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Shin-ichi Akiyama
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Journal Articles

Abstract 1442: Novel linkage of thymidine catabolism and the glycolytic pathway in human cancer cells

Sho Tabata, Masatatsu Yamamoto, Hisatsugu Goto, Yasuhiko Nishioka, Masaru Tomita, Tomoyoshi Soga, Tatsuhiko Furukawa, Shin-ichi Akiyama
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1442.
https://doi.org/10.1158/1538-7445.AM2018-1442
Published: 01 July 2018
View article titled, Abstract 1442: Novel linkage of thymidine catabolism and the glycolytic pathway in human cancer cells
Journal Articles

Abstract 3487: Molecular basis for induction of IL-8 expression by thymidine phosphorylase

Shin-ichi Akiyama
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3487.
https://doi.org/10.1158/1538-7445.AM2011-3487
Published: 15 April 2011
View article titled, Abstract 3487: Molecular basis for induction of IL-8 expression by thymidine phosphorylase
Journal Articles

Abstract 3607: The effect of gefitinib on the expression of c-MYC and TSP-1 in cancer cells

Mitsuhiro Suenaga, Chuwa Tei, Shin-ichi Akiyama
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3607.
https://doi.org/10.1158/1538-7445.AM10-3607
Published: 15 April 2010
View article titled, Abstract 3607: The effect of gefitinib on the expression of c-MYC and TSP-1 in cancer cells
Journal Articles

Abstract #5584: The effect of gefitinib on the expression of TSP-1 in cancer cells

Mitsuhiro Suenaga, Shin-ichi Akiyama, Chuwa Tei
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 5584.
Published: 01 May 2009
View article titled, Abstract #5584: The effect of gefitinib on the expression of TSP-1 in cancer cells
Journal Articles

Abstract #4023: Molecular basis for the induction of interleukin-8 by thymidine phosphorylase

Sho Tabata, Masatatsu Yamamoto, Ryuji Ikeda, Tatsuhiko Furukawa, Yasuo Takeda, Katsushi Yamada, Shin-ichi Akiyama
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4023.
Published: 01 May 2009
View article titled, Abstract #4023: Molecular basis for the induction of interleukin-8 by thymidine phosphorylase
Journal Articles

Molecular Basis for the Induction of an Angiogenesis Inhibitor, Thrombospondin-1, by 5-Fluorouracil

Hong-Ye Zhao, Akio Ooyama, Masatatsu Yamamoto, Ryuji Ikeda, Misako Haraguchi, Sho Tabata, Tatsuhiko Furukawa, Xiao-Fang Che, Shaoxuan Zhang, Toshinori Oka, Masakazu Fukushima, Masayuki Nakagawa, Mayumi Ono, Michihiko Kuwano, Shin-ichi Akiyama
Journal: Cancer Research
Cancer Res (2008) 68 (17): 7035–7041.
https://doi.org/10.1158/0008-5472.CAN-07-6496
Published: 28 August 2008
View article titled, Molecular Basis for the Induction of an Angiogenesis Inhibitor, Thrombospondin-1, by 5-Fluorouracil
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Includes: Supplementary data
Journal Articles

Anti-angiogenic effect of 5-Fluorouracil-based drugs against human colon cancer xenografts

Akio ooyama, Toshinori Oka, Hong-ye Zhao, Masatatsu Yamamoto, Shin-ichi Akiyama, Masakazu Fukushima
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3340.
Published: 01 May 2008
View article titled, Anti-angiogenic effect of 5-Fluorouracil-based drugs against human colon cancer xenografts
Journal Articles

Copper-Transporting P-Type ATPase, ATP7A, Confers Multidrug Resistance and Its Expression Is Related to Resistance to SN-38 in Clinical Colon Cancer

Satsuki Owatari, Satoshi Akune, Masaharu Komatsu, Ryuji Ikeda, Stephen D. Firth, Xiao-Fang Che, Masatatsu Yamamoto, Kazutake Tsujikawa, Masaki Kitazono, Takashi Ishizawa, Toru Takeuchi, Takashi Aikou, Julian F.B. Mercer, Shin-ichi Akiyama, Tatsuhiko Furukawa
Journal: Cancer Research
Cancer Res (2007) 67 (10): 4860–4868.
https://doi.org/10.1158/0008-5472.CAN-06-3096
Published: 17 May 2007
View article titled, Copper-Transporting P-Type ATPase, ATP7A, Confers Multidrug Resistance and Its Expression Is Related to Resistance to SN-38 in Clinical Colon Cancer
Open the PDF for Copper-Transporting P-Type ATPase, ATP7A, Confers Multidrug Resistance and Its Expression Is Related to Resistance to SN-38 in Clinical Colon Cancer in another window
Includes: Supplementary data
Journal Articles

Thymidine phosphorylase suppresses apoptosis induced by microtubule-interfering agents

Jeung Hei-Cheul, Young Lee, Hyun Cheol Chung, Sun Young Rha, Shin-Ichi Akiyama, Jae Kyung Roh
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 953–954.
Published: 15 April 2006
View article titled, Thymidine phosphorylase suppresses apoptosis induced by microtubule-interfering agents
Journal Articles

The role of ABCB6 in multidrug resistance

Jill K. Paterson, Gergely Szakacs, Tokushi Tachiwada, Shin-Ichi Akiyama, Michael M. Gottesman
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 122.
Published: 01 May 2005
View article titled, The role of ABCB6 in multidrug resistance
Journal Articles

GSH inhibits trypsinization of the C-terminal half of human MRP1

Xiao-Qin Ren, Tatsuhiko Furukawa, Shin-Ichi Akiyama
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 122.
Published: 01 May 2005
View article titled, GSH inhibits trypsinization of the C-terminal half of human MRP1
Journal Articles

Prevention of DNA damage-induced apoptosis by the angiogenic factor thymidine phosphorylase

Hei-Cheul Jeung, Young Lee, Sun Young Rha, Hyun Cheol Chung, Jae Kyung Roh, Shin-Ichi Akiyama, Ho Yeong Lim
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 193.
Published: 01 May 2005
View article titled, Prevention of DNA damage-induced apoptosis by the angiogenic factor thymidine phosphorylase
Journal Articles

Inhibition of Metastasis of Tumor Cells Overexpressing Thymidine Phosphorylase by 2-Deoxy-l-Ribose

Yuichi Nakajima, Takenari Gotanda, Hiroshi Uchimiya, Tatsuhiko Furukawa, Misako Haraguchi, Ryuji Ikeda, Tomoyuki Sumizawa, Hiroki Yoshida, Shin-ichi Akiyama
Journal: Cancer Research
Cancer Res (2004) 64 (5): 1794–1801.
https://doi.org/10.1158/0008-5472.CAN-03-2597
Published: 02 March 2004
View article titled, Inhibition of Metastasis of Tumor Cells Overexpressing Thymidine Phosphorylase by 2-Deoxy-<sc>l</sc>-Ribose
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Journal Articles

Suppression of Thymidine Phosphorylase-mediated Angiogenesis and Tumor Growth by 2-Deoxy-l-ribose1

Hiroshi Uchimiya, Tatsuhiko Furukawa, Masahiro Okamoto, Yuichi Nakajima, Shigeto Matsushita, Ryuji Ikeda, Takenari Gotanda, Misako Haraguchi, Tomoyuki Sumizawa, Mayumi Ono, Michihiko Kuwano, Tamotsu Kanzaki, Shin-ichi Akiyama
Journal: Cancer Research
Cancer Res (2002) 62 (10): 2834–2839.
Published: 01 May 2002
View article titled, Suppression of Thymidine Phosphorylase-mediated Angiogenesis and Tumor Growth by 2-Deoxy-<sc>l</sc>-ribose1
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Journal Articles

Interferon γ-dependent Induction of Thymidine Phosphorylase/Platelet-derived Endothelial Growth Factor through γ-Activated Sequence-like Element in Human Macrophages

Hisatsugu Goto, Kimitoshi Kohno, Saburo Sone, Shin-ichi Akiyama, Michihiko Kuwano, Mayumi Ono
Journal: Cancer Research
Cancer Res (2001) 61 (2): 469–473.
Published: 01 January 2001
View article titled, Interferon γ-dependent Induction of Thymidine Phosphorylase/Platelet-derived Endothelial Growth Factor through γ-Activated Sequence-like Element in Human Macrophages
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Journal Articles

Suppression of Metastasis by Thymidine Phosphorylase Inhibitor

Sonshin Takao, Shin-ichi Akiyama, Akihiro Nakajo, Hiroyoshi Yoh, Masaki Kitazono, Shoji Natsugoe, Kazutaka Miyadera, Masakazu Fukushima, Yuji Yamada, Takashi Aikou
Journal: Cancer Research
Cancer Res (2000) 60 (19): 5345–5348.
Published: 01 October 2000
View article titled, Suppression of Metastasis by Thymidine Phosphorylase Inhibitor
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Journal Articles

Copper-transporting P-Type Adenosine Triphosphatase (ATP7B) Is Associated with Cisplatin Resistance

Masaharu Komatsu, Tomoyuki Sumizawa, Masato Mutoh, Zhe-Sheng Chen, Kunihiko Terada, Tatsuhiko Furukawa, Xiao-Li Yang, Hui Gao, Naoyuki Miura, Toshihiro Sugiyama, Shin-ichi Akiyama
Journal: Cancer Research
Cancer Res (2000) 60 (5): 1312–1316.
Published: 01 March 2000
View article titled, Copper-transporting P-Type Adenosine Triphosphatase (ATP7B) Is Associated with Cisplatin Resistance
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Journal Articles

The Effect of a Thymidine Phosphorylase Inhibitor on Angiogenesis and Apoptosis in Tumors

Shigeto Matsushita, Takao Nitanda, Tatsuhiko Furukawa, Tomoyuki Sumizawa, Ayako Tani, Kengo Nishimoto, Suminori Akiba, Kazutaka Miyadera, Masakazu Fukushima, Yuji Yamada, Hiroki Yoshida, Tamotsu Kanzaki, Shin-ichi Akiyama
Journal: Cancer Research
Cancer Res (1999) 59 (8): 1911–1916.
Published: 15 April 1999
View article titled, The Effect of a Thymidine Phosphorylase Inhibitor on Angiogenesis and Apoptosis in Tumors
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Journal Articles

A Canalicular Multispecific Organic Anion Transporter (cMOAT) Antisense cDNA Enhances Drug Sensitivity in Human Hepatic Cancer Cells

Koji Koike, Takeshi Kawabe, Toshiya Tanaka, Satoshi Toh, Takeshi Uchiumi, Morimasa Wada, Shin-ichi Akiyama, Mayumi Ono, Michihiko Kuwano
Journal: Cancer Research
Cancer Res (1997) 57 (24): 5475–5479.
Published: 01 December 1997
View article titled, A Canalicular Multispecific Organic Anion Transporter (<em>cMOAT</em>) Antisense cDNA Enhances Drug Sensitivity in Human Hepatic Cancer Cells
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Journal Articles

A Human Canalicular Multispecific Organic Anion Transporter (cMOAT) Gene Is Overexpressed in Cisplatin-resistant Human Cancer Cell Lines with Decreased Drug Accumulation

Ken Taniguchi, Morimasa Wada, Kimitoshi Kohno, Takanori Nakamura, Takeshi Kawabe, Mina Kawakami, Kazuhiro Kagotani, Katsuzumi Okumura, Shin-ichi Akiyama, Michihiko Kuwano
Journal: Cancer Research
Cancer Res (1996) 56 (18): 4124–4129.
Published: 01 September 1996
View article titled, A Human Canalicular Multispecific Organic Anion Transporter (cMOAT) Gene Is Overexpressed in Cisplatin-resistant Human Cancer Cell Lines with Decreased Drug Accumulation
Open the PDF for A Human Canalicular Multispecific Organic Anion Transporter (cMOAT) Gene Is Overexpressed in Cisplatin-resistant Human Cancer Cell Lines with Decreased Drug Accumulation in another window