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Shin-ichi Hayashi
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Journal Articles

Abstract PD2-04: Different mechanism of CDK4/6 inhibitor resistance between ribociclib and abemaciclib

Masafumi Iida, Daichi Toyosawa, Misato Nakamura, Emi Tokuda, Toshifumi Niwa, Ryuichi Yoshida, Takanori Ishida, Shin-ichi Hayashi
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): PD2-04.
https://doi.org/10.1158/1538-7445.SABCS19-PD2-04
Published: 15 February 2020
View article titled, Abstract PD2-04: Different mechanism of CDK4/6 inhibitor resistance between ribociclib and abemaciclib
Journal Articles

Abstract P6-04-26: PI3K inhibitors restored the sensitivity to anti-estrogen drugs in endocrine therapy resistant cell lines

Emi Tokuda, Shunta Sasaki, Kouki Tsuboi, Masafumi Iida, Toshifumi Niwa, Shigehira Saji, Shin-Ichi Hayashi
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P6-04-26.
https://doi.org/10.1158/1538-7445.SABCS19-P6-04-26
Published: 15 February 2020
View article titled, Abstract P6-04-26: PI3K inhibitors restored the sensitivity to anti-estrogen drugs in endocrine therapy resistant cell lines
Journal Articles

Abstract 5243: Prognostic value of nuclear and non-nuclear estrogen receptor expression by immunohistochemistry with phosphor-integrated dots in hormone receptor-positive early breast cancer

Zhaorong Guo, Hiroshi Tada, Narufumi Kitamura, Yoh Hamada, Shin-ichi Hayashi, Noriaki Ohuchi, Kosuke Gonda, Takanori Ishida
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5243.
https://doi.org/10.1158/1538-7445.AM2018-5243
Published: 01 July 2018
View article titled, Abstract 5243: Prognostic value of nuclear and non-nuclear estrogen receptor expression by immunohistochemistry with phosphor-integrated dots in hormone receptor-positive early breast cancer
Journal Articles

Abstract P3-05-25: Efficacy of everolimus on multiple mechanisms of AI-resistance in vitro and xenograft, and characterization of their everolimus-resistance

Mariko Kimura, Natsu Fujiki, Toru Hanamura, Toshifumi Niwa, Yuri Yamaguchi, Takashi Ishikawa, Itaru Endo, Shin-ichi Hayashi
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P3-05-25.
https://doi.org/10.1158/1538-7445.SABCS14-P3-05-25
Published: 01 May 2015
View article titled, Abstract P3-05-25: Efficacy of everolimus on multiple mechanisms of AI-resistance in vitro and xenograft, and characterization of their everolimus-resistance
Journal Articles

Abstract 4754: Androgen receptor acquires an oncogenic role in the AI resistance mechanism in breast cancer

Rika Fujii, Toru Hanamura, Toshifumi Niwa, Yuri Yamaguchi, Takanori Ishida, Hironobu Sasano, Noriaki Ohuchi, Shin-ichi Hayashi
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4754.
https://doi.org/10.1158/1538-7445.AM2014-4754
Published: 01 October 2014
View article titled, Abstract 4754: Androgen receptor acquires an oncogenic role in the AI resistance mechanism in breast cancer
Journal Articles

Abstract 2110: Molecular characterization of everolimus-resistant cell lines established from estrogen depletion-resistant MCF-7

Mariko Kimura, Toru Hanamura, Toshifumi Niwa, Yuri Yamaguchi, Itaru Endo, Shin-ichi Hayashi
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2110.
https://doi.org/10.1158/1538-7445.AM2014-2110
Published: 01 October 2014
View article titled, Abstract 2110: Molecular characterization of everolimus-resistant cell lines established from estrogen depletion-resistant MCF-7
Journal Articles

Abstract 1313: The androgen metabolite-dependent growth of hormone receptor-positive breast cancer as a possible aromatase inhibitor resistance mechanism.

Toru Hanamura, Toshifumi Niwa, Sayo Nishikawa, Hiromi Konno, Tatsuyuki Gohno, Chika Chika Tazawa, Yasuhito Kobayashi, Masafumi Kurosumi, Hiroyuki Takei, Yuri Yamaguchi, Ken-ichi Ken-ichi Ito, Shin-ichi Hayashi
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1313.
https://doi.org/10.1158/1538-7445.AM2013-1313
Published: 15 April 2013
View article titled, Abstract 1313: The androgen metabolite-dependent growth of hormone receptor-positive breast cancer as a possible aromatase inhibitor resistance mechanism.
Journal Articles

Association of Estrogen Receptor α and Histone Deacetylase 6 Causes Rapid Deacetylation of Tubulin in Breast Cancer Cells

Kotaro Azuma, Tomohiko Urano, Kuniko Horie-Inoue, Shin-ichi Hayashi, Ryuichi Sakai, Yasuyoshi Ouchi, Satoshi Inoue
Journal: Cancer Research
Cancer Res (2009) 69 (7): 2935–2940.
https://doi.org/10.1158/0008-5472.CAN-08-3458
Published: 01 April 2009
View article titled, Association of Estrogen Receptor α and Histone Deacetylase 6 Causes Rapid Deacetylation of Tubulin in Breast Cancer Cells
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Journal Articles

Aromatase Localization in Human Breast Cancer Tissues: Possible Interactions between Intratumoral Stromal and Parenchymal Cells

Yasuhiro Miki, Takashi Suzuki, Chika Tazawa, Yuri Yamaguchi, Kunio Kitada, Seijiro Honma, Takuya Moriya, Hisashi Hirakawa, Dean B. Evans, Shin-ichi Hayashi, Noriaki Ohuchi, Hironobu Sasano
Journal: Cancer Research
Cancer Res (2007) 67 (8): 3945–3954.
https://doi.org/10.1158/0008-5472.CAN-06-3105
Published: 17 April 2007
View article titled, Aromatase Localization in Human Breast Cancer Tissues: Possible Interactions between Intratumoral Stromal and Parenchymal Cells
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Journal Articles

Differential effects of ERbeta and ERbetacx transfection and ERbeta agonists on proliferation of MCF7 cells

Guojun Cheng, Yoko Omoto, Shin-Ichi Hayashi, Margaret Warner, Jan-Åke Gustafsson
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 858.
Published: 15 April 2006
View article titled, Differential effects of ERbeta and ERbetacx transfection and ERbeta agonists on proliferation of MCF7 cells
Journal Articles

Progesterone Receptor in Non–Small Cell Lung Cancer—A Potent Prognostic Factor and Possible Target for Endocrine Therapy

Hironori Ishibashi, Takashi Suzuki, Satoshi Suzuki, Hiromichi Niikawa, Liangying Lu, Yasuhiro Miki, Takuya Moriya, Shin-ichi Hayashi, Masashi Handa, Takashi Kondo, Hironobu Sasano
Journal: Cancer Research
Cancer Res (2005) 65 (14): 6450–6458.
https://doi.org/10.1158/0008-5472.CAN-04-3087
Published: 15 July 2005
View article titled, Progesterone Receptor in Non–Small Cell Lung Cancer—A Potent Prognostic Factor and Possible Target for Endocrine Therapy
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Journal Articles

Tumor-Stromal Interaction through the Estrogen-Signaling Pathway in Human Breast Cancer

Yuri Yamaguchi, Hiroyuki Takei, Kimito Suemasu, Yasuhito Kobayashi, Masafumi Kurosumi, Nobuhiro Harada, Shin-ichi Hayashi
Journal: Cancer Research
Cancer Res (2005) 65 (11): 4653–4662.
https://doi.org/10.1158/0008-5472.CAN-04-3236
Published: 01 June 2005
View article titled, Tumor-Stromal Interaction through the Estrogen-Signaling Pathway in Human Breast Cancer
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Journal Articles

Expression of Estrogen Receptor (ER) βcx Protein in ERα-positive Breast Cancer: Specific Correlation with Progesterone Receptor

Shigehira Saji, Yoko Omoto, Chikako Shimizu, Margaret Warner, Yukiko Hayashi, Shin-ichiro Horiguchi, Toru Watanabe, Shin-ichi Hayashi, Jan-Åke Gustafsson, Masakazu Toi
Journal: Cancer Research
Cancer Res (2002) 62 (17): 4849–4853.
Published: 01 September 2002
View article titled, Expression of Estrogen Receptor (ER) βcx Protein in ERα-positive Breast Cancer: <subtitle>Specific Correlation with Progesterone Receptor</subtitle>
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Journal Articles

Prognostic Value of Genetically Diagnosed Lymph Node Micrometastasis in Non-Small Cell Lung Carcinoma Cases

Takehisa Hashimoto, Yasuhito Kobayashi, Yuichi Ishikawa, Shigehiro Tsuchiya, Sakae Okumura, Ken Nakagawa, Yoshio Tokuchi, Moriaki Hayashi, Kazunori Nishida, Shin-ichi Hayashi, Jun-ichi Hayashi, Eiju Tsuchiya
Journal: Cancer Research
Cancer Res (2000) 60 (22): 6472–6478.
Published: 15 November 2000
View article titled, Prognostic Value of Genetically Diagnosed Lymph Node Micrometastasis in Non-Small Cell Lung Carcinoma Cases
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Journal Articles

p53 Null Mutations Undetected by Immunohistochemical Staining Predict a Poor Outcome with Early-Stage Non-Small Cell Lung Carcinomas

Takehisa Hashimoto, Yoshio Tokuchi, Moriaki Hayashi, Yasuhito Kobayashi, Kazunori Nishida, Shin-ichi Hayashi, Yuichi Ishikawa, Shigehiro Tsuchiya, Ken Nakagawa, Jun-ichi Hayashi, Eiju Tsuchiya
Journal: Cancer Research
Cancer Res (1999) 59 (21): 5572–5577.
Published: 01 November 1999
View article titled, <em>p53</em> Null Mutations Undetected by Immunohistochemical Staining Predict a Poor Outcome with Early-Stage Non-Small Cell Lung Carcinomas
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Journal Articles

Abnormal FHIT Transcripts in Human Breast Carcinomas: A Clinicopathological and Epidemiological Analysis of 61 Japanese Cases

Shin-ichi Hayashi, Keiji Tanimoto, Kyoko Hajiro-Nakanishi, Eijyu Tsuchiya, Masafumi Kurosumi, Yasuhiro Higashi, Kazue Imai, Kenji Suga, Kei Nakachi
Journal: Cancer Research
Cancer Res (1997) 57 (10): 1981–1985.
Published: 01 May 1997
View article titled, Abnormal FHIT Transcripts in Human Breast Carcinomas: A Clinicopathological and Epidemiological Analysis of 61 Japanese Cases
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Journal Articles

Polymorphisms of the CYP1A1 and Glutathione S-Transferase Genes Associated with Susceptibility to Lung Cancer in Relation to Cigarette Dose in a Japanese Population

Kei Nakachi, Kazue Imai, Shin-ichi Hayashi, Kaname Kawajiri
Journal: Cancer Research
Cancer Res (1993) 53 (13): 2994–2999.
Published: 01 July 1993
View article titled, Polymorphisms of the <em>CYP1A1</em> and Glutathione <em>S</em>-Transferase Genes Associated with Susceptibility to Lung Cancer in Relation to Cigarette Dose in a Japanese Population
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Journal Articles

Genetic Susceptibility to Squamous Cell Carcinoma of the Lung in Relation to Cigarette Smoking Dose

Kei Nakachi, Kazue Imai, Shin-ichi Hayashi, Junko Watanabe, Kaname Kawajiri
Journal: Cancer Research
Cancer Res (1991) 51 (19): 5177–5180.
Published: 01 October 1991
View article titled, Genetic Susceptibility to Squamous Cell Carcinoma of the Lung in Relation to Cigarette Smoking Dose
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Journal Articles

Purification and Characterization of Cytochrome P-450 Induced by Benz(a)anthracene in Mouse Skin Microsomes

Takeshi Ichikawa, Shin-ichi Hayashi, Mitsuhide Noshiro, Kazuaki Takada, Kyuichiro Okuda
Journal: Cancer Research
Cancer Res (1989) 49 (4): 806–809.
Published: 01 February 1989
View article titled, Purification and Characterization of Cytochrome P-450 Induced by Benz(<em>a</em>)anthracene in Mouse Skin Microsomes
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