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Sharon R. Pine
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Journal Articles

Abstract 6496: Assessment of tyrosine kinase inhibitor bypass mechanisms in lung cancer using single cell multiomics, patient derived organoids and rationally designed drug screens

Liqiong Liu, Ann Strange, Schuyler Lee, Bifeng Gao, Daniel Merrick, Tejas Patil, James DeGregori, D Ross Camidge, Sharon R. Pine, Hatim E. Sabaawy
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6496.
https://doi.org/10.1158/1538-7445.AM2024-6496
Published: 22 March 2024
View article titled, Abstract 6496: Assessment of tyrosine kinase inhibitor bypass mechanisms in lung cancer using single cell multiomics, patient derived organoids and rationally designed drug screens
Journal Articles

Abstract 272: Autophagy and MEK inhibition promotes ferroptosis in liver kinase B1 (Lkb1)-deficient Kras-driven lung tumors

Vrushank Bhatt, Taijin Lan, Wenping Wang, Jerry Kong, Eduardo Cararo Lopes, Khoosheh Khayati, Jianming Wang, Akash Raju, Michael Rangel, Enrique Lopez, Zhixian Sherrie Hu, Xuefei Luo, Xiaoyang Su, Jyoti Malhotra, Wenwei Hu, Sharon R. Pine, Eileen White, Jessie Yanxiang Guo
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 272.
https://doi.org/10.1158/1538-7445.AM2023-272
Published: 04 April 2023
View article titled, Abstract 272: Autophagy and MEK inhibition promotes ferroptosis in liver kinase B1 (Lkb1)-deficient Kras-driven lung tumors
Journal Articles

FILIP1L Loss Is a Driver of Aggressive Mucinous Colorectal Adenocarcinoma and Mediates Cytokinesis Defects through PFDN1

Mijung Kwon, Genesaret Rubio, Nicholas Nolan, Peter Auteri, Jean Arly Volmar, Asha Adem, Parisa Javidian, Zhongren Zhou, Michael P. Verzi, Sharon R. Pine, Steven K. Libutti
Journal: Cancer Research
Cancer Res (2021) 81 (21): 5523–5539.
https://doi.org/10.1158/0008-5472.CAN-21-0897
Published: 01 November 2021
View article titled, FILIP1L Loss Is a Driver of Aggressive Mucinous Colorectal Adenocarcinoma and Mediates Cytokinesis Defects through PFDN1
Open the PDF for FILIP1L Loss Is a Driver of Aggressive Mucinous Colorectal Adenocarcinoma and Mediates Cytokinesis Defects through PFDN1 in another window
Includes: Supplementary data
Journal Articles

Abstract 4834: Preclinical analysis of the Notch gamma secretase inhibitor BMS-906024 in combination with chemotherapy in the treatment of lung adenocarcinoma

Katherine M. Morgan, Francis Lee, Erin Michaud, Bruce S. Fischer, Sharon R. Pine
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4834.
https://doi.org/10.1158/1538-7445.AM2016-4834
Published: 15 July 2016
View article titled, Abstract 4834: Preclinical analysis of the Notch gamma secretase inhibitor BMS-906024 in combination with chemotherapy in the treatment of lung adenocarcinoma
Journal Articles

Abstract 4544: FBW7 induces S-phase arrest caused by DNA double strand breaks through targeting SOX9 for proteasomal degradation

Xuehui Hong, Wenyu Liu, Ruipeng Song, Hiroyuki Inuzuka, Hatem E. Sabaawy, Katherine M. Morgan, Jamie J. Shah, Samuel F. Bunting, Xing Feng, Chi-Kwan Tsang, Zhiyuan Shen, X. F. Steven Zheng, LianXin Liu, Sharon R. Pine
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4544.
https://doi.org/10.1158/1538-7445.AM2016-4544
Published: 15 July 2016
View article titled, Abstract 4544: FBW7 induces S-phase arrest caused by DNA double strand breaks through targeting SOX9 for proteasomal degradation
Journal Articles

Abstract 1957: Negative regulation of Sox9 by glycogen synthase kinase 3 beta phosphorylation and SCFFbw7-dependent ubiquitination in cancer

Xuehui Hong, Wenyu Liu, Hiroyuki Inuzuka, Lianxin Liu, Sharon R. Pine
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1957.
https://doi.org/10.1158/1538-7445.AM2015-1957
Published: 01 August 2015
View article titled, Abstract 1957: Negative regulation of Sox9 by glycogen synthase kinase 3 beta phosphorylation and SCFFbw7-dependent ubiquitination in cancer
Journal Articles

Abstract 2535: Synergistic anti-tumor activity of the Notch gamma secretase inhibitor BMS-906024 and paclitaxel in the treatment of lung adenocarcinoma

Katherine M. Morgan, Francis Lee, Erin Michaud, Joseph R. Bertino, Bruce S. Fischer, Sharon R. Pine
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2535.
https://doi.org/10.1158/1538-7445.AM2015-2535
Published: 01 August 2015
View article titled, Abstract 2535: Synergistic anti-tumor activity of the Notch gamma secretase inhibitor BMS-906024 and paclitaxel in the treatment of lung adenocarcinoma
Journal Articles

Identification of a Functional SNP in the 3′UTR of CXCR2 That Is Associated with Reduced Risk of Lung Cancer

Bríd M. Ryan, Ana I. Robles, Andrew C. McClary, Majda Haznadar, Elise D. Bowman, Sharon R. Pine, Derek Brown, Mohammed Khan, Kouya Shiraishi, Takashi Kohno, Hirokazu Okayama, Ramakrishna Modali, Jun Yokota, Curtis C. Harris
Journal: Cancer Research
Cancer Res (2015) 75 (3): 566–575.
https://doi.org/10.1158/0008-5472.CAN-14-2101
Published: 01 February 2015
View article titled, Identification of a Functional SNP in the 3′UTR of CXCR2 That Is Associated with Reduced Risk of Lung Cancer
Open the PDF for Identification of a Functional SNP in the 3′UTR of CXCR2 That Is Associated with Reduced Risk of Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract B1: p53 isoforms, Δ133p53 and p53β, regulate aging-associated T lymphocyte senescence.

Abdul Matin Mondal, Izumi Horikawa, Sharon R. Pine, Kaori Fujita, Borivoj Vojtesek, Jean-Christophe Bourdon, Elsa Vera, David P. Lane, Maria A. Blasco, Curtis C. Harris
Journal: Cancer Research
Cancer Res (2011) 71 (18_Supplement): B1.
https://doi.org/10.1158/1538-7445.FBCR11-B1
Published: 28 October 2014
View article titled, Abstract B1: p53 isoforms, Δ133p53 and p53β, regulate aging-associated T lymphocyte senescence.
Journal Articles

Abstract 1149: The role of the novel Notch1-Sox9 signaling axis in NSCLC progression and EMT

Kathleen M. Capaccione, Xuehui Hong, Katherine M. Morgan, Thaddeus D. Allen, Gregory D. Miles, Elke K. Markert, J. Michael Bishop, Sharon R. Pine
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1149.
https://doi.org/10.1158/1538-7445.AM2014-1149
Published: 01 October 2014
View article titled, Abstract 1149: The role of the novel Notch1-Sox9 signaling axis in NSCLC progression and EMT
Journal Articles

Abstract 2915: p53 isoforms Δ133p53 and p53β are endogenous regulators of replicative cellular senescence

Kaori Fujita, Abdul M. Mondal, Izumi Horikawa, Giang H. Nguyen, Kensuke Kumamoto, Jane J. Sohn, Elise D. Bowman, Mathe A. Mathe, Aaron J. Schetter, Sharon R. Pine, Helen Ji, Borivoj Vojtesek, Jean-Christophe Bourdon, David P. Lane, Curtis C. Harris
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2915.
https://doi.org/10.1158/1538-7445.AM10-2915
Published: 15 April 2010
View article titled, Abstract 2915: p53 isoforms Δ133p53 and p53β are endogenous regulators of replicative cellular senescence
Journal Articles

Abstract 4238: Human non-small cell lung cancer cells asymmetrically divide their template DNA strands and cell fate proteins

Sharon R. Pine, Brid M. Ryan, Lyuba Varticovski, Ana I. Robles, Curtis C. Harris
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4238.
https://doi.org/10.1158/1538-7445.AM10-4238
Published: 15 April 2010
View article titled, Abstract 4238: Human non-small cell lung cancer cells asymmetrically divide their template DNA strands and cell fate proteins