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Journal Articles

Abstract PO3-28-09: Does Diffusely Infiltrating Lobular Carcinoma of the Breast Arise from Epithelial-Mesenchymal Hybrid Cells?

Andras Voros, Laszlo Tabar, Renata Bozo, Orsolya Olah, Katalin Ormandi, Zoltan Vereb, Istvan Nemeth, Peter B. Dean, Olga Puchkova, Ming-Fang Yen, Li-Sheng Chen
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO3-28-09.
https://doi.org/10.1158/1538-7445.SABCS23-PO3-28-09
Published: 02 May 2024
View articletitled, Abstract PO3-28-09: Does Diffusely Infiltrating Lobular Carcinoma of the Breast Arise from Epithelial-Mesenchymal Hybrid Cells?
Journal Articles

Abstract LB258: ZDHHC20 is a potential target for overcoming ABCB1-mediated multidrug resisance (MDR) in cancer

Ning Ji, Xin Peng, Yi-nan Liu, Yuqi Yang, Zhe-Sheng Chen, Dexin Kong, Yueguo Li
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB258.
https://doi.org/10.1158/1538-7445.AM2024-LB258
Published: 05 April 2024
View articletitled, Abstract LB258: ZDHHC20 is a potential target for overcoming ABCB1-mediated multidrug resisance (MDR) in cancer
Journal Articles

Abstract 485: Cancer killing effect of ultrasound-responsive mechanophore nanoparticles

Jian Wang, Shensheng Zhao, Junxi Yi, Yunyan Sun, Megha Agrawal, King Li, Jeffrey S. Moore, Michael Oelze, Yun-Sheng Chen
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 485.
https://doi.org/10.1158/1538-7445.AM2024-485
Published: 22 March 2024
View articletitled, Abstract 485: Cancer killing effect of ultrasound-responsive mechanophore nanoparticles
Journal Articles

Abstract 4164: Hybrid photoacoustic imaging and fast ultrasound localization microscopy to probe the tumor microenvironment

Shensheng Zhao, Sayantani Basu, Roy H. Campbell, Yang Zhao, Yun-Sheng Chen
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4164.
https://doi.org/10.1158/1538-7445.AM2024-4164
Published: 22 March 2024
View articletitled, Abstract 4164: Hybrid photoacoustic imaging and fast ultrasound localization microscopy to probe the tumor microenvironment
Journal Articles

Abstract 7193: ABCB1-mediated chemotherapeutic drug resistance is reversed by a potent p53-MDM2 inhibitor NVP-HDM201

Harsh Patel, Chaoyun Cai, Zhuoxun Wu, Qiuxu Teng, Hanli Li, Zhe-Sheng Chen
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7193.
https://doi.org/10.1158/1538-7445.AM2024-7193
Published: 22 March 2024
View articletitled, Abstract 7193: ABCB1-mediated chemotherapeutic drug resistance is reversed by a potent p53-MDM2 inhibitor NVP-HDM201
Journal Articles

Abstract 5773: Multi-omics profiling of chemotactic characteristics of brain microglia and astrocytoma

Chih-Yi Chen, Yu-Ching Huang, Wen-Hsiu Su, Yi-Ting Liu, Chi-Sheng Chen, Chia-Yang Li, Kun-Che Chang, Chia-Yen Dai, Shu-Chi Wang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5773.
https://doi.org/10.1158/1538-7445.AM2024-5773
Published: 22 March 2024
View articletitled, Abstract 5773: Multi-omics profiling of chemotactic characteristics of brain microglia and astrocytoma
Journal Articles

Abstract 6271: Discovery of BR1733 for the treatment of SWI/SNF deficient or highly vascularized solid tumor

Xinghao Wang, Shichao Ma, Min (Bella) Xie, Lele Wang, Yajun Wang, Song Zhang, Sheng Chen, Lynette Zhang, Yongqi Zhou, Mengxi Zhao, Dandan Li, Guobin Li, Xiao Fan, Hailong Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6271.
https://doi.org/10.1158/1538-7445.AM2023-6271
Published: 04 April 2023
View articletitled, Abstract 6271: Discovery of BR1733 for the treatment of SWI/SNF deficient or highly vascularized solid tumor
Journal Articles

Abstract 2843: RN486, a Bruton’s tyrosine kinase inhibitor, reverses multidrug resistance in ABCG2-overexpressing cancer cells

Xing-Duo Dong, Qisi Lu, Yi-Dong Li, Qiu-Xu Teng, Zi-Ning Lei, Zhe-Sheng Chen
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2843.
https://doi.org/10.1158/1538-7445.AM2023-2843
Published: 04 April 2023
View articletitled, Abstract 2843: RN486, a Bruton’s tyrosine kinase inhibitor, reverses multidrug resistance in ABCG2-overexpressing cancer cells
Journal Articles

Abstract 4962: Discovery of cancer-specific E3 ligase ligands for targeted protein degradation

Zhaofu Wang, Lynette Zhang, Zhen Chang, Mengxi Zhao, Guobin Li, Fang Qin, Shichao Ma, Yunfeng Li, Zhongguo Zhang, Xinghao Wang, Ying Kong, Shidi Lou, Sheng Chen, Lanzhen Liu, Shuaijie Xu, Hailong Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4962.
https://doi.org/10.1158/1538-7445.AM2023-4962
Published: 04 April 2023
View articletitled, Abstract 4962: Discovery of cancer-specific E3 ligase ligands for targeted protein degradation
Journal Articles

Abstract 360: Methyl-cantharidimide (MCA) can induce apoptosis by activating UNC5B-Netrin-1-DAPK pathway in hepatocellular carcinoma

Yi-Dong Li, Yong Mao, Xing-Duo Dong, Zi-Ning Lei, Yuqi Yang, Lizhu Lin, Dong-Hua Yang, Zhe-Sheng Chen
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 360.
https://doi.org/10.1158/1538-7445.AM2022-360
Published: 15 June 2022
View articletitled, Abstract 360: Methyl-cantharidimide (MCA) can induce apoptosis by activating UNC5B-Netrin-1-DAPK pathway in hepatocellular carcinoma
Journal Articles

Abstract 1095: Establishment and characterization of a topotecan resistant lung cancer NCI H460/TPT10 cell line and a tumor xenograft model

Qiu-Xu Teng, Zi-Ning Lei, Wei Zhang, Ying-Fang Fan, Jing-Quan Wang, Chao-Yun Cai, Dong-Hua Yang, John Wurpel, Zhe-Sheng Chen
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1095.
https://doi.org/10.1158/1538-7445.AM2022-1095
Published: 15 June 2022
View articletitled, Abstract 1095: Establishment and characterization of a topotecan resistant lung cancer NCI H460/TPT10 cell line and a tumor xenograft model
Journal Articles

Abstract 409: Reversal of ABCG2-mediated multidrug resistance by tepotinib in vitro and in vivo

Zhuoxun Wu, Qiu-Xu Teng, Yuqi Yang, Nikita Acharekar, Jing-Quan Wang, Min He, Sabesan Yoganathan, Jun Lin, Jian Wang, Zhe-Sheng Chen
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 409.
https://doi.org/10.1158/1538-7445.AM2022-409
Published: 15 June 2022
View articletitled, Abstract 409: Reversal of ABCG2-mediated multidrug resistance by tepotinib in vitro and in vivo
Journal Articles

Abstract 407: OTS964, a TOPK inhibitor, is susceptible to ABCG2-mediated drug resistance

Yuqi Yang, Zhuo-Xun Wu, Jing-Quan Wang, Qiu-Xu Teng, Zi-Ning Lei, Sabrina Lusvarghi, Suresh V. Ambudkar, Ning Ji, Zhe-Sheng Chen
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 407.
https://doi.org/10.1158/1538-7445.AM2022-407
Published: 15 June 2022
View articletitled, Abstract 407: OTS964, a TOPK inhibitor, is susceptible to ABCG2-mediated drug resistance
Journal Articles

Abstract PS1-30: A prospective phase II trial to evaluate the feasibility of omit sentinel lymph node biopsy after integrate18F-FDG dedicated axillary PET in early breast cancer: SOAPET trial

Junjie Li, Jingyi Cheng, Guangyu Liu, Yifeng Hou, Genghong Di, Benlong Yang, Yizhou Jiang, Liang Huang, Sheng Chen, Yan Wang, Keda Yu, Zhimin Shao
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS1-30.
https://doi.org/10.1158/1538-7445.SABCS20-PS1-30
Published: 15 February 2021
View articletitled, Abstract PS1-30: A prospective phase II trial to evaluate the feasibility of omit sentinel lymph node biopsy after integrate18F-FDG dedicated axillary PET in early breast cancer: SOAPET trial
Journal Articles

Abstract 2487: Mutation of the STK11 gene predicts recurrence of breast cancer

Chih-Yang Wang, Yung-Chieh Chang, Yao-Lung Kuo, Kuo-Ting Lee, Pai-Sheng Chen, Chun Hei Antonio Cheung, Che-Hung Shen, Chih-Peng Chang, Ming-Derg Lai, Meng-Ru Shen, Hui-Ping Hsu
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2487.
https://doi.org/10.1158/1538-7445.AM2020-2487
Published: 15 August 2020
View articletitled, Abstract 2487: Mutation of the STK11 gene predicts recurrence of breast cancer
Journal Articles

Abstract 2983: A synthetic derivative of 1,2,3-triazole-pyrimidine hybrid reverses multidrug resistance mediated by MRP7

Jing-Quan Wang, Zi-Ning Lei, Qiu-Xu Teng, Bo Wang, Li-Ying Ma, Hong-Min Liu, Zhe-Sheng Chen
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2983.
https://doi.org/10.1158/1538-7445.AM2020-2983
Published: 15 August 2020
View articletitled, Abstract 2983: A synthetic derivative of 1,2,3-triazole-pyrimidine hybrid reverses multidrug resistance mediated by MRP7
Journal Articles

Abstract 3006: Anticancer and multidrug resistance-reversing activities of novel antimicrobial peptides

Qiu-Xu Teng, Zi-Ning Lei, Xiaofang Luo, Jing-Quan Wang, Zuodong Qin, John N. Wurpel, Zhe-Sheng Chen
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3006.
https://doi.org/10.1158/1538-7445.AM2020-3006
Published: 15 August 2020
View articletitled, Abstract 3006: Anticancer and multidrug resistance-reversing activities of novel antimicrobial peptides
Journal Articles

Abstract 3010: VKNG 1 reverses multidrug resistance by inhibiting ABCG2 mediated drug transport in vitro and in vivo

Silpa Narayanan, Nehaben A. Gujarati, Qiuxu Teng, Jingquan Wang, Chao-Yun Cai, Yuqi Yang, Anirudh Jaganna Chintalapati, Vijaya L. Korlipara, Zhe-Sheng Chen
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3010.
https://doi.org/10.1158/1538-7445.AM2020-3010
Published: 15 August 2020
View articletitled, Abstract 3010: VKNG 1 reverses multidrug resistance by inhibiting ABCG2 mediated drug transport in vitro and in vivo
Journal Articles

Abstract 5264: Selective toxicity of MX-106-4C, a survivin inhibitor, in P-glycoprotein-mediated multidrug resistant colon cancer

Zi-Ning Lei, Zhongzhi Wu, Qiu-Xu Teng, Min Xiao, Wei Li, John N. Wurpel, Zhe-Sheng Chen
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5264.
https://doi.org/10.1158/1538-7445.AM2020-5264
Published: 15 August 2020
View articletitled, Abstract 5264: Selective toxicity of MX-106-4C, a survivin inhibitor, in P-glycoprotein-mediated multidrug resistant colon cancer
Journal Articles

Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGFβ Signaling

Jian Chen, Abhisek Mitra, Shulin Li, Shumei Song, Bao-Ngoc Nguyen, Jiun-Sheng Chen, Ji-Hyun Shin, Nancy R. Gough, Paul Lin, Vincent Obias, Aiwu Ruth He, Zhixing Yao, Tathiane M. Malta, Houtan Noushmehr, Patricia S. Latham, Xiaoping Su, Asif Rashid, Bibhuti Mishra, Ray-Chang Wu, Lopa Mishra
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (9): 1819–1832.
https://doi.org/10.1158/0008-5472.CAN-19-3116
Published: 04 May 2020
View articletitled, Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGFβ Signaling
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Includes: Supplementary data