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Journal Articles

Comparative Single-Cell Transcriptomics of Human Neuroblastoma and Preclinical Models Reveals Conservation of an Adrenergic Cell State

Bethel Tesfai Embaie, Hirak Sarkar, Adele M. Alchahin, Jörg Otte, Thale Kristin Olsen, Conny Tümmler, Polina Kameneva, Artem V. Artemov, Natalia Akkuratova, Igor Adameyko, Jan-Bernd Stukenborg, Malin Wickström, Per Kogner, John Inge Johnsen, Shenglin Mei, Peter V. Kharchenko, Ninib Baryawno

Cancer Res (2025) 85 (6): 1015–1034.

https://doi.org/10.1158/0008-5472.CAN-24-1507

Published: 14 March 2025

View articletitled, Comparative Single-Cell Transcriptomics of Human Neuroblastoma and Preclinical Models Reveals Conservation of an Adrenergic Cell State

Includes: Supplementary data

Journal Articles

Abstract CT069: Targeting EpCAM via CAR T-cells is an effective treatment for gastric cancer patients and subsequent toll-like receptor signaling activation in CD36+ monocyte underlies the resulting cytokine release syndrome

TIanhang Luo, Zhengmao Lu, Zhongen Wu, Yuxuan Dong, Yuanyuan Zhu, Mei Feng, Shenglin Mei, Weijia Fang, Di Zhu

Cancer Res (2024) 84 (7_Supplement): CT069.

https://doi.org/10.1158/1538-7445.AM2024-CT069

Published: 05 April 2024

View articletitled, Abstract CT069: Targeting EpCAM via CAR T-cells is an effective treatment for gastric cancer patients and subsequent toll-like receptor signaling activation in CD36+ monocyte underlies the resulting cytokine release syndrome

Journal Articles

Abstract LB342: Potent Anti-Tumor Activity Demonstrated by Anti-AXL CAR T Cell Therapy and AXL-ADC in Lung Cancer and Breast Cancer Models

Zhongen Wu, Yang Gao, Jingpeng Pei, Enfeng Zhao, Shenglin Mei, Yuxiong Feng, Di Zhu

Cancer Res (2024) 84 (7_Supplement): LB342.

https://doi.org/10.1158/1538-7445.AM2024-LB342

Published: 05 April 2024

View articletitled, Abstract LB342: Potent Anti-Tumor Activity Demonstrated by Anti-AXL CAR T Cell Therapy and AXL-ADC in Lung Cancer and Breast Cancer Models

Journal Articles

Abstract 103: Prostate cancer bone metastasis: Therapeutic targeting of tumor associated macrophages

Hanyu Zhang, Shenglin Mei, Nathan E. Jeffries, Douglas M. Dahl, Chin-Lee Wu, Philip J. Saylor, David B. Sykes

Cancer Res (2024) 84 (6_Supplement): 103.

https://doi.org/10.1158/1538-7445.AM2024-103

Published: 22 March 2024

View articletitled, Abstract 103: Prostate cancer bone metastasis: Therapeutic targeting of tumor associated macrophages

Journal Articles

Abstract 5270: Androgen receptor blockade in macrophages primes NLRP3 inflammasome-mediated phagocytosis and tumor clearance in advanced prostate cancer

Cancer Res (2024) 84 (6_Supplement): 5270.

https://doi.org/10.1158/1538-7445.AM2024-5270

Published: 22 March 2024

View articletitled, Abstract 5270: Androgen receptor blockade in macrophages primes NLRP3 inflammasome-mediated phagocytosis and tumor clearance in advanced prostate cancer

Journal Articles

Abstract 1396: Targeting immune suppressive myeloid cells in prostate cancer recurrence and metastasis

Shenglin Mei, Hanyu Zhang, Taghreed Hirz, Nathan Elias Jeffries, Shulin Wu, Chin Lee Wu, Douglas M. Dahl, Philip J. Saylor, David B. Sykes

Cancer Res (2024) 84 (6_Supplement): 1396.

https://doi.org/10.1158/1538-7445.AM2024-1396

Published: 22 March 2024

View articletitled, Abstract 1396: Targeting immune suppressive myeloid cells in prostate cancer recurrence and metastasis

Journal Articles

Abstract 631: Single-cell analysis of immune and stroma cell remodeling in renal cell carcinoma primary tumors and bone metastatic lesions

Shenglin Mei, Adele M. Alchahin, Ioanna Tsea, Youmna Kfoury, Taghreed Taghreed, Hirak Sarkar, Shulin Wu, Alexander O. Subtelny, Yida Zhang, Keyan Salari, Chin-Lee Wu, Mark A. Randolph, David T. Scadden, Douglas Dahl, John Shin, Peter Kharchenko, Philip Saylor, David Sykes, Ninib Baryawno

Cancer Res (2023) 83 (7_Supplement): 631.

https://doi.org/10.1158/1538-7445.AM2023-631

Published: 04 April 2023

View articletitled, Abstract 631: Single-cell analysis of immune and stroma cell remodeling in renal cell carcinoma primary tumors and bone metastatic lesions

Journal Articles

Abstract 1678: Single-cell landscape of the TH-MYCN neuroblastoma mouse model

Bethel Tesfai Embaie, Adele Alchahin, Thale Kristin Olsen, Hirak Sarkar, Shenglin Mei, Ninib Baryawno

Cancer Res (2022) 82 (12_Supplement): 1678.

https://doi.org/10.1158/1538-7445.AM2022-1678

Published: 15 June 2022

View articletitled, Abstract 1678: Single-cell landscape of the TH-MYCN neuroblastoma mouse model

Journal Articles

Abstract 6215: The immune cell atlas of human neuroblastoma

Bronte Manouk Verhoeven, Shenglin Mei, Thale K. Olsen, Karin K. Gustafsson, Anders Valind, Axel Lindström, David G. Nord, Shahrzad S. Fard, Catharina Hagerling, Peter V. Kharchenko, Per Kogner, John I. Johnsen, Ninib Baryawno

Cancer Res (2022) 82 (12_Supplement): 6215.

https://doi.org/10.1158/1538-7445.AM2022-6215

Published: 15 June 2022

View articletitled, Abstract 6215: The immune cell atlas of human neuroblastoma

Journal Articles

Abstract 982: A new transcriptional metastatic signature predicts survival in clear cell renal cell carcinoma

Adele Mirna Alchahin, Shenglin Mei, Ioanna Tsea, Taghreed Hirz, Youmna Kfoury, Douglas Dahl, Chin-Lee Wu, Alexander O. Subtelny, Shulin WU, David T. Scadden, John H. Shin, Philip J. Saylor, David B. Sykes, Peter V. Kharchenko, Ninib Baryawno

Cancer Res (2022) 82 (12_Supplement): 982.

https://doi.org/10.1158/1538-7445.AM2022-982

Published: 15 June 2022

View articletitled, Abstract 982: A new transcriptional metastatic signature predicts survival in clear cell renal cell carcinoma

Journal Articles

Abstract 2510: An atlas of single-cell and spatial transcriptomics reveals alterations that correlate with human prostate cancer progression

Taghreed Hirz, Shenglin Mei, Hirak Sarkar, Youmna Kfoury, Shulin Wu, Chin-Lee Wu, Fei Chen, Evan Z. Macosko, Douglas M. Dahl, Ninib Baryawno, David T. Scadden, Philip J. Saylor, Peter V. Kharchenko, David B. Sykes

Cancer Res (2022) 82 (12_Supplement): 2510.

https://doi.org/10.1158/1538-7445.AM2022-2510

Published: 15 June 2022

View articletitled, Abstract 2510: An atlas of single-cell and spatial transcriptomics reveals alterations that correlate with human prostate cancer progression

Journal Articles

Abstract IA23: Impact of metastatic prostate cancer on human bone marrow

Ninib Baryawno, Youmna Kfoury, Nicolas Severe, Shenglin Mei, Karin Gustafsson, Taghreed Hirz, Thomas Brouse, Elizabeth W. Scadden, Anna A. Igolkina, Bryan D. Choi, Nikolas Barkas, John H. Shin, Philip J. Saylor, David T. Scadden, David B. Sykes, Peter V. Kharchenko

Cancer Res (2020) 80 (21_Supplement): IA23.

https://doi.org/10.1158/1538-7445.TUMHET2020-IA23

Published: 03 November 2020

View articletitled, Abstract IA23: Impact of metastatic prostate cancer on human bone marrow

Journal Articles

Abstract 3446: High-resolution mapping of human prostate tumors- guiding better risk stratification and therapeutic approaches

Taghreed Hirz, Shenglin Mei, Youmna Kfoury, Chin-Lee Wu, Douglas M. Dahl, Philip Saylor, Peter Kharchenko, Ninib Baryawno, David Sykes

Cancer Res (2020) 80 (16_Supplement): 3446.

https://doi.org/10.1158/1538-7445.AM2020-3446

Published: 15 August 2020

View articletitled, Abstract 3446: High-resolution mapping of human prostate tumors- guiding better risk stratification and therapeutic approaches

Journal Articles

Cistrome Cancer: A Web Resource for Integrative Gene Regulation Modeling in Cancer

Shenglin Mei, Clifford A. Meyer, Rongbin Zheng, Qian Qin, Qiu Wu, Peng Jiang, Bo Li, Xiaohui Shi, Binbin Wang, Jingyu Fan, Celina Shih, Myles Brown, Chongzhi Zang, X. Shirley Liu

Cancer Res (2017) 77 (21): e19–e22.

https://doi.org/10.1158/0008-5472.CAN-17-0327

Published: 01 November 2017

View articletitled, Cistrome Cancer: A Web Resource for Integrative Gene Regulation Modeling in Cancer

Includes: Multimedia, Supplementary data

Journal Articles

Abstract 1814: IL11 mediates tumor resistance to anti-VEGF therapy in lung cancer

Jie Li, Kun Xie, Shenglin Mei, Yuanjian Xu, Hua Gu, Dong Li, Kaiming Chen, Fei Tao, Jiya Eerdeng, Jianmin Fang

Cancer Res (2017) 77 (13_Supplement): 1814.

https://doi.org/10.1158/1538-7445.AM2017-1814

Published: 01 July 2017

View articletitled, Abstract 1814: IL11 mediates tumor resistance to anti-VEGF therapy in lung cancer

Journal Articles

CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer

Taku Yoshida, Jee Hyun Kim, Kristopher Carver, Ying Su, Stanislawa Weremowicz, Laura Mulvey, Shoji Yamamoto, Cameron Brennan, Shenglin Mei, Henry Long, Jun Yao, Kornelia Polyak

Cancer Res (2015) 75 (7): 1516–1526.

https://doi.org/10.1158/0008-5472.CAN-14-2443

Published: 31 March 2015

View articletitled, CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer

Includes: Supplementary data

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Comparative Single-Cell Transcriptomics of Human Neuroblastoma and Preclinical Models Reveals Conservation of an Adrenergic Cell State

Abstract CT069: Targeting EpCAM via CAR T-cells is an effective treatment for gastric cancer patients and subsequent toll-like receptor signaling activation in CD36+ monocyte underlies the resulting cytokine release syndrome

Abstract LB342: Potent Anti-Tumor Activity Demonstrated by Anti-AXL CAR T Cell Therapy and AXL-ADC in Lung Cancer and Breast Cancer Models

Abstract 103: Prostate cancer bone metastasis: Therapeutic targeting of tumor associated macrophages

Abstract 5270: Androgen receptor blockade in macrophages primes NLRP3 inflammasome-mediated phagocytosis and tumor clearance in advanced prostate cancer

Abstract 1396: Targeting immune suppressive myeloid cells in prostate cancer recurrence and metastasis

Abstract 631: Single-cell analysis of immune and stroma cell remodeling in renal cell carcinoma primary tumors and bone metastatic lesions

Abstract 1678: Single-cell landscape of the TH-MYCN neuroblastoma mouse model

Abstract 6215: The immune cell atlas of human neuroblastoma

Abstract 982: A new transcriptional metastatic signature predicts survival in clear cell renal cell carcinoma

Abstract 2510: An atlas of single-cell and spatial transcriptomics reveals alterations that correlate with human prostate cancer progression

Abstract IA23: Impact of metastatic prostate cancer on human bone marrow

Abstract 3446: High-resolution mapping of human prostate tumors- guiding better risk stratification and therapeutic approaches

Cistrome Cancer: A Web Resource for Integrative Gene Regulation Modeling in Cancer

Abstract 1814: IL11 mediates tumor resistance to anti-VEGF therapy in lung cancer

CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer

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