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Journal Articles

Abstract 1384: Stearoyl-CoA desaturase confers cell density-dependent resistance to ferroptosis induced by inhibition of glutathione peroxidase 4 in melanoma cells

Hitomi Shirahama, Yuri Tani, Satomi Tsukahara, Yuka Okamoto, Akiko Hasebe, Shingo Dan, Akihiro Tomida

Cancer Res (2023) 83 (7_Supplement): 1384.

https://doi.org/10.1158/1538-7445.AM2023-1384

Published: 04 April 2023

View articletitled, Abstract 1384: Stearoyl-CoA desaturase confers cell density-dependent resistance to ferroptosis induced by inhibition of glutathione peroxidase 4 in melanoma cells

Journal Articles

Abstract 384: Identification of a lung adenocarcinoma cell line addicted to ERBB4, an actionable target for cancer therapy

Noritaka Tanaka, Kanami Yamazaki, Yuko Uno, Yoshimi Ohashi, Yumiko Nishimura, Masaaki Sawa, Shingo Dan

Cancer Res (2019) 79 (13_Supplement): 384.

https://doi.org/10.1158/1538-7445.AM2019-384

Published: 01 July 2019

View articletitled, Abstract 384: Identification of a lung adenocarcinoma cell line addicted to ERBB4, an actionable target for cancer therapy

Journal Articles

Abstract 1299: Potential antitumor effects of a Golgi disrupting agent, M-COPA, via targeting cell-extracellular matrix interaction under the spheroid culture conditions

Yoshimi Ohashi, Kazuma Takeuchi, Mutsumi Okamura, Akinobu Akatsuka, Isamu Shiina, Kentaro Yoshimatsu, Shingo Dan

Cancer Res (2019) 79 (13_Supplement): 1299.

https://doi.org/10.1158/1538-7445.AM2019-1299

Published: 01 July 2019

View articletitled, Abstract 1299: Potential antitumor effects of a Golgi disrupting agent, M-COPA, via targeting cell-extracellular matrix interaction under the spheroid culture conditions

Journal Articles

Abstract 3909: Potential antitumor effect of a pan-PI3K inhibitor ZSTK474 on human sarcoma cell lines

Shingo Dan, Naomi Tamaki, Nachi Namatame, Yuya Yoshizawa, Mutsumi Okamura, Yumiko Nishimura, Kanami Yamazaki, Shin-ichi Yaguchi

Cancer Res (2019) 79 (13_Supplement): 3909.

https://doi.org/10.1158/1538-7445.AM2019-3909

Published: 01 July 2019

View articletitled, Abstract 3909: Potential antitumor effect of a pan-PI3K inhibitor ZSTK474 on human sarcoma cell lines

Journal Articles

M-COPA, a Golgi Disruptor, Inhibits Cell Surface Expression of MET Protein and Exhibits Antitumor Activity against MET-Addicted Gastric Cancers

Yoshimi Ohashi, Mutsumi Okamura, Asaka Hirosawa, Naomi Tamaki, Akinobu Akatsuka, Kuo-Ming Wu, Hyeong-Wook Choi, Kentaro Yoshimatsu, Isamu Shiina, Takao Yamori, Shingo Dan

Cancer Res (2016) 76 (13): 3895–3903.

https://doi.org/10.1158/0008-5472.CAN-15-2220

Published: 30 June 2016

View articletitled, M-COPA, a Golgi Disruptor, Inhibits Cell Surface Expression of MET Protein and Exhibits Antitumor Activity against MET-Addicted Gastric Cancers

Includes: Supplementary data

Journal Articles

Abstract 4450: Identification of IGF1R as a responsible factor and a therapeutic target for overcoming acquired and intrinsic resistance to PI3K inhibitors.

Shingo Dan, Sho Isoyama, Yumiko Nishimura, Naoki Nakamura, Gensei Kajiwara, Naomi Tamaki, Mutsumi Okamura, Takao Yamori

Cancer Res (2013) 73 (8_Supplement): 4450.

https://doi.org/10.1158/1538-7445.AM2013-4450

Published: 15 April 2013

View articletitled, Abstract 4450: Identification of IGF1R as a responsible factor and a therapeutic target for overcoming acquired and intrinsic resistance to PI3K inhibitors.

Journal Articles

Abstract LB-357: Identification of a new inhibitor of the Golgi system, targeting ADP-ribosylation Factor 1 (Arf1) with potential for cancer therapy

Yoshimi Ohashi, Hiroshi Iijima, Noriyuki Yamaotsu, Kanami Yamazaki, Shigeo Sato, Mutsumi Okamura, Kenji Sugimoto, Shingo Dan, Shuichi Hirono, Takao Yamori

Cancer Res (2012) 72 (8_Supplement): LB-357.

https://doi.org/10.1158/1538-7445.AM2012-LB-357

Published: 15 April 2012

View articletitled, Abstract LB-357: Identification of a new inhibitor of the Golgi system, targeting ADP-ribosylation Factor 1 (Arf1) with potential for cancer therapy

Journal Articles

Abstract 2655: Visualization of G1 arrest of cell cycle induced by inhibition of PI-3 kinase in cancer cells: in vitro evaluations

Yumiko Mukai, Shingo Dan, Mutsumi Okamura, Yasumichi Inoue, Aki Hanyu, Asako Sakaue-Sawano, Takeshi Imamura, Atsushi Miyawaki, Takao Yamori

Cancer Res (2011) 71 (8_Supplement): 2655.

https://doi.org/10.1158/1538-7445.AM2011-2655

Published: 15 April 2011

View articletitled, Abstract 2655: Visualization of G1 arrest of cell cycle induced by inhibition of PI-3 kinase in cancer cells: in vitro evaluations

Journal Articles

Abstract 4399: In vitro and in vivo evaluations of correlation between the activation status of signaling pathways and the efficacy of anticancer compounds in a panel of JFCR39 human cancer cell lines

Shingo Dan, Mutsumi Okamura, Mariko Seki, Kanami Yamazaki, Yumiko Mukai, Takao Yamori

Cancer Res (2011) 71 (8_Supplement): 4399.

https://doi.org/10.1158/1538-7445.AM2011-4399

Published: 15 April 2011

View articletitled, Abstract 4399: In vitro and in vivo evaluations of correlation between the activation status of signaling pathways and the efficacy of anticancer compounds in a panel of JFCR39 human cancer cell lines

Journal Articles

Correlating Phosphatidylinositol 3-Kinase Inhibitor Efficacy with Signaling Pathway Status: In silico and Biological Evaluations

Shingo Dan, Mutsumi Okamura, Mariko Seki, Kanami Yamazaki, Hironobu Sugita, Michiyo Okui, Yumiko Mukai, Hiroyuki Nishimura, Reimi Asaka, Kimie Nomura, Yuichi Ishikawa, Takao Yamori

Cancer Res (2010) 70 (12): 4982–4994.

https://doi.org/10.1158/0008-5472.CAN-09-4172

Published: 14 June 2010

View articletitled, Correlating Phosphatidylinositol 3-Kinase Inhibitor Efficacy with Signaling Pathway Status: In silico and Biological Evaluations

Includes: Supplementary data

Journal Articles

Abstract 2493: Inhibition of phosphoinositide 3-kinase suppressed growth of cancer cells with PIK3CA mutations or loss of PTEN expression via G₀/G₁ arrest of cell cycle but not apoptosis

Shingo Dan, Mutsumi Okamura, Hisashi Yoshimi, Yumiko Mukai, Kanami Yamazaki, Yasumichi Inoue, Aki Hanyu, Takeshi Imamura, Asako Sakaue-Sawano, Atsushi Miyawaki, Takao Yamori

Cancer Res (2010) 70 (8_Supplement): 2493.

https://doi.org/10.1158/1538-7445.AM10-2493

Published: 15 April 2010

View articletitled, Abstract 2493: Inhibition of phosphoinositide 3-kinase suppressed growth of cancer cells with PIK3CA mutations or loss of PTEN expression via G0/G1 arrest of cell cycle but not apoptosis

Journal Articles

Abstract #LB-214: Efficacy of PI3K inhibitors to PI3K mutants in enzyme and cell levels

Shingo Dan, Hironobu Sugita, Kanami Yamazaki, Takao Yamori

Cancer Res (2009) 69 (9_Supplement): LB-214.

Published: 01 May 2009

View articletitled, Abstract #LB-214: Efficacy of PI3K inhibitors to PI3K mutants in enzyme and cell levels

Journal Articles

ZSTK474, a novel PI3K inhibitor, down-regulates CDC25A and induces G1 phase cell cycle arrest in human cancer cells

Shingo Dan, Yumiko Mukai, Shin-ichi Yaguchi, Takao Yamori

Cancer Res (2008) 68 (9_Supplement): 664.

Published: 01 May 2008

View articletitled, ZSTK474, a novel PI3K inhibitor, down-regulates CDC25A and induces G1 phase cell cycle arrest in human cancer cells

Journal Articles

Ectopic expression of PIK3CD in human cancer cell lines and human lung carcinoma

Hiroyuki Nakamura, Shingo Dan, Tetsuyuki Akashi, Michiyo Okui, Shinichi Egawa, Yuichi Ishikawa, Michiaki Unno, Takao Yamori

Cancer Res (2007) 67 (9_Supplement): LB-18.

Published: 01 May 2007

View articletitled, Ectopic expression of PIK3CD in human cancer cell lines and human lung carcinoma

Journal Articles

Disruption of SFN gene expression potentiates topotecan efficacy in p53-mutant human gastric cancer cell lines

Shingo Dan, Yumiko Mukai, Takao Yamori

Cancer Res (2005) 65 (9_Supplement): 546.

Published: 01 May 2005

View articletitled, Disruption of SFN gene expression potentiates topotecan efficacy in p53-mutant human gastric cancer cell lines

Journal Articles

Overexpression of cyclin B1 is associated with the enhancement of paclitaxcel-sensitivity in human gastric cancer cell lines

Yoko Yoshida, Kanami Yamazaki, Noriyuki Nakatsu, Shingo Dan, Shigeo Sato, Takashi Tsuruo, Takao Yamori

Cancer Res (2005) 65 (9_Supplement): 551.

Published: 01 May 2005

View articletitled, Overexpression of cyclin B1 is associated with the enhancement of paclitaxcel-sensitivity in human gastric cancer cell lines

Journal Articles

An Integrated Database of Chemosensitivity to 55 Anticancer Drugs and Gene Expression Profiles of 39 Human Cancer Cell Lines

Shingo Dan, Tatsuhiko Tsunoda, Osamu Kitahara, Rempei Yanagawa, Hitoshi Zembutsu, Toyomasa Katagiri, Kanami Yamazaki, Yusuke Nakamura, Takao Yamori

Cancer Res (2002) 62 (4): 1139–1147.

Published: 01 February 2002

View articletitled, An Integrated Database of Chemosensitivity to 55 Anticancer Drugs and Gene Expression Profiles of 39 Human Cancer Cell Lines

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Abstract 1384: Stearoyl-CoA desaturase confers cell density-dependent resistance to ferroptosis induced by inhibition of glutathione peroxidase 4 in melanoma cells

Abstract 384: Identification of a lung adenocarcinoma cell line addicted to ERBB4, an actionable target for cancer therapy

Abstract 1299: Potential antitumor effects of a Golgi disrupting agent, M-COPA, via targeting cell-extracellular matrix interaction under the spheroid culture conditions

Abstract 3909: Potential antitumor effect of a pan-PI3K inhibitor ZSTK474 on human sarcoma cell lines

M-COPA, a Golgi Disruptor, Inhibits Cell Surface Expression of MET Protein and Exhibits Antitumor Activity against MET-Addicted Gastric Cancers

Abstract 4450: Identification of IGF1R as a responsible factor and a therapeutic target for overcoming acquired and intrinsic resistance to PI3K inhibitors.

Abstract LB-357: Identification of a new inhibitor of the Golgi system, targeting ADP-ribosylation Factor 1 (Arf1) with potential for cancer therapy

Abstract 2655: Visualization of G1 arrest of cell cycle induced by inhibition of PI-3 kinase in cancer cells: in vitro evaluations

Abstract 4399: In vitro and in vivo evaluations of correlation between the activation status of signaling pathways and the efficacy of anticancer compounds in a panel of JFCR39 human cancer cell lines

Correlating Phosphatidylinositol 3-Kinase Inhibitor Efficacy with Signaling Pathway Status: In silico and Biological Evaluations

Abstract 2493: Inhibition of phosphoinositide 3-kinase suppressed growth of cancer cells with PIK3CA mutations or loss of PTEN expression via G₀/G₁ arrest of cell cycle but not apoptosis

Abstract #LB-214: Efficacy of PI3K inhibitors to PI3K mutants in enzyme and cell levels

ZSTK474, a novel PI3K inhibitor, down-regulates CDC25A and induces G1 phase cell cycle arrest in human cancer cells

Ectopic expression of PIK3CD in human cancer cell lines and human lung carcinoma

Disruption of SFN gene expression potentiates topotecan efficacy in p53-mutant human gastric cancer cell lines

Overexpression of cyclin B1 is associated with the enhancement of paclitaxcel-sensitivity in human gastric cancer cell lines

An Integrated Database of Chemosensitivity to 55 Anticancer Drugs and Gene Expression Profiles of 39 Human Cancer Cell Lines

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