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Journal Articles

The Immune Contexture Associates with the Genomic Landscape in Lung Adenomatous Premalignancy

Kostyantyn Krysan, Linh M. Tran, Brandon S. Grimes, Gregory A. Fishbein, Atsuko Seki, Brian K. Gardner, Tonya C. Walser, Ramin Salehi-Rad, Jane Yanagawa, Jay M. Lee, Sherven Sharma, Denise R. Aberle, Arum E. Spira, David A. Elashoff, William D. Wallace, Michael C. Fishbein, Steven M. Dubinett
Journal: Cancer Research
Cancer Res (2019) 79 (19): 5022–5033.
https://doi.org/10.1158/0008-5472.CAN-19-0153
Published: 01 October 2019
View articletitled, The Immune Contexture Associates with the Genomic Landscape in Lung Adenomatous Premalignancy
Open the PDF for The Immune Contexture Associates with the Genomic Landscape in Lung Adenomatous Premalignancy in another window
Includes: Supplementary data
Journal Articles

Abstract 3214: In situ vaccination with CCL21-modified dendritic cells (CCL21-DC) combined with checkpoint blockade in murine models of NSCLC

Raymond J. Lim, Ramin Salehirad, Bin Liu, Rui Li, Linh M. Tran, Kostyantyn Krysan, Stephanie Ong, Zi L. Huang, David B. Shackelford, Sherven Sharma, Steven M. Dubinett
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3214.
https://doi.org/10.1158/1538-7445.AM2019-3214
Published: 01 July 2019
View articletitled, Abstract 3214: In situ vaccination with CCL21-modified dendritic cells (CCL21-DC) combined with checkpoint blockade in murine models of NSCLC
Journal Articles

Abstract CT226: A Phase I trial of in situ vaccination with autologous CCL21-modified dendritic cells (CCL21-DC) combined with pembrolizumab for advanced NSCLC

Bin Liu, Edward B. Garon, Aaron E. Lisberg, Ramin Salehi-Rad, Jay M. Lee, Linh M. Tran, Kostyantyn Krysan, Rui Li, Raymond J. Lim, Manash Paul, Ying Lin, Zhe Jing, Fereidoun Abtin, Robert D. Suh, Scott Oh, Denise R. Aberle, Lauren E. Winter, William Dean Wallace, David Elashoff, Sherven Sharma, Steven M. Dubinett
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT226.
https://doi.org/10.1158/1538-7445.AM2019-CT226
Published: 01 July 2019
View articletitled, Abstract CT226: A Phase I trial of in situ vaccination with autologous CCL21-modified dendritic cells (CCL21-DC) combined with pembrolizumab for advanced NSCLC
Journal Articles

Silencing the Snail-Dependent RNA Splice Regulator ESRP1 Drives Malignant Transformation of Human Pulmonary Epithelial Cells

Tonya C. Walser, Zhe Jing, Linh M. Tran, Ying Q. Lin, Natalie Yakobian, Gerald Wang, Kostyantyn Krysan, Li X. Zhu, Sherven Sharma, Mi-Heon Lee, John A. Belperio, Aik T. Ooi, Brigitte N. Gomperts, Jerry W. Shay, Jill E. Larsen, John D. Minna, Long-sheng Hong, Michael C. Fishbein, Steven M. Dubinett
Journal: Cancer Research
Cancer Res (2018) 78 (8): 1986–1999.
https://doi.org/10.1158/0008-5472.CAN-17-0315
Published: 12 April 2018
View articletitled, Silencing the Snail-Dependent RNA Splice Regulator ESRP1 Drives Malignant Transformation of Human Pulmonary Epithelial Cells
Open the PDF for Silencing the Snail-Dependent RNA Splice Regulator ESRP1 Drives Malignant Transformation of Human Pulmonary Epithelial Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 2324: FRA1 contributes to ERK-mediated increased PD-L1 expression in KRAS mutated premalignant human bronchial epithelial cells

Mi-Heon Lee, Jane Yanagawa, Tonya C Walser, Jonathan W. Goldman, Edward B. Garon, Gang Zeng, Sherven Sharma, Boning Gao, John Minna, Steven M. Dubinett, Jay M Lee
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2324.
https://doi.org/10.1158/1538-7445.AM2016-2324
Published: 15 July 2016
View articletitled, Abstract 2324: FRA1 contributes to ERK-mediated increased PD-L1 expression in KRAS mutated premalignant human bronchial epithelial cells
Journal Articles

Abstract 5170: Snail-dependent ESRP1 silencing drives malignant conversion of human pulmonary epithelial cells

Tonya C. Walser, Zhe Jing, Linh Tran, Ying Lin, Li Zhu, Sherven Sharma, Aik Ooi, Brigitte N. Gomperts, Jerry W. Shay, Jill E. Larsen, Boning Gao, John D. Minna, Micihael C. Fishbein, Steven M. Dubinett
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5170.
https://doi.org/10.1158/1538-7445.AM2016-5170
Published: 15 July 2016
View articletitled, Abstract 5170: Snail-dependent ESRP1 silencing drives malignant conversion of human pulmonary epithelial cells
Journal Articles

Abstract 1723: Novel drug candidates CEP1430 and CEP1507 against cancer stem cells and circulating tumor cells in advanced stage pancreatic cancer

Cristian Sharma, Padmini Narayanan, Michael Sharma, Robert Rodriguez, Miriam Navel, Donna Stanton, Natalee Amezcua, Shaleekha Sharma, Mandana Amiri, Jitesh Jani, Sherven Sharma, Jay P. Sharma
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1723.
https://doi.org/10.1158/1538-7445.AM2016-1723
Published: 15 July 2016
View articletitled, Abstract 1723: Novel drug candidates CEP1430 and CEP1507 against cancer stem cells and circulating tumor cells in advanced stage pancreatic cancer
Journal Articles

Abstract 4361: Efficacy of MET inhibitors in NSCLC with CBL alterations

Yi-Hung Carol Tan, Cleo Rolle, Li Zhu, Minu K. Srivastava, Sherven Sharma, Ravi Salgia
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4361.
https://doi.org/10.1158/1538-7445.AM2015-4361
Published: 01 August 2015
View articletitled, Abstract 4361: Efficacy of MET inhibitors in NSCLC with CBL alterations
Journal Articles

Abstract A17: Tumor Snail knockdown reduces tumor burden and metastases by inducing antitumor immune responses in lung cancer

Minu K. Srivastava, Sherven Sharma, Li Zhu, Min Huang, Åsa Andersson, Marni Harris-White, Upendra K. Kar, Longsheng Hong, Michael Fishbein, Steven Dubinett
Journal: Cancer Research
Cancer Res (2011) 71 (18_Supplement): A17.
https://doi.org/10.1158/1538-7445.FBCR11-A17
Published: 28 October 2014
View articletitled, Abstract A17: Tumor Snail knockdown reduces tumor burden and metastases by inducing antitumor immune responses in lung cancer
Journal Articles

Abstract 1141: p53-dependent regulation of epithelial-to-mescenchymal transition by nf-κb in head and neck squamous cell carcinoma

Yuan Lin, Jie Luo, Elliot Abemayor, Sherven Sharma, Steven Dubinett, Maie S. John
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1141.
https://doi.org/10.1158/1538-7445.AM2014-1141
Published: 01 October 2014
View articletitled, Abstract 1141: p53-dependent regulation of epithelial-to-mescenchymal transition by nf-κb in head and neck squamous cell carcinoma
Journal Articles

Abstract 4581: A novel modular polymer platform for the treatment of oral and head and neck carcinoma

Yuan Lin, Sherven Sharma, Steven M. Dubinett, Ben Wu, Maie St. John
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4581.
https://doi.org/10.1158/1538-7445.AM2014-4581
Published: 01 October 2014
View articletitled, Abstract 4581: A novel modular polymer platform for the treatment of oral and head and neck carcinoma
Journal Articles

Abstract 339: Apricoxib, a selective COX-2 inhibitor, suppresses IL-27-mediated STAT3 activation and potentiates its inhibition of epithelial to mesenchymal transition in human non-small cell lung cancer

Puja Kachroo, Mi-Heon Lee, Gina Lee, Kostyantyn Krysan, Tonya C. Walser, Sherven Sharma, Sara Zaknoen, Steven M. Dubinett, Jay M. Lee
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 339.
https://doi.org/10.1158/1538-7445.AM2012-339
Published: 15 April 2012
View articletitled, Abstract 339: Apricoxib, a selective COX-2 inhibitor, suppresses IL-27-mediated STAT3 activation and potentiates its inhibition of epithelial to mesenchymal transition in human non-small cell lung cancer
Journal Articles

Abstract 3425: Interleukin-27 inhibits epithelial mesenchymal transition in lung carcinogenesis

Jay M. Lee, Ling Zhang, Puja Kachroo, Xiaoyan Cui, Saswati Hazra, Tonya C. Walser, John D. Minna, Sherven Sharma, Steven M. Dubinett
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3425.
https://doi.org/10.1158/1538-7445.AM2011-3425
Published: 15 April 2011
View articletitled, Abstract 3425: Interleukin-27 inhibits epithelial mesenchymal transition in lung carcinogenesis
Journal Articles

Abstract 4371: Optimal drug concentration screening and evaluation in cancer stem cells & 3D tumor stem cell cultures drug response assays in association with clinical efficacy for melanoma cancer stem cell

Jenna Passarini, John Patrick Cleary, Preetham Kumar, Trisha Newton, Sharmila Shankar, Cristian Sharma, Michael Sharma, Rubio R. Punzalan, Bhuvesh K. Sharma, Sherven Sharma, Parkash Gill, Rakesh K. Srivastava, Jay P. Sharma
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4371.
https://doi.org/10.1158/1538-7445.AM2011-4371
Published: 15 April 2011
View articletitled, Abstract 4371: Optimal drug concentration screening and evaluation in cancer stem cells & 3D tumor stem cell cultures drug response assays in association with clinical efficacy for melanoma cancer stem cell
Journal Articles

Abstract 3306: Screening potential drug candidates for treatment of glioblastoma patients utilizing an in-vivo mouse/ rat model system

Jenna Passarini, John P. Cleary, Preetham Kumar, Trisha Newton, Michael Sharma, Cristian Sharma, Rubio R. Panunzalan, Parkash Gill, Sherven Sharma, Rakesh Srivastava, Sharmila Shankar, Jay P. Sharma
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3306.
https://doi.org/10.1158/1538-7445.AM2011-3306
Published: 15 April 2011
View articletitled, Abstract 3306: Screening potential drug candidates for treatment of glioblastoma patients utilizing an in-vivo mouse/ rat model system
Journal Articles

Abstract 1474: Polo-like kinase-1 regulation by cyclooxygenase-2 in non small cell lung cancer

Kyu Hwa Lee, Sang-Min Lee, Jae-Jun Yim, Chul-Gyu Yoo, Choon-Taek Lee, Young Whan Kim, Sung Koo Han, Young-Soo Shim, Sherven Sharma, Steven M. Dubinett, Seok-Chul Yang
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1474.
https://doi.org/10.1158/1538-7445.AM10-1474
Published: 15 April 2010
View articletitled, Abstract 1474: Polo-like kinase-1 regulation by cyclooxygenase-2 in non small cell lung cancer
Journal Articles

Abstract #175: Evaluation of intratumoral heterogeneity of malignant pleural effusion and detection of lung cancer initiating cells

Saroj Basak, Mysore Veena, Scott Oh, Ge Huang, Eri Srivatsan, Min Huang, Sherven Sharma, Raj Batra
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 175.
Published: 01 May 2009
View articletitled, Abstract #175: Evaluation of intratumoral heterogeneity of malignant pleural effusion and detection of lung cancer initiating cells
Journal Articles

Abstract #4963: Proinflammatory mediators up-regulate snail in head and neck squamous sell carcinoma

Maie St. John, Mariam Dohadwala, Jie Luo, Guanyu Wang, Li Zhu, Sherven Sharma, Steven Dubinett
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4963.
Published: 01 May 2009
View articletitled, Abstract #4963: Proinflammatory mediators up-regulate snail in head and neck squamous sell carcinoma
Journal Articles

Abstract #1144: IL-7/IL-7R alpha-Fc immune modulation in lung cancer

Åsa Andersson, Li Zhu, David Elashoff, Robert Strieter, Steven Dubinett, Sherven Sharma
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1144.
Published: 01 May 2009
View articletitled, Abstract #1144: IL-7/IL-7R alpha-Fc immune modulation in lung cancer
Journal Articles

Abstract #3872: NGAL mediates erlotinib resistance in NSCLC

Xiaoyan Cui, Li Zhu, Kostyantyn Krysan, Jie Luo, Sherven Sharma, Steven Dubinett
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3872.
Published: 01 May 2009
View articletitled, Abstract #3872: NGAL mediates erlotinib resistance in NSCLC