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Journal Articles

Abstract 1035: Identification of fibroblast growth factor receptors (FGFRs) alterations (alts) at DNA and RNA-level by one-step next-generation sequencing (NGS) panel

Min Qing, Xuejun Chen, Wenqing Su, Xiaofang Zhuo, Ting Shen, Chengjuan Xiong, Xuesong Lyu, Renee Tate, Qibiao Wu, Longen Zhou, Shibu Thomas, Wangwang Ning, Jianqing Wang, Huihui Yan, Zhiqiang Yin, Zhan Huang, Yaxin Xue, Changbin Zhu
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1035.
https://doi.org/10.1158/1538-7445.AM2024-1035
Published: 22 March 2024
View article titled, Abstract 1035: Identification of fibroblast growth factor receptors (FGFRs) alterations (alts) at DNA and RNA-level by one-step next-generation sequencing (NGS) panel
Journal Articles

Abstract 5099: Prevalence of fibroblast growth factor receptor (FGFR) alterations (alts) and programmed death-ligand 1 (PD-L1) expression (exp) in Chinese solid tumor patients (pts)

Min Qing, Fei Yang, Xiaowei Chen, Xuesong Lyu, Aodi Wang, Yanfei Yu, Shibu Thomas, Longen Zhou
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5099.
https://doi.org/10.1158/1538-7445.AM2024-5099
Published: 22 March 2024
View article titled, Abstract 5099: Prevalence of fibroblast growth factor receptor (<em>FGFR</em>) alterations (alts) and programmed death-ligand 1 (PD-L1) expression (exp) in Chinese solid tumor patients (pts)
Journal Articles

Abstract 7570: Molecular subtyping and immunohistochemistry validation identifies muscle Invasive bladder cancer subgroups with poorer overall survival

Jiarui Zhang, Mingxiao Feng, Neil Beeharry, Shibu Thomas, Ralph Wirtz, Arndt Hartmann, Markus Eckstein, Woonyoung Choi
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7570.
https://doi.org/10.1158/1538-7445.AM2024-7570
Published: 22 March 2024
View article titled, Abstract 7570: Molecular subtyping and immunohistochemistry validation identifies muscle Invasive bladder cancer subgroups with poorer overall survival
Journal Articles

Abstract 4133: High prevalence and heterogeneity of emergence of BRCA reversion mutations at progression on niraparib treatment in BRCA-mutant metastatic castration-resistant prostate cancer (mCRPC) patients

Karen Urtishak, Gerhardt Attard, Tokuwa Kanno, Shibu Thomas, Gary E. Mason, Byron Espina, Eugene Zhu, Natalie Hutnick, Mary Guckert, Adam del Corral, Mark Li, Angela Lopez-Gitlitz, Kim Chi, William Kevin Kelly, Evan Y. Yu, Karim Fizazi, Matthew Smith
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4133.
https://doi.org/10.1158/1538-7445.AM2022-4133
Published: 15 June 2022
View article titled, Abstract 4133: High prevalence and heterogeneity of emergence of <em>BRCA</em> reversion mutations at progression on niraparib treatment in <em>BRCA</em>-mutant metastatic castration-resistant prostate cancer (mCRPC) patients
Journal Articles

Abstract 3197: Transcriptional characterization of immunological features observed in localized and metastatic prostate cancer

Justin Lucas, Clemente Aguilar, Michael Gormley, Shibu Thomas, Natalie Hutnick, John Loffredo
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 3197.
https://doi.org/10.1158/1538-7445.AM2021-3197
Published: 01 July 2021
View article titled, Abstract 3197: Transcriptional characterization of immunological features observed in localized and metastatic prostate cancer
Journal Articles

Abstract 359: Molecular signatures associated with long-term response to apalutamide (APA) in patients (pts) with metastatic castration-sensitive prostate cancer (mCSPC) in TITAN

Justin Lucas, Neeraj Agarwal, Felix Feng, Clemente Aguilar-Bonavides, Shibu Thomas, Michael Gormley, Suneel Mundle, Sabine Brookman-May, Sharon A. McCarthy, Anders Bjartell, Hirotsugu Uemura, Simon Chowdhury, Kim N. Chi
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 359.
https://doi.org/10.1158/1538-7445.AM2021-359
Published: 01 July 2021
View article titled, Abstract 359: Molecular signatures associated with long-term response to apalutamide (APA) in patients (pts) with metastatic castration-sensitive prostate cancer (mCSPC) in TITAN
Journal Articles

Abstract 776: Androgen receptor (AR) and non-AR aberrations associated with outcomes in metastatic castration-sensitive prostate cancer (mCSPC) treated with apalutamide (APA) plus androgen deprivation therapy (ADT) in TITAN

Kim N. Chi, Shibu Thomas, Michael Gormley, Dong Shen, Neeraj Agarwal, Felix Feng, Gerhardt Attard, Alex Wyatt, Deborah S. Ricci, Angela Lopez-Gitlitz, Julie S. Larsen, Branko Miladinovic, Simon Chowdhury
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 776.
https://doi.org/10.1158/1538-7445.AM2020-776
Published: 15 August 2020
View article titled, Abstract 776: Androgen receptor (AR) and non-AR aberrations associated with outcomes in metastatic castration-sensitive prostate cancer (mCSPC) treated with apalutamide (APA) plus androgen deprivation therapy (ADT) in TITAN
Journal Articles

Abstract 5425: Novel molecular subtypes identified in prostate cancer: Results from the SPARTAN study

Clemente Aguilar, Michael Gormley, Shibu Thomas, Paul N. Mainwaring, David Olmos, Fred Saad, Simon Chowdhury, Elai Davicioni, Yang Liu, Deborah S. Ricci, Angela Lopez-Gitlitz, Margaret K. Yu, Matthew R. Smith, Eric J. Small, Felix Feng
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5425.
https://doi.org/10.1158/1538-7445.AM2020-5425
Published: 15 August 2020
View article titled, Abstract 5425: Novel molecular subtypes identified in prostate cancer: Results from the SPARTAN study
Journal Articles

Abstract 1335: Digital droplet PCR (ddPCR)-based detection of androgen receptor splice variant 7 (AR-v7) in non-metastatic castration resistant prostate cancer

Mel Pilar Espaillat, Yashoda Rajpurohit, Mike Gormley, Denis Smirnov, Ian McCaffery, Angela Lopez-Gitlitz, Deborah Ricci, Shibu Thomas
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1335.
https://doi.org/10.1158/1538-7445.AM2019-1335
Published: 01 July 2019
View article titled, Abstract 1335: Digital droplet PCR (ddPCR)-based detection of androgen receptor splice variant 7 (AR-v7) in non-metastatic castration resistant prostate cancer
Journal Articles

Abstract CT129: Identifying molecular determinants of response to apalutamide (APA) in patients (pts) with nonmetastatic castration-resistant prostate cancer (nmCRPC) in the SPARTAN study

Felix Feng, Shibu Thomas, Michael Gormley, Angela Lopez-Gitlitz, Margaret K. Yu, Shinta Cheng, Deborah S. Ricci, Brendan Rooney, Paul N. Mainwaring, David Olmos, Fred Saad, Simon Chowdhury, Boris Hadaschik, Nick Fishbane, Elai Davicioni, Yang Liu, Eric J. Small, Matthew R. Smith
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT129.
https://doi.org/10.1158/1538-7445.AM2019-CT129
Published: 01 July 2019
View article titled, Abstract CT129: Identifying molecular determinants of response to apalutamide (APA) in patients (pts) with nonmetastatic castration-resistant prostate cancer (nmCRPC) in the SPARTAN study
Journal Articles

Abstract 2605: Androgen receptor (AR) anomalies and efficacy of apalutamide (APA) in patients (pts) with nonmetastatic castration-resistant prostate cancer (nmCRPC) from the phase 3 SPARTAN study

Matthew R. Smith, Shibu Thomas, Simon Chowdhury, David Olmos, Jinhui Li, Paul N. Mainwaring, Stéphane Oudard, Felix Y. Feng, Michael Gormley, Deborah S. Ricci, Brendan Rooney, Angela Lopez-Gitlitz, Margaret K. Yu, Eric J. Small
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2605.
https://doi.org/10.1158/1538-7445.AM2018-2605
Published: 01 July 2018
View article titled, Abstract 2605: Androgen receptor (AR) anomalies and efficacy of apalutamide (APA) in patients (pts) with nonmetastatic castration-resistant prostate cancer (nmCRPC) from the phase 3 SPARTAN study
Journal Articles

Abstract 5538: Arv7 validation in castrate resistant prostate tumors utilizing Rnascope in situ hybridization assay

Tanesha Cash-Mason, Jackson Wong, Martinez Martinez, Michael Sharp, Jayaprakash Karkera, John D. Alvarez, Gerald C. Chu, Shibu Thomas, Weiman Li, S. Ken Tian
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5538.
https://doi.org/10.1158/1538-7445.AM2018-5538
Published: 01 July 2018
View article titled, Abstract 5538: Arv7 validation in castrate resistant prostate tumors utilizing Rnascope <em>in situ</em> hybridization assay
Journal Articles

Abstract 2755: Comparison of blood based liquid biopsy methodologies for improved risk assessment of prostate cancer (PCa)

Yashoda Rajpurohit, Shibu Thomas, Jaymala Patel, Dong Shen, Michael Gormley, Denis Smirnov, Deborah Ricci
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2755.
https://doi.org/10.1158/1538-7445.AM2017-2755
Published: 01 July 2017
View article titled, Abstract 2755: Comparison of blood based liquid biopsy methodologies for improved risk assessment of prostate cancer (PCa)
Journal Articles

Abstract 670: Integrative genomic analysis of alterations driving anti-androgen treatment resistance in vitro

Dong Shen, Brendan Hodkinson, Deborah Ricci, Karin Verstraeten, Michael Schaffer, Michael Gormley, Shibu Thomas
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 670.
https://doi.org/10.1158/1538-7445.AM2017-670
Published: 01 July 2017
View article titled, Abstract 670: Integrative genomic analysis of alterations driving anti-androgen treatment resistance in vitro
Journal Articles

Abstract 3074: Addition of ARN509 and docetaxel, alone or in combination, to castration demonstrates improved efficacy and heterogeneity of molecular response in prostate cancer patient-derived xenografts

Ryan McMullin, Himanshu Gupta, Yashoda Rajpurohit, Holly Nguyen, Lisha Brown, Daniel Sondheim, Gormley Michael, Deborah Ricci, Shibu Thomas, Corey Eva
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3074.
https://doi.org/10.1158/1538-7445.AM2016-3074
Published: 15 July 2016
View article titled, Abstract 3074: Addition of ARN509 and docetaxel, alone or in combination, to castration demonstrates improved efficacy and heterogeneity of molecular response in prostate cancer patient-derived xenografts
Journal Articles

Abstract 4313: Abiraterone acetate (AA) treatment of prostate cancer patient-derived xenografts (PDX) demonstrates heterogeneity of responses and identifies potential biomarkers of adaptive resistance

Hung-Ming Lam, Ryan McMullin, Holly M. Nguyen, Michael Gormley, Roman Gulati, Weimin Li, Deborah Ricci, Karin Verstraeten, Shibu Thomas, Elahe A. Mostaghel, Peter S. Nelson, Robert L. Vessella, Eva Corey
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4313.
https://doi.org/10.1158/1538-7445.AM2015-4313
Published: 01 August 2015
View article titled, Abstract 4313: Abiraterone acetate (AA) treatment of prostate cancer patient-derived xenografts (PDX) demonstrates heterogeneity of responses and identifies potential biomarkers of adaptive resistance
Journal Articles

Abstract CT134: Androgen receptor (AR) mutations in patients (pts) with castration-resistant prostate cancer (CRPC) with and without prior abiraterone acetate (AA) treatment

Dana E. Rathkopf, Matthew R. Smith, Emmanuel S. Antonarakis, Charles J. Ryan, William R. Berry, Neal D. Shore, Glenn Liu, Celestia Higano, Joshi J. Alumkal, Ralph Hauke, Ronald Tutrone, Mansoor Saleh, Edna Chow Maneval, Shibu Thomas, Deborah Ricci, Margaret K. Yu, Carla J. de Boer, Angela Trinh, Thian Kheoh, Rajesh Bandekar, Howard I. Scher
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): CT134.
https://doi.org/10.1158/1538-7445.AM2015-CT134
Published: 01 August 2015
View article titled, Abstract CT134: Androgen receptor (AR) mutations in patients (pts) with castration-resistant prostate cancer (CRPC) with and without prior abiraterone acetate (AA) treatment
Journal Articles

Abstract 3308: A-kinase anchoring protein 2 is required for calcitonin receptor-stimulated invasion of prostate cancer cells

Ahmed Aljameeli, Arvind Thakkar, Shibu Thomas, Girish V. Shah
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3308.
https://doi.org/10.1158/1538-7445.AM2014-3308
Published: 01 October 2014
View article titled, Abstract 3308: A-kinase anchoring protein 2 is required for calcitonin receptor-stimulated invasion of prostate cancer cells
Journal Articles

CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis

Shibu Thomas, Michael A. Harding, Steven C. Smith, Jonathan B. Overdevest, Matthew D. Nitz, Henry F. Frierson, Scott A. Tomlins, Glen Kristiansen, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2012) 72 (21): 5600–5612.
https://doi.org/10.1158/0008-5472.CAN-11-3666
Published: 31 October 2012
View article titled, CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis
Open the PDF for CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 4218: Calcitonin receptor increases invasion of prostate cancer cells by activating cAMP-dependent protein kinase (PKA) and promoting phosphorylation of tight junction proteins

Girish V. Shah, Shibu Thomas, Arvind Thakkar, Alan Fanning
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4218.
https://doi.org/10.1158/1538-7445.AM2012-4218
Published: 15 April 2012
View article titled, Abstract 4218: Calcitonin receptor increases invasion of prostate cancer cells by activating cAMP-dependent protein kinase (PKA) and promoting phosphorylation of tight junction proteins