19-02: White Button Mushroom and Biomarkers of Immune Cell and Inflammatory Responses in Obese Postmenopausal Women at High Risk of Breast Cancer
Journal Articles

Abstract 1831: Reduction of PMN-MDSC level/activity following the consumption of white button mushroom in prostate cancer murine models and patients: A translational study to mitigate cancer progression

Xiaoqiang Wang, Shoubao Ma, Przemyslaw Twardowski, Clayton Lau, Yin Chan, Kelly Wong, Jinhui Wang, Xiwei Wu, Paul Frankel, Timothy G. Wilson, Timothy W. Synold, Cary Presant, Jianhua Yu, Shiuan Chen
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1831.
https://doi.org/10.1158/1538-7445.AM2024-1831
Published: 22 March 2024
View articletitled, Abstract 1831: Reduction of PMN-MDSC level/activity following the consumption of white button mushroom in prostate cancer murine models and patients: A translational study to mitigate cancer progression
Journal Articles

Abstract P3-11-05: Efficacy of Gonadal steroids on aromatase inhibitor-resistant ER+ breast cancer: Insights from single-cell trajectory analysis of a patient-derived xenograft model

Hitomi Mori, Kohei Saeki, Gregory Chang, Jinhui Wang, Xiwei Wu, Noriko Kanaya, George Somlo, Shiuan Chen
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P3-11-05.
https://doi.org/10.1158/1538-7445.SABCS22-P3-11-05
Published: 01 March 2023
View articletitled, Abstract P3-11-05: Efficacy of Gonadal steroids on aromatase inhibitor-resistant ER+ breast cancer: Insights from single-cell trajectory analysis of a patient-derived xenograft model
Journal Articles

Abstract OT2-19-01: Presurgical treatment with ribociclib and letrozole in patients with locally advanced breast cancer: The NEOLETRIB study

Xavier Tekpli, Shom Goel, Barbro Holm, Lars-Egil Fallang, Laurens Cornelus Reitsma, Stephanie Beate Geisler, Hilde Presterud Ødegård, Cathrine Bergquist Fosskaug, Ida Caroline Lindem, Manouchehr Seyedzadeh, Jonn Terje Geitung, Joana Reis, Kjell Inge Gjesdal, Unn-Cathrin Buvarp, Marie Loeng, Kristine Kleivi Sahlberg, Alina Carmen Porojnicu, Helle Kristine Skjerven, Andliena Tahiri, Shakila Jabeen, Torben Lüders, Vahid Bemanian, Jørgen Jahnsen, Marianne Lyngra, Antoni Hurtado, Jason Carroll, Shiuan Chen, Vessela Kristensen, Jürgen Geisler
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): OT2-19-01.
https://doi.org/10.1158/1538-7445.SABCS21-OT2-19-01
Published: 15 February 2022
View articletitled, Abstract OT2-19-01: Presurgical treatment with ribociclib and letrozole in patients with locally advanced breast cancer: The NEOLETRIB study
Journal Articles

Abstract PD1-04: Estrogen-mediated mechanisms in estrogen receptor-positive breast cancer at the single cell level

Hitomi Mori, Kohei Saeki, Gregory Chang, Jinhui Wang, Xiwei Wu, Pei-Yin Hsu, Noriko Kanaya, George Somlo, Masafumi Nakamura, Andrea Bild, Shiuan Chen
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): PD1-04.
https://doi.org/10.1158/1538-7445.SABCS21-PD1-04
Published: 15 February 2022
View articletitled, Abstract PD1-04: Estrogen-mediated mechanisms in estrogen receptor-positive breast cancer at the single cell level
Journal Articles

Abstract 2106: Combined deacetylase and bromodomain inhibition downregulates ERCC2 and suppresses growth of metastatic colon cancer cells

Sabeeta Kapoor, Trace Gustafson, Mutian Zhang, Ying-Shiuan Chen, Jia Li, Nhung Nguyen, Jorge Enrique Perez, Wan Mohaiza Dashwood, Praveen Rajendran, Roderick Dashwood
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2106.
https://doi.org/10.1158/1538-7445.AM2021-2106
Published: 01 July 2021
View articletitled, Abstract 2106: Combined deacetylase and bromodomain inhibition downregulates ERCC2 and suppresses growth of metastatic colon cancer cells
Journal Articles

Abstract PD7-02: Estrogen-induced cell cycle arrest as an unexpected outcome of aromatase inhibitor-resistance: Insights from single-cell trajectory analysis of a patient-derived xenograft model

Hitomi Mori, Kohei Saeki, Gregory Chang, Xiwei Wu, Pei-Yin Hsu, Noriko Kanaya, George Somlo, Shiuan Chen
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PD7-02.
https://doi.org/10.1158/1538-7445.SABCS20-PD7-02
Published: 15 February 2021
View articletitled, Abstract PD7-02: Estrogen-induced cell cycle arrest as an unexpected outcome of aromatase inhibitor-resistance: Insights from single-cell trajectory analysis of a patient-derived xenograft model
Journal Articles

Abstract P1-08-01: Estrogen-induced cell cycle arrest and apoptosis in aromatase inhibitor-resistant breast cancer: Insights from single cells analysis of a patient-derived xenograft model

Hitomi Mori, Kohei Saeki, Gregory Chang, Xiwei Wu, Pei-Yin Hsu, Noriko Kanaya, George Somlo, Shiuan Chen
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P1-08-01.
https://doi.org/10.1158/1538-7445.SABCS19-P1-08-01
Published: 15 February 2020
View articletitled, Abstract P1-08-01: Estrogen-induced cell cycle arrest and apoptosis in aromatase inhibitor-resistant breast cancer: Insights from single cells analysis of a patient-derived xenograft model
Journal Articles

Abstract 2614: CCAR2 acetylation establishes a BET/BRD9 acetyl switch in response to combined deacetylase and bromodomain inhibition

Gavin S. Johnson, Praveen Rajendran, Li Li, Ying-Shiuan Chen, W. Mohaiza Dashwood, Nhung Nguyen, Ahmet M. Ulusan, Furkan Ertem, Mutian Zhang, Deqiang Sun, Yun Huang, Shan Wang, Hon-Chiu E. Leung, David Lieberman, Laura M. Beaver, Emily Ho, Mark T. Bedford, Kyle Chang, Eduardo Vilar, Roderick H. Dashwood
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2614.
https://doi.org/10.1158/1538-7445.AM2019-2614
Published: 01 July 2019
View articletitled, Abstract 2614: CCAR2 acetylation establishes a BET/BRD9 acetyl switch in response to combined deacetylase and bromodomain inhibition
Journal Articles

Acetylation of CCAR2 Establishes a BET/BRD9 Acetyl Switch in Response to Combined Deacetylase and Bromodomain Inhibition

Praveen Rajendran, Gavin Johnson, Li Li, Ying-Shiuan Chen, Mohaiza Dashwood, Nhung Nguyen, Ahmet Ulusan, Furkan Ertem, Mutian Zhang, Jia Li, Deqiang Sun, Yun Huang, Shan Wang, Hon-Chiu Leung, David Lieberman, Laura Beaver, Emily Ho, Mark Bedford, Kyle Chang, Eduardo Vilar, Roderick Dashwood
Journal: Cancer Research
Cancer Res (2019) 79 (5): 918–927.
https://doi.org/10.1158/0008-5472.CAN-18-2003
Published: 01 March 2019
View articletitled, Acetylation of CCAR2 Establishes a BET/BRD9 Acetyl Switch in Response to Combined Deacetylase and Bromodomain Inhibition
Open the PDF for Acetylation of CCAR2 Establishes a BET/BRD9 Acetyl Switch in Response to Combined Deacetylase and Bromodomain Inhibition in another window
Includes: Supplementary data
Journal Articles

Abstract 4428: A miRNA signature linked to human environmental risk defined from carcinogen-induced and genetically-driven colon carcinogenesis models

Ying-Shiuan Chen, Rong Wang, Wan-Mohaiza Dashwood, Christiane Löhr, David E. Williams, Emily Ho, Susanne Mertens-Talcott, Roderick H. Dashwood
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4428.
https://doi.org/10.1158/1538-7445.AM2017-4428
Published: 01 July 2017
View articletitled, Abstract 4428: A miRNA signature linked to human environmental risk defined from carcinogen-induced and genetically-driven colon carcinogenesis models
Journal Articles

Abstract P6-11-09: A preclinical study to demonstrate the utility of fulvestrant and MLN0128 combination against HR+ and HER2+ breast cancer

Shang Victoria Wu, Hannah Lu, Masaya Kai, Noriko Kanaya, Thenhang Luu, Courtney Vito, Laura Kruper, Joanne Mortimer, Shiuan Chen
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P6-11-09.
https://doi.org/10.1158/1538-7445.SABCS14-P6-11-09
Published: 01 May 2015
View articletitled, Abstract P6-11-09: A preclinical study to demonstrate the utility of fulvestrant and MLN0128 combination against HR+ and HER2+ breast cancer
Journal Articles

CCL2 Mediates Cross-talk between Cancer Cells and Stromal Fibroblasts That Regulates Breast Cancer Stem Cells

Akihiro Tsuyada, Amy Chow, Jun Wu, George Somlo, Peiguo Chu, Sofia Loera, Thehang Luu, Arthur Xuejun Li, Xiwei Wu, Wei Ye, Shiuan Chen, Weiying Zhou, Yang Yu, Yuan-Zhong Wang, Xiubao Ren, Hui Li, Peggy Scherle, Yukio Kuroki, Shizhen Emily Wang
Journal: Cancer Research
Cancer Res (2012) 72 (11): 2768–2779.
https://doi.org/10.1158/0008-5472.CAN-11-3567
Published: 31 May 2012
View articletitled, CCL2 Mediates Cross-talk between Cancer Cells and Stromal Fibroblasts That Regulates Breast Cancer Stem Cells
Open the PDF for CCL2 Mediates Cross-talk between Cancer Cells and Stromal Fibroblasts That Regulates Breast Cancer Stem Cells in another window
Includes: Supplementary data
Journal Articles

Blueberry Phytochemicals Inhibit Growth and Metastatic Potential of MDA-MB-231 Breast Cancer Cells through Modulation of the Phosphatidylinositol 3-Kinase Pathway

Lynn S. Adams, Sheryl Phung, Natalie Yee, Navindra P. Seeram, Liya Li, Shiuan Chen
Journal: Cancer Research
Cancer Res (2010) 70 (9): 3594–3605.
https://doi.org/10.1158/0008-5472.CAN-09-3565
Published: 28 April 2010
View articletitled, Blueberry Phytochemicals Inhibit Growth and Metastatic Potential of MDA-MB-231 Breast Cancer Cells through Modulation of the Phosphatidylinositol 3-Kinase Pathway
Open the PDF for Blueberry Phytochemicals Inhibit Growth and Metastatic Potential of MDA-MB-231 Breast Cancer Cells through Modulation of the Phosphatidylinositol 3-Kinase Pathway in another window
Journal Articles

Abstract 606: Heat shock protein 90 inhibitors: New mode of therapy to overcome aromatase inhibitor resistance

Cynthie Wong, Shiuan Chen
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 606.
https://doi.org/10.1158/1538-7445.AM10-606
Published: 15 April 2010
View articletitled, Abstract 606: Heat shock protein 90 inhibitors: New mode of therapy to overcome aromatase inhibitor resistance
Journal Articles

Abstract 605: Intermittent treatment of hormone-dependent breast cancer using exemestane: Translational research from lab bench to bedside

Y. Wang, S. Phung, S. Masri, D. Zhou, J. Geisler, P. Lonning, C. Chung, G. Somlo, Shiuan Chen
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 605.
https://doi.org/10.1158/1538-7445.AM10-605
Published: 15 April 2010
View articletitled, Abstract 605: Intermittent treatment of hormone-dependent breast cancer using exemestane: Translational research from lab bench to bedside
Journal Articles

Heat Shock Protein 90 Inhibitors: New Mode of Therapy to Overcome Endocrine Resistance

Cynthie Wong, Shiuan Chen
Journal: Cancer Research
Cancer Res (2009) 69 (22): 8670–8677.
https://doi.org/10.1158/0008-5472.CAN-09-1259
Published: 11 November 2009
View articletitled, Heat Shock Protein 90 Inhibitors: New Mode of Therapy to Overcome Endocrine Resistance
Open the PDF for Heat Shock Protein 90 Inhibitors: New Mode of Therapy to Overcome Endocrine Resistance in another window
Includes: Supplementary data
Journal Articles

Abstract #3575: Dietary administration of the licorice flavonoid isoliquiritigenin deters growth of MCF-7 cells overexpressing aromatase

Ye Lan, Wai M Gho, Franky L Chan, Shiuan Chen, Lai K Leung
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3575.
Published: 01 May 2009
View articletitled, Abstract #3575: Dietary administration of the licorice flavonoid isoliquiritigenin deters growth of MCF-7 cells overexpressing aromatase
Journal Articles

Abstract #3001: A phase I prevention trial of grape seed extract as a natural aromatase inhibitor in h ealthy post-menopausal women at risk for breast cancer

Melanie Palomares, Natalie Perdomo, Sheryl Phung, Frank Stanczyk, Timothy Synold, Paul Frankel, Shiuan Chen
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3001.
Published: 01 May 2009
View articletitled, Abstract #3001: A phase I prevention trial of grape seed extract as a natural aromatase inhibitor in h ealthy post-menopausal women at risk for breast cancer
Journal Articles

Genome-Wide Analysis of Aromatase Inhibitor-Resistant, Tamoxifen-Resistant, and Long-Term Estrogen-Deprived Cells Reveals a Role for Estrogen Receptor

Selma Masri, Sheryl Phung, Xin Wang, Xiwei Wu, Yate-Ching Yuan, Lawrence Wagman, Shiuan Chen
Journal: Cancer Research
Cancer Res (2008) 68 (12): 4910–4918.
https://doi.org/10.1158/0008-5472.CAN-08-0303
Published: 16 June 2008
View articletitled, Genome-Wide Analysis of Aromatase Inhibitor-Resistant, Tamoxifen-Resistant, and Long-Term Estrogen-Deprived Cells Reveals a Role for Estrogen Receptor
Open the PDF for Genome-Wide Analysis of Aromatase Inhibitor-Resistant, Tamoxifen-Resistant, and Long-Term Estrogen-Deprived Cells Reveals a Role for Estrogen Receptor in another window
Includes: Supplementary data